Mechanical stress activates smad pathway through PKCδ to enhance interleukin-11 gene transcription in osteoblasts

PLoS ONE

Volumn 5, Issue 9, 2010, Pages

  Kido, Shinsuke ^a   Kuriwaka Kido, Rika ^a   Umino Miyatani, Yuka ^a   Endo, Itsuro ^a   Inoue, Daisuke ^a   Taniguchi, Hisaaki ^b   Inoue, Yasumichi ^c   Imamura, Takeshi ^c   Matsumoto, Toshio ^a  

^a UNIVERSITY OF TOKUSHIMA   (Japan)

^b UNIVERSITY OF TOKUSHIMA   (Japan)

^c CANCER CHEMOTHERAPY CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN; INTERLEUKIN 11; PROTEIN KINASE C DELTA; SMAD PROTEIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR FOSB; TRANSCRIPTION FACTOR JUND;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSCRIPTION; MECHANICAL STRESS; MOLECULAR INTERACTION; MOUSE; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; BONE MORPHOGENETIC PROTEINS; CELL LINE; CELLS, CULTURED; HUMANS; INTERLEUKIN-11; MICE; OSTEOBLASTS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN KINASE C-DELTA; SIGNAL TRANSDUCTION; SMAD PROTEINS; STRESS, MECHANICAL; TRANSCRIPTION, GENETIC;

MURINAE;

EID: 77958564873     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0013090     Document Type: Article

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