-
1
-
-
0023173665
-
The mechanostat: A proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents
-
Frost, H. M. (1987) The mechanostat: a proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents. Bone Miner. 2, 73-85
-
(1987)
Bone Miner.
, vol.2
, pp. 73-85
-
-
Frost, H.M.1
-
2
-
-
23744506557
-
Additive effects of estrogen and mechanical stress on nitric oxide and prostaglandin E2 production by bone cells from osteoporotic donors
-
Bakker, A. D., Klein-Nulend, J., Tanck, E., Albers, G. H., Lips, P., and Burger, E. H. (2005) Additive effects of estrogen and mechanical stress on nitric oxide and prostaglandin E2 production by bone cells from osteoporotic donors. Osteoporos Int. 16, 983-989
-
(2005)
Osteoporos Int.
, vol.16
, pp. 983-989
-
-
Bakker, A.D.1
Klein-Nulend, J.2
Tanck, E.3
Albers, G.H.4
Lips, P.5
Burger, E.H.6
-
3
-
-
0031779953
-
Role of nitric oxide and prostaglandins in mechanically induced bone formation
-
Chow, J. W., Fox, S. W., Lean, J. M., and Chambers, T. J. (1998) Role of nitric oxide and prostaglandins in mechanically induced bone formation. J. Bone Miner. Res. 13, 1039-1044
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 1039-1044
-
-
Chow, J.W.1
Fox, S.W.2
Lean, J.M.3
Chambers, T.J.4
-
4
-
-
0029564705
-
Mechanical strain-induced NO production by bone cells: A possible role in adaptive bone (re)modeling?
-
Pitsillides, A. A., Rawlinson, S. C., Suswillo, R. F., Bourrin, S., Zaman, G., and Lanyon, L. E. (1995) Mechanical strain-induced NO production by bone cells: a possible role in adaptive bone (re)modeling? FASEB J. 9, 1614-1622
-
(1995)
FASEB J.
, vol.9
, pp. 1614-1622
-
-
Pitsillides, A.A.1
Rawlinson, S.C.2
Suswillo, R.F.3
Bourrin, S.4
Zaman, G.5
Lanyon, L.E.6
-
5
-
-
0032971265
-
Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes
-
Zaman, G., Pitsillides, A. A., Rawlinson, S. C., Suswillo, R. F., Mosley, J. R., Cheng, M. Z., Platts, L. A., Hukkanen, M., Polak, J. M., and Lanyon, L. E. (1999) Mechanical strain stimulates nitric oxide production by rapid activation of endothelial nitric oxide synthase in osteocytes. J. Bone Miner. Res. 14, 1123-1131
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1123-1131
-
-
Zaman, G.1
Pitsillides, A.A.2
Rawlinson, S.C.3
Suswillo, R.F.4
Mosley, J.R.5
Cheng, M.Z.6
Platts, L.A.7
Hukkanen, M.8
Polak, J.M.9
Lanyon, L.E.10
-
6
-
-
0029998565
-
Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo
-
Forwood, M. R. (1996) Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo. J. Bone Miner. Res. 11, 1688-1693
-
(1996)
J. Bone Miner. Res.
, vol.11
, pp. 1688-1693
-
-
Forwood, M.R.1
-
7
-
-
0036551229
-
Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading
-
Li, J., Burr, D. B., and Turner, C. H. (2002) Suppression of prostaglandin synthesis with NS-398 has different effects on endocortical and periosteal bone formation induced by mechanical loading. Calcif. Tissue Int. 70, 320-329
-
(2002)
Calcif. Tissue Int.
, vol.70
, pp. 320-329
-
-
Li, J.1
Burr, D.B.2
Turner, C.H.3
-
8
-
-
0036312822
-
Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways
-
Jessop, H. L., Rawlinson, S. C., Pitsillides, A. A., and Lanyon, L. E. (2002) Mechanical strain and fluid movement both activate extracellular regulated kinase (ERK) in osteoblast-like cells but via different signaling pathways. Bone 31, 186-194
-
(2002)
Bone
, vol.31
, pp. 186-194
-
-
Jessop, H.L.1
Rawlinson, S.C.2
Pitsillides, A.A.3
Lanyon, L.E.4
-
9
-
-
34548500327
-
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction
-
Aguirre, J. I., Plotkin, L. I., Gortazar, A. R., Millan, M. M., O'Brien, C. A., Manolagas, S. C., and Bellido, T. (2007) A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction. J. Biol. Chem. 282, 25501-25508
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 25501-25508
-
-
Aguirre, J.I.1
Plotkin, L.I.2
Gortazar, A.R.3
Millan, M.M.4
O'Brien, C.A.5
Manolagas, S.C.6
Bellido, T.7
-
10
-
-
0031859351
-
The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain
-
Damien, E., Price, J. S., and Lanyon, L. E. (1998) The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain. J. Bone Miner. Res. 13, 1275-1282
-
(1998)
J. Bone Miner. Res.
, vol.13
, pp. 1275-1282
-
-
Damien, E.1
Price, J.S.2
Lanyon, L.E.3
-
11
-
-
0033911094
-
Mechanical strain activates estrogen response elements in bone cells
-
Zaman, G., Cheng, M. Z., Jessop, H. L., White, R., and Lanyon, L. E. (2000) Mechanical strain activates estrogen response elements in bone cells. Bone 27, 233-239
-
(2000)
Bone
, vol.27
, pp. 233-239
-
-
Zaman, G.1
Cheng, M.Z.2
Jessop, H.L.3
White, R.4
Lanyon, L.E.5
-
12
-
-
0032834127
-
Mechanical strain stimulates ROS cell proliferation through IGF-II and estrogen through IGF-I
-
Cheng, M., Zaman, G., Rawlinson, S. C., Mohan, S., Baylink, D. J., and Lanyon, L. E. (1999) Mechanical strain stimulates ROS cell proliferation through IGF-II and estrogen through IGF-I. J. Bone Miner. Res. 14, 1742-1750
-
(1999)
J. Bone Miner. Res.
, vol.14
, pp. 1742-1750
-
-
Cheng, M.1
Zaman, G.2
Rawlinson, S.C.3
Mohan, S.4
Baylink, D.J.5
Lanyon, L.E.6
-
13
-
-
0033791733
-
Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females
-
Damien, E., Price, J. S., and Lanyon, L. E. (2000) Mechanical strain stimulates osteoblast proliferation through the estrogen receptor in males as well as females. J. Bone Miner. Res. 15, 2169-2177
-
(2000)
J. Bone Miner. Res.
, vol.15
, pp. 2169-2177
-
-
Damien, E.1
Price, J.S.2
Lanyon, L.E.3
-
14
-
-
16544367196
-
Effect of strain on bone nodule formation by rat osteogenic cells in vitro
-
Visconti, L. A., Yen, E. H., and Johnson, R. B. (2004) Effect of strain on bone nodule formation by rat osteogenic cells in vitro. Arch. Oral Biol. 49, 485-492
-
(2004)
Arch. Oral Biol.
, vol.49
, pp. 485-492
-
-
Visconti, L.A.1
Yen, E.H.2
Johnson, R.B.3
-
15
-
-
0030968233
-
Early responses to dynamic strain change and prostaglandins in bone-derived cells in culture
-
Zaman, G., Suswillo, R. F., Cheng, M. Z., Tavares, I. A., and Lanyon, L. E. (1997) Early responses to dynamic strain change and prostaglandins in bone-derived cells in culture. J. Bone Miner. Res. 12, 769-777
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 769-777
-
-
Zaman, G.1
Suswillo, R.F.2
Cheng, M.Z.3
Tavares, I.A.4
Lanyon, L.E.5
-
16
-
-
34547111836
-
Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α
-
Armstrong, V. J., Muzylak, M., Sunters, A., Zaman, G., Saxon, L. K., Price, J. S., and Lanyon, L. E. (2007) Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α. J. Biol. Chem. 282, 20715-20727
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 20715-20727
-
-
Armstrong, V.J.1
Muzylak, M.2
Sunters, A.3
Zaman, G.4
Saxon, L.K.5
Price, J.S.6
Lanyon, L.E.7
-
17
-
-
33646902229
-
Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear
-
Lau, K. H., Kapur, S., Kesavan, C., and Baylink, D. J. (2006) Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear. J. Biol. Chem. 281, 9576-9588
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 9576-9588
-
-
Lau, K.H.1
Kapur, S.2
Kesavan, C.3
Baylink, D.J.4
-
18
-
-
41949089764
-
Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin
-
Robling, A. G., Niziolek, P. J., Baldridge, L. A., Condon, K. W., Allen, M. R., Alam, I., Mantila, S. M., Gluhak-Heinrich, J., Bellido, T. M., Harris, S. E., and Turner, C. H. (2008) Mechanical stimulation of bone in vivo reduces osteocyte expression of Sost/sclerostin. J. Biol. Chem. 283, 5866-5875
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 5866-5875
-
-
Robling, A.G.1
Niziolek, P.J.2
Baldridge, L.A.3
Condon, K.W.4
Allen, M.R.5
Alam, I.6
Mantila, S.M.7
Gluhak-Heinrich, J.8
Bellido, T.M.9
Harris, S.E.10
Turner, C.H.11
-
19
-
-
77649181032
-
Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse
-
Zaman, G., Saxon, L. K., Sunters, A., Hilton, H., Underhill, P., Williams, D., Price, J. S., and Lanyon, L. E. (2010) Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor alpha and disuse. Bone 46, 628-642
-
(2010)
Bone
, vol.46
, pp. 628-642
-
-
Zaman, G.1
Saxon, L.K.2
Sunters, A.3
Hilton, H.4
Underhill, P.5
Williams, D.6
Price, J.S.7
Lanyon, L.E.8
-
20
-
-
0030060372
-
Defective bone formation in Krox-20 mutant mice
-
Levi, G., Topilko, P., Schneider-Maunoury, S., Lasagna, M., Mantero, S., Cancedda, R., and Charnay, P. (1996) Defective bone formation in Krox-20 mutant mice. Development 122, 113-120
-
(1996)
Development
, vol.122
, pp. 113-120
-
-
Levi, G.1
Topilko, P.2
Schneider-Maunoury, S.3
Lasagna, M.4
Mantero, S.5
Cancedda, R.6
Charnay, P.7
-
21
-
-
70349117354
-
Promiscuous and depolarization-induced immediate-early response genes are induced by mechanical strain of osteoblasts
-
Ott, C. E., Bauer, S., Manke, T., Ahrens, S., Rödelsperger, C., Grünhagen, J., Kornak, U., Duda, G., Mundlos, S., and Robinson, P. N. (2009) Promiscuous and depolarization-induced immediate-early response genes are induced by mechanical strain of osteoblasts. J. Bone Miner. Res. 24, 1247-1262
-
(2009)
J. Bone Miner. Res.
, vol.24
, pp. 1247-1262
-
-
Ott, C.E.1
Bauer, S.2
Manke, T.3
Ahrens, S.4
Rödelsperger, C.5
Grünhagen, J.6
Kornak, U.7
Duda, G.8
Mundlos, S.9
Robinson, P.N.10
-
22
-
-
52449085471
-
Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice
-
Sugiyama, T., Saxon, L. K., Zaman, G., Moustafa, A., Sunters, A., Price, J. S., and Lanyon, L. (2008) Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice. Bone 43, 238-248
-
(2008)
Bone
, vol.43
, pp. 238-248
-
-
Sugiyama, T.1
Saxon, L.K.2
Zaman, G.3
Moustafa, A.4
Sunters, A.5
Price, J.S.6
Lanyon, L.7
-
23
-
-
74249114163
-
Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones
-
Sugiyama, T., Price, J. S., and Lanyon, L. E. (2010) Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone 46, 314-321
-
(2010)
Bone
, vol.46
, pp. 314-321
-
-
Sugiyama, T.1
Price, J.S.2
Lanyon, L.E.3
-
24
-
-
0032530109
-
Blocking ligand occupancy of the alpha Vbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells
-
Zheng, B., and Clemmons, D. R. (1998) Blocking ligand occupancy of the alpha Vbeta3 integrin inhibits insulin-like growth factor I signaling in vascular smooth muscle cells. Proc. Natl. Acad. Sci. U.S.A. 95, 11217-11222
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 11217-11222
-
-
Zheng, B.1
Clemmons, D.R.2
-
25
-
-
33746451702
-
Osteocytes use estrogen receptor alpha to respond to strain but their ERalpha content is regulated by estrogen
-
Zaman, G., Jessop, H. L., Muzylak, M., De Souza, R. L., Pitsillides, A. A., Price, J. S., and Lanyon, L. L. (2006) Osteocytes use estrogen receptor alpha to respond to strain but their ERalpha content is regulated by estrogen. J. Bone Miner. Res. 21, 1297-1306
-
(2006)
J. Bone Miner. Res.
, vol.21
, pp. 1297-1306
-
-
Zaman, G.1
Jessop, H.L.2
Muzylak, M.3
De Souza, R.L.4
Pitsillides, A.A.5
Price, J.S.6
Lanyon, L.L.7
-
26
-
-
60149084519
-
PASTAA: Identifying transcription factors associated with sets of co-regulated genes
-
Roider, H. G., Manke, T., O'Keeffe, S., Vingron, M., and Haas, S. A. (2009) PASTAA: identifying transcription factors associated with sets of co-regulated genes. Bioinformatics 25, 435-442
-
(2009)
Bioinformatics
, vol.25
, pp. 435-442
-
-
Roider, H.G.1
Manke, T.2
O'Keeffe, S.3
Vingron, M.4
Haas, S.A.5
-
27
-
-
33846700587
-
Predicting transcription factor affinities to DNA from a biophysical model
-
Roider, H. G., Kanhere, A., Manke, T., and Vingron, M. (2007) Predicting transcription factor affinities to DNA from a biophysical model. Bioinformatics 23, 134-141
-
(2007)
Bioinformatics
, vol.23
, pp. 134-141
-
-
Roider, H.G.1
Kanhere, A.2
Manke, T.3
Vingron, M.4
-
28
-
-
2942711895
-
Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways
-
Sakata, T., Wang, Y., Halloran, B. P., Elalieh, H. Z., Cao, J., and Bikle, D. D. (2004) Skeletal unloading induces resistance to insulin-like growth factor-I (IGF-I) by inhibiting activation of the IGF-I signaling pathways. J. Bone Miner. Res. 19, 436-446
-
(2004)
J. Bone Miner. Res.
, vol.19
, pp. 436-446
-
-
Sakata, T.1
Wang, Y.2
Halloran, B.P.3
Elalieh, H.Z.4
Cao, J.5
Bikle, D.D.6
-
29
-
-
21244443034
-
Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway
-
Kapur, S., Mohan, S., Baylink, D. J., and Lau, K. H. (2005) Fluid shear stress synergizes with insulin-like growth factor-I (IGF-I) on osteoblast proliferation through integrin-dependent activation of IGF-I mitogenic signaling pathway. J. Biol. Chem. 280, 20163-20170
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20163-20170
-
-
Kapur, S.1
Mohan, S.2
Baylink, D.J.3
Lau, K.H.4
-
30
-
-
0034698147
-
Ligand binding to integrins
-
Plow, E. F., Haas, T. A., Zhang, L., Loftus, J., and Smith, J. W. (2000) Ligand binding to integrins. J. Biol. Chem. 275, 21785-21788
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 21785-21788
-
-
Plow, E.F.1
Haas, T.A.2
Zhang, L.3
Loftus, J.4
Smith, J.W.5
-
31
-
-
77957155478
-
Antagonistic interplay between mechanical forces and glucocorticoids in bone: A tale of kinases
-
Bellido, T. (2010) Antagonistic interplay between mechanical forces and glucocorticoids in bone: a tale of kinases. J. Cell. Biochem. 111, 1-6
-
(2010)
J. Cell. Biochem.
, vol.111
, pp. 1-6
-
-
Bellido, T.1
-
32
-
-
0033430117
-
Cell adhesion: Old and new questions
-
Hynes, R. O. (1999) Cell adhesion: old and new questions. Trends Cell Biol. 9, M33-M37
-
(1999)
Trends Cell Biol.
, vol.9
-
-
Hynes, R.O.1
-
33
-
-
0030570270
-
Expression of heme oxygenase and inducible nitric-oxide synthase mRNA in human brain tumors
-
Hara, E., Takahashi, K., Tominaga, T., Kumabe, T., Kayama, T., Suzuki, H., Fujita, H., Yoshimoto, T., Shirato, K., and Shibahara, S. (1996) Expression of heme oxygenase and inducible nitric-oxide synthase mRNA in human brain tumors. Biochem. Biophys. Res. Commun. 224, 153-158
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 153-158
-
-
Hara, E.1
Takahashi, K.2
Tominaga, T.3
Kumabe, T.4
Kayama, T.5
Suzuki, H.6
Fujita, H.7
Yoshimoto, T.8
Shirato, K.9
Shibahara, S.10
-
34
-
-
0344893596
-
Estrogen enhances the stimulation of bone collagen synthesis by loading and exogenous prostacyclin, but not prostaglandin E2, in organ cultures of rat ulnae
-
Cheng, M. Z., Zaman, G., and Lanyon, L. E. (1994) Estrogen enhances the stimulation of bone collagen synthesis by loading and exogenous prostacyclin, but not prostaglandin E2, in organ cultures of rat ulnae. J. Bone Miner. Res. 9, 805-816
-
(1994)
J. Bone Miner. Res.
, vol.9
, pp. 805-816
-
-
Cheng, M.Z.1
Zaman, G.2
Lanyon, L.E.3
-
35
-
-
77950519110
-
Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells
-
Liedert, A., Wagner, L., Seefried, L., Ebert, R., Jakob, F., and Ignatius, A. (2010) Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells. Biochem. Biophys. Res. Commun. 394, 755-759
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.394
, pp. 755-759
-
-
Liedert, A.1
Wagner, L.2
Seefried, L.3
Ebert, R.4
Jakob, F.5
Ignatius, A.6
-
36
-
-
78649814990
-
Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice
-
Sugiyama, T., Galea, G. L., Lanyon, L. E., and Price, J. S. (2010) Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice. Endocrinology 151, 5582-5590
-
(2010)
Endocrinology
, vol.151
, pp. 5582-5590
-
-
Sugiyama, T.1
Galea, G.L.2
Lanyon, L.E.3
Price, J.S.4
-
37
-
-
0346102686
-
Efficacy data on teriparatide (parathyroid hormone) in patients with postmenopausal osteoporosis
-
Debiais, F. (2003) Efficacy data on teriparatide (parathyroid hormone) in patients with postmenopausal osteoporosis. Joint Bone Spine 70, 465-470
-
(2003)
Joint Bone Spine
, vol.70
, pp. 465-470
-
-
Debiais, F.1
-
38
-
-
0037045407
-
Parathyroid hormone-dependent signaling pathways regulating genes in bone cells
-
Swarthout, J. T., D'Alonzo, R. C., Selvamurugan, N., and Partridge, N. C. (2002) Parathyroid hormone-dependent signaling pathways regulating genes in bone cells. Gene 282, 1-17
-
(2002)
Gene
, vol.282
, pp. 1-17
-
-
Swarthout, J.T.1
D'Alonzo, R.C.2
Selvamurugan, N.3
Partridge, N.C.4
-
39
-
-
0033166193
-
The role of prostaglandins and nitric oxide in the response of bone to mechanical forces
-
Chambers, T. J., Fox, S., Jagger, C. J., Lean, J. M., and Chow, J. W. (1999) The role of prostaglandins and nitric oxide in the response of bone to mechanical forces. Osteoarthritis Cartilage 7, 422-423
-
(1999)
Osteoarthritis Cartilage
, vol.7
, pp. 422-423
-
-
Chambers, T.J.1
Fox, S.2
Jagger, C.J.3
Lean, J.M.4
Chow, J.W.5
-
40
-
-
0028929151
-
Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation
-
Lean, J. M., Jagger, C. J., Chambers, T. J., and Chow, J. W. (1995) Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation. Am. J. Physiol. 268, E318-E327
-
(1995)
Am. J. Physiol.
, vol.268
-
-
Lean, J.M.1
Jagger, C.J.2
Chambers, T.J.3
Chow, J.W.4
-
41
-
-
0027521175
-
Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture
-
Rawlinson, S. C., Mohan, S., Baylink, D. J., and Lanyon, L. E. (1993) Exogenous prostacyclin, but not prostaglandin E2, produces similar responses in both G6PD activity and RNA production as mechanical loading, and increases IGF-II release, in adult cancellous bone in culture. Calcif. Tissue Int. 53, 324-329
-
(1993)
Calcif. Tissue Int.
, vol.53
, pp. 324-329
-
-
Rawlinson, S.C.1
Mohan, S.2
Baylink, D.J.3
Lanyon, L.E.4
-
42
-
-
77950567146
-
Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling
-
Sunters, A., Armstrong, V. J., Zaman, G., Kypta, R. M., Kawano, Y., Lanyon, L. E., and Price, J. S. (2010) Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling. J. Biol. Chem. 285, 8743-8758
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 8743-8758
-
-
Sunters, A.1
Armstrong, V.J.2
Zaman, G.3
Kypta, R.M.4
Kawano, Y.5
Lanyon, L.E.6
Price, J.S.7
-
43
-
-
0029127979
-
Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats
-
Watson, P., Lazowski, D., Han, V., Fraher, L., Steer, B., and Hodsman, A. (1995) Parathyroid hormone restores bone mass and enhances osteoblast insulin-like growth factor I gene expression in ovariectomized rats. Bone 16, 357-365
-
(1995)
Bone
, vol.16
, pp. 357-365
-
-
Watson, P.1
Lazowski, D.2
Han, V.3
Fraher, L.4
Steer, B.5
Hodsman, A.6
-
44
-
-
77954851049
-
Wnt signaling regulates mitochondrial physiology and insulin sensitivity
-
Yoon, J. C., Ng, A., Kim, B. H., Bianco, A., Xavier, R. J., and Elledge, S. J. (2010) Wnt signaling regulates mitochondrial physiology and insulin sensitivity. Genes Dev. 24, 1507-1518
-
(2010)
Genes Dev.
, vol.24
, pp. 1507-1518
-
-
Yoon, J.C.1
Ng, A.2
Kim, B.H.3
Bianco, A.4
Xavier, R.J.5
Elledge, S.J.6
-
45
-
-
33751032130
-
Wnt signaling: A key regulator of bone mass
-
Baron, R., Rawadi, G., and Roman-Roman, S. (2006) Wnt signaling: a key regulator of bone mass. Curr. Top. Dev. Biol. 76, 103-127
-
(2006)
Curr. Top. Dev. Biol.
, vol.76
, pp. 103-127
-
-
Baron, R.1
Rawadi, G.2
Roman-Roman, S.3
-
46
-
-
13244298422
-
Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins
-
Winkler, D. G., Sutherland, M. S., Ojala, E., Turcott, E., Geoghegan, J. C., Shpektor, D., Skonier, J. E., Yu, C., and Latham, J. A. (2005) Sclerostin inhibition of Wnt-3a-induced C3H10T1/2 cell differentiation is indirect and mediated by bone morphogenetic proteins. J. Biol. Chem. 280, 2498-2502
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 2498-2502
-
-
Winkler, D.G.1
Sutherland, M.S.2
Ojala, E.3
Turcott, E.4
Geoghegan, J.C.5
Shpektor, D.6
Skonier, J.E.7
Yu, C.8
Latham, J.A.9
-
47
-
-
63449096161
-
The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading
-
Moustafa, A., Sugiyama, T., Saxon, L. K., Zaman, G., Sunters, A., Armstrong, V. J., Javaheri, B., Lanyon, L. E., and Price, J. S. (2009) The mouse fibula as a suitable bone for the study of functional adaptation to mechanical loading. Bone 44, 930-935
-
(2009)
Bone
, vol.44
, pp. 930-935
-
-
Moustafa, A.1
Sugiyama, T.2
Saxon, L.K.3
Zaman, G.4
Sunters, A.5
Armstrong, V.J.6
Javaheri, B.7
Lanyon, L.E.8
Price, J.S.9
-
48
-
-
79960922344
-
Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4
-
Galea, G. L., Sunters, A., Meakin, L. B., Zaman, G., Sugiyama, T., Lanyon, L. E., and Price, J. S. (2011) Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4. FEBS Lett. 585, 2450-2454
-
(2011)
FEBS Lett.
, vol.585
, pp. 2450-2454
-
-
Galea, G.L.1
Sunters, A.2
Meakin, L.B.3
Zaman, G.4
Sugiyama, T.5
Lanyon, L.E.6
Price, J.S.7
-
49
-
-
0031943222
-
Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies
-
Warner, L. E., Mancias, P., Butler, I. J., McDonald, C. M., Keppen, L., Koob, K. G., and Lupski, J. R. (1998) Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies. Nat. Genet. 18, 382-384
-
(1998)
Nat. Genet.
, vol.18
, pp. 382-384
-
-
Warner, L.E.1
Mancias, P.2
Butler, I.J.3
McDonald, C.M.4
Keppen, L.5
Koob, K.G.6
Lupski, J.R.7
-
50
-
-
0033208622
-
A novel mutation (D305V) in the early growth response 2 gene is associated with severe Charcot-Marie-Tooth type 1 disease
-
Bellone, E., Di Maria, E., Soriani, S., Varese, A., Doria, L. L., Ajmar, F., and Mandich, P. (1999) A novel mutation (D305V) in the early growth response 2 gene is associated with severe Charcot-Marie-Tooth type 1 disease. Hum. Mutat. 14, 353-354
-
(1999)
Hum. Mutat.
, vol.14
, pp. 353-354
-
-
Bellone, E.1
Di Maria, E.2
Soriani, S.3
Varese, A.4
Doria, L.L.5
Ajmar, F.6
Mandich, P.7
-
51
-
-
9544222720
-
The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation
-
Nonchev, S., Maconochie, M., Vesque, C., Aparicio, S., Ariza-Mc- Naughton, L., Manzanares, M., Maruthainar, K., Kuroiwa, A., Brenner, S., Charnay, P., and Krumlauf, R. (1996) The conserved role of Krox-20 in directing Hox gene expression during vertebrate hindbrain segmentation. Proc. Natl. Acad. Sci. U.S.A. 93, 9339-9345
-
(1996)
Proc. Natl. Acad. Sci. U.S.A.
, vol.93
, pp. 9339-9345
-
-
Nonchev, S.1
Maconochie, M.2
Vesque, C.3
Aparicio, S.4
Ariza-Mc- Naughton, L.5
Manzanares, M.6
Maruthainar, K.7
Kuroiwa, A.8
Brenner, S.9
Charnay, P.10
Krumlauf, R.11
-
52
-
-
0027135790
-
Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain
-
Schneider-Maunoury, S., Topilko, P., Seitandou, T., Levi, G., Cohen-Tannoudji, M., Pournin, S., Babinet, C., and Charnay, P. (1993) Disruption of Krox-20 results in alteration of rhombomeres 3 and 5 in the developing hindbrain. Cell 75, 1199-1214
-
(1993)
Cell
, vol.75
, pp. 1199-1214
-
-
Schneider-Maunoury, S.1
Topilko, P.2
Seitandou, T.3
Levi, G.4
Cohen-Tannoudji, M.5
Pournin, S.6
Babinet, C.7
Charnay, P.8
-
53
-
-
0037046806
-
Establishment of hindbrain segmental identity requires signaling by FGF3 and FGF8
-
Walshe, J., Maroon, H., McGonnell, I. M., Dickson, C., and Mason, I. (2002) Establishment of hindbrain segmental identity requires signaling by FGF3 and FGF8. Curr. Biol. 12, 1117-1123
-
(2002)
Curr. Biol.
, vol.12
, pp. 1117-1123
-
-
Walshe, J.1
Maroon, H.2
McGonnell, I.M.3
Dickson, C.4
Mason, I.5
-
54
-
-
0036381068
-
Krox-20/egr-2 is upregulated following non-specific and homophilic adhesion in rat macrophages
-
Hirano, S., Anuradha, C. D., and Kanno, S. (2002) krox-20/egr-2 is upregulated following non-specific and homophilic adhesion in rat macrophages. Immunology 107, 86-92
-
(2002)
Immunology
, vol.107
, pp. 86-92
-
-
Hirano, S.1
Anuradha, C.D.2
Kanno, S.3
-
55
-
-
0036197017
-
Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse
-
Grose, R., Harris, B. S., Cooper, L., Topilko, P., and Martin, P. (2002) Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse. Dev. Dyn. 223, 371-378
-
(2002)
Dev. Dyn.
, vol.223
, pp. 371-378
-
-
Grose, R.1
Harris, B.S.2
Cooper, L.3
Topilko, P.4
Martin, P.5
-
56
-
-
0028790658
-
Hypoglycemia-elicited immediate early gene expression in neurons and glia of the hippocampus: Novel patterns of FOS, JUN, and KROX expression following excitotoxic injury
-
Gass, P., Katsura, K., Zuschratter, W., Siesjö, B., and Kiessling, M. (1995) Hypoglycemia-elicited immediate early gene expression in neurons and glia of the hippocampus: novel patterns of FOS, JUN, and KROX expression following excitotoxic injury. J. Cereb. Blood Flow Metab. 15, 989-1001
-
(1995)
J. Cereb. Blood Flow Metab.
, vol.15
, pp. 989-1001
-
-
Gass, P.1
Katsura, K.2
Zuschratter, W.3
Siesjö, B.4
Kiessling, M.5
-
57
-
-
0033831565
-
Transcription of krox- 20/egr-2 is upregulated after exposure to fibrous particles and adhesion in rat alveolar macrophages
-
Hirano, S., Anuradha, C. D., and Kanno, S. (2000) Transcription of krox- 20/egr-2 is upregulated after exposure to fibrous particles and adhesion in rat alveolar macrophages. Am. J. Respir. Cell Mol. Biol. 23, 313-319
-
(2000)
Am. J. Respir. Cell Mol. Biol.
, vol.23
, pp. 313-319
-
-
Hirano, S.1
Anuradha, C.D.2
Kanno, S.3
-
58
-
-
0029762387
-
Role of Krox-20 in endochondral bone formation
-
Levi, G., Topilko, P., Schneider-Maunoury, S., Lasagna, M., Mantero, S., Pesce, B., Ghersi, G., Cancedda, R., and Charnay, P. (1996) Role of Krox-20 in endochondral bone formation. Ann. N.Y. Acad. Sci. 785, 288-291
-
(1996)
Ann. N.Y. Acad. Sci.
, vol.785
, pp. 288-291
-
-
Levi, G.1
Topilko, P.2
Schneider-Maunoury, S.3
Lasagna, M.4
Mantero, S.5
Pesce, B.6
Ghersi, G.7
Cancedda, R.8
Charnay, P.9
-
59
-
-
4444276363
-
Gene expression profiling of glucocorticoid-inhibited osteoblasts
-
Leclerc, N., Luppen, C. A., Ho, V. V., Nagpal, S., Hacia, J. G., Smith, E., and Frenkel, B. (2004) Gene expression profiling of glucocorticoid-inhibited osteoblasts. J. Mol. Endocrinol. 33, 175-193
-
(2004)
J. Mol. Endocrinol.
, vol.33
, pp. 175-193
-
-
Leclerc, N.1
Luppen, C.A.2
Ho, V.V.3
Nagpal, S.4
Hacia, J.G.5
Smith, E.6
Frenkel, B.7
-
60
-
-
41849099277
-
Opposing effects of glucocorticoids and Wnt signaling on Krox20 and mineral deposition in osteoblast cultures
-
Leclerc, N., Noh, T., Cogan, J., Samarawickrama, D. B., Smith, E., and Frenkel, B. (2008) Opposing effects of glucocorticoids and Wnt signaling on Krox20 and mineral deposition in osteoblast cultures. J. Cell. Biochem. 103, 1938-1951
-
(2008)
J. Cell. Biochem.
, vol.103
, pp. 1938-1951
-
-
Leclerc, N.1
Noh, T.2
Cogan, J.3
Samarawickrama, D.B.4
Smith, E.5
Frenkel, B.6
-
61
-
-
14944356482
-
Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer
-
Leclerc, N., Noh, T., Khokhar, A., Smith, E., and Frenkel, B. (2005) Glucocorticoids inhibit osteocalcin transcription in osteoblasts by suppressing Egr2/Krox20-binding enhancer. Arthritis Rheum. 52, 929-939
-
(2005)
Arthritis Rheum.
, vol.52
, pp. 929-939
-
-
Leclerc, N.1
Noh, T.2
Khokhar, A.3
Smith, E.4
Frenkel, B.5
-
62
-
-
78650926548
-
Gene expression patterns in bone following mechanical loading
-
Mantila Roosa, S. M., Liu, Y., and Turner, C. H. (2011) Gene expression patterns in bone following mechanical loading. J. Bone Miner. Res. 26, 100-112
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 100-112
-
-
Mantila Roosa, S.M.1
Liu, Y.2
Turner, C.H.3
-
63
-
-
34248577022
-
Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
-
Jilka, R. L. (2007) Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 40, 1434-1446
-
(2007)
Bone
, vol.40
, pp. 1434-1446
-
-
Jilka, R.L.1
-
64
-
-
23944499058
-
Mechanical stimulation prevents osteocyte apoptosis: Requirement of integrins, Src kinases, and ERKs
-
Plotkin, L. I., Mathov, I., Aguirre, J. I., Parfitt, A. M., Manolagas, S. C., and Bellido, T. (2005) Mechanical stimulation prevents osteocyte apoptosis: requirement of integrins, Src kinases, and ERKs. Am. J. Physiol. Cell Physiol 289, C633-C643
-
(2005)
Am. J. Physiol. Cell Physiol
, vol.289
-
-
Plotkin, L.I.1
Mathov, I.2
Aguirre, J.I.3
Parfitt, A.M.4
Manolagas, S.C.5
Bellido, T.6
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