The effect of pH on PAMAM dendrimer-siRNA complexation - Endosomal considerations as determined by molecular dynamics simulation

Biophysical Chemistry

Volumn 158, Issue 2-3, 2011, Pages 126-133

  Ouyang, Defang ^a   Zhang, Hong ^b   Parekh, Harendra S ^b   Smith, Sean C ^b  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Dendrimer; Endosome; Gene delivery; Molecular dynamics simulation; Proton sponge theory; siRNA

Indexed keywords

DENDRIMER; POLYAMIDOAMINE; SMALL INTERFERING RNA;

ARTICLE; COMPLEX FORMATION; ENDOSOME; MOLECULAR DYNAMICS; PH; PRIORITY JOURNAL;

DENDRIMERS; HYDROGEN-ION CONCENTRATION; MOLECULAR DYNAMICS SIMULATION; POLYAMINES; RNA, SMALL INTERFERING; THERMODYNAMICS;

EID: 79960707221     PISSN: 03014622     EISSN: 18734200     Source Type: Journal    
DOI: 10.1016/j.bpc.2011.06.003     Document Type: Article

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