Effects of ghrelin and amylin on dopamine, norepinephrine and serotonin release in the hypothalamus

European Journal of Pharmacology

Volumn 454, Issue 2-3, 2002, Pages 189-192

  Brunetti, Luigi ^a   Recinella, Lucia ^a   Orlando, Giustino ^a   Michelotto, Barbara ^a   Di Nisio, Chiara ^a   Vacca, Michele ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); Amylin; Dopamine; Ghrelin; Hypothalamus; Norepinephrine

Indexed keywords

AMYLIN; DOPAMINE; GHRELIN; NORADRENALIN; SEROTONIN; AMYLOID; PEPTIDE HORMONE;

ANIMAL TISSUE; ANOREXIA; APPETITE; ARTICLE; CONTROLLED STUDY; DOPAMINE RELEASE; HORMONE ACTION; HYPOTHALAMUS; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SEROTONIN RELEASE; SYNAPTOSOME; ANIMAL; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SECRETION; WISTAR RAT;

AMYLOID; ANIMALS; DOPAMINE; HYPOTHALAMUS; MALE; NOREPINEPHRINE; PEPTIDE HORMONES; RATS; RATS, WISTAR; SEROTONIN;

EID: 0037111181     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(02)02552-9     Document Type: Article

References (24)

1. Banks W.A., Kastin A.J. Differential permeability of the blood-brain barrier to two pancreatic peptides: insulin and amylin. Peptides. 19:1998;883-889.
2. Banks W.A., Kastin A.J., Maness L.M., Huang W., Jaspan J.B. Permeability of the blood-brain barrier to amylin. Life Sci. 57:1995;1993-2001.
3. Brunetti L., Michelotto B., Orlando G., Vacca M. Leptin inhibits norepinephrine and dopamine release from rat hypothalamic neuronal endings. Eur. J. Pharmacol. 372:1999;237-240.
4. Brunetti L., Orlando G., Michelotto B., Recinella L., Vacca M. Cocaine- and amphetamine-regulated transcript peptide-(55-102) and thyrotropin releasing hormone inhibit hypothalamic dopamine release. Eur. J. Pharmacol. 409:2000;103-107.
5. Chance W.T., Balasubramaniam A., Stallion A., Fischer J.E. Anorexia following the systemic injection of amylin. Brain Res. 607:1991;185-188.
6. Davis R., Faulds D. Dexfenfluramine. An updated review of its therapeutic use in the management of obesity. Drugs. 52:1996;696-724.
7. D'Este L., Wimalawansa S.J., Renda T.G. Distribution of amylin-immunoreactive neurons in the monkey hypothalamus and their relationships with the histaminergic system. Arch. Histol. Cytol. 64:2001;295-303.
8. Gillard E.R., Dang D.Q., Stanley B.G. Evidence that neuropeptide Y and dopamine in the perifornical hypothalamus interact antagonistically in the control of food intake. Brain Res. 628:1993;128-136.
9. Kalra S.P., Dube M.G., Pu S., Xu B., Horvath T.L., Kalra P.S. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 20:1999;68-100.
10. Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature. 402:1999;656-660.
11. Leibowitz S.F., Alexander J.T. Hypothalamic serotonin in control of eating behavior, meal size, and body weight. Biol. Psychiatry. 44:1998;851-864.
12. Ludvik B., Kautzky-Willer A., Prager R., Thomaseth K., Pacini G. Amylin: history and overview. Diabet. Med. 14:1997;S9-S13.
13. 2 receptors mediate amylin's acute satiety effect. Am. J. Physiol., Regul. Integr. Comp. Physiol. 280:2001;R1697-R1703.
14. Nakazato M., Murakami N., Date Y., Kojima M., Matsuo H., Kangawa K., Matsukura S. A role for ghrelin in the central regulation of feeding. Nature. 409:2001;194-198.
15. Orlando G., Brunetti L., Di Nisio C., Michelotto B., Recinella L., Ciabattoni G., Vacca M. Effects of cocaine- and amphetamine-regulated transcript peptide, leptin, and orexins on hypothalamic serotonin release. Eur. J. Pharmacol. 430:2001;269-272.
16. Robbins T.W., Everitt B.J. Neurobehavioural mechanisms of reward and motivation. Curr. Opin. Neurobiol. 6:1996;228-236.
17. Rushing P.A., Hagan M.M., Seeley R.J., Lutz T.A., Woods S.C. Amylin: a novel action in the brain to reduce body weight. Endocrinology. 850:2000;850-853.
18. Samanin R., Garattini S. Neurochemical mechanisms of action of anorectic drugs. Pharmacol. Toxicol. 73:1993;63-68.
19. Shintani M., Ogawa Y., Ebihara K., Aizawa-Abe M., Miyanaga F., Takaya K., Hayashi T., Inoue G., Hosoda K., Kojima M., Kangawa K., Nakao K. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway. Diabetes. 50:2001;227-232.
20. ob/ob mice. Nat. Genet. 25:2000;102-104.
21. Tschop M., Smiley D.L., Heiman M.L. Ghrelin induces adiposity in rodents. Nature. 407:2000;908-913.
22. 2-adrenergic receptors. Life Sci. 53:1993;669-679.
23. Wren A.M., Small C.J., Abbott C.R., Dhillo W.S., Seal L.J., Cohen M.A., Batterham L.R., Taheri S., Stanley S.A., Ghatei M.A., Bloom S.R. Ghrelin causes hyperphagia and obesity in rats. Diabetes. 50:2001;2540-2547.
24. Yang Z.J., Meguid M.M. LHA dopamine activity in obese and Zucker rats. NeuroReport. 6:1995;1191-1194.