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Volumn 43, Issue 2, 2008, Pages 238-248

Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice

Author keywords

Adaptation; Mechanical loading; Micro computed tomography; Mouse; Parathyroid hormone

Indexed keywords

PARATHYROID HORMONE[1-34]; PARATHYROID HORMONE; PTH PROTEIN, HUMAN;

EID: 52449085471     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.04.012     Document Type: Article
Times cited : (150)

References (45)
  • 1
    • 33750209491 scopus 로고    scopus 로고
    • An estimate of the worldwide prevalence and disability associated with osteoporotic fractures
    • Johnell O, Kanis JA. An estimate of the worldwide prevalence and disability associated with osteoporotic fractures. Osteoporos Int 2006;17:1726-33.
    • (2006) Osteoporos Int , vol.17 , pp. 1726-1733
    • Johnell, O.1    Kanis, J.A.2
  • 2
    • 33744992495 scopus 로고    scopus 로고
    • Osteoporosis
    • Sambrook P, Cooper C. Osteoporosis. Lancet 2006;367:2010-8.
    • (2006) Lancet , vol.367 , pp. 2010-2018
    • Sambrook, P.1    Cooper, C.2
  • 3
    • 33845970601 scopus 로고    scopus 로고
    • Osteoporosis and its management
    • Poole KE, Compston JE. Osteoporosis and its management. BMJ 2006;333:1251-6.
    • (2006) BMJ , vol.333 , pp. 1251-1256
    • Poole, K.E.1    Compston, J.E.2
  • 4
    • 34548306408 scopus 로고    scopus 로고
    • Mechanisms of anabolic therapies for osteoporosis
    • Canalis E, Giustina A, Bilezikian JP. Mechanisms of anabolic therapies for osteoporosis. N Engl J Med 2007;357:905-16.
    • (2007) N Engl J Med , vol.357 , pp. 905-916
    • Canalis, E.1    Giustina, A.2    Bilezikian, J.P.3
  • 5
    • 0018839378 scopus 로고
    • Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: A multicentre trial
    • Reeve J, Meunier PJ, Parsons JA, Bernat M, Bijvoet OL, Courpron P, et al. Anabolic effect of human parathyroid hormone fragment on trabecular bone in involutional osteoporosis: a multicentre trial. Br Med J 1980;280:1340-4.
    • (1980) Br Med J , vol.280 , pp. 1340-1344
    • Reeve, J.1    Meunier, P.J.2    Parsons, J.A.3    Bernat, M.4    Bijvoet, O.L.5    Courpron, P.6
  • 6
    • 0035837553 scopus 로고    scopus 로고
    • Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis
    • Neer RM, Arnaud CD, Zanchetta JR, Prince R, Gaich GA, Reginster JY, et al. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med 2001;344:1434-41.
    • (2001) N Engl J Med , vol.344 , pp. 1434-1441
    • Neer, R.M.1    Arnaud, C.D.2    Zanchetta, J.R.3    Prince, R.4    Gaich, G.A.5    Reginster, J.Y.6
  • 7
    • 0037160714 scopus 로고    scopus 로고
    • Recombinant human parathyroid hormone
    • Reeve J. Recombinant human parathyroid hormone. BMJ 2002;324:435-6.
    • (2002) BMJ , vol.324 , pp. 435-436
    • Reeve, J.1
  • 10
    • 21344454577 scopus 로고    scopus 로고
    • Parathyroid hormone and teriparatide for the treatment of osteoporosis: A review of the evidence and suggested guidelines for its use
    • Hodsman AB, Bauer DC, Dempster DW, Dian L, Hanley DA, Harris ST, et al. Parathyroid hormone and teriparatide for the treatment of osteoporosis: a review of the evidence and suggested guidelines for its use. Endocr Rev 2005;26:688-703.
    • (2005) Endocr Rev , vol.26 , pp. 688-703
    • Hodsman, A.B.1    Bauer, D.C.2    Dempster, D.W.3    Dian, L.4    Hanley, D.A.5    Harris, S.T.6
  • 11
    • 26044477835 scopus 로고    scopus 로고
    • Does early PTH treatment compromise bone strength? The balance between remodeling, porosity, bone mineral, and bone size
    • Burr DB. Does early PTH treatment compromise bone strength? The balance between remodeling, porosity, bone mineral, and bone size. Curr Osteoporos Rep 2005;3:19-24.
    • (2005) Curr Osteoporos Rep , vol.3 , pp. 19-24
    • Burr, D.B.1
  • 12
    • 33745907255 scopus 로고    scopus 로고
    • Parathyroid hormone for the treatment of osteoporosis: A systematic review
    • Cranney A, Papaioannou A, Zytaruk N, Hanley D, Adachi J, Goltzman D, et al. Parathyroid hormone for the treatment of osteoporosis: a systematic review. CMAJ 2006;175:52-9.
    • (2006) CMAJ , vol.175 , pp. 52-59
    • Cranney, A.1    Papaioannou, A.2    Zytaruk, N.3    Hanley, D.4    Adachi, J.5    Goltzman, D.6
  • 13
    • 33644514312 scopus 로고    scopus 로고
    • Teriparatide [human PTH(1-34)]: 2.5 years of experience on the use and safety of the drug for the treatment of osteoporosis
    • Tashjian Jr AH, Gagel RF. Teriparatide [human PTH(1-34)]: 2.5 years of experience on the use and safety of the drug for the treatment of osteoporosis. J Bone Miner Res 2006;21:354-65.
    • (2006) J Bone Miner Res , vol.21 , pp. 354-365
    • Tashjian Jr, A.H.1    Gagel, R.F.2
  • 14
    • 33947504500 scopus 로고    scopus 로고
    • Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: A randomized trial
    • Greenspan SL, Bone HG, Ettinger MP, Hanley DA, Lindsay R, Zanchetta JR, et al. Effect of recombinant human parathyroid hormone (1-84) on vertebral fracture and bone mineral density in postmenopausal women with osteoporosis: a randomized trial. Ann Intern Med 2007;146:326-39.
    • (2007) Ann Intern Med , vol.146 , pp. 326-339
    • Greenspan, S.L.1    Bone, H.G.2    Ettinger, M.P.3    Hanley, D.A.4    Lindsay, R.5    Zanchetta, J.R.6
  • 15
    • 33845369453 scopus 로고    scopus 로고
    • Effects of parathyroid hormone alone or in combination with antiresorptive therapy on bone mineral density and fracture risk - a meta-analysis
    • Vestergaard P, Jorgensen NR, Mosekilde L, Schwarz P. Effects of parathyroid hormone alone or in combination with antiresorptive therapy on bone mineral density and fracture risk - a meta-analysis. Osteoporos Int 2007;18:45-57.
    • (2007) Osteoporos Int , vol.18 , pp. 45-57
    • Vestergaard, P.1    Jorgensen, N.R.2    Mosekilde, L.3    Schwarz, P.4
  • 16
    • 0030914661 scopus 로고    scopus 로고
    • Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading
    • Halloran BP, Bikle DD, Harris J, Tanner S, Curren T, Morey-Holton E. Regional responsiveness of the tibia to intermittent administration of parathyroid hormone as affected by skeletal unloading. J Bone Miner Res 1997;12:1068-74.
    • (1997) J Bone Miner Res , vol.12 , pp. 1068-1074
    • Halloran, B.P.1    Bikle, D.D.2    Harris, J.3    Tanner, S.4    Curren, T.5    Morey-Holton, E.6
  • 17
    • 16644366879 scopus 로고    scopus 로고
    • Skeletal unloading alleviates the anabolic action of intermittent PTH(1-34) in mouse tibia in association with inhibition of PTH-induced increase in c-fos mRNA in bone marrow cells
    • Tanaka S, Sakai A, Tanaka M, Otomo H, Okimoto N, Sakata T, et al. Skeletal unloading alleviates the anabolic action of intermittent PTH(1-34) in mouse tibia in association with inhibition of PTH-induced increase in c-fos mRNA in bone marrow cells. J Bone Miner Res 2004;19:1813-20.
    • (2004) J Bone Miner Res , vol.19 , pp. 1813-1820
    • Tanaka, S.1    Sakai, A.2    Tanaka, M.3    Otomo, H.4    Okimoto, N.5    Sakata, T.6
  • 18
    • 33748470774 scopus 로고    scopus 로고
    • Disuse in adult male rats attenuates the bone anabolic response to a therapeutic dose of parathyroid hormone
    • Turner RT, Lotinun S, Hefferan TE, Morey-Holton E. Disuse in adult male rats attenuates the bone anabolic response to a therapeutic dose of parathyroid hormone. J Appl Physiol 2006;101:881-6.
    • (2006) J Appl Physiol , vol.101 , pp. 881-886
    • Turner, R.T.1    Lotinun, S.2    Hefferan, T.E.3    Morey-Holton, E.4
  • 20
    • 4444222474 scopus 로고    scopus 로고
    • Is estrogen receptor alpha key to controlling bones' resistance to fracture?
    • Lanyon L, Armstrong V, Ong D, Zaman G, Price J. Is estrogen receptor alpha key to controlling bones' resistance to fracture? J Endocrinol 2004;182:183-91.
    • (2004) J Endocrinol , vol.182 , pp. 183-191
    • Lanyon, L.1    Armstrong, V.2    Ong, D.3    Zaman, G.4    Price, J.5
  • 21
    • 33746978336 scopus 로고    scopus 로고
    • One mechanostat or many? Modifications of the site-specific response of bone to mechanical loading by nature and nurture
    • Skerry TM. One mechanostat or many? Modifications of the site-specific response of bone to mechanical loading by nature and nurture. J Musculoskelet Neuronal Interact 2006;6:122-7.
    • (2006) J Musculoskelet Neuronal Interact , vol.6 , pp. 122-127
    • Skerry, T.M.1
  • 22
    • 33344455592 scopus 로고    scopus 로고
    • Molecular pathways mediating mechanical signaling in bone
    • Rubin J, Rubin C, Jacobs CR. Molecular pathways mediating mechanical signaling in bone. Gene 2006;367:1-16.
    • (2006) Gene , vol.367 , pp. 1-16
    • Rubin, J.1    Rubin, C.2    Jacobs, C.R.3
  • 23
    • 25444434346 scopus 로고    scopus 로고
    • The benefit of combining non-mechanical agents with mechanical loading: A perspective based on the Utah paradigm of skeletal physiology
    • Jee WS, Tian XY. The benefit of combining non-mechanical agents with mechanical loading: a perspective based on the Utah paradigm of skeletal physiology. J Musculoskelet Neuronal Interact 2005;5:110-8.
    • (2005) J Musculoskelet Neuronal Interact , vol.5 , pp. 110-118
    • Jee, W.S.1    Tian, X.Y.2
  • 24
    • 34248506476 scopus 로고    scopus 로고
    • Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium
    • Lindsay R, Zhou H, Cosman F, Nieves J, Dempster DW, Hodsman AB. Effects of a one-month treatment with PTH(1-34) on bone formation on cancellous, endocortical, and periosteal surfaces of the human ilium. J Bone Miner Res 2007;22:495-502.
    • (2007) J Bone Miner Res , vol.22 , pp. 495-502
    • Lindsay, R.1    Zhou, H.2    Cosman, F.3    Nieves, J.4    Dempster, D.W.5    Hodsman, A.B.6
  • 25
    • 34248544958 scopus 로고    scopus 로고
    • Skeletal actions of intermittent parathyroid hormone: Effects on bone remodelling and structure
    • Compston JE. Skeletal actions of intermittent parathyroid hormone: effects on bone remodelling and structure. Bone 2007;40:1447-52.
    • (2007) Bone , vol.40 , pp. 1447-1452
    • Compston, J.E.1
  • 26
    • 34447103537 scopus 로고    scopus 로고
    • Effects of daily treatment with parathyroid hormone 1-84 for 16 months on density, architecture and biomechanical properties of cortical bone in adult ovariectomized rhesus monkeys
    • Fox J, Miller MA, Newman MK, Recker RR, Turner CH, Smith SY. Effects of daily treatment with parathyroid hormone 1-84 for 16 months on density, architecture and biomechanical properties of cortical bone in adult ovariectomized rhesus monkeys. Bone 2007;41:321-30.
    • (2007) Bone , vol.41 , pp. 321-330
    • Fox, J.1    Miller, M.A.2    Newman, M.K.3    Recker, R.R.4    Turner, C.H.5    Smith, S.Y.6
  • 27
    • 0036050686 scopus 로고    scopus 로고
    • Effects of skeletal loading on bone mass and compensation mechanism in bone: A new insight into the qmechanostatq theory
    • Sugiyama T, Yamaguchi A, Kawai S. Effects of skeletal loading on bone mass and compensation mechanism in bone: a new insight into the qmechanostatq theory. J Bone Miner Metab 2002;20:196-200.
    • (2002) J Bone Miner Metab , vol.20 , pp. 196-200
    • Sugiyama, T.1    Yamaguchi, A.2    Kawai, S.3
  • 28
    • 34547412484 scopus 로고    scopus 로고
    • Warfarin-induced impairment of cortical bonematerial quality and compensatory adaptation of cortical bone structure to mechanical stimuli
    • Sugiyama T, Takaki T, Sakanaka K, Sadamaru H, Mori K, Kato Y, et al. Warfarin-induced impairment of cortical bonematerial quality and compensatory adaptation of cortical bone structure to mechanical stimuli. J Endocrinol 2007;194:213-22.
    • (2007) J Endocrinol , vol.194 , pp. 213-222
    • Sugiyama, T.1    Takaki, T.2    Sakanaka, K.3    Sadamaru, H.4    Mori, K.5    Kato, Y.6
  • 29
    • 0028240455 scopus 로고
    • Stimulation of signal transduction pathways in osteoblasts by mechanical strain potentiated by parathyroid hormone
    • Carvalho RS, Scott JE, Suga DM, Yen EH. Stimulation of signal transduction pathways in osteoblasts by mechanical strain potentiated by parathyroid hormone. J Bone Miner Res 1994;9:999-1011.
    • (1994) J Bone Miner Res , vol.9 , pp. 999-1011
    • Carvalho, R.S.1    Scott, J.E.2    Suga, D.M.3    Yen, E.H.4
  • 30
    • 0033873794 scopus 로고    scopus 로고
    • Parathyroid hormone modulates the response of osteoblast-like cells to mechanical stimulation
    • Ryder KD, Duncan RL. Parathyroid hormone modulates the response of osteoblast-like cells to mechanical stimulation. Calcif Tissue Int 2000;67:241-6.
    • (2000) Calcif Tissue Int , vol.67 , pp. 241-246
    • Ryder, K.D.1    Duncan, R.L.2
  • 31
    • 0028803191 scopus 로고
    • Tomographic (pQCT) and biomechanical effects of hPTH(1-38) on chronically immobilized or overloaded rat femurs
    • Capozza R, Ma YF, Ferretti JL, Meta M, Alippi R, Zanchetta J, et al. Tomographic (pQCT) and biomechanical effects of hPTH(1-38) on chronically immobilized or overloaded rat femurs. Bone 1995;17:233S-9S.
    • (1995) Bone , vol.17
    • Capozza, R.1    Ma, Y.F.2    Ferretti, J.L.3    Meta, M.4    Alippi, R.5    Zanchetta, J.6
  • 32
    • 0031934350 scopus 로고    scopus 로고
    • Role for parathyroid hormone in mechanical responsiveness of rat bone
    • Chow JW, Fox S, Jagger CJ, Chambers TJ. Role for parathyroid hormone in mechanical responsiveness of rat bone. Am J Physiol 1998;274:E146-54.
    • (1998) Am J Physiol , vol.274
    • Chow, J.W.1    Fox, S.2    Jagger, C.J.3    Chambers, T.J.4
  • 33
    • 0032970789 scopus 로고    scopus 로고
    • Parathyroid hormone and mechanical usage have a synergistic effect in rat tibial diaphyseal cortical bone
    • Ma Y, Jee WS, Yuan Z, Wei W, Chen H, Pun S, et al. Parathyroid hormone and mechanical usage have a synergistic effect in rat tibial diaphyseal cortical bone. J Bone Miner Res 1999;14:439-48.
    • (1999) J Bone Miner Res , vol.14 , pp. 439-448
    • Ma, Y.1    Jee, W.S.2    Yuan, Z.3    Wei, W.4    Chen, H.5    Pun, S.6
  • 34
    • 0034916273 scopus 로고    scopus 로고
    • Effect of parathyroid hormone on cortical bone response to in vivo external loading of the rat tibia
    • Hagino H, Okano T, Akhter MP, Enokida M, Teshima R. Effect of parathyroid hormone on cortical bone response to in vivo external loading of the rat tibia. J Bone Miner Metab 2001;19:244-50.
    • (2001) J Bone Miner Metab , vol.19 , pp. 244-250
    • Hagino, H.1    Okano, T.2    Akhter, M.P.3    Enokida, M.4    Teshima, R.5
  • 35
    • 0037387070 scopus 로고    scopus 로고
    • Parathyroid hormone enhances mechanically induced bone formation, possibly involving L-type voltage-sensitive calcium channels
    • Li J, Duncan RL, Burr DB, Gattone VH, Turner CH. Parathyroid hormone enhances mechanically induced bone formation, possibly involving L-type voltage-sensitive calcium channels. Endocrinology 2003;144:1226-33.
    • (2003) Endocrinology , vol.144 , pp. 1226-1233
    • Li, J.1    Duncan, R.L.2    Burr, D.B.3    Gattone, V.H.4    Turner, C.H.5
  • 36
    • 0344011532 scopus 로고    scopus 로고
    • Trabecular bone response to mechanical and parathyroid hormone stimulation: The role of mechanical microenvironment
    • Kim CH, Takai E, Zhou H, von Stechow D, Muller R, Dempster DW, et al. Trabecular bone response to mechanical and parathyroid hormone stimulation: the role of mechanical microenvironment. J Bone Miner Res 2003;18:2116-25.
    • (2003) J Bone Miner Res , vol.18 , pp. 2116-2125
    • Kim, C.H.1    Takai, E.2    Zhou, H.3    von Stechow, D.4    Muller, R.5    Dempster, D.W.6
  • 37
    • 0347475787 scopus 로고    scopus 로고
    • Anabolic action of parathyroid hormone on cortical and cancellous bone differs between axial and appendicular skeletal sites in mice
    • Zhou H, Iida-Klein A, Lu SS, Ducayen-Knowles M, Levine LR, Dempster DW, et al. Anabolic action of parathyroid hormone on cortical and cancellous bone differs between axial and appendicular skeletal sites in mice. Bone 2003;32:513-20.
    • (2003) Bone , vol.32 , pp. 513-520
    • Zhou, H.1    Iida-Klein, A.2    Lu, S.S.3    Ducayen-Knowles, M.4    Levine, L.R.5    Dempster, D.W.6
  • 38
  • 39
    • 33646902229 scopus 로고    scopus 로고
    • Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear
    • Lau KH, Kapur S, Kesavan C, Baylink DJ. Up-regulation of the Wnt, estrogen receptor, insulin-like growth factor-I, and bone morphogenetic protein pathways in C57BL/6J osteoblasts as opposed to C3H/HeJ osteoblasts in part contributes to the differential anabolic response to fluid shear. J Biol Chem 2006;281:9576-88.
    • (2006) J Biol Chem , vol.281 , pp. 9576-9588
    • Lau, K.H.1    Kapur, S.2    Kesavan, C.3    Baylink, D.J.4
  • 40
    • 0036756329 scopus 로고    scopus 로고
    • Validation of a technique for studying functional adaptation of the mouse ulna in response to mechanical loading
    • Lee KC, Maxwell A, Lanyon LE. Validation of a technique for studying functional adaptation of the mouse ulna in response to mechanical loading. Bone 2002;31:407-12.
    • (2002) Bone , vol.31 , pp. 407-412
    • Lee, K.C.1    Maxwell, A.2    Lanyon, L.E.3
  • 41
    • 28844442933 scopus 로고    scopus 로고
    • Noninvasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: A new model to study cortical and cancellous compartments in a single loaded element
    • De Souza RL, Matsuura M, Eckstein F, Rawlinson SC, Lanyon LE, Pitsillides AA. Noninvasive axial loading of mouse tibiae increases cortical bone formation and modifies trabecular organization: a new model to study cortical and cancellous compartments in a single loaded element. Bone 2005;37:810-8.
    • (2005) Bone , vol.37 , pp. 810-818
    • De Souza, R.L.1    Matsuura, M.2    Eckstein, F.3    Rawlinson, S.C.4    Lanyon, L.E.5    Pitsillides, A.A.6
  • 43
    • 0036239551 scopus 로고    scopus 로고
    • Anabolic action of parathyroid hormone is skeletal site specific at the tissue and cellular levels in mice
    • Iida-Klein A, Zhou H, Lu SS, Levine LR, Ducayen-Knowles M, Dempster DW, et al. Anabolic action of parathyroid hormone is skeletal site specific at the tissue and cellular levels in mice. J Bone Miner Res 2002;17:808-16.
    • (2002) J Bone Miner Res , vol.17 , pp. 808-816
    • Iida-Klein, A.1    Zhou, H.2    Lu, S.S.3    Levine, L.R.4    Ducayen-Knowles, M.5    Dempster, D.W.6
  • 44
    • 33144482005 scopus 로고    scopus 로고
    • Effects of cyclic versus daily hPTH(1-34) regimens on bone strength in association with BMD, biochemical markers, and bone structure in mice
    • Iida-Klein A, Hughes C, Lu SS, Moreno A, Shen V, Dempster DW, et al. Effects of cyclic versus daily hPTH(1-34) regimens on bone strength in association with BMD, biochemical markers, and bone structure in mice. J Bone Miner Res 2006;21:274-82.
    • (2006) J Bone Miner Res , vol.21 , pp. 274-282
    • Iida-Klein, A.1    Hughes, C.2    Lu, S.S.3    Moreno, A.4    Shen, V.5    Dempster, D.W.6
  • 45
    • 0344826782 scopus 로고    scopus 로고
    • Bone's mechanostat: A 2003 update. Anat Rec A Discov Mol Cell
    • Frost HM. Bone's mechanostat: a 2003 update. Anat Rec A Discov Mol Cell Evol Biol 2003;275:1081-101.
    • (2003) Evol Biol , vol.275 , pp. 1081-1101
    • Frost, H.M.1


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