A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction

Journal of Biological Chemistry

Volumn 282, Issue 35, 2007, Pages 25501-25508

  Aguirre, J Ignacio ^a,b   Plotkin, Lilian I ^a   Gortazar, Arancha R ^a,c   Millan, Marta Martin ^a   O'Brien, Charles A ^a   Manolagas, Stavros C ^a   Bellido, Teresita ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b University of Florida College of Veterinary Medicine   (United States)

^c HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTORS; OSTEOBLAST MECHANOTRANSDUCTION; TRANSFECTION;

BINDING SITES; BONE; CELL MEMBRANES; LIGANDS; OSTEOBLASTS; SIGNAL TRANSDUCTION;

ENZYME KINETICS;

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; AG 538; CAVEOLIN 1; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ESTROGEN; ESTROGEN RECEPTOR; FULVESTRANT; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN INHIBITOR; SOMATOMEDIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; HUMAN CELL; LIGAND BINDING; MECHANOTRANSDUCTION; MOUSE; NONHUMAN; OSTEOBLAST; OSTEOCLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN FUNCTION; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BONE AND BONES; CAVEOLIN 1; CELL MEMBRANE; CELL NUCLEUS; CELL SURVIVAL; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; ESTROGENS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIGANDS; MAP KINASE SIGNALING SYSTEM; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, KNOCKOUT; MUTATION; OSTEOBLASTS; OSTEOCYTES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; STRESS, MECHANICAL; TRANSFECTION;

MUS;

EID: 34548500327     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M702231200     Document Type: Article

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