Selective serotonin 5-HT2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues

Neuropharmacology

Volumn 61, Issue 3, 2011, Pages 513-523

  Cunningham, Kathryn A ^a   Fox, Robert G ^a   Anastasio, Noelle C ^a   Bubar, Marcy J ^a   Stutz, Sonja J ^a   Moeller, F Gerard ^b   Gilbertson, Scott R ^c   Rosenzweig Lipson, Sharon ^d,e  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS   (United States)

^c University of Houston   (United States)

^d PFIZER INC   (United States)

^e In Vivo Solutions   (United States)

Author keywords

5 HT2C receptor; Addiction; Cocaine; Reward; Self administration; Serotonin; Sucrose; WAY 163909

Indexed keywords

1,2,3,4,8,9,10,10A OCTAHYDRO 7BH CYCLOPENTA[B][1,4]DIAZEPINO[6,7,1 HI]INDOLE; 2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 6 CHLORO 2 (1 PIPERAZINYL)PYRAZINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; COCAINE; SEROTONIN 2C RECEPTOR; SUCROSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SELF ADMINISTRATION; LOCOMOTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; REINFORCEMENT; CONFERENCE PAPER; PHARMACOLOGICAL BLOCKING; STIMULUS RESPONSE; TREATMENT RESPONSE;

ANIMALS; AZEPINES; BEHAVIOR, ANIMAL; COCAINE; COCAINE-RELATED DISORDERS; CUES; DIETARY SUCROSE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEEDING BEHAVIOR; IMPULSIVE BEHAVIOR; INDOLES; MALE; MOTOR ACTIVITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2C; REWARD; SELF ADMINISTRATION; SEROTONIN 5-HT2 RECEPTOR AGONISTS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS;

EID: 80955177188     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.04.034     Document Type: Article

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