메뉴 건너뛰기




Volumn 366, Issue 2, 2013, Pages 215-223

AMPK and the neuroendocrine regulation of appetite and energy expenditure

Author keywords

[No Author keywords available]

Indexed keywords

ACETYL COENZYME A CARBOXYLASE; ADENOSINE TRIPHOSPHATE; ADIPONECTIN; CARNITINE PALMITOYLTRANSFERASE I; GHRELIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; LEPTIN; THYROID HORMONE;

EID: 84872663273     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2012.06.012     Document Type: Review
Times cited : (75)

References (84)
  • 2
    • 0001650670 scopus 로고
    • Hypothalamic control of food intake in rats and cats
    • Anand B.K., Brobeck J.R. Hypothalamic control of food intake in rats and cats. Yale J. Biol. Med. 1951, 1-25.
    • (1951) Yale J. Biol. Med. , pp. 1-25
    • Anand, B.K.1    Brobeck, J.R.2
  • 5
    • 81755172024 scopus 로고    scopus 로고
    • Central mechanisms involved in the orexigenic actions of ghrelin
    • Andrews Z.B. Central mechanisms involved in the orexigenic actions of ghrelin. Peptides 2011, 32:2248-2255.
    • (2011) Peptides , vol.32 , pp. 2248-2255
    • Andrews, Z.B.1
  • 6
    • 27644448810 scopus 로고    scopus 로고
    • Mitochondrial uncoupling proteins in the CNS: in support of function and survival
    • Andrews Z.B., Diano S., Horvath T.L. Mitochondrial uncoupling proteins in the CNS: in support of function and survival. Nat. Rev. Neurosci. 2005, 6:829-840.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 829-840
    • Andrews, Z.B.1    Diano, S.2    Horvath, T.L.3
  • 11
    • 79951682389 scopus 로고    scopus 로고
    • Metabolic status regulates ghrelin function on energy homeostasis
    • Briggs D.I., Andrews Z.B. Metabolic status regulates ghrelin function on energy homeostasis. Neuroendocrinology 2011, 93:48-57.
    • (2011) Neuroendocrinology , vol.93 , pp. 48-57
    • Briggs, D.I.1    Andrews, Z.B.2
  • 13
    • 33947357840 scopus 로고    scopus 로고
    • Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: additive effects of leptin or insulin
    • Cai F., Gyulkhandanyan A.V., Wheeler M.B., Belsham D.D. Glucose regulates AMP-activated protein kinase activity and gene expression in clonal, hypothalamic neurons expressing proopiomelanocortin: additive effects of leptin or insulin. J. Endocrinol. 2007, 192:605-614.
    • (2007) J. Endocrinol. , vol.192 , pp. 605-614
    • Cai, F.1    Gyulkhandanyan, A.V.2    Wheeler, M.B.3    Belsham, D.D.4
  • 23
    • 67049146814 scopus 로고    scopus 로고
    • Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes
    • Fan X., Ding Y., Brown S., Zhou L., Shaw M., Vella M.C., Cheng H., McNay E.C., Sherwin R.S., McCrimmon R.J. Hypothalamic AMP-activated protein kinase activation with AICAR amplifies counterregulatory responses to hypoglycemia in a rodent model of type 1 diabetes. Am. J. Physiol. 2009, 296:R1702-R1708.
    • (2009) Am. J. Physiol. , vol.296
    • Fan, X.1    Ding, Y.2    Brown, S.3    Zhou, L.4    Shaw, M.5    Vella, M.C.6    Cheng, H.7    McNay, E.C.8    Sherwin, R.S.9    McCrimmon, R.J.10
  • 26
    • 79957896666 scopus 로고    scopus 로고
    • Sixteen years and counting: an update on leptin in energy balance
    • Gautron L., Elmquist J.K. Sixteen years and counting: an update on leptin in energy balance. J. Clin. Investig. 2011, 121:2087-2093.
    • (2011) J. Clin. Investig. , vol.121 , pp. 2087-2093
    • Gautron, L.1    Elmquist, J.K.2
  • 27
    • 33749361686 scopus 로고    scopus 로고
    • Can homeostatic circuits learn and remember?
    • Gordon G.R., Bains J.S. Can homeostatic circuits learn and remember?. J. Physiol. 2006, 576:341-347.
    • (2006) J. Physiol. , vol.576 , pp. 341-347
    • Gordon, G.R.1    Bains, J.S.2
  • 30
    • 78049525571 scopus 로고    scopus 로고
    • Corticosterone regulates synaptic input organization of POMC and NPY/AgRP neurons in adult mice
    • Gyengesi E., Liu Z.W., D'Agostino G., Gan G., Horvath T.L., Gao X.B., Diano S. Corticosterone regulates synaptic input organization of POMC and NPY/AgRP neurons in adult mice. Endocrinology 2010, 151:5395-5402.
    • (2010) Endocrinology , vol.151 , pp. 5395-5402
    • Gyengesi, E.1    Liu, Z.W.2    D'Agostino, G.3    Gan, G.4    Horvath, T.L.5    Gao, X.B.6    Diano, S.7
  • 32
    • 39749087530 scopus 로고    scopus 로고
    • SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
    • Han M.K., Song E.K., Guo Y., Ou X., Mantel C., Broxmeyer H.E. SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2008, 2:241-251.
    • (2008) Cell Stem Cell , vol.2 , pp. 241-251
    • Han, M.K.1    Song, E.K.2    Guo, Y.3    Ou, X.4    Mantel, C.5    Broxmeyer, H.E.6
  • 35
    • 85027474023 scopus 로고
    • Hypothalamic lesions and adiposity in the rat
    • Hetherington A.W., Ranson S.W. Hypothalamic lesions and adiposity in the rat. Anat. Rec. 1940, 1-4.
    • (1940) Anat. Rec. , pp. 1-4
    • Hetherington, A.W.1    Ranson, S.W.2
  • 38
    • 17844391500 scopus 로고    scopus 로고
    • The hardship of obesity: a soft-wired hypothalamus
    • Horvath T.L. The hardship of obesity: a soft-wired hypothalamus. Nat. Neurosci. 2005, 8:561-565.
    • (2005) Nat. Neurosci. , vol.8 , pp. 561-565
    • Horvath, T.L.1
  • 40
    • 49349099488 scopus 로고    scopus 로고
    • Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine
    • Jerlhag E. Systemic administration of ghrelin induces conditioned place preference and stimulates accumbal dopamine. Addict. Biol. 2008, 13:358-363.
    • (2008) Addict. Biol. , vol.13 , pp. 358-363
    • Jerlhag, E.1
  • 41
    • 33745834319 scopus 로고    scopus 로고
    • Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
    • Kadowaki T., Yamauchi T., Kubota N., Hara K., Ueki K., Tobe K. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. J. Clin. Investig. 2006, 116:1784-1792.
    • (2006) J. Clin. Investig. , vol.116 , pp. 1784-1792
    • Kadowaki, T.1    Yamauchi, T.2    Kubota, N.3    Hara, K.4    Ueki, K.5    Tobe, K.6
  • 43
    • 0037382853 scopus 로고    scopus 로고
    • Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin
    • Kohno D., Gao H.Z., Muroya S., Kikuyama S., Yada T. Ghrelin directly interacts with neuropeptide-Y-containing neurons in the rat arcuate nucleus: Ca2+ signaling via protein kinase A and N-type channel-dependent mechanisms and cross-talk with leptin and orexin. Diabetes 2003, 52:948-956.
    • (2003) Diabetes , vol.52 , pp. 948-956
    • Kohno, D.1    Gao, H.Z.2    Muroya, S.3    Kikuyama, S.4    Yada, T.5
  • 44
    • 34249829624 scopus 로고    scopus 로고
    • Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway
    • Kohno D., Nakata M., Maekawa F., Fujiwara K., Maejima Y., Kuramochi M., Shimazaki T., Okano H., Onaka T., Yada T. Leptin suppresses ghrelin-induced activation of neuropeptide Y neurons in the arcuate nucleus via phosphatidylinositol 3-kinase- and phosphodiesterase 3-mediated pathway. Endocrinology 2007, 148:2251-2263.
    • (2007) Endocrinology , vol.148 , pp. 2251-2263
    • Kohno, D.1    Nakata, M.2    Maekawa, F.3    Fujiwara, K.4    Maejima, Y.5    Kuramochi, M.6    Shimazaki, T.7    Okano, H.8    Onaka, T.9    Yada, T.10
  • 45
    • 37449021674 scopus 로고    scopus 로고
    • Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons
    • Kohno D., Sone H., Minokoshi Y., Yada T. Ghrelin raises [Ca2+]i via AMPK in hypothalamic arcuate nucleus NPY neurons. Biochem. Biophys. Res. Commun. 2008, 366:388-392.
    • (2008) Biochem. Biophys. Res. Commun. , vol.366 , pp. 388-392
    • Kohno, D.1    Sone, H.2    Minokoshi, Y.3    Yada, T.4
  • 51
    • 27344431720 scopus 로고    scopus 로고
    • NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates
    • Luquet S., Perez F.A., Hnasko T.S., Palmiter R.D. NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science 2005, 310:683-685.
    • (2005) Science , vol.310 , pp. 683-685
    • Luquet, S.1    Perez, F.A.2    Hnasko, T.S.3    Palmiter, R.D.4
  • 52
    • 33846597193 scopus 로고    scopus 로고
    • NPY/AgRP neurons are not essential for feeding responses to glucoprivation
    • Luquet S., Phillips C.T., Palmiter R.D. NPY/AgRP neurons are not essential for feeding responses to glucoprivation. Peptides 2007, 28:214-225.
    • (2007) Peptides , vol.28 , pp. 214-225
    • Luquet, S.1    Phillips, C.T.2    Palmiter, R.D.3
  • 53
    • 79959985242 scopus 로고    scopus 로고
    • Calorie restriction attenuates LPS-induced sickness behavior and shifts hypothalamic signaling pathways to an anti-inflammatory bias
    • MacDonald L., Radler M., Paolini A.G., Kent S. Calorie restriction attenuates LPS-induced sickness behavior and shifts hypothalamic signaling pathways to an anti-inflammatory bias. Am. J. Physiol. 2011, 301:R172-R184.
    • (2011) Am. J. Physiol. , vol.301
    • MacDonald, L.1    Radler, M.2    Paolini, A.G.3    Kent, S.4
  • 55
    • 33745224043 scopus 로고    scopus 로고
    • Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle
    • Martin T.L., Alquier T., Asakura K., Furukawa N., Preitner F., Kahn B.B. Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. J. Biol. Chem. 2006, 281:18933-18941.
    • (2006) J. Biol. Chem. , vol.281 , pp. 18933-18941
    • Martin, T.L.1    Alquier, T.2    Asakura, K.3    Furukawa, N.4    Preitner, F.5    Kahn, B.B.6
  • 56
    • 74949110443 scopus 로고    scopus 로고
    • Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activation
    • Mayer C.M., Belsham D.D. Palmitate attenuates insulin signaling and induces endoplasmic reticulum stress and apoptosis in hypothalamic neurons: rescue of resistance and apoptosis through adenosine 5' monophosphate-activated protein kinase activation. Endocrinology 2010, 151:576-585.
    • (2010) Endocrinology , vol.151 , pp. 576-585
    • Mayer, C.M.1    Belsham, D.D.2
  • 59
    • 58149339613 scopus 로고    scopus 로고
    • Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival
    • Narbonne P., Roy R. Caenorhabditis elegans dauers need LKB1/AMPK to ration lipid reserves and ensure long-term survival. Nature 2009, 457:210-214.
    • (2009) Nature , vol.457 , pp. 210-214
    • Narbonne, P.1    Roy, R.2
  • 61
    • 79960217946 scopus 로고    scopus 로고
    • Long-term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic gluconeogenesis without changing food intake
    • Park S., Kim D.S., Kwon D.Y., Yang H.J. Long-term central infusion of adiponectin improves energy and glucose homeostasis by decreasing fat storage and suppressing hepatic gluconeogenesis without changing food intake. J. Neuroendocrinol. 2011, 23:687-698.
    • (2011) J. Neuroendocrinol. , vol.23 , pp. 687-698
    • Park, S.1    Kim, D.S.2    Kwon, D.Y.3    Yang, H.J.4
  • 66
    • 33747356154 scopus 로고    scopus 로고
    • Adipose tissue: from lipid storage compartment to endocrine organ
    • Scherer P.E. Adipose tissue: from lipid storage compartment to endocrine organ. Diabetes 2006, 55:1537-1545.
    • (2006) Diabetes , vol.55 , pp. 1537-1545
    • Scherer, P.E.1
  • 68
    • 67650914230 scopus 로고    scopus 로고
    • AMPK in health and disease
    • Steinberg G.R., Kemp B.E. AMPK in health and disease. Physiol. Rev. 2009, 89:1025-1078.
    • (2009) Physiol. Rev. , vol.89 , pp. 1025-1078
    • Steinberg, G.R.1    Kemp, B.E.2
  • 70
    • 27744457512 scopus 로고    scopus 로고
    • Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting
    • Sternson S.M., Shepherd G.M., Friedman J.M. Topographic mapping of VMH → arcuate nucleus microcircuits and their reorganization by fasting. Nat. Neurosci. 2005, 8:1356-1363.
    • (2005) Nat. Neurosci. , vol.8 , pp. 1356-1363
    • Sternson, S.M.1    Shepherd, G.M.2    Friedman, J.M.3
  • 71
    • 67650503645 scopus 로고    scopus 로고
    • Enhanced expressions of mRNA for neuropeptide Y and interleukin 1 beta in hypothalamic arcuate nuclei during adjuvant arthritis-induced anorexia in Lewis rats
    • Stofkova A., Haluzik M., Zelezna B., Kiss A., Skurlova M., Lacinova Z., Jurcovicova J. Enhanced expressions of mRNA for neuropeptide Y and interleukin 1 beta in hypothalamic arcuate nuclei during adjuvant arthritis-induced anorexia in Lewis rats. NeuroImmunoModulation 2009, 16:377-384.
    • (2009) NeuroImmunoModulation , vol.16 , pp. 377-384
    • Stofkova, A.1    Haluzik, M.2    Zelezna, B.3    Kiss, A.4    Skurlova, M.5    Lacinova, Z.6    Jurcovicova, J.7
  • 73
    • 0034687376 scopus 로고    scopus 로고
    • Ghrelin induces adiposity in rodents
    • Tschop M., Smiley D.L., Heiman M.L. Ghrelin induces adiposity in rodents. Nature 2000, 407:908-913.
    • (2000) Nature , vol.407 , pp. 908-913
    • Tschop, M.1    Smiley, D.L.2    Heiman, M.L.3
  • 76
    • 84876125944 scopus 로고    scopus 로고
    • Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression
    • Watterson K.R., Bestow D., Gallagher J., Hamilton D.L., Ashford F.B., Meakin P.J., Ashford M.L. Anorexigenic and orexigenic hormone modulation of mammalian target of rapamycin complex 1 activity and the regulation of hypothalamic agouti-related protein mRNA expression. Neuro-Signals 2012.
    • (2012) Neuro-Signals
    • Watterson, K.R.1    Bestow, D.2    Gallagher, J.3    Hamilton, D.L.4    Ashford, F.B.5    Meakin, P.J.6    Ashford, M.L.7
  • 77
    • 78449267024 scopus 로고    scopus 로고
    • Globular adiponectin regulates energy homeostasis through AMP-activated protein kinase-acetyl-CoA carboxylase (AMPK/ACC) pathway in the hypothalamus
    • Wen J.P., Liu C.E., Hu Y.T., Chen G., Lin L.X. Globular adiponectin regulates energy homeostasis through AMP-activated protein kinase-acetyl-CoA carboxylase (AMPK/ACC) pathway in the hypothalamus. Mol. Cell. Biochem. 2010, 344:109-115.
    • (2010) Mol. Cell. Biochem. , vol.344 , pp. 109-115
    • Wen, J.P.1    Liu, C.E.2    Hu, Y.T.3    Chen, G.4    Lin, L.X.5
  • 78
    • 0032744366 scopus 로고    scopus 로고
    • Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat
    • Willesen M.G., Kristensen P., Romer J. Co-localization of growth hormone secretagogue receptor and NPY mRNA in the arcuate nucleus of the rat. Neuroendocrinology 1999, 70:306-316.
    • (1999) Neuroendocrinology , vol.70 , pp. 306-316
    • Willesen, M.G.1    Kristensen, P.2    Romer, J.3
  • 79
    • 77249146406 scopus 로고    scopus 로고
    • Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons
    • Williams K.W., Margatho L.O., Lee C.E., Choi M., Lee S., Scott M.M., Elias C.F., Elmquist J.K. Segregation of acute leptin and insulin effects in distinct populations of arcuate proopiomelanocortin neurons. J. Neurosci. 2010, 30:2472-2479.
    • (2010) J. Neurosci. , vol.30 , pp. 2472-2479
    • Williams, K.W.1    Margatho, L.O.2    Lee, C.E.3    Choi, M.4    Lee, S.5    Scott, M.M.6    Elias, C.F.7    Elmquist, J.K.8
  • 81
    • 80052922112 scopus 로고    scopus 로고
    • Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
    • Yang Y., Atasoy D., Su H.H., Sternson S.M. Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop. Cell 2011, 146:992-1003.
    • (2011) Cell , vol.146 , pp. 992-1003
    • Yang, Y.1    Atasoy, D.2    Su, H.H.3    Sternson, S.M.4
  • 83
    • 79551512119 scopus 로고    scopus 로고
    • Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits
    • Zhang Y., Kerman I.A., Laque A., Nguyen P., Faouzi M., Louis G.W., Jones J.C., Rhodes C., Munzberg H. Leptin-receptor-expressing neurons in the dorsomedial hypothalamus and median preoptic area regulate sympathetic brown adipose tissue circuits. J. Neurosci. 2011, 31:1873-1884.
    • (2011) J. Neurosci. , vol.31 , pp. 1873-1884
    • Zhang, Y.1    Kerman, I.A.2    Laque, A.3    Nguyen, P.4    Faouzi, M.5    Louis, G.W.6    Jones, J.C.7    Rhodes, C.8    Munzberg, H.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.