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Volumn 8, Issue 1, 2012, Pages

Heterochromatin formation promotes longevity and represses ribosomal RNA synthesis

Author keywords

[No Author keywords available]

Indexed keywords

RIBOSOME DNA; RIBOSOME RNA; CIRCULAR DNA; DROSOPHILA PROTEIN; HETEROCHROMATIN SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP 1; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; HOPSCOTCH PROTEIN, DROSOPHILA; JANUS KINASE; NONHISTONE PROTEIN; STAT PROTEIN; TRANSCRIPTION FACTOR;

EID: 84857477619     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002473     Document Type: Article
Times cited : (224)

References (52)
  • 1
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D, (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11: 298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 2
    • 0031916984 scopus 로고    scopus 로고
    • The free radical theory of aging matures
    • Beckman KB, Ames BN, (1998) The free radical theory of aging matures. Physiol Rev 78: 547-581.
    • (1998) Physiol Rev , vol.78 , pp. 547-581
    • Beckman, K.B.1    Ames, B.N.2
  • 3
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence: implications for in vivo aging and tumor suppression
    • Smith JR, Pereira-Smith OM, (1996) Replicative senescence: implications for in vivo aging and tumor suppression. Science 273: 63-67.
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 4
    • 27144446633 scopus 로고    scopus 로고
    • The molecular and genetic control of leaf senescence and longevity in Arabidopsis
    • Lim PO, Nam HG, (2005) The molecular and genetic control of leaf senescence and longevity in Arabidopsis. Curr Top Dev Biol 67: 49-83.
    • (2005) Curr Top Dev Biol , vol.67 , pp. 49-83
    • Lim, P.O.1    Nam, H.G.2
  • 5
    • 0030759780 scopus 로고    scopus 로고
    • The heterochromatin loss model of aging
    • Villeponteau B, (1997) The heterochromatin loss model of aging. Exp Gerontol 32: 383-394.
    • (1997) Exp Gerontol , vol.32 , pp. 383-394
    • Villeponteau, B.1
  • 6
    • 0025787643 scopus 로고
    • Telomere loss: mitotic clock or genetic time bomb?
    • Harley CB, (1991) Telomere loss: mitotic clock or genetic time bomb? Mutat Res 256: 271-282.
    • (1991) Mutat Res , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 8
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: insights from long-lived mutants
    • Kenyon C, (2005) The plasticity of aging: insights from long-lived mutants. Cell 120: 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 9
    • 34247140294 scopus 로고    scopus 로고
    • Role of insulin-like signalling in Drosophila lifespan
    • Giannakou ME, Partridge L, (2007) Role of insulin-like signalling in Drosophila lifespan. Trends Biochem Sci 32: 180-188.
    • (2007) Trends Biochem Sci , vol.32 , pp. 180-188
    • Giannakou, M.E.1    Partridge, L.2
  • 10
    • 50649101095 scopus 로고    scopus 로고
    • Puzzles, promises and a cure for ageing
    • Vijg J, Campisi J, (2008) Puzzles, promises and a cure for ageing. Nature 454: 1065-1071.
    • (2008) Nature , vol.454 , pp. 1065-1071
    • Vijg, J.1    Campisi, J.2
  • 11
    • 43049162647 scopus 로고    scopus 로고
    • Aging by epigenetics-a consequence of chromatin damage?
    • Sedivy JM, Banumathy G, Adams PD, (2008) Aging by epigenetics-a consequence of chromatin damage? Exp Cell Res 314: 1909-1917.
    • (2008) Exp Cell Res , vol.314 , pp. 1909-1917
    • Sedivy, J.M.1    Banumathy, G.2    Adams, P.D.3
  • 12
    • 34447543913 scopus 로고    scopus 로고
    • Cellular senescence in cancer and aging
    • Collado M, Blasco MA, Serrano M, (2007) Cellular senescence in cancer and aging. Cell 130: 223-233.
    • (2007) Cell , vol.130 , pp. 223-233
    • Collado, M.1    Blasco, M.A.2    Serrano, M.3
  • 13
    • 33846090789 scopus 로고    scopus 로고
    • Accumulation of senescent cells in mitotic tissue of aging primates
    • Jeyapalan JC, Ferreira M, Sedivy JM, Herbig U, (2007) Accumulation of senescent cells in mitotic tissue of aging primates. Mech Ageing Dev 128: 36-44.
    • (2007) Mech Ageing Dev , vol.128 , pp. 36-44
    • Jeyapalan, J.C.1    Ferreira, M.2    Sedivy, J.M.3    Herbig, U.4
  • 15
    • 33646745137 scopus 로고    scopus 로고
    • Lamin A-dependent nuclear defects in human aging
    • Scaffidi P, Misteli T, (2006) Lamin A-dependent nuclear defects in human aging. Science 312: 1059-1063.
    • (2006) Science , vol.312 , pp. 1059-1063
    • Scaffidi, P.1    Misteli, T.2
  • 16
    • 33745016642 scopus 로고    scopus 로고
    • Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging
    • Shumaker DK, Dechat T, Kohlmaier A, Adam SA, Bozovsky MR, et al. (2006) Mutant nuclear lamin A leads to progressive alterations of epigenetic control in premature aging. Proc Natl Acad Sci U S A 103: 8703-8708.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 8703-8708
    • Shumaker, D.K.1    Dechat, T.2    Kohlmaier, A.3    Adam, S.A.4    Bozovsky, M.R.5
  • 18
    • 33845755946 scopus 로고    scopus 로고
    • Heterochromatin revisited
    • Grewal SI, Jia S, (2007) Heterochromatin revisited. Nat Rev Genet 8: 35-46.
    • (2007) Nat Rev Genet , vol.8 , pp. 35-46
    • Grewal, S.I.1    Jia, S.2
  • 19
    • 79960073028 scopus 로고    scopus 로고
    • Unphosphorylated STAT and heterochromatin protect genome stability
    • Yan SJ, Lim SJ, Shi S, Dutta P, Li WX, (2010) Unphosphorylated STAT and heterochromatin protect genome stability. FASEB J.
    • (2010) FASEB J
    • Yan, S.J.1    Lim, S.J.2    Shi, S.3    Dutta, P.4    Li, W.X.5
  • 20
    • 33845866637 scopus 로고    scopus 로고
    • H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability
    • Peng JC, Karpen GH, (2007) H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat Cell Biol 9: 25-35.
    • (2007) Nat Cell Biol , vol.9 , pp. 25-35
    • Peng, J.C.1    Karpen, G.H.2
  • 21
    • 0031459980 scopus 로고    scopus 로고
    • Extrachromosomal rDNA circles-a cause of aging in yeast
    • Sinclair DA, Guarente L, (1997) Extrachromosomal rDNA circles-a cause of aging in yeast. Cell 91: 1033-1042.
    • (1997) Cell , vol.91 , pp. 1033-1042
    • Sinclair, D.A.1    Guarente, L.2
  • 22
    • 0030820491 scopus 로고    scopus 로고
    • Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants
    • Sinclair DA, Mills K, Guarente L, (1997) Accelerated aging and nucleolar fragmentation in yeast sgs1 mutants. Science 277: 1313-1316.
    • (1997) Science , vol.277 , pp. 1313-1316
    • Sinclair, D.A.1    Mills, K.2    Guarente, L.3
  • 23
    • 0026632337 scopus 로고
    • The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation
    • Eissenberg JC, Morris GD, Reuter G, Hartnett T, (1992) The heterochromatin-associated protein HP-1 is an essential protein in Drosophila with dosage-dependent effects on position-effect variegation. Genetics 131: 345-352.
    • (1992) Genetics , vol.131 , pp. 345-352
    • Eissenberg, J.C.1    Morris, G.D.2    Reuter, G.3    Hartnett, T.4
  • 24
    • 0036532235 scopus 로고    scopus 로고
    • Heterochromatin: new possibilities for the inheritance of structure
    • Grewal SI, Elgin SC, (2002) Heterochromatin: new possibilities for the inheritance of structure. Curr Opin Genet Dev 12: 178-187.
    • (2002) Curr Opin Genet Dev , vol.12 , pp. 178-187
    • Grewal, S.I.1    Elgin, S.C.2
  • 25
    • 10044244766 scopus 로고    scopus 로고
    • Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila
    • Ebert A, Schotta G, Lein S, Kubicek S, Krauss V, et al. (2004) Su(var) genes regulate the balance between euchromatin and heterochromatin in Drosophila. Genes Dev 18: 2973-2983.
    • (2004) Genes Dev , vol.18 , pp. 2973-2983
    • Ebert, A.1    Schotta, G.2    Lein, S.3    Kubicek, S.4    Krauss, V.5
  • 26
    • 43149084600 scopus 로고    scopus 로고
    • Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability
    • Shi S, Larson K, Guo D, Lim SJ, Dutta P, et al. (2008) Drosophila STAT is required for directly maintaining HP1 localization and heterochromatin stability. Nat Cell Biol 10: 489-496.
    • (2008) Nat Cell Biol , vol.10 , pp. 489-496
    • Shi, S.1    Larson, K.2    Guo, D.3    Lim, S.J.4    Dutta, P.5
  • 27
    • 33748308794 scopus 로고    scopus 로고
    • JAK signaling globally counteracts heterochromatic gene silencing
    • Shi S, Calhoun HC, Xia F, Li J, Le L, et al. (2006) JAK signaling globally counteracts heterochromatic gene silencing. Nat Genet 38: 1071-1076.
    • (2006) Nat Genet , vol.38 , pp. 1071-1076
    • Shi, S.1    Calhoun, H.C.2    Xia, F.3    Li, J.4    Le, L.5
  • 28
    • 33746826011 scopus 로고    scopus 로고
    • JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions
    • Arbouzova NI, Zeidler MP, (2006) JAK/STAT signalling in Drosophila: insights into conserved regulatory and cellular functions. Development 133: 2605-2616.
    • (2006) Development , vol.133 , pp. 2605-2616
    • Arbouzova, N.I.1    Zeidler, M.P.2
  • 29
    • 0036899655 scopus 로고    scopus 로고
    • The Jak/STAT pathway in model organisms. Emerging roles in cell movement
    • Hou SX, Zheng Z, Chen X, Perrimon N, (2002) The Jak/STAT pathway in model organisms. Emerging roles in cell movement. Dev Cell 3: 765-778.
    • (2002) Dev Cell , vol.3 , pp. 765-778
    • Hou, S.X.1    Zheng, Z.2    Chen, X.3    Perrimon, N.4
  • 30
    • 54049101441 scopus 로고    scopus 로고
    • Canonical and non-canonical JAK-STAT signaling
    • Li WX, (2008) Canonical and non-canonical JAK-STAT signaling. Trends Cell Biol 18: 545-551.
    • (2008) Trends Cell Biol , vol.18 , pp. 545-551
    • Li, W.X.1
  • 31
    • 23844503747 scopus 로고    scopus 로고
    • Drosophila longevity is not affected by heterochromatin-mediated gene silencing
    • Frankel S, Rogina B, (2005) Drosophila longevity is not affected by heterochromatin-mediated gene silencing. Aging Cell 4: 53-56.
    • (2005) Aging Cell , vol.4 , pp. 53-56
    • Frankel, S.1    Rogina, B.2
  • 32
    • 0026554701 scopus 로고
    • A cytogenetic and genetic characterization of a group of closely linked second chromosome mutations that suppress position-effect variegation in Drosophila melanogaster
    • Sinclair DA, Ruddell AA, Brock JK, Clegg NJ, Lloyd VK, et al. (1992) A cytogenetic and genetic characterization of a group of closely linked second chromosome mutations that suppress position-effect variegation in Drosophila melanogaster. Genetics 130: 333-344.
    • (1992) Genetics , vol.130 , pp. 333-344
    • Sinclair, D.A.1    Ruddell, A.A.2    Brock, J.K.3    Clegg, N.J.4    Lloyd, V.K.5
  • 33
    • 34848905626 scopus 로고    scopus 로고
    • Evidence for Transgenerational Transmission of Epigenetic Tumor Susceptibility in Drosophila
    • doi:10.1371/journal.pgen.0030151
    • Xing Y, Shi S, Le L, Lee CA, Silver-Morse L, et al. (2007) Evidence for Transgenerational Transmission of Epigenetic Tumor Susceptibility in Drosophila. PLoS Genet 3: e151 doi:10.1371/journal.pgen.0030151.
    • (2007) PLoS Genet , vol.3
    • Xing, Y.1    Shi, S.2    Le, L.3    Lee, C.A.4    Silver-Morse, L.5
  • 34
    • 34247641746 scopus 로고    scopus 로고
    • Modifiers of epigenetic reprogramming show paternal effects in the mouse
    • Chong S, Vickaryous N, Ashe A, Zamudio N, Youngson N, et al. (2007) Modifiers of epigenetic reprogramming show paternal effects in the mouse. Nat Genet 39: 614-622.
    • (2007) Nat Genet , vol.39 , pp. 614-622
    • Chong, S.1    Vickaryous, N.2    Ashe, A.3    Zamudio, N.4    Youngson, N.5
  • 35
    • 0037167855 scopus 로고    scopus 로고
    • Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans
    • Herndon LA, Schmeissner PJ, Dudaronek JM, Brown PA, Listner KM, et al. (2002) Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans. Nature 419: 808-814.
    • (2002) Nature , vol.419 , pp. 808-814
    • Herndon, L.A.1    Schmeissner, P.J.2    Dudaronek, J.M.3    Brown, P.A.4    Listner, K.M.5
  • 36
    • 66149094692 scopus 로고    scopus 로고
    • Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila
    • Demontis F, Perrimon N, (2009) Integration of Insulin receptor/Foxo signaling and dMyc activity during muscle growth regulates body size in Drosophila. Development 136: 983-993.
    • (2009) Development , vol.136 , pp. 983-993
    • Demontis, F.1    Perrimon, N.2
  • 37
    • 79954626173 scopus 로고    scopus 로고
    • Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
    • Liu GH, Barkho BZ, Ruiz S, Diep D, Qu J, et al. (2011) Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature 472: 221-225.
    • (2011) Nature , vol.472 , pp. 221-225
    • Liu, G.H.1    Barkho, B.Z.2    Ruiz, S.3    Diep, D.4    Qu, J.5
  • 38
    • 77956520661 scopus 로고    scopus 로고
    • Elevated histone expression promotes life span extension
    • Feser J, Truong D, Das C, Carson JJ, Kieft J, et al. (2010) Elevated histone expression promotes life span extension. Molecular cell 39: 724-735.
    • (2010) Molecular Cell , vol.39 , pp. 724-735
    • Feser, J.1    Truong, D.2    Das, C.3    Carson, J.J.4    Kieft, J.5
  • 39
    • 78049317185 scopus 로고    scopus 로고
    • Aging changes the chromatin configuration and histone methylation of mouse oocytes at germinal vesicle stage
    • Manosalva I, Gonzalez A, (2010) Aging changes the chromatin configuration and histone methylation of mouse oocytes at germinal vesicle stage. Theriogenology 74: 1539-1547.
    • (2010) Theriogenology , vol.74 , pp. 1539-1547
    • Manosalva, I.1    Gonzalez, A.2
  • 40
    • 4444283219 scopus 로고    scopus 로고
    • cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four
    • Sun FL, Haynes K, Simpson CL, Lee SD, Collins L, et al. (2004) cis-Acting determinants of heterochromatin formation on Drosophila melanogaster chromosome four. Mol Cell Biol 24: 8210-8220.
    • (2004) Mol Cell Biol , vol.24 , pp. 8210-8220
    • Sun, F.L.1    Haynes, K.2    Simpson, C.L.3    Lee, S.D.4    Collins, L.5
  • 41
    • 0028286165 scopus 로고
    • Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila
    • Dorer DR, Henikoff S, (1994) Expansions of transgene repeats cause heterochromatin formation and gene silencing in Drosophila. Cell 77: 993-1002.
    • (1994) Cell , vol.77 , pp. 993-1002
    • Dorer, D.R.1    Henikoff, S.2
  • 42
    • 53549088060 scopus 로고    scopus 로고
    • Epigenetic regulation of retrotransposons within the nucleolus of Drosophila
    • Eickbush DG, Ye J, Zhang X, Burke WD, Eickbush TH, (2008) Epigenetic regulation of retrotransposons within the nucleolus of Drosophila. Mol Cell Biol 28: 6452-6461.
    • (2008) Mol Cell Biol , vol.28 , pp. 6452-6461
    • Eickbush, D.G.1    Ye, J.2    Zhang, X.3    Burke, W.D.4    Eickbush, T.H.5
  • 43
    • 17044408768 scopus 로고    scopus 로고
    • JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
    • Wang MC, Bohmann D, Jasper H, (2005) JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121: 115-125.
    • (2005) Cell , vol.121 , pp. 115-125
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 44
    • 33846423520 scopus 로고    scopus 로고
    • Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
    • Hansen M, Taubert S, Crawford D, Libina N, Lee SJ, et al. (2007) Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans. Aging Cell 6: 95-110.
    • (2007) Aging Cell , vol.6 , pp. 95-110
    • Hansen, M.1    Taubert, S.2    Crawford, D.3    Libina, N.4    Lee, S.J.5
  • 45
    • 33846418352 scopus 로고    scopus 로고
    • Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
    • Pan KZ, Palter JE, Rogers AN, Olsen A, Chen D, et al. (2007) Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans. Aging Cell 6: 111-119.
    • (2007) Aging Cell , vol.6 , pp. 111-119
    • Pan, K.Z.1    Palter, J.E.2    Rogers, A.N.3    Olsen, A.4    Chen, D.5
  • 46
    • 34247569105 scopus 로고    scopus 로고
    • Lifespan regulation by evolutionarily conserved genes essential for viability
    • doi:10.1371/journal.pgen.0030056
    • Curran SP, Ruvkun G, (2007) Lifespan regulation by evolutionarily conserved genes essential for viability. PLoS Genet 3: e56 doi:10.1371/journal.pgen.0030056.
    • (2007) PLoS Genet , vol.3
    • Curran, S.P.1    Ruvkun, G.2
  • 47
    • 34447646492 scopus 로고    scopus 로고
    • Longevity determined by developmental arrest genes in Caenorhabditis elegans
    • Chen D, Pan KZ, Palter JE, Kapahi P, (2007) Longevity determined by developmental arrest genes in Caenorhabditis elegans. Aging Cell 6: 525-533.
    • (2007) Aging Cell , vol.6 , pp. 525-533
    • Chen, D.1    Pan, K.Z.2    Palter, J.E.3    Kapahi, P.4
  • 48
    • 43049180299 scopus 로고    scopus 로고
    • Ageing and the regulation of protein synthesis: a balancing act?
    • Tavernarakis N, (2008) Ageing and the regulation of protein synthesis: a balancing act? Trends Cell Biol 18: 228-235.
    • (2008) Trends Cell Biol , vol.18 , pp. 228-235
    • Tavernarakis, N.1
  • 49
    • 41949089130 scopus 로고    scopus 로고
    • Yeast life span extension by depletion of 60 s ribosomal subunits is mediated by Gcn4
    • Steffen KK, MacKay VL, Kerr EO, Tsuchiya M, Hu D, et al. (2008) Yeast life span extension by depletion of 60 s ribosomal subunits is mediated by Gcn4. Cell 133: 292-302.
    • (2008) Cell , vol.133 , pp. 292-302
    • Steffen, K.K.1    MacKay, V.L.2    Kerr, E.O.3    Tsuchiya, M.4    Hu, D.5
  • 50
    • 43049169926 scopus 로고    scopus 로고
    • Epigenetic control of rDNA loci in response to intracellular energy status
    • Murayama A, Ohmori K, Fujimura A, Minami H, Yasuzawa-Tanaka K, et al. (2008) Epigenetic control of rDNA loci in response to intracellular energy status. Cell 133: 627-639.
    • (2008) Cell , vol.133 , pp. 627-639
    • Murayama, A.1    Ohmori, K.2    Fujimura, A.3    Minami, H.4    Yasuzawa-Tanaka, K.5
  • 51
    • 0036499971 scopus 로고    scopus 로고
    • Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing
    • Schotta G, Ebert A, Krauss V, Fischer A, Hoffmann J, et al. (2002) Central role of Drosophila SU(VAR)3-9 in histone H3-K9 methylation and heterochromatic gene silencing. Embo J 21: 1121-1131.
    • (2002) Embo J , vol.21 , pp. 1121-1131
    • Schotta, G.1    Ebert, A.2    Krauss, V.3    Fischer, A.4    Hoffmann, J.5
  • 52
    • 0037847397 scopus 로고    scopus 로고
    • Effects of tethering HP1 to euchromatic regions of the Drosophila genome
    • Li Y, Danzer JR, Alvarez P, Belmont AS, Wallrath LL, (2003) Effects of tethering HP1 to euchromatic regions of the Drosophila genome. Development 130: 1817-1824.
    • (2003) Development , vol.130 , pp. 1817-1824
    • Li, Y.1    Danzer, J.R.2    Alvarez, P.3    Belmont, A.S.4    Wallrath, L.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.