-
1
-
-
64249107059
-
Evidence for cardiomocyte renewal in humans
-
Bergmann O, Bhardwaj RD, Bernard S, Zdunek S, Barnabé-Heider F, Walsh S, Zupicich J, Alkass K, Buchholz BA, Druid H, Jovinge S, Frisén J: Evidence for cardiomocyte renewal in humans. Science 2009; 324: 98-102.
-
(2009)
Science
, vol.324
, pp. 98-102
-
-
Bergmann, O.1
Bhardwaj, R.D.2
Bernard, S.3
Zdunek, S.4
Barnabé-Heider, F.5
Walsh, S.6
Zupicich, J.7
Alkass, K.8
Buchholz, B.A.9
Druid, H.10
Jovinge, S.11
Frisén, J.12
-
2
-
-
34548150187
-
The role of nuclear architecture in genomic instability and aging
-
Oberdoerffer P, Sinclair DA: The role of nuclear architecture in genomic instability and aging. Nat Rev Mol Cell Biol 2007; 8: 692-702.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 692-702
-
-
Oberdoerffer, P.1
Sinclair, D.A.2
-
3
-
-
34447625911
-
Epigenetics and aging: The targets and the marks
-
Fraga MF, Esteller M: Epigenetics and aging: the targets and the marks. Trends Genet 2007; 23: 413-418.
-
(2007)
Trends Genet
, vol.23
, pp. 413-418
-
-
Fraga, M.F.1
Esteller, M.2
-
4
-
-
34548667973
-
Telomere length, stem cells and aging
-
Blasco MA: Telomere length, stem cells and aging. Nat Chem Biol 2007; 3: 640-649.
-
(2007)
Nat Chem Biol
, vol.3
, pp. 640-649
-
-
Ma, B.1
-
5
-
-
34447543913
-
Cellular senescence in cancer and aging
-
Collado M, Blasco MA, Serrano M: Cellular senescence in cancer and aging. Cell 2007; 130: 223-233.
-
(2007)
Cell
, vol.130
, pp. 223-233
-
-
Collado, M.1
Ma, B.2
Serrano, M.3
-
6
-
-
0033953142
-
Somatic mutations and aging: A reevaluation
-
Vijg J: Somatic mutations and aging: a reevaluation. Mutat Res 2000; 447: 117-135.
-
(2000)
Mutat Res
, vol.447
, pp. 117-135
-
-
Vijg, J.1
-
7
-
-
0035964315
-
Does oxidative damage to DNA increase with age?
-
Hamilton ML, Van Remmen H, Drake JA, Yang H, Guo ZM, Kewitt K, Walter CA, Richardson A: Does oxidative damage to DNA increase with age? Proc Natl Acad Sci USA 2001; 98: 10469-10474.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 10469-10474
-
-
Hamilton, M.L.1
Van Remmen, H.2
Drake, J.A.3
Yang, H.4
Guo, Z.M.5
Kewitt, K.6
Walter, C.A.7
Richardson, A.8
-
8
-
-
20044379205
-
Constitutional aneuploidy in the normal human brain
-
Rehen SK, Yung YC, McCreight MP, Kaushal D, Yang AH, Almeida BSV, Kingsbury MA, Cabral KMS, McConnell MJ, Anliker B, Fontanoz M, Chun J: Constitutional aneuploidy in the normal human brain. J Neurosci 2005; 25: 2176-2180.
-
(2005)
J Neurosci
, vol.25
, pp. 2176-2180
-
-
Rehen, S.K.1
Yung, Y.C.2
McCreight, M.P.3
Kaushal, D.4
Yang, A.H.5
Bsv, A.6
Ma, K.7
Kms, C.8
McConnell, M.J.9
Anliker, B.10
Fontanoz, M.11
Chun, J.12
-
10
-
-
32344450824
-
Genomic DNA methylation: The mark and its mediators
-
Klose RJ, Bird AP: Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 2006; 31: 89-97.
-
(2006)
Trends Biochem Sci
, vol.31
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
11
-
-
0036333103
-
Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
-
Hata K, Okano M, Lei H, Li E: Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development 2002; 129: 1983-1993.
-
(2002)
Development
, vol.129
, pp. 1983-1993
-
-
Hata, K.1
Okano, M.2
Lei, H.3
Li, E.4
-
12
-
-
28444456705
-
He histone code at DNA breaks: A guide to repair?
-
Van Attikum H, Gasser SM: The histone code at DNA breaks: a guide to repair? Nat Rev Mol Cell Biol 2005; 6: 757-765.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 757-765
-
-
Van Attikum, H.1
Gasser, S.M.2
-
13
-
-
33845269544
-
Hutchinson-Gilford progeria syndrome: Review of the phenotype
-
Hennekam RC: Hutchinson-Gilford progeria syndrome: review of the phenotype. Am J Med Genet A 2006; 140A:2603-2624.
-
(2006)
Am J Med Genet A
, vol.140 A
, pp. 2603-2624
-
-
Hennekam, R.C.1
-
14
-
-
33745016642
-
Mutant nuclear lamin a leads to progressive alterations of epigenetic control in premature aging
-
Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, Erdos MR, Eriksson M, Goldman AE, Khuon S, Collins FS, Jenuwein T, Goldman RD: Mutant nuclear lamin a leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci USA 2006; 103: 8703-8708.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 8703-8708
-
-
Shumaker, D.K.1
Dechat, T.2
Kohlmaier, A.3
Adam, S.A.4
Bozovsky, M.R.5
Erdos, M.R.6
Eriksson, M.7
Goldman, A.E.8
Khuon, S.9
Collins, F.S.10
Jenuwein, T.11
Goldman, R.D.12
-
15
-
-
15844409553
-
Positional cloning of the Werner's syndrome gene
-
Yu C-E, Oshima J, Fu Y-H, Wijsman EM, Hisama F, Alisch R, Matthews S, Nakura J, Miki T, Ouais S, Martin GM, Mulligan J, Schellenberg GD: Positional cloning of the Werner's syndrome gene. Science 1996; 272: 258-262.
-
(1996)
Science
, vol.272
, pp. 258-262
-
-
Yu, C.-E.1
Oshima, J.2
Fu, Y.-H.3
Wijsman, E.M.4
Hisama, F.5
Alisch, R.6
Matthews, S.7
Nakura, J.8
Miki, T.9
Ouais, S.10
Martin, G.M.11
Mulligan, J.12
Schellenberg, G.D.13
-
16
-
-
0029002103
-
Ataxia telangiectasia: Closer to unraveling the mystery
-
Shiloh Y: Ataxia telangiectasia: closer to unraveling the mystery. Eur J Hum Genet 1995; 3: 116-138.
-
(1995)
Eur J Hum Genet
, vol.3
, pp. 116-138
-
-
Shiloh, Y.1
-
17
-
-
0025123685
-
Mouse satellite DNA is transcribed in senescent cardiac muscle
-
Gaubatz JW, Cutler RG: Mouse satellite DNA is transcribed in senescent cardiac muscle. J Biol Chem 1990; 265: 17753-17758.
-
(1990)
J Biol Chem
, vol.265
, pp. 17753-17758
-
-
Gaubatz, J.W.1
Cutler, R.G.2
-
18
-
-
0347991998
-
Age-associated activation of epigenetically repressed genes in the mouse
-
Bennett-Baker PE, Wilkowski J, Burke DT: Age-associated activation of epigenetically repressed genes in the mouse. Genetics 2003; 165: 2055-2062.
-
(2003)
Genetics
, vol.165
, pp. 2055-2062
-
-
Bennett-Baker, P.E.1
Wilkowski, J.2
Burke, D.T.3
-
19
-
-
0026793281
-
Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts
-
Millis AJ, Hoyle M, McCue HM, Martini H: Differential expression of metalloproteinase and tissue inhibitor of metalloproteinase genes in aged human fibroblasts. Exp Cell Res 1992; 201: 373-379.
-
(1992)
Exp Cell Res
, vol.201
, pp. 373-379
-
-
Millis, A.J.1
Hoyle, M.2
McCue, H.M.3
Martini, H.4
-
20
-
-
0032162220
-
Heterochromatin islands and their dynamic reorganization: A hypothesis for three distinctive features of cellular aging
-
Imai S, Kitano H: Heterochromatin islands and their dynamic reorganization: a hypothesis for three distinctive features of cellular aging. Exp Gerontol 1998; 33: 555-570.
-
(1998)
Exp Gerontol
, vol.33
, pp. 555-570
-
-
Imai, S.1
Kitano, H.2
-
21
-
-
0037667702
-
Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence
-
Narita M, Nunez S, Heard E, Narita M, Lin AW, Hearn SA, Spector DL, Hannon GJ, Lowe SW: Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence. Cell 2003; 113: 703-716.
-
(2003)
Cell
, vol.113
, pp. 703-716
-
-
Narita, M.1
Nunez, S.2
Heard, E.3
Narita, M.4
Lin, A.W.5
Hearn, S.A.6
Spector, D.L.7
Hannon, G.J.8
Lowe, S.W.9
-
22
-
-
0020638422
-
DNA methylation decreases in aging but not in immortal cells
-
Wilson VL, Jones PA: DNA methylation decreases in aging but not in immortal cells. Science 1983; 220: 1055-1057.
-
(1983)
Science
, vol.220
, pp. 1055-1057
-
-
Wilson, V.L.1
Jones, P.A.2
-
23
-
-
0141839825
-
Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts
-
Casillas MA, Lopatina N, Andrews LG, Tollefsbol TO: Transcriptional control of the DNA methyltransferases is altered in aging and neoplastically-transformed human fibroblasts. Mol Cell Biochem 2003; 252: 33-43.
-
(2003)
Mol Cell Biochem
, vol.252
, pp. 33-43
-
-
Ma, C.1
Lopatina, N.2
Andrews, L.G.3
Tollefsbol, T.O.4
-
24
-
-
13944253348
-
Calorie restriction -the SIR2 connection
-
Guarente L, Picard FI: Calorie restriction -the SIR2 connection. Cell 2005; 120: 473-482.
-
(2005)
Cell
, vol.120
, pp. 473-482
-
-
Guarente, L.1
Picard, F.I.2
-
25
-
-
34547875013
-
NAD + -dependent deacetylation of H4 lysine 16 by class III HDACs
-
Vaquero A, Sternglanz R, Reinberg D: NAD + -dependent deacetylation of H4 lysine 16 by class III HDACs. Oncogene 2007; 26: 5505-5520.
-
(2007)
Oncogene
, vol.26
, pp. 5505-5520
-
-
Vaquero, A.1
Sternglanz, R.2
Reinberg, D.3
-
26
-
-
3142740860
-
Calorie restriction promotes mammalian cell survival by inducing the sirt1 deacetylase
-
Cohen HY, Miller C, Bitterman KJ, Wall NR, Hekking B, Kessler B, Howitz KT, Gorospe M, de Cabo R, Sinclair DA: Calorie restriction promotes mammalian cell survival by inducing the sirt1 deacetylase. Science 2004; 305: 390-392.
-
(2004)
Science
, vol.305
, pp. 390-392
-
-
Cohen, H.Y.1
Miller, C.2
Bitterman, K.J.3
Wall, N.R.4
Hekking, B.5
Kessler, B.6
Howitz, K.T.7
Gorospe, M.8
De Cabo, R.9
Sinclair, D.A.10
-
27
-
-
33845399894
-
Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1i
-
Lagouge M, Argmann C, Gerhart-Hines Z, Meziane H, Lerin C, Daussin F, Messadeq N, Milne J, Lambert P, Elliott P, Geny B, Laakso M, Puigserver P, Auwerx J: Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1i. Cell 2006; 127: 1109-1122.
-
(2006)
Cell
, vol.127
, pp. 1109-1122
-
-
Lagouge, M.1
Argmann, C.2
Gerhart-Hines, Z.3
Meziane, H.4
Lerin, C.5
Daussin, F.6
Messadeq, N.7
Milne, J.8
Lambert, P.9
Elliott, P.10
Geny, B.11
Laakso, M.12
Puigserver, P.13
Auwerx, J.14
-
28
-
-
34249281690
-
Stressing the role of FoxO proteins in lifespan and disease
-
Van der Horst A, Burgering BMT: Stressing the role of FoxO proteins in lifespan and disease. Nat Rev Mol Cell Biol 2007; 8: 440-450.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 440-450
-
-
Van Der Horst, A.1
Burgering, B.M.T.2
-
30
-
-
34548153747
-
How stem cells age and why this makes us grow old
-
Sharpless NE, DePinho RA: How stem cells age and why this makes us grow old. Nat Rev Mol Cell Biol 2007; 8: 703-713.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 703-713
-
-
Sharpless, N.E.1
Depinho, R.A.2
-
31
-
-
54949137626
-
Very small embryoniclike stem cells in adult organs and their potential role in rejuvenation of tissues and longevity
-
Ratajczak MZ, Zuba-Surma EK, Shin DM, Ratajczak J, Kucia M: Very small embryoniclike stem cells in adult organs and their potential role in rejuvenation of tissues and longevity. Exp Gerontol 2008; 43: 1009-1017.
-
(2008)
Exp Gerontol
, vol.43
, pp. 1009-1017
-
-
Ratajczak, M.Z.1
Zuba-Surma, E.K.2
Shin, D.M.3
Ratajczak, J.4
Kucia, M.5
-
32
-
-
33646152348
-
A population of very small embryonic-like CXCR4 + SSEA-1 + Oct-4 + stem cells identified in adult bone marrow
-
Kucia M, Reca R, Campbell FR, Zuba-Surma E, Majka M, Ratajczak J, Ratajczak MZ: A population of very small embryonic-like CXCR4 + SSEA-1 + Oct-4 + stem cells identified in adult bone marrow. Leukemia 2006; 20: 857-869.
-
(2006)
Leukemia
, vol.20
, pp. 857-869
-
-
Kucia, M.1
Reca, R.2
Campbell, F.R.3
Zuba-Surma, E.4
Majka, M.5
Ratajczak, J.6
Ratajczak, M.Z.7
-
34
-
-
33846487365
-
Morphological and molecular characterization of novel population of CXCR4 + SSEA-4 + Oct-4 + very small embryonic-like cells purified from human cord blood: Preliminary report
-
Kucia M, Halasa M, Wysoczynski M, Baskiewicz-Masiuk M, Moldenhawer S, Zuba-Surma E, Czajka R, Wojakowski W, Machalinski B, Ratajczak MZ: Morphological and molecular characterization of novel population of CXCR4 + SSEA-4 + Oct-4 + very small embryonic-like cells purified from human cord blood: preliminary report. Leukemia 2006; 21: 297-303.
-
(2006)
Leukemia
, vol.21
, pp. 297-303
-
-
Kucia, M.1
Halasa, M.2
Wysoczynski, M.3
Baskiewicz-Masiuk, M.4
Moldenhawer, S.5
Zuba-Surma, E.6
Czajka, R.7
Wojakowski, W.8
MacHalinski, B.9
Ratajczak, M.Z.10
-
35
-
-
57849169472
-
Mobilization of bone marrow-derived Oct-4 + SSEA-4 + very small embryonic-like stem cells in patients with acute myocardial infarction
-
Wojakowski W, Tendera M, Kucia M, Zuba-Surma E, Paczkowska E, Ciosek J, Halasa M, Król M, Kazmierski M, Buszman P, Ochala A, Ratajczak J, Machalinski B, Ratajczak MZ: Mobilization of bone marrow-derived Oct-4 + SSEA-4 + very small embryonic-like stem cells in patients with acute myocardial infarction. J Am Coll Cardiol 2009; 53: 1-9.
-
(2009)
J Am Coll Cardiol
, vol.53
, pp. 1-9
-
-
Wojakowski, W.1
Tendera, M.2
Kucia, M.3
Zuba-Surma, E.4
Paczkowska, E.5
Ciosek, J.6
Halasa, M.7
Król, M.8
Kazmierski, M.9
Buszman, P.10
Ochala, A.11
Ratajczak, J.12
MacHalinski, B.13
Ratajczak, M.Z.14
-
36
-
-
65249152405
-
Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke
-
Paczkowska E, Kucia M, Koziarska D, Halasa M, Safranow K, Masiuk M, Karbicka A, Nowik M, Nowacki P, Ratajczak MZ, Machalinski B: Clinical evidence that very small embryonic-like stem cells are mobilized into peripheral blood in patients after stroke. Stroke 2009; 40: 1237-1244.
-
(2009)
Stroke
, vol.40
, pp. 1237-1244
-
-
Paczkowska, E.1
Kucia, M.2
Koziarska, D.3
Halasa, M.4
Safranow, K.5
Masiuk, M.6
Karbicka, A.7
Nowik, M.8
Nowacki, P.9
Ratajczak, M.Z.10
MacHalinski, B.11
-
37
-
-
70450260628
-
Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct-4 + very small embryonic-like stem cells
-
Shin DM, Zuba-Surma EK, Wu W, Ratajczak J, Wysoczynski M, Ratajczak MZ, Kucia M: Novel epigenetic mechanisms that control pluripotency and quiescence of adult bone marrow-derived Oct-4 + very small embryonic-like stem cells. Leukemia 2009; 23: 2042-2051.
-
(2009)
Leukemia
, vol.23
, pp. 2042-2051
-
-
Shin, D.M.1
Zuba-Surma, E.K.2
Wu, W.3
Ratajczak, J.4
Wysoczynski, M.5
Ratajczak, M.Z.6
Kucia, M.7
-
38
-
-
0035234557
-
Genomic imprinting: Parental influence on the genome
-
Reik W, Walter J: Genomic imprinting: parental influence on the genome. Nat Rev Genet 2001; 2: 21-32.
-
(2001)
Nat Rev Genet
, vol.2
, pp. 21-32
-
-
Reik, W.1
Walter, J.2
-
39
-
-
7144262409
-
Imprinted gene in postnatal growth role
-
Itier JM, Tremp GL, Leonard JF, Multon MC, Ret G, Schweighoffer F, Tocque B, Bluet-Pajot MT, Cormier V, Dautry F: Imprinted gene in postnatal growth role. Nature 1998; 393: 125-126.
-
(1998)
Nature
, vol.393
, pp. 125-126
-
-
Itier, J.M.1
Tremp, G.L.2
Leonard, J.F.3
Multon, M.C.4
Ret, G.5
Schweighoffer, F.6
Tocque, B.7
Bluet-Pajot, M.T.8
Cormier, V.9
Dautry, F.10
-
40
-
-
0038275831
-
Ras-GRF1 signaling is required for normal -cell development and glucose homeostasis
-
Font de Mora J, Esteban LM, Burks DJ, Nunez A, Garces C, Garcia-Barrado MJ, Iglesias-Osma MC, Moratinos J, Ward JM, Santos E: Ras-GRF1 signaling is required for normal -cell development and glucose homeostasis. EMBO J 2003; 22: 3039-3049.
-
(2003)
EMBO J
, vol.22
, pp. 3039-3049
-
-
Font De Mora, J.1
Esteban, L.M.2
Burks, D.J.3
Nunez, A.4
Garces, C.5
Garcia-Barrado, M.J.6
Iglesias-Osma, M.C.7
Moratinos, J.8
Ward, J.M.9
Santos, E.10
|