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Volumn 153, Issue 5, 2012, Pages 2254-2266

Estrogen receptors α and β have different gender-dependent effects on the adaptive responses to load bearing in cancellous and cortical bone

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA;

EID: 84860344187     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1977     Document Type: Article
Times cited : (59)

References (64)
  • 1
    • 79957528374 scopus 로고    scopus 로고
    • Regulationof bone mass: Local control or systemic influence or both?
    • Lanyon LE, Sugiyama T, Price J 2009 Regulationof bone mass: local control or systemic influence or both? IBMS BoneKEy 6:218-226
    • (2009) IBMS BoneKEy , vol.6 , pp. 218-226
    • Lanyon, L.E.1    Sugiyama, T.2    Price, J.3
  • 2
    • 0003474880 scopus 로고
    • (Das Gesetz der Transformation der Knochen, Kirchwald). Berlin: Springer-Verlag
    • Wolff J 1892 The law of bone remodelling (Das Gesetz der Transformation der Knochen, Kirchwald). Berlin: Springer-Verlag
    • (1892) The Law of Bone Remodelling
    • Wolff, J.1
  • 3
    • 0023173665 scopus 로고
    • The mechanostat: A proposed pathogenic mechanism of osteoporoses and the bone mass effects of mechanical and nonmechanical agents
    • Frost HM 1987 The mechanostat: A proposed pathogenic mechanism of osteoporosis and the bone mass effects of mechanical and nonmechanical agents. Bone Miner 2:73-85 (Pubitemid 17119417)
    • (1987) Bone and Mineral , vol.2 , Issue.2 , pp. 73-85
    • Frost, H.M.1
  • 4
    • 0023492075 scopus 로고
    • Bone "Mass" and the "mechanostat": A proposal
    • Frost HM 1987 Bone "mass" and the "mechanostat": a proposal. Anat Rec 219:1-9
    • (1987) Anat Rec , vol.219 , pp. 1-9
    • Frost, H.M.1
  • 5
    • 23944475651 scopus 로고    scopus 로고
    • Estrogen, androgen, and the pathogenesis of bone fragility in women and men
    • Seeman E 2004 Estrogen, androgen, and the pathogenesis of bone fragility in women and men. Curr Osteoporos Rep 2:90-96
    • (2004) Curr Osteoporos Rep , vol.2 , pp. 90-96
    • Seeman, E.1
  • 6
    • 84942948140 scopus 로고
    • Postmenopausal osteoporosis: Its clinical features
    • Albright F, Smith PH, Richardson AM 1941 Postmenopausal osteoporosis: its clinical features. J Am Med Assoc 116:2465-2474
    • (1941) J Am Med Assoc , vol.116 , pp. 2465-2474
    • Albright, F.1    Smith, P.H.2    Richardson, A.M.3
  • 7
    • 0032806102 scopus 로고    scopus 로고
    • Reproductive phenotypes in the estrogen receptor-α knockout mouse
    • Couse, J.F. and K.S. Korach, 1999 Reproductive phenotypes in the estrogen receptor - a knockout mouse. Ann Endocrinol (Paris) 60: 143-148 (Pubitemid 29359907)
    • (1999) Annales d'Endocrinologie , vol.60 , Issue.2 , pp. 143-148
    • Couse, J.F.1    Korach, K.S.2
  • 8
    • 0033791733 scopus 로고    scopus 로고
    • Mechanical strain stimulates osteoblast proliferation through estrogen receptor in males as well as females
    • Damien E, Price JS, Lanyon LE 2000 Mechanical strain stimulates osteoblast proliferation through estrogen receptor in males as well as females. J Bone Miner Res 15:2169-2177
    • (2000) J Bone Miner Res , vol.15 , pp. 2169-2177
    • Damien, E.1    Price, J.S.2    Lanyon, L.E.3
  • 9
    • 0031859351 scopus 로고    scopus 로고
    • The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain
    • DOI 10.1359/jbmr.1998.13.8.1275
    • Damien E, Price JS, Lanyon LE 1998 The estrogen receptor's involvement in osteoblasts' adaptive response to mechanical strain. J Bone Miner Res 13:1275-1282 (Pubitemid 28373329)
    • (1998) Journal of Bone and Mineral Research , vol.13 , Issue.8 , pp. 1275-1282
    • Damien, E.1    Price, J.S.2    Lanyon, L.E.3
  • 10
    • 0042265549 scopus 로고    scopus 로고
    • Bone adaptation requires oestrogen receptor-α
    • Lee K, Jessop H, Suswillo R, Zaman G, Lanyon L 2003 Endocrinology: bone adaptation requires oestrogen receptor - α. Nature 424: 389 (Pubitemid 36917478)
    • (2003) Nature , vol.424 , Issue.6947 , pp. 389
    • Lee, K.1    Jessop, H.2    Suswillo, R.3    Zaman, G.4    Lanyon, L.5
  • 11
    • 4444314796 scopus 로고    scopus 로고
    • The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-α and -β
    • DOI 10.1677/joe.0.1820193
    • Lee KC, Jessop H, Suswillo R, Zaman G, Lanyon LE 2004 The adaptive response of bone to mechanical loading in female transgenic mice is deficient in the absence of oestrogen receptor-α and -β. J Endocrinol 182:193-201 (Pubitemid 39199003)
    • (2004) Journal of Endocrinology , vol.182 , Issue.2 , pp. 193-201
    • Lee, K.C.L.1    Jessop, H.2    Suswillo, R.3    Zaman, G.4    Lanyon, L.E.5
  • 13
    • 77649181032 scopus 로고    scopus 로고
    • Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor a and disuse
    • Zaman G, Saxon LK, Sunters A, Hilton H, Underhill P, Williams D, Price JS, Lanyon LE 2010 Loading-related regulation of gene expression in bone in the contexts of estrogen deficiency, lack of estrogen receptor a and disuse. Bone 46:628-642
    • (2010) Bone , vol.46 , pp. 628-642
    • Zaman, G.1    Saxon, L.K.2    Sunters, A.3    Hilton, H.4    Underhill, P.5    Williams, D.6    Price, J.S.7    Lanyon, L.E.8
  • 14
    • 74249114163 scopus 로고    scopus 로고
    • Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones
    • Sugiyama T, Price JS, Lanyon LE 2010 Functional adaptation to mechanical loading in both cortical and cancellous bone is controlled locally and is confined to the loaded bones. Bone 46:314-321
    • (2010) Bone , vol.46 , pp. 314-321
    • Sugiyama, T.1    Price, J.S.2    Lanyon, L.E.3
  • 21
    • 18044380306 scopus 로고    scopus 로고
    • Genetic and environmental determinants of bone mineral density in Chinese women
    • DOI 10.1016/j.bone.2005.01.014
    • Lau HH, Ng MY, Ho AY, Luk KD, Kung AW 2005 Genetic and environmental determinants of bone mineral density in Chinese women. Bone 36:700-709 (Pubitemid 40602264)
    • (2005) Bone , vol.36 , Issue.4 , pp. 700-709
    • Lau, H.H.L.1    Ng, M.Y.M.2    Ho, A.Y.Y.3    Luk, K.D.K.4    Kung, A.W.C.5
  • 22
    • 0037383154 scopus 로고    scopus 로고
    • Aerobic exercise and bone mineral density in middle-aged Finnish men: A controlled randomized trial with reference to androgen receptor, aromatase, and estrogen receptor α gene polymorphisms
    • DOI 10.1016/S8756-3282(03)00032-2
    • Remes T, Väisänen SB, Mahonen A, Huuskonen J, Kröger H, Jurvelin JS, Penttilä IM, Rauramaa R 2003 Aerobic exercise and bone mineral density in middle-aged finnish men: a controlled randomized trial with reference to androgen receptor, aromatase, and estrogen receptor a gene polymorphisms. Bone 32:412-420 (Pubitemid 36407542)
    • (2003) Bone , vol.32 , Issue.4 , pp. 412-420
    • Remes, T.1    Vaisanen, S.B.2    Mahonen, A.3    Huuskonen, J.4    Kroger, H.5    Jurvelin, J.S.6    Penttila, I.M.7    Rauramaa, R.8
  • 23
    • 78449276562 scopus 로고    scopus 로고
    • Oestrogen receptor - A polymorphism and risk of fracture: A meta-analysis of 13 studies including 1279 cases and 6069 controls
    • Lei MM, Yang TF, Tu ZQ, Liu L, Fang Y, Wang GL 2010 Oestrogen receptor - a polymorphism and risk of fracture: a meta-analysis of 13 studies including 1279 cases and 6069 controls. J Int Med Res 38: 1575-1583
    • (2010) J Int Med Res , vol.38 , pp. 1575-1583
    • Lei, M.M.1    Yang, T.F.2    Tu, Z.Q.3    Liu, L.4    Fang, Y.5    Wang, G.L.6
  • 28
    • 0037314762 scopus 로고    scopus 로고
    • Estrogen receptor (ER)-β reduces ERα-regulated gene transcription, supporting a "Ying Yang" relationship between ERα and ERβ in mice
    • DOI 10.1210/me.2002-0206
    • Lindberg MK, Movérare S, Skrtic S, Gao H, Dahlman-Wright K, Gustafsson JA, Ohlsson C 2003 Estrogen receptor (ER)-β reduces ERa-regulated gene transcription, supporting a "ying yang" relationship between ERα and ERβ in mice. Mol Endocrinol 17:203-208 (Pubitemid 36187395)
    • (2003) Molecular Endocrinology , vol.17 , Issue.2 , pp. 203-208
    • Lindberg, M.K.1    Moverare, S.2    Skrtic, S.3    Gao, H.4    Dahlman-Wright, K.5    Gustafsson, J.-A.6    Ohlsson, C.7
  • 29
    • 33749531907 scopus 로고    scopus 로고
    • T-1213C polymorphism of estrogen receptor beta is associated with low bone mineral density and osteoporotic fractures
    • DOI 10.1016/j.bone.2006.04.029, PII S8756328206004777
    • Kung AW, Lai BM, Ng MY, Chan V, Sham PC 2006 T-1213C polymorphism of estrogen receptor β is associated with low bone mineral density and osteoporotic fractures. Bone 39:1097-1106 (Pubitemid 44528372)
    • (2006) Bone , vol.39 , Issue.5 , pp. 1097-1106
    • Kung, A.W.C.1    Lai, B.M.H.2    Ng, M.Y.M.3    Chan, V.4    Sham, P.C.5
  • 32
    • 0036021054 scopus 로고    scopus 로고
    • Estrogen receptor β gene polymorphisms are associated with higher bone mineral density in premenopausal, but not postmenopausal southern Chinese women
    • DOI 10.1016/S8756-3282(02)00827-X, PII S875632820200827X
    • Lau HH, Ho AY, Luk KD, Kung AW 2002 Estrogen receptor β gene polymorphisms are associated with higher bone mineral density in premenopausal, but not postmenopausal southern Chinese women. Bone 31:276-281 (Pubitemid 34814961)
    • (2002) Bone , vol.31 , Issue.2 , pp. 276-281
    • Lau, H.H.L.1    Ho, A.Y.Y.2    Luk, K.D.K.3    Kung, A.W.C.4
  • 33
    • 2942633601 scopus 로고    scopus 로고
    • Estrogen receptor β dinucleotide (CA) repeat polymorphism is significantly associated with bone mineral density in postmenopausal women
    • DOI 10.1007/s00223-003-0170-x
    • Scariano JK, Simplicio SG, Montoya GD, Garry PJ, Baumgartner RN 2004 Estrogen receptor β dinucleotide (CA) repeat polymorphism is significantly associated with bone mineral density in postmenopausal women. Calcif Tissue Int 74:501-508 (Pubitemid 38780285)
    • (2004) Calcified Tissue International , vol.74 , Issue.6 , pp. 501-508
    • Scariano, J.K.1    Simplicio, S.G.2    Montoya, G.D.3    Garry, P.J.4    Baumgartner, R.N.5
  • 36
    • 0036919257 scopus 로고    scopus 로고
    • Down but not out? A novel protein isoform of the estrogen receptor α is expressed in the estrogen receptor α knockout mouse
    • DOI 10.1677/jme.0.0290281
    • Kos M, Denger S, Reid G, Korach KS, Gannon F 2002 Down but not out? A novel protein isoform of the estrogen receptor α is expressed in the estrogen receptor α knockout mouse. J Mol Endocrinol 29: 281-286 (Pubitemid 36024544)
    • (2002) Journal of Molecular Endocrinology , vol.29 , Issue.3 , pp. 281-286
    • Kos, M.1    Denger, S.2    Reid, G.3    Korach, K.S.4    Gannon, F.5
  • 37
    • 0033767836 scopus 로고    scopus 로고
    • Effect of single and compound knockouts of estrogen receptors α (ERa) and β (ERβ) on mouse reproductive phenotypes
    • Dupont S, Krust A, Gansmuller A, Dierich A, Chambon P, Mark M 2000 Effect of single and compound knockouts of estrogen receptors α (ERa) and β (ERβ) on mouse reproductive phenotypes. Development 127:4277-4291
    • (2000) Development , vol.127 , pp. 4277-4291
    • Dupont, S.1    Krust, A.2    Gansmuller, A.3    Dierich, A.4    Chambon, P.5    Mark, M.6
  • 38
    • 52449085471 scopus 로고    scopus 로고
    • Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice
    • Sugiyama T, Saxon LK, Zaman G, Moustafa A, Sunters A, Price JS, Lanyon LE 2008 Mechanical loading enhances the anabolic effects of intermittent parathyroid hormone (1-34) on trabecular and cortical bone in mice. Bone 43:238-248
    • (2008) Bone , vol.43 , pp. 238-248
    • Sugiyama, T.1    Saxon, L.K.2    Zaman, G.3    Moustafa, A.4    Sunters, A.5    Price, J.S.6    Lanyon, L.E.7
  • 43
    • 0037020144 scopus 로고    scopus 로고
    • Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor α
    • Kos M, Denger S, Reid G, Gannon F 2002 Upstream open reading frames regulate the translation of the multiple mRNA variants of the estrogen receptor α. J Biol Chem 277:37131-37138
    • (2002) J Biol Chem , vol.277 , pp. 37131-37138
    • Kos, M.1    Denger, S.2    Reid, G.3    Gannon, F.4
  • 45
    • 79958765106 scopus 로고    scopus 로고
    • Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor α on bone
    • Syed FA, Fraser DG, Monroe DG, Khosla S 2011 Distinct effects of loss of classical estrogen receptor signaling versus complete deletion of estrogen receptor α on bone. Bone 49:208-216
    • (2011) Bone , vol.49 , pp. 208-216
    • Syed, F.A.1    Fraser, D.G.2    Monroe, D.G.3    Khosla, S.4
  • 46
    • 0036139736 scopus 로고    scopus 로고
    • Growth rate rather than gender determines the size of the adaptive response of the growing skeleton to mechanical strain
    • DOI 10.1016/S8756-3282(01)00626-3, PII S8756328201006263
    • Mosley JR, Lanyon LE 2002 Growth rate rather than gender determines the size of the adaptive response of the growing skeleton to mechanical strain. Bone 30:314-319 (Pubitemid 34044333)
    • (2002) Bone , vol.30 , Issue.1 , pp. 314-319
    • Mosley, J.R.1    Lanyon, L.E.2
  • 48
    • 0035016058 scopus 로고    scopus 로고
    • The effects of oestrogens on linear bone growth
    • DOI 10.1093/humupd/7.3.303
    • Juul A 2001 The effects of oestrogens on linear bone growth. Hum Reprod Update 7:303-313 (Pubitemid 32440292)
    • (2001) Human Reproduction Update , vol.7 , Issue.3 , pp. 303-313
    • Juul, A.1
  • 49
    • 0034749898 scopus 로고    scopus 로고
    • Minireview: Aromatase and the regulation of estrogen biosynthesis - Some new perspectives
    • DOI 10.1210/en.142.11.4589
    • Simpson ER, Davis SR 2001 Aromatase and the regulation of estrogen biosynthesis: some new perspectives. Endocrinology 142: 4589-4594 (Pubitemid 33022332)
    • (2001) Endocrinology , vol.142 , Issue.11 , pp. 4589-4594
    • Simpson, E.R.1    Davis, S.R.2
  • 54
    • 0036139964 scopus 로고    scopus 로고
    • Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males
    • DOI 10.1016/S8756-3282(01)00643-3, PII S8756328201006433
    • Sims NA, Dupont S, Krust A, Clement-Lacroix P, Minet D, Resche-Rigon M, Gaillard-Kelly M, Baron R 2002 Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males. Bone 30:18-25 (Pubitemid 34044296)
    • (2002) Bone , vol.30 , Issue.1 , pp. 18-25
    • Sims, N.A.1    Dupont, S.2    Krust, A.3    Clement-Lacroix, P.4    Minet, D.5    Resche-Rigon, M.6    Gaillard-Kelly, M.7    Baron, R.8
  • 63
    • 34547111836 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α
    • DOI 10.1074/jbc.M703224200
    • Armstrong VJ, Muzylak M, Sunters A, Zaman G, Saxon LK, Price JS, Lanyon LE 2007 Wnt/β-catenin signaling is a component of osteoblastic bone cell early responses to load-bearing and requires estrogen receptor α. J Biol Chem 282:20715-20727 (Pubitemid 47100049)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.28 , pp. 20715-20727
    • Armstrong, V.J.1    Muzylak, M.2    Sunters, A.3    Zaman, G.4    Saxon, L.K.5    Price, J.S.6    Lanyon, L.E.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.