메뉴 건너뛰기




Volumn 113, Issue 6, 2010, Pages 1504-1515

Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex

Author keywords

5 HT2C receptor; 5 HT2C receptor localization; Motor cortex; Post synaptic density; Prefrontal cortex

Indexed keywords

POSTSYNAPTIC DENSITY PROTEIN 95; RECEPTOR ANTIBODY; SEROTONIN 5 RECEPTOR; SEROTONIN 5 RECEPTOR 2C; UNCLASSIFIED DRUG; SEROTONIN 2C RECEPTOR;

EID: 77953100223     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06694.x     Document Type: Article
Times cited : (35)

References (55)
  • 2
    • 66749118877 scopus 로고    scopus 로고
    • PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors
    • Abbas A. I., Yadav P. N., Yao W. D., Arbuckle M. I., Grant S. G., Caron M. G. Roth B. L. (2009) PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. J. Neurosci. 29, 7124 7136.
    • (2009) J. Neurosci. , vol.29 , pp. 7124-7136
    • Abbas, A.I.1    Yadav, P.N.2    Yao, W.D.3    Arbuckle, M.I.4    Grant, S.G.5    Caron, M.G.6    Roth, B.L.7
  • 3
    • 0028983327 scopus 로고
    • Identification of the 5-hydroxytryptamine2C receptor as a 60-kDa N-glycosylated protein in choroid plexus and hippocampus
    • Abramowski D. Staufenbiel M. (1995) Identification of the 5-hydroxytryptamine2C receptor as a 60-kDa N-glycosylated protein in choroid plexus and hippocampus. J. Neurochem. 65, 782 790.
    • (1995) J. Neurochem. , vol.65 , pp. 782-790
    • Abramowski, D.1    Staufenbiel, M.2
  • 5
    • 0029129068 scopus 로고
    • Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides
    • Backstrom J. R., Westphal R. S., Canton H. Sanders-Bush E. (1995) Identification of rat serotonin 5-HT2C receptors as glycoproteins containing N-linked oligosaccharides. Brain Res. Mol. Brain Res. 33, 311 318.
    • (1995) Brain Res. Mol. Brain Res. , vol.33 , pp. 311-318
    • Backstrom, J.R.1    Westphal, R.S.2    Canton, H.3    Sanders-Bush, E.4
  • 9
    • 0028245594 scopus 로고
    • A molecular description of synaptic vesicle membrane trafficking
    • Bennett M. K. Scheller R. H. (1994) A molecular description of synaptic vesicle membrane trafficking. Annu. Rev. Biochem. 63, 63 100.
    • (1994) Annu. Rev. Biochem. , vol.63 , pp. 63-100
    • Bennett, M.K.1    Scheller, R.H.2
  • 10
    • 0031815337 scopus 로고    scopus 로고
    • Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: Evidence for agonist-directed trafficking of receptor stimulus
    • Berg K. A., Maayani S., Goldfarb J., Scaramellini C., Leff P. Clarke W. P. (1998) Effector pathway-dependent relative efficacy at serotonin type 2A and 2C receptors: evidence for agonist-directed trafficking of receptor stimulus. Mol. Pharmacol. 54, 94 104.
    • (1998) Mol. Pharmacol. , vol.54 , pp. 94-104
    • Berg, K.A.1    Maayani, S.2    Goldfarb, J.3    Scaramellini, C.4    Leff, P.5    Clarke, W.P.6
  • 11
    • 0034757919 scopus 로고    scopus 로고
    • Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation
    • Berg K. A., Stout B. D., Maayani S. Clarke W. P. (2001) Differences in rapid desensitization of 5-hydroxytryptamine2A and 5-hydroxytryptamine2C receptor-mediated phospholipase C activation. J. Pharmacol. Exp. Ther. 299, 593 602.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 593-602
    • Berg, K.A.1    Stout, B.D.2    Maayani, S.3    Clarke, W.P.4
  • 13
    • 0030624419 scopus 로고    scopus 로고
    • Synaptosomes. A model system to study release of multiple classes of neurotransmitters
    • Breukel A. I., Besselsen E. Ghijsen W. E. (1997) Synaptosomes. A model system to study release of multiple classes of neurotransmitters. Methods Mol. Biol. 72, 33 47.
    • (1997) Methods Mol. Biol. , vol.72 , pp. 33-47
    • Breukel, A.I.1    Besselsen, E.2    Ghijsen, W.E.3
  • 14
    • 34247469816 scopus 로고    scopus 로고
    • Distribution of serotonin 5-HT2C receptors in the ventral tegmental area
    • Bubar M. J. Cunningham K. A. (2007) Distribution of serotonin 5-HT2C receptors in the ventral tegmental area. Neuroscience 146, 286 297.
    • (2007) Neuroscience , vol.146 , pp. 286-297
    • Bubar, M.J.1    Cunningham, K.A.2
  • 16
    • 57649121946 scopus 로고    scopus 로고
    • Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade
    • Calcagno E., Carli M., Baviera M. Invernizzi R. W. (2009) Endogenous serotonin and serotonin2C receptors are involved in the ability of M100907 to suppress cortical glutamate release induced by NMDA receptor blockade. J. Neurochem. 108, 521 532.
    • (2009) J. Neurochem. , vol.108 , pp. 521-532
    • Calcagno, E.1    Carli, M.2    Baviera, M.3    Invernizzi, R.W.4
  • 17
    • 0037104778 scopus 로고    scopus 로고
    • Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism
    • Carr D. B., Cooper D. C., Ulrich S. L., Spruston N. Surmeier D. J. (2002) Serotonin receptor activation inhibits sodium current and dendritic excitability in prefrontal cortex via a protein kinase C-dependent mechanism. J. Neurosci. 22, 6846 6855.
    • (2002) J. Neurosci. , vol.22 , pp. 6846-6855
    • Carr, D.B.1    Cooper, D.C.2    Ulrich, S.L.3    Spruston, N.4    Surmeier, D.J.5
  • 18
    • 0033991116 scopus 로고    scopus 로고
    • Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS
    • Clemett D. A., Punhani T., Duxon M. S., Blackburn T. P. Fone K. C. (2000) Immunohistochemical localisation of the 5-HT2C receptor protein in the rat CNS. Neuropharmacology 39, 123 132.
    • (2000) Neuropharmacology , vol.39 , pp. 123-132
    • Clemett, D.A.1    Punhani, T.2    Duxon, M.S.3    Blackburn, T.P.4    Fone, K.C.5
  • 21
    • 68949169222 scopus 로고    scopus 로고
    • Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait
    • Dracheva S., Lyddon R., Barley K., Marcus S. M., Hurd Y. L. Byne W. M. (2009) Editing of serotonin 2C receptor mRNA in the prefrontal cortex characterizes high-novelty locomotor response behavioral trait. Neuropsychopharmacol. 34, 2237 2251.
    • (2009) Neuropsychopharmacol. , vol.34 , pp. 2237-2251
    • Dracheva, S.1    Lyddon, R.2    Barley, K.3    Marcus, S.M.4    Hurd, Y.L.5    Byne, W.M.6
  • 22
  • 24
    • 0037960939 scopus 로고    scopus 로고
    • Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex
    • Filip M. Cunningham K. A. (2003) Hyperlocomotive and discriminative stimulus effects of cocaine are under the control of serotonin(2C) (5-HT(2C)) receptors in rat prefrontal cortex. J. Pharmacol. Exp. Ther. 306, 734 743.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 734-743
    • Filip, M.1    Cunningham, K.A.2
  • 25
    • 0033625998 scopus 로고    scopus 로고
    • 5-HT2C receptor binding is increased in the substantia nigra pars reticulata in Parkinson's disease
    • Fox S. H. Brotchie J. M. (2000) 5-HT2C receptor binding is increased in the substantia nigra pars reticulata in Parkinson's disease. Mov. Disord. 15, 1064 1069.
    • (2000) Mov. Disord. , vol.15 , pp. 1064-1069
    • Fox, S.H.1    Brotchie, J.M.2
  • 26
    • 3042670429 scopus 로고    scopus 로고
    • Molecular and functional characterization of proteins interacting with the C-terminal domains of 5-HT2 receptors: Emergence of 5-HT2 'Receptosomes'
    • Gavarini S., Becamel C., Chanrion B., Bockaert J. Marin P. (2004) Molecular and functional characterization of proteins interacting with the C-terminal domains of 5-HT2 receptors: emergence of 5-HT2 'Receptosomes'. Biol. Cell 96, 373 381.
    • (2004) Biol. Cell , vol.96 , pp. 373-381
    • Gavarini, S.1    Becamel, C.2    Chanrion, B.3    Bockaert, J.4    Marin, P.5
  • 27
    • 33750501125 scopus 로고    scopus 로고
    • Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability
    • Gavarini S., Becamel C., Altier C., Lory P., Poncet J., Wijnholds J., Bockaert J. Marin P. (2006) Opposite effects of PSD-95 and MPP3 PDZ proteins on serotonin 5-hydroxytryptamine2C receptor desensitization and membrane stability. Mol. Biol. Cell 17, 4619 4631.
    • (2006) Mol. Biol. Cell , vol.17 , pp. 4619-4631
    • Gavarini, S.1    Becamel, C.2    Altier, C.3    Lory, P.4    Poncet, J.5    Wijnholds, J.6    Bockaert, J.7    Marin, P.8
  • 28
    • 1642285042 scopus 로고    scopus 로고
    • Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems
    • Giorgetti M. Tecott L. H. (2004) Contributions of 5-HT(2C) receptors to multiple actions of central serotonin systems. Eur. J. Pharmacol. 488, 1 9.
    • (2004) Eur. J. Pharmacol. , vol.488 , pp. 1-9
    • Giorgetti, M.1    Tecott, L.H.2
  • 29
    • 0032032619 scopus 로고    scopus 로고
    • Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken
    • Hamada S., Senzaki K., Hamaguchi-Hamada K., Tabuchi K., Yamamoto H., Yamamoto T., Yoshikawa S., Okano H. Okado N. (1998) Localization of 5-HT2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken. Mol. Brain Res. 54, 199 211.
    • (1998) Mol. Brain Res. , vol.54 , pp. 199-211
    • Hamada, S.1    Senzaki, K.2    Hamaguchi-Hamada, K.3    Tabuchi, K.4    Yamamoto, H.5    Yamamoto, T.6    Yoshikawa, S.7    Okano, H.8    Okado, N.9
  • 31
    • 8344290547 scopus 로고    scopus 로고
    • Biochemical and biophysical characterization of serotonin 5-HT2C receptor homodimers on the plasma membrane of living cells
    • Herrick-Davis K., Grinde E. Mazurkiewicz J. E. (2004) Biochemical and biophysical characterization of serotonin 5-HT2C receptor homodimers on the plasma membrane of living cells. Biochemistry 43, 13963 13971.
    • (2004) Biochemistry , vol.43 , pp. 13963-13971
    • Herrick-Davis, K.1    Grinde, E.2    Mazurkiewicz, J.E.3
  • 32
    • 0024603445 scopus 로고
    • Distribution of serotonin 5-HT1C receptor mRNA in adult rat brain
    • Hoffman B. J. Mezey E. (1989) Distribution of serotonin 5-HT1C receptor mRNA in adult rat brain. FEBS Lett. 247, 453 462.
    • (1989) FEBS Lett. , vol.247 , pp. 453-462
    • Hoffman, B.J.1    Mezey, E.2
  • 33
    • 0029962955 scopus 로고    scopus 로고
    • PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses
    • Hunt C. A., Schenker L. J. Kennedy M. B. (1996) PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses. J. Neurosci. 16, 1380 1388.
    • (1996) J. Neurosci. , vol.16 , pp. 1380-1388
    • Hunt, C.A.1    Schenker, L.J.2    Kennedy, M.B.3
  • 34
    • 0023740032 scopus 로고
    • Molecular characterization of a functional cDNA encoding the serotonin 1C receptor
    • Julius D., MacDermott A. B., Axel R. Jessell J. M. (1988a) Molecular characterization of a functional cDNA encoding the serotonin 1C receptor. Science 241, 558 564.
    • (1988) Science , vol.241 , pp. 558-564
    • Julius, D.1    MacDermott, A.B.2    Axel, R.3    Jessell, J.M.4
  • 37
    • 58549100704 scopus 로고    scopus 로고
    • Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens
    • Leggio G. M., Cathala A., Moison D., Cunningham K. A., Piazza P. V. Spampinato U. (2009) Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens. Neuropharmacology 56, 507 513.
    • (2009) Neuropharmacology , vol.56 , pp. 507-513
    • Leggio, G.M.1    Cathala, A.2    Moison, D.3    Cunningham, K.A.4    Piazza, P.V.5    Spampinato, U.6
  • 38
    • 58749106045 scopus 로고    scopus 로고
    • Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine
    • Leventopoulos M., Russig H., Feldon J., Pryce C. R. Opacka-Juffry J. (2009) Early deprivation leads to long-term reductions in motivation for reward and 5-HT1A binding and both effects are reversed by fluoxetine. Neuropharmacology 56, 692 701.
    • (2009) Neuropharmacology , vol.56 , pp. 692-701
    • Leventopoulos, M.1    Russig, H.2    Feldon, J.3    Pryce, C.R.4    Opacka-Juffry, J.5
  • 39
    • 34249014117 scopus 로고    scopus 로고
    • Serotonin(2C) receptor localization in GABA neurons of the rat medial prefrontal cortex: Implications for understanding the neurobiology of addiction
    • Liu S., Bubar M. J., Lanfranco M. F., Hillman G. R. Cunningham K. A. (2007) Serotonin(2C) receptor localization in GABA neurons of the rat medial prefrontal cortex: implications for understanding the neurobiology of addiction. Neuroscience 146, 1667 1688.
    • (2007) Neuroscience , vol.146 , pp. 1667-1688
    • Liu, S.1    Bubar, M.J.2    Lanfranco, M.F.3    Hillman, G.R.4    Cunningham, K.A.5
  • 40
    • 0036141126 scopus 로고    scopus 로고
    • Serotonin 5- HT (2C) receptor knockout mice: Autoradiographic analysis of multiple serotonin receptors
    • Lopez-Gimenez J. F., Tecott L. H., Palacios J. M., Mengod G. Vilaro M. T. (2002) Serotonin 5- HT (2C) receptor knockout mice: autoradiographic analysis of multiple serotonin receptors. J. Neurosci. Res. 67, 69 85.
    • (2002) J. Neurosci. Res. , vol.67 , pp. 69-85
    • Lopez-Gimenez, J.F.1    Tecott, L.H.2    Palacios, J.M.3    Mengod, G.4    Vilaro, M.T.5
  • 41
    • 48749126827 scopus 로고    scopus 로고
    • Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor
    • Mancia F., Assur Z., Herman A. G., Siegel R. Hendrickson W. A. (2008) Ligand sensitivity in dimeric associations of the serotonin 5HT2c receptor. EMBO Rep. 9, 363 369.
    • (2008) EMBO Rep. , vol.9 , pp. 363-369
    • Mancia, F.1    Assur, Z.2    Herman, A.G.3    Siegel, R.4    Hendrickson, W.A.5
  • 42
    • 0025124833 scopus 로고
    • 2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites
    • 2 receptor by in situ hybridization histochemistry. Correlation with the distribution of receptor sites. Brain Res. 524, 139 143.
    • (1990) Brain Res. , vol.524 , pp. 139-143
    • Mengod, G.1    Pompeiano, M.2    Martínez-Mir, M.I.3    Palacios, J.M.4
  • 44
    • 0024722805 scopus 로고
    • 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system
    • Molineaux S. M., Jessell T. M., Axel R. Julius D. (1989) 5-HT1c receptor is a prominent serotonin receptor subtype in the central nervous system. Proc. Natl Acad. Sci. USA 86, 6793 6797.
    • (1989) Proc. Natl Acad. Sci. USA , vol.86 , pp. 6793-6797
    • Molineaux, S.M.1    Jessell, T.M.2    Axel, R.3    Julius, D.4
  • 45
    • 33846491960 scopus 로고    scopus 로고
    • Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: A proteomic study focusing on endocytic proteins
    • Moron J. A., bul-Husn N. S., Rozenfeld R., Dolios G., Wang R. Devi L. A. (2007) Morphine administration alters the profile of hippocampal postsynaptic density-associated proteins: A proteomic study focusing on endocytic proteins. Mol. Cell Proteomics 6, 29 42.
    • (2007) Mol. Cell Proteomics , vol.6 , pp. 29-42
    • Moron, J.A.1    Bul-Husn, N.S.2    Rozenfeld, R.3    Dolios, G.4    Wang, R.5    Devi, L.A.6
  • 47
    • 0002264575 scopus 로고    scopus 로고
    • Identification and characterization of RNA editing events within the 5-HT2C receptor
    • Niswender C. M., Sanders-Bush E. Emeson R. B. (1998) Identification and characterization of RNA editing events within the 5-HT2C receptor. Ann. N Y Acad. Sci. 861, 38 48.
    • (1998) Ann. N y Acad. Sci. , vol.861 , pp. 38-48
    • Niswender, C.M.1    Sanders-Bush, E.2    Emeson, R.B.3
  • 49
    • 17944375149 scopus 로고    scopus 로고
    • The presynaptic particle web: Ultrastructure, composition, dissolution, and reconstitution
    • Phillips G. R., Huang J. K., Wang Y. et al. (2001) The presynaptic particle web: ultrastructure, composition, dissolution, and reconstitution. Neuron 32, 63 77.
    • (2001) Neuron , vol.32 , pp. 63-77
    • Phillips, G.R.1    Huang, J.K.2    Wang, Y.3
  • 51
    • 0344564203 scopus 로고    scopus 로고
    • Subcellular distribution of 5-hydroxytryptamine2A and N-methyl-D-aspartate receptors within single neurons in rat motor and limbic striatum
    • Rodriguez J. J., Garcia D. R. Pickel V. M. (1999) Subcellular distribution of 5-hydroxytryptamine2A and N-methyl-D-aspartate receptors within single neurons in rat motor and limbic striatum. J. Comp. Neurol. 413, 219 231.
    • (1999) J. Comp. Neurol. , vol.413 , pp. 219-231
    • Rodriguez, J.J.1    Garcia, D.R.2    Pickel, V.M.3
  • 52
    • 2642559632 scopus 로고    scopus 로고
    • Serotonin 5-HT2 receptors: Molecular and genomic diversity
    • Sanders-Bush E., Fentress H. Hazelwood L. (2003) Serotonin 5-HT2 receptors: molecular and genomic diversity. Mol. Interv. 3, 319 330.
    • (2003) Mol. Interv. , vol.3 , pp. 319-330
    • Sanders-Bush, E.1    Fentress, H.2    Hazelwood, L.3
  • 54
    • 0030612256 scopus 로고    scopus 로고
    • 2C receptor protein in adult rat brain and spinal cord determined using a receptor- directed antibody: Effect of 5,7-dihydroxytryptamine
    • 2C receptor protein in adult rat brain and spinal cord determined using a receptor- directed antibody: Effect of 5,7-dihydroxytryptamine. Synapse 27, 45 56.
    • (1997) Synapse , vol.27 , pp. 45-56
    • Sharma, A.1    Punhani, T.2    Fone, K.C.F.3
  • 55
    • 34548436564 scopus 로고    scopus 로고
    • The postsynaptic architecture of excitatory synapses: A more quantitative view
    • Sheng M. Hoogenraad C. C. (2007) The postsynaptic architecture of excitatory synapses: a more quantitative view. Annu. Rev. Biochem. 76, 823 847.
    • (2007) Annu. Rev. Biochem. , vol.76 , pp. 823-847
    • Sheng, M.1    Hoogenraad, C.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.