Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling

Journal of Biological Chemistry

Volumn 288, Issue 1, 2013, Pages 181-191

  Schellekens, Harriët ^a,b   Van Oeffelen, Wesley E P A ^a   Dinan, Timothy G ^a,b   Cryan, John F ^a,b  

^a UNIVERSITY COLLEGE CORK   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM INFLUX; DRUG TARGETS; FOOD INTAKE; G PROTEIN COUPLED RECEPTORS; GHRELIN; GHRELIN RECEPTOR; GROWTH HORMONES; GUT PEPTIDES; HETERODIMERIZATION; HETERODIMERS; HOMEOSTATIC CONTROL; HOMEOSTATIC REGULATIONS; ISOFORMS; PHARMACOLOGICAL BLOCKADE;

BIOMOLECULES; DIMERIZATION; ENERGY BALANCE; NUTRITION; PROTEINS;

SIGNALING;

8 [5 [2,4 DIMETHOXY 5 (4 TRIFLUOROMETHYLPHENYLSULFONAMIDO)PHENYL] 5 OXOPENTYL] 1,3,8 TRIAZASPIRO[4.5]DECANE 2,4 DIONE; DOPAMINE 1 RECEPTOR; G PROTEIN COUPLED RECEPTOR; GHRELIN; GHRELIN RECEPTOR; HETERODIMER; IBUTAMOREN; ISOPROTEIN; MELANOCORTIN 3 RECEPTOR; SEROTONIN 2C INI RECEPTOR; SEROTONIN 2C RECEPTOR; SEROTONIN 2C VSV RECEPTOR; UNCLASSIFIED DRUG;

ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DIMERIZATION; ENERGY BALANCE; FOOD INTAKE; HUMAN; HUMAN CELL; INTERNALIZATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN HOMEOSTASIS; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; PROTEIN TRANSPORT; REWARD; SIGNAL TRANSDUCTION;

CALCIUM; DIMERIZATION; EATING; FEEDING BEHAVIOR; GENE EXPRESSION REGULATION; GHRELIN; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HOMEOSTASIS; HUMANS; LIGANDS; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; PROTEIN ISOFORMS; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, GHRELIN; SIGNAL TRANSDUCTION;

VESICULAR STOMATITIS VIRUS;

EID: 84872064517     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.382473     Document Type: Article

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