Peptide inhibitors disrupt the serotonin 5-HT2C receptor interaction with phosphatase and tensin homolog to allosterically modulate cellular signaling and behavior

Journal of Neuroscience

Volumn 33, Issue 4, 2013, Pages 1615-1630

  Anastasio, Noelle C ^a,b   Gilbertson, Scott R ^a,c   Bubar, Marcy J ^a   Agarkov, Anton ^c   Stutz, Sonja J ^a,b   Jeng, Yowjiun ^a,b   Bremer, Nicole M ^a,b   Smith, Thressa D ^a,b   Fox, Robert G ^a,b   Swinford, Sarah E ^a   Seitz, Patricia K ^a,b   Charendoff, Marc N ^d   Craft, John W ^d   Laezza, Fernanda M ^a,b   Watson, Cheryl S ^a,b   Briggs, James M ^d   Cunningham, Kathryn A ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c University of Houston   (United States)

^d UNIVERSITY OF HOUSTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1, 2, 3, 4, 8, 9, 10, 10A OCTAHYDRO 7BH CYCLOPENTA [B] [1, 4] DIAZEPINO [6, 7, 1 HI] INDOLE; PHOSPHATIDYLINOSITOL 3, 4, 5 TRISPHOSPHATE 3 PHOSPHATASE; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; CIRCULAR DICHROISM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; IMMUNOPRECIPITATION; LOCOMOTION; MALE; MASS SPECTROMETRY; MOLECULAR DOCKING; MOLECULAR DYNAMICS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SIMULATION; TASK PERFORMANCE; TRAINING;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MALE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOTOR ACTIVITY; PEPTIDE FRAGMENTS; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2C; SEROTONIN; SIGNAL TRANSDUCTION; TRANSFECTION;

EID: 84872696152     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.2656-12.2013     Document Type: Article

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