Depletion of nuclear histone H2A variants is associated with chronic DNA damage signaling upon drug-evoked senescence of human somatic cells

Aging

Volumn 4, Issue 11, 2012, Pages 823-842

  Lopez, Mary F ^a   Tollervey, James ^b   Krastins, Bryan ^a   Garces, Alejandra ^a   Sarracino, David ^a   Prakash, Amol ^a   Vogelsang, Maryann ^a   Geesman, Glenn ^b   Valderrama, Augusto ^d   Jordan, I King ^c   Lunyak, Victoria V ^b  

^a Thermo Fisher Scientific   (United States)

^b BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^c GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^d University de Libra   (Colombia)

Author keywords

Chromatin; DNA damage; DNA repair; Epigenetics; HCA2 primary fibroblasts; Histone H2A family; LS MS analysis; Quantitative proteomic; Senescence; SRM; H2A.X

Indexed keywords

EID: 84872584428     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100507     Document Type: Article

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