-
1
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman, J.M. & Halaas, J.L. Leptin and the regulation of body weight in mammals. Nature 395, 763-770 (1998).
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
2
-
-
0033082380
-
From lesions to leptin: Hypothalamic control of food intake and body weight
-
Elmquist, J.K., Elias, C.F. & Saper, C.B. From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 22, 221-232 (1999).
-
(1999)
Neuron
, vol.22
, pp. 221-232
-
-
Elmquist, J.K.1
Elias, C.F.2
Saper, C.B.3
-
3
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra, S.P. et al. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 20, 68-100 (1999).
-
(1999)
Endocr. Rev.
, vol.20
, pp. 68-100
-
-
Kalra, S.P.1
-
4
-
-
0034611732
-
Central nervous system control of food intake
-
Schwartz, M.W., Woods, S.C., Porte, D. Jr, Seeley, R.J. & Baskin, D.G. Central nervous system control of food intake. Nature 404, 661-671 (2000).
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
5
-
-
0002428695
-
Sir. Cutaneous sensation
-
(ed. Sharpey-Schaefer, E.A.) Pentland, Edinburgh
-
Sherrington, C. Sir. Cutaneous sensation, in Textbook of Physiology (ed. Sharpey-Schaefer, E.A.) 920-1001 (Pentland, Edinburgh, 1900).
-
(1900)
Textbook of Physiology
, pp. 920-1001
-
-
Sherrington, C.1
-
8
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y. et al. Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432 (1994).
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
-
9
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas, J.L. et al. Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269, 543-546 (1995).
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
-
10
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter, M.A. et al. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269, 540-543 (1995).
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
-
11
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield, L.A., Smith, F.J., Guisez, Y., Devos, R. & Burn, P. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269, 546-549 (1995).
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
12
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia, L.A. et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 83, 1263-1271 (1995).
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
-
13
-
-
0029895233
-
Localization of leptin receptor mRNA and the long splice variant (0-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization
-
Mercer, J.G. et al. Localization of leptin receptor mRNA and the long splice variant (0-Rb) in mouse hypothalamus and adjacent brain regions by in situ hybridization. FEBS Lett. 387, 113-116 (1996).
-
(1996)
FEBS Lett.
, vol.387
, pp. 113-116
-
-
Mercer, J.G.1
-
14
-
-
0029739970
-
Identification of leptin action in rat hypothalamus
-
Schwartz, M.W., Seeley, R.J., Campfield, L.A., Burn, P. & Baskin, D.G. Identification of leptin action in rat hypothalamus. J. Clin. Invest. 98, 1101-1106 (1996).
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
15
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D. et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141 (1997).
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
-
16
-
-
0030614331
-
Role of melanocortinergic neurons in feeding and the agouti obesity syndrome
-
Fan, W., Boston, B.A., Kesterson, R.A., Hruby, V.J. & Cone, R.D. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome. Nature 385, 165-158 (1997).
-
(1997)
Nature
, vol.385
, pp. 165-1158
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
17
-
-
0017659117
-
Electron microscopic immunohistochemical localization of α-msh in the rat brain
-
Pelletier, G. & Dube, D. Electron microscopic immunohistochemical localization of α-msh in the rat brain. Am. J. Anat. 150, 201-205 (1977).
-
(1977)
Am. J. Anat.
, vol.150
, pp. 201-205
-
-
Pelletier, G.1
Dube, D.2
-
18
-
-
85042693485
-
Melanocortin receptors in luptin effects
-
Seeley, R.J. et al. Melanocortin receptors in luptin effects. Nature 390, 349 (1997).
-
(1997)
Nature
, vol.390
, pp. 349
-
-
Seeley, R.J.1
-
19
-
-
0030764741
-
Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
-
Ollmann, M. M. et al. Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278, 135-138 (1997).
-
(1997)
Science
, vol.278
, pp. 135-138
-
-
Ollmann, M.M.1
-
20
-
-
0032130554
-
Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
-
Hahn, T.M., Breininger, J.F., Baskin, D.G. & Schwartz, M.W. Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat. Neurosci. 1, 271-272 (1998).
-
(1998)
Nat. Neurosci.
, vol.1
, pp. 271-272
-
-
Hahn, T.M.1
Breininger, J.F.2
Baskin, D.G.3
Schwartz, M.W.4
-
21
-
-
0033180532
-
Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area
-
Elias, C.F. et al. Leptin differentially regulates NPY and POMC neurons projecting to the lateral hypothalamic area. Neuron 23, 775-786 (1999).
-
(1999)
Neuron
, vol.23
, pp. 775-786
-
-
Elias, C.F.1
-
22
-
-
0035942777
-
Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus
-
Cowley, M.A. et al. Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus. Nature 411, 480-484 (2001).
-
(2001)
Nature
, vol.411
, pp. 480-484
-
-
Cowley, M.A.1
-
23
-
-
0026463547
-
Neuropeptide-Y innervation of beta-endorphin-containing cells in the rat mediobasal hypothalamus: A light and electron microscopic double immunostaining analysis
-
Horvath, T.L., Naftolin, F., Kalra, S.P. & Leranth, C. Neuropeptide-Y innervation of beta-endorphin-containing cells in the rat mediobasal hypothalamus: a light and electron microscopic double immunostaining analysis. Endocrinology 131, 2461-2467 (1992).
-
(1992)
Endocrinology
, vol.131
, pp. 2461-2467
-
-
Horvath, T.L.1
Naftolin, F.2
Kalra, S.P.3
Leranth, C.4
-
24
-
-
1842529267
-
Rapid re-wiring of arcuate nucleus feeding circuits by leptin
-
Pinto, S. et al. Rapid re-wiring of arcuate nucleus feeding circuits by leptin. Science 304, 110-115 (2004).
-
(2004)
Science
, vol.304
, pp. 110-115
-
-
Pinto, S.1
-
25
-
-
0242583963
-
Hypothalamic melanocortin neurons integrate signals of energy state
-
Cowley, M.A. Hypothalamic melanocortin neurons integrate signals of energy state. Eur. J. Pharmacol. 480, 3-11 (2003).
-
(2003)
Eur. J. Pharmacol.
, vol.480
, pp. 3-11
-
-
Cowley, M.A.1
-
26
-
-
0032443807
-
The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice
-
Broberger, C., Johansen, J., Johansson, C., Schalling, M. & Hokfelt, T. The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice. Proc. Natl. Acad. Sci. USA 95, 15043-15048 (1998).
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 15043-15048
-
-
Broberger, C.1
Johansen, J.2
Johansson, C.3
Schalling, M.4
Hokfelt, T.5
-
27
-
-
0021956581
-
Distribution of the pro-opiomelanocortin derived peptides, adrenocorticotrope hormone, α-melanocyte-stimulating hormone and β-endorphin (ACTH, α-MSH, β-END) in the rat hypothalamus
-
Mezey, E. et al. Distribution of the pro-opiomelanocortin derived peptides, adrenocorticotrope hormone, α-melanocyte-stimulating hormone and β-endorphin (ACTH, α-MSH, β-END) in the rat hypothalamus. Brain Res. 328, 341-347 (1985).
-
(1985)
Brain Res.
, vol.328
, pp. 341-347
-
-
Mezey, E.1
-
28
-
-
0032436307
-
Leptin activates hypothalamic CART neurons projecting to the spiral cord
-
Elias, C.F. et al. Leptin activates hypothalamic CART neurons projecting to the spiral cord. Neuron 21, 1375-1385 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1375-1385
-
-
Elias, C.F.1
-
29
-
-
13344279395
-
A role for melanin-concentrating hormone in the central regulation of feeding behavior
-
Qu, D. et al. A role for melanin-concentrating hormone in the central regulation of feeding behavior. Nature 380, 243-247 (1996).
-
(1996)
Nature
, vol.380
, pp. 243-247
-
-
Qu, D.1
-
30
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai, T. et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92, 573-585 (1998).
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
-
31
-
-
0021327984
-
Evidence for structural plasticity in the supraoptic nucleus of the rat hypothalamus in relation to gestation and lactation
-
Theodosis, D.T. & Poulain, D.A. Evidence for structural plasticity in the supraoptic nucleus of the rat hypothalamus in relation to gestation and lactation. Neuroscience 11, 183-193 (1984).
-
(1984)
Neuroscience
, vol.11
, pp. 183-193
-
-
Theodosis, D.T.1
Poulain, D.A.2
-
32
-
-
0022653095
-
Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats
-
Garcia-Segura, L.M., Baetens, D. & Naftolin, F. Synaptic remodelling in arcuate nucleus after injection of estradiol valerate in adult female rats. Brain Res. 366, 131-136 (1986).
-
(1986)
Brain Res.
, vol.366
, pp. 131-136
-
-
Garcia-Segura, L.M.1
Baetens, D.2
Naftolin, F.3
-
33
-
-
17844393711
-
Input organization and plasticity of hypocretin neurons: Possible clues for obesity's association with insomnia
-
Horvath, T.L. & Gao, X.B. Input organization and plasticity of hypocretin neurons: possible clues for obesity's association with insomnia. Cell Metabolism 1, 279-286 (2005).
-
(2005)
Cell Metabolism
, vol.1
, pp. 279-286
-
-
Horvath, T.L.1
Gao, X.B.2
-
34
-
-
3543029244
-
The floating blueprint of hypothalamic feeding circuits
-
Horvath, T.L. & Diano, S. The floating blueprint of hypothalamic feeding circuits. Nat. Rev. Neurosci. 5, 662-667 (2004).
-
(2004)
Nat. Rev. Neurosci.
, vol.5
, pp. 662-667
-
-
Horvath, T.L.1
Diano, S.2
-
35
-
-
0036162117
-
The neuroanatomical axis for control of energy balance
-
Grill, H.J. & Kaplan, J.M. The neuroanatomical axis for control of energy balance. Front. Neuroendocrinol. 23, 2-40 (2002).
-
(2002)
Front. Neuroendocrinol.
, vol.23
, pp. 2-40
-
-
Grill, H.J.1
Kaplan, J.M.2
-
36
-
-
6344267074
-
Rhythms of ghrelin, leptin, and sleep in rats: Effects of the normal diurnal cycle, restricted feeding, and sleep deprivation
-
Bodosi, B. et al. Rhythms of ghrelin, leptin, and sleep in rats: effects of the normal diurnal cycle, restricted feeding, and sleep deprivation. Am. J. Physiol. Regul. Integr. Comp. Physiol. 287, R1071-R1079 (2004).
-
(2004)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.287
-
-
Bodosi, B.1
-
37
-
-
1842536210
-
Trophic action of leptin on hypothalamic neurons that regulate feeding
-
Bouret, S.G., Draper, S.J. & Simerly, R.B. Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304, 108-110 (2004).
-
(2004)
Science
, vol.304
, pp. 108-110
-
-
Bouret, S.G.1
Draper, S.J.2
Simerly, R.B.3
-
38
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
Chemelli, R.M. et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 98, 437-451 (1999).
-
(1999)
Cell
, vol.98
, pp. 437-451
-
-
Chemelli, R.M.1
-
39
-
-
0038521277
-
Hypothalamic orexin neurons regulate arousal according to energy balance in mice
-
Yamanaka, A. Hypothalamic orexin neurons regulate arousal according to energy balance in mice. Neuron 38, 701-713 (2003).
-
(2003)
Neuron
, vol.38
, pp. 701-713
-
-
Yamanaka, A.1
-
40
-
-
0037137682
-
Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system
-
Li, Y., Gao, X.B., Sakurai, T. & van den Pol, A.N. Hypocretin/Orexin excites hypocretin neurons via a local glutamate neuron-A potential mechanism for orchestrating the hypothalamic arousal system. Neuron 36, 1169-1181 (2002).
-
(2002)
Neuron
, vol.36
, pp. 1169-1181
-
-
Li, Y.1
Gao, X.B.2
Sakurai, T.3
Van Den Pol, A.N.4
-
41
-
-
84940018856
-
Introduction to synaptic circuits
-
(ed. Shepherd, G.M.) Oxford Univ. Press, New York
-
Shepherd, G.M. Introduction to synaptic circuits. in The Synaptic Organization of the Brain. (ed. Shepherd, G.M.) 1-38 (Oxford Univ. Press, New York, 2004).
-
(2004)
The Synaptic Organization of the Brain
, pp. 1-38
-
-
Shepherd, G.M.1
-
42
-
-
15744378271
-
Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index
-
published online 7 December 2004 (doi: 10.1371/journal.pmed.0010062)
-
Taheri, S., Lin, L., Austin, D., Young, T., Mignot, E. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med., published online 7 December 2004 (doi: 10.1371/journal.pmed.0010062).
-
PLoS Med.
-
-
Taheri, S.1
Lin, L.2
Austin, D.3
Young, T.4
Mignot, E.5
-
43
-
-
10044287245
-
Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite
-
Spiegel, K., Tasali, E., Penev, P. & Van Cauter, E. Brief communication: Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann. Intern. Med. 141, 846-850 (2004).
-
(2004)
Ann. Intern. Med.
, vol.141
, pp. 846-850
-
-
Spiegel, K.1
Tasali, E.2
Penev, P.3
Van Cauter, E.4
-
44
-
-
10044268602
-
A good night's sleep: Future antidote to the obesity epidemic?
-
Flier, J.S. & Elmquist, J.K. A good night's sleep: future antidote to the obesity epidemic? Ann. Intern. Med. 141, 885-886 (2004).
-
(2004)
Ann. Intern. Med.
, vol.141
, pp. 885-886
-
-
Flier, J.S.1
Elmquist, J.K.2
-
45
-
-
0037547166
-
In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus
-
Pittenger, C. & Kandel, E.R. In search of general mechanisms for long-lasting plasticity: Aplysia and the hippocampus. Phil. Trans. R. Soc. Lond. B 358, 757-763 (2003).
-
(2003)
Phil. Trans. R. Soc. Lond. B
, vol.358
, pp. 757-763
-
-
Pittenger, C.1
Kandel, E.R.2
-
46
-
-
5344241223
-
LTP and LTD: An embarrassment of riches
-
Malenka, R.C. & Bear, M.F. LTP and LTD: an embarrassment of riches. Neuron 44, 5-21 (2004).
-
(2004)
Neuron
, vol.44
, pp. 5-21
-
-
Malenka, R.C.1
Bear, M.F.2
-
47
-
-
12544249267
-
Long-term potentiation and cognitive drug discovery
-
Cooke, S.F. & Bliss, T.V. Long-term potentiation and cognitive drug discovery. Curr. Opin. Investig. Drugs 6, 25-34 (2005).
-
(2005)
Curr. Opin. Investig. Drugs
, vol.6
, pp. 25-34
-
-
Cooke, S.F.1
Bliss, T.V.2
-
48
-
-
0015827314
-
Basic and clinical studies with luteinizing hormone-releasing hormone (LH-RH) and its analogues
-
Schally, A.V. et al. Basic and clinical studies with luteinizing hormone-releasing hormone (LH-RH) and its analogues. J. Reprod. Fertil. Suppl. 20, 119-136 (1973).
-
(1973)
J. Reprod. Fertil. Suppl.
, vol.20
, pp. 119-136
-
-
Schally, A.V.1
-
49
-
-
0027991473
-
GnRH neurons and other cellular and molecular mechanisms for simple mammalian reproductive behaviors
-
Pfaff, D.W. et al. GnRH neurons and other cellular and molecular mechanisms for simple mammalian reproductive behaviors. Recent Prog. Horm. Res. 49, 1-25 (1994).
-
(1994)
Recent Prog. Horm. Res.
, vol.49
, pp. 1-25
-
-
Pfaff, D.W.1
|