Sost down-regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

FEBS Letters

Volumn 585, Issue 15, 2011, Pages 2450-2454

  Galea, Gabriel L ^a,b   Sunters, Andrew ^b   Meakin, Lee B ^a   Zaman, Gul ^b   Sugiyama, Toshihiro ^a   Lanyon, Lance E ^a,b   Price, Joanna S ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b ROYAL VETERINARY COLLEGE   (United Kingdom)

Author keywords

Mechanical strain; Osteoporosis; PGE2 signaling; Sclerostin

Indexed keywords

CYCLOOXYGENASE 2; MITOGEN ACTIVATED PROTEIN KINASE; OSTEOCALCIN; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; PROTEIN KINASE C; SCLEROSTIN;

ARTICLE; CELL LINE; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MECHANICAL STRAIN; MECHANICS; OSTEOBLAST; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; UPREGULATION;

BIOMECHANICS; BONE MORPHOGENETIC PROTEINS; CELLS, CULTURED; DINOPROSTONE; DOWN-REGULATION; GENETIC MARKERS; HUMANS; OSTEOBLASTS; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 79960922344     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.06.019     Document Type: Article

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