Absorption and brain penetration of a high affinity, highly selective 5-HT(2C) receptor antagonist, RS-102221

Annals of the New York Academy of Sciences

Volumn 861, Issue , 1998, Pages 269-

  Bonhaus, D W ^a   Rocha, C L ^a   Dawson, M W ^a   Eglen, R M ^a  

^a ROCHE BIOSCIENCE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 [4 (5 AMINO 2,4 DIMETHOXYBENZOYL)BUTYL] 1,3,8 TRIAZASPIRO[4.5]DECANE 2,4 DIONE; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG;

CONFERENCE PAPER; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG PENETRATION; HUMAN; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; ORAL DRUG ADMINISTRATION; RECEPTOR AFFINITY;

EID: 0032430640     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1998.tb10218.x     Document Type: Conference Paper

References (3)

1. 1. HOYER, D., D. E. CLARKE, J. R. FOZARD, P. R. HARTIG, G. R. MARTIN, E. J. MYLECHARANE, P. R. SAXENA & P. A. HUMPHREY. 1994. Pharmacol. Rev. 46: 157-203.
2. 2. WEINHARDT, K. K., D. W. BONHAUS & A. DE SOUZA. 1996. Bioorganics Med. Chem. Letts. 6: 2687-2692.
3. 3. BONHAUS, D. W., K. K. WEINHARDT, M. TAYLOR, A. DESOUZA, P. M. MCNEELLEY, K. SZCZEPANSKI, D. J. FONTANA, J. TRINH, C. L. ROCHA, M. W. DAWSON, L. A. FLIPPIN & R. M. EGLEN. 1997. Neuropharmacology 36: 621-629.