Estrogen receptor-α is required for the osteogenic response to mechanical loading in a ligand-independent manner involving its activation function 1 but not 2

Journal of Bone and Mineral Research

Volumn 28, Issue 2, 2013, Pages 291-301

  Windahl, Sara H ^a   Saxon, Leanne ^b   Börjesson, Anna E ^a   Lagerquist, Marie K ^a   Frenkel, Baruch ^c   Henning, Petra ^a   Lerner, Ulf H ^a,d   Galea, Gabriel L ^e   Meakin, Lee B ^e   Engdahl, Cecilia ^a   Sjögren, Klara ^a   Antal, Maria C ^f   Krust, Andrée ^f   Chambon, Pierre ^f   Lanyon, Lance E ^e   Price, Joanna S ^e   Ohlsson, Claes ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d UMEÅ UNIVERSITY   (Sweden)

^e UNIVERSITY OF BRISTOL   (United Kingdom)

^f INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

Author keywords

bone; Estrogen; loading; mechanical; mouse; receptor

Indexed keywords

CYCLOOXYGENASE 2; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; INTERLEUKIN 11; LUCIFERASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DEVELOPMENT; CORTICAL BONE; ESTROGEN RESPONSIVE ELEMENT; FEMALE; IN VIVO STUDY; MOUSE; NONHUMAN; OSSIFICATION; OVARIECTOMY; PERIOSTEUM; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TIBIA;

ANIMALS; CYCLOOXYGENASE 2; EARLY GROWTH RESPONSE PROTEIN 2; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; GENE EXPRESSION REGULATION; INTERLEUKIN-11; LIGANDS; LUCIFERASES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OSTEOGENESIS; RESPONSE ELEMENTS; RNA, MESSENGER; STRESS, MECHANICAL; TIBIA; WEIGHT-BEARING;

EID: 84872477285     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1754     Document Type: Article

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