메뉴 건너뛰기




Volumn 21, Issue 1, 2013, Pages 1-12

Quinoline: A versatile heterocyclic

Author keywords

Biological activity; Quinoline; Synthesis

Indexed keywords

CARDIOTONIC AGENT; QUINOLINE;

EID: 84871997171     PISSN: 13190164     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsps.2012.03.002     Document Type: Review
Times cited : (390)

References (75)
  • 1
    • 24344486053 scopus 로고    scopus 로고
    • Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents
    • Abadi A.H., Hegazy G.H., Zaher A.A.E. Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents. Bioorg. Med. Chem. 2005, 13:5759-5765.
    • (2005) Bioorg. Med. Chem. , vol.13 , pp. 5759-5765
    • Abadi, A.H.1    Hegazy, G.H.2    Zaher, A.A.E.3
  • 2
    • 52949150116 scopus 로고    scopus 로고
    • Synthesis and antimalarial evaluation of novel pyridine quinoline hybrids
    • Acharya B.N., Thavaselvam D., Kaushik M.B. Synthesis and antimalarial evaluation of novel pyridine quinoline hybrids. Med. Chem. Res. 2008, 17:487-494.
    • (2008) Med. Chem. Res. , vol.17 , pp. 487-494
    • Acharya, B.N.1    Thavaselvam, D.2    Kaushik, M.B.3
  • 3
    • 0346264753 scopus 로고    scopus 로고
    • 3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors
    • Assefa H., Kamath S., Buolamwini J.K. 3D-QSAR and docking studies on 4-anilinoquinazoline and 4-anilinoquinoline epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors. J. Comput. Aided Mol. Des. 2003, 17:475-493.
    • (2003) J. Comput. Aided Mol. Des. , vol.17 , pp. 475-493
    • Assefa, H.1    Kamath, S.2    Buolamwini, J.K.3
  • 4
    • 0030450411 scopus 로고    scopus 로고
    • Studies on disease modifying antirheumatic drugs: synthesis of novel quinoline and quinazoline derivatives and their anti-inflammatory effect
    • Baba A., Kawamura N., Makino H., Ohta Y., Taketomi S., Sohda T. Studies on disease modifying antirheumatic drugs: synthesis of novel quinoline and quinazoline derivatives and their anti-inflammatory effect. J. Med. Chem. 1996, 39:5176-5182.
    • (1996) J. Med. Chem. , vol.39 , pp. 5176-5182
    • Baba, A.1    Kawamura, N.2    Makino, H.3    Ohta, Y.4    Taketomi, S.5    Sohda, T.6
  • 5
    • 77954331097 scopus 로고    scopus 로고
    • Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper complexing properties
    • Bachiller M.I.F., Perez C., Munoz G.C.G., Conde S., Lopez M.G., Villarroya M., Garcia A.G., Franco M.I.R. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper complexing properties. J. Med. Chem. 2010, 53:4927-4937.
    • (2010) J. Med. Chem. , vol.53 , pp. 4927-4937
    • Bachiller, M.I.F.1    Perez, C.2    Munoz, G.C.G.3    Conde, S.4    Lopez, M.G.5    Villarroya, M.6    Garcia, A.G.7    Franco, M.I.R.8
  • 6
    • 77954331097 scopus 로고    scopus 로고
    • Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties
    • Bachiller M.I.F., Perez C., Munoz G.C.G., Conde S., Lopez M.G., Villarroya M., Garcia A.G., Franco M.I.R. Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties. J. Med. Chem. 2010, 53:4927-4937.
    • (2010) J. Med. Chem. , vol.53 , pp. 4927-4937
    • Bachiller, M.I.F.1    Perez, C.2    Munoz, G.C.G.3    Conde, S.4    Lopez, M.G.5    Villarroya, M.6    Garcia, A.G.7    Franco, M.I.R.8
  • 9
    • 0000039703 scopus 로고    scopus 로고
    • Synthesis and structure activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site
    • Cai S.X., Zhou Z.L., Huang J.C., Whittemore E.R., Egbuwoku Z.O., Lu Y., Hawkinson J.E., Woodward R.M., Weber E., Keana J.F.W. Synthesis and structure activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site. J. Med. Chem. 1996, 39:3248-3255.
    • (1996) J. Med. Chem. , vol.39 , pp. 3248-3255
    • Cai, S.X.1    Zhou, Z.L.2    Huang, J.C.3    Whittemore, E.R.4    Egbuwoku, Z.O.5    Lu, Y.6    Hawkinson, J.E.7    Woodward, R.M.8    Weber, E.9    Keana, J.F.W.10
  • 10
    • 35348923059 scopus 로고    scopus 로고
    • Synthesis and HMG CoA reductase inhibition of 4-thiophenyl quinolines as potential hypocholesterolemic agents
    • Cai Z., Zhou W., Sun L. Synthesis and HMG CoA reductase inhibition of 4-thiophenyl quinolines as potential hypocholesterolemic agents. Bioorg. Med. Chem. 2007, 15:7809-7829.
    • (2007) Bioorg. Med. Chem. , vol.15 , pp. 7809-7829
    • Cai, Z.1    Zhou, W.2    Sun, L.3
  • 11
    • 61349138873 scopus 로고    scopus 로고
    • Design, synthesis, and biological evaluation of novel quinoline derivatives as HIV-1 Tat-TAR interaction inhibitors
    • Chen S., Chen R., He M., Pang R., Tan Z., Yang M. Design, synthesis, and biological evaluation of novel quinoline derivatives as HIV-1 Tat-TAR interaction inhibitors. Bioorg. Med. Chem. 2009, 17:1948-1956.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 1948-1956
    • Chen, S.1    Chen, R.2    He, M.3    Pang, R.4    Tan, Z.5    Yang, M.6
  • 12
    • 33646565358 scopus 로고    scopus 로고
    • Synthesis, cytotoxicity, and antiinflammatory evaluation of 2-(furan-2-yl)-4-(phenoxy)quinoline derivatives. Part 4
    • Chen Y., Zhao Y., Lu C., Tzeng C., Wang J.P. Synthesis, cytotoxicity, and antiinflammatory evaluation of 2-(furan-2-yl)-4-(phenoxy)quinoline derivatives. Part 4. Bioorg. Med. Chem. 2006, 14:4373-4378.
    • (2006) Bioorg. Med. Chem. , vol.14 , pp. 4373-4378
    • Chen, Y.1    Zhao, Y.2    Lu, C.3    Tzeng, C.4    Wang, J.P.5
  • 13
    • 0034609168 scopus 로고    scopus 로고
    • New amine and urea analogs of ferrochloroquine: synthesis, antimalarial activity in vitro and electrochemical studies
    • Chibale K., Moss J.R., Blackie M., Schalkwyk D., Smith P.J. New amine and urea analogs of ferrochloroquine: synthesis, antimalarial activity in vitro and electrochemical studies. Tetrahedron Lett. 2000, 41:6231-6235.
    • (2000) Tetrahedron Lett. , vol.41 , pp. 6231-6235
    • Chibale, K.1    Moss, J.R.2    Blackie, M.3    Schalkwyk, D.4    Smith, P.J.5
  • 14
    • 0034698708 scopus 로고    scopus 로고
    • Synthesis and evaluation of quinoline carboxyguanidines as antidiabetic agents
    • Edmont D., Rocher R., Plisson C., Chenault J. Synthesis and evaluation of quinoline carboxyguanidines as antidiabetic agents. Bioorg. Med. Chem. Lett. 2000, 10:1831-1834.
    • (2000) Bioorg. Med. Chem. Lett. , vol.10 , pp. 1831-1834
    • Edmont, D.1    Rocher, R.2    Plisson, C.3    Chenault, J.4
  • 15
    • 77954313777 scopus 로고    scopus 로고
    • New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties
    • Eswaran S., Adhikari A.V., Chowdhury I.H., Pal N.K., Thomas K.D. New quinoline derivatives: synthesis and investigation of antibacterial and antituberculosis properties. Eur. J. Med. Chem. 2010, 45:3374-3383.
    • (2010) Eur. J. Med. Chem. , vol.45 , pp. 3374-3383
    • Eswaran, S.1    Adhikari, A.V.2    Chowdhury, I.H.3    Pal, N.K.4    Thomas, K.D.5
  • 17
    • 0242266523 scopus 로고    scopus 로고
    • Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections
    • Fakhfakh M.A., Fournet A., Prina E., Mouscadet J.F., Franck X., Hocquemiller R., Figadere B. Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections. Bioorg. Med. Chem. 2003, 11:5013-5023.
    • (2003) Bioorg. Med. Chem. , vol.11 , pp. 5013-5023
    • Fakhfakh, M.A.1    Fournet, A.2    Prina, E.3    Mouscadet, J.F.4    Franck, X.5    Hocquemiller, R.6    Figadere, B.7
  • 20
    • 77249102563 scopus 로고    scopus 로고
    • Unexpected domino reaction via Pd-catalysed sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and cyclization to synthesize quinoline derivatives
    • Gao G.L., Niu Y.N., Yan Z.Y., Wang H.L., Wang G.W., Shaukat A., Liang Y.M. Unexpected domino reaction via Pd-catalysed sonogashira coupling of benzimidoyl chlorides with 1,6-enynes and cyclization to synthesize quinoline derivatives. J. Org. Chem. 2010, 75:1305-1308.
    • (2010) J. Org. Chem. , vol.75 , pp. 1305-1308
    • Gao, G.L.1    Niu, Y.N.2    Yan, Z.Y.3    Wang, H.L.4    Wang, G.W.5    Shaukat, A.6    Liang, Y.M.7
  • 21
    • 57549083783 scopus 로고    scopus 로고
    • Friedländer synthesis of poly-substituted quinolines in the presence of dodecylphosphonic acid (DPA) as a highly efficient, recyclable and novel catalyst in aqueous media and solvent-free conditions
    • Ghassamipour S., Sardarian A.R. Friedländer synthesis of poly-substituted quinolines in the presence of dodecylphosphonic acid (DPA) as a highly efficient, recyclable and novel catalyst in aqueous media and solvent-free conditions. Tetrahedron Lett. 2009, 50:514-519.
    • (2009) Tetrahedron Lett. , vol.50 , pp. 514-519
    • Ghassamipour, S.1    Sardarian, A.R.2
  • 22
    • 34548542570 scopus 로고    scopus 로고
    • Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and its analogues
    • Gholap A.R., Toti K.S., Shirazi F., Kumari R., Bhat M.K., Deshpande M.V., Srinivasan K.V. Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and its analogues. Bioorg. Med. Chem. 2007, 15:6705-6715.
    • (2007) Bioorg. Med. Chem. , vol.15 , pp. 6705-6715
    • Gholap, A.R.1    Toti, K.S.2    Shirazi, F.3    Kumari, R.4    Bhat, M.K.5    Deshpande, M.V.6    Srinivasan, K.V.7
  • 23
    • 50549100383 scopus 로고    scopus 로고
    • Therapeutic effect of a novel anilidoquinoline derivative, 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, in Japanese encephalitis: correlation with in vitro neuroprotection
    • Ghosh J, Swarup V, Saxena A, Das S, Hazra A, Paira P, Banerjee S, Mondal NB, Basu A., 2008. Therapeutic effect of a novel anilidoquinoline derivative, 2-(2-methyl-quinoline-4ylamino)-N-(2-chlorophenyl)-acetamide, in Japanese encephalitis: correlation with in vitro neuroprotection. Int. J. Antimicrob. Agents 32, 349-354.
    • (2008) Int. J. Antimicrob. Agents , vol.32 , pp. 349-354
    • Ghosh, J.1    Swarup, V.2    Saxena, A.3    Das, S.4    Hazra, A.5    Paira, P.6    Banerjee, S.7    Mondal, N.B.8    Basu, A.9
  • 26
    • 34548567422 scopus 로고    scopus 로고
    • A new, simple synthesis of 1,2-dihydroquinolines via cyclocondensation using zeolite catalyst
    • Hegedus A., Hell Z., Vargadi T., Potor A., Gresits I. A new, simple synthesis of 1,2-dihydroquinolines via cyclocondensation using zeolite catalyst. Catal. Lett. 2007, 117:99-101.
    • (2007) Catal. Lett. , vol.117 , pp. 99-101
    • Hegedus, A.1    Hell, Z.2    Vargadi, T.3    Potor, A.4    Gresits, I.5
  • 27
    • 55949127978 scopus 로고    scopus 로고
    • Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates
    • Horn J., Marsden S.P., Nelson A., House D., Weingarten G.G. Convergent, regiospecific synthesis of quinolines from o-aminophenylboronates. Org. Lett. 2008, 10:4117-4120.
    • (2008) Org. Lett. , vol.10 , pp. 4117-4120
    • Horn, J.1    Marsden, S.P.2    Nelson, A.3    House, D.4    Weingarten, G.G.5
  • 29
    • 77249159351 scopus 로고    scopus 로고
    • A method for the synthesis of substituted quinolines via electrophilic cyclization of 1-azido-2-(2-propynyl)benzene
    • Huo Z., Gridnev I.D., Yamamoto Y. A method for the synthesis of substituted quinolines via electrophilic cyclization of 1-azido-2-(2-propynyl)benzene. J. Org. Chem. 2010, 75:1266-1270.
    • (2010) J. Org. Chem. , vol.75 , pp. 1266-1270
    • Huo, Z.1    Gridnev, I.D.2    Yamamoto, Y.3
  • 30
    • 78650177754 scopus 로고    scopus 로고
    • Microwave-promoted alkynylation-cyclization of 2-aminoaryl ketones: a green strategy for the synthesis of 2,4-disubstituted quinolines
    • Iraj M.B., Shahram T., Majid M., Valiollah M., Salma A., Arsalan M. Microwave-promoted alkynylation-cyclization of 2-aminoaryl ketones: a green strategy for the synthesis of 2,4-disubstituted quinolines. Synlett 2010, 20:3104-3112.
    • (2010) Synlett , vol.20 , pp. 3104-3112
    • Iraj, M.B.1    Shahram, T.2    Majid, M.3    Valiollah, M.4    Salma, A.5    Arsalan, M.6
  • 31
    • 0027197490 scopus 로고
    • Treatment of chronic-relapsing experimental autoimmune encephalomyelitis with the synthetic immunomodulator linomide (quinoline-3-carboxamide)
    • Karussis D.M., Lehmann D., Slavin S., Karussis U.V., Koll R.M., Ovadia H., Kalland T., Abramsky O. Treatment of chronic-relapsing experimental autoimmune encephalomyelitis with the synthetic immunomodulator linomide (quinoline-3-carboxamide). Proc. Natl. Acad. Sci. USA 1993, 90:6400-6404.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6400-6404
    • Karussis, D.M.1    Lehmann, D.2    Slavin, S.3    Karussis, U.V.4    Koll, R.M.5    Ovadia, H.6    Kalland, T.7    Abramsky, O.8
  • 32
    • 67650725978 scopus 로고    scopus 로고
    • Design, synthesis, antifungal activity, and ADME prediction of functional analogues of terbinafine
    • Kharkar P.S., Deodhar M.N., Kulkarni V.M. Design, synthesis, antifungal activity, and ADME prediction of functional analogues of terbinafine. Med. Chem. Res. 2009, 18:421-432.
    • (2009) Med. Chem. Res. , vol.18 , pp. 421-432
    • Kharkar, P.S.1    Deodhar, M.N.2    Kulkarni, V.M.3
  • 33
    • 61349084177 scopus 로고    scopus 로고
    • Recent synthetic developments in a powerful imino Diels-Alder reaction (Povarov reaction): application to the synthesis of N-polyheterocycles and related alkaloids
    • Kouznetsov V.V. Recent synthetic developments in a powerful imino Diels-Alder reaction (Povarov reaction): application to the synthesis of N-polyheterocycles and related alkaloids. Tetrahedron 2009, 65:2721-2750.
    • (2009) Tetrahedron , vol.65 , pp. 2721-2750
    • Kouznetsov, V.V.1
  • 34
    • 57649155530 scopus 로고    scopus 로고
    • Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides
    • Kovi K.E., Yearick K., Iwaniuk D.P., Natarajan J.K., Alumasa J., de Dois A.C., Roepe P.D., Wolf C. Search for new pharmacophores for antimalarial activity. Part I: synthesis and antimalarial activity of new 2-methyl-6-ureido-4-quinolinamides. Bioorg. Med. Chem. 2009, 17:270-283.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 270-283
    • Kovi, K.E.1    Yearick, K.2    Iwaniuk, D.P.3    Natarajan, J.K.4    Alumasa, J.5    de Dois, A.C.6    Roepe, P.D.7    Wolf, C.8
  • 35
    • 77956432527 scopus 로고    scopus 로고
    • Ultrasound promoted synthesis of quinolines using basic ionic liquids in aqueous media as a green procedure
    • Kowsari E., Mallakmohammadi M. Ultrasound promoted synthesis of quinolines using basic ionic liquids in aqueous media as a green procedure. Ultrason. Sonochem. 2011, 18:447-454.
    • (2011) Ultrason. Sonochem. , vol.18 , pp. 447-454
    • Kowsari, E.1    Mallakmohammadi, M.2
  • 36
    • 56249130079 scopus 로고    scopus 로고
    • Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents
    • Kumar A., Srivastava K., Kumar S.R., Puri S.K., Chauhan P.M.S. Synthesis and bioevaluation of hybrid 4-aminoquinoline triazines as a new class of antimalarial agents. Bioorg. Med. Chem. Lett. 2008, 18:6530-6533.
    • (2008) Bioorg. Med. Chem. Lett. , vol.18 , pp. 6530-6533
    • Kumar, A.1    Srivastava, K.2    Kumar, S.R.3    Puri, S.K.4    Chauhan, P.M.S.5
  • 37
    • 80054716822 scopus 로고    scopus 로고
    • Design and synthesis of 2-chloroquinoline derivatives as non-azoles antimycotic agents
    • Kumar S., Bawa S., Drabu S., Panda B.P. Design and synthesis of 2-chloroquinoline derivatives as non-azoles antimycotic agents. Med. Chem. Res. 2011, 20:1340-1348.
    • (2011) Med. Chem. Res. , vol.20 , pp. 1340-1348
    • Kumar, S.1    Bawa, S.2    Drabu, S.3    Panda, B.P.4
  • 38
    • 41349094636 scopus 로고    scopus 로고
    • Indium(III) trifluoromethanesulfonate: an efficient reusable catalyst for the alkynylation-cyclization of 2-aminoaryl ketones and synthesis of 2,4-disubstituted quinolines
    • Lekhok K.C., Prajapati D., Boruah R.C. Indium(III) trifluoromethanesulfonate: an efficient reusable catalyst for the alkynylation-cyclization of 2-aminoaryl ketones and synthesis of 2,4-disubstituted quinolines. Synlett 2008, 5:655-658.
    • (2008) Synlett , vol.5 , pp. 655-658
    • Lekhok, K.C.1    Prajapati, D.2    Boruah, R.C.3
  • 39
    • 64549094601 scopus 로고    scopus 로고
    • Structure activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating mycobacterium tuberculosis
    • Lilienkampf A., Mao J., Wan B., Wang Y., Franzblau S.G., Kozikowski A.P. Structure activity relationships for a series of quinoline-based compounds active against replicating and nonreplicating mycobacterium tuberculosis. J. Med. Chem. 2009, 52:2109-2118.
    • (2009) J. Med. Chem. , vol.52 , pp. 2109-2118
    • Lilienkampf, A.1    Mao, J.2    Wan, B.3    Wang, Y.4    Franzblau, S.G.5    Kozikowski, A.P.6
  • 42
    • 58849125683 scopus 로고    scopus 로고
    • Synthesis, in vitro antitrypanosomal and antibacterial activity of phenoxy, phenylthio or benzyloxy substituted quinolones
    • Ma X., Zhou W., Brun R. Synthesis, in vitro antitrypanosomal and antibacterial activity of phenoxy, phenylthio or benzyloxy substituted quinolones. Bioorg. Med. Chem. Lett. 2009, 19:986-989.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 986-989
    • Ma, X.1    Zhou, W.2    Brun, R.3
  • 43
    • 34548555614 scopus 로고    scopus 로고
    • Synthesis of new 7-chloroquinolinyl thioureas and their biological investigation as potential anti-malarial and anticancer agents
    • Mahajan A., Yeh S., Nell M., Rensburg C.E.J., Chibale K. Synthesis of new 7-chloroquinolinyl thioureas and their biological investigation as potential anti-malarial and anticancer agents. Bioorg. Med. Chem. Lett. 2007, 17:5683-5685.
    • (2007) Bioorg. Med. Chem. Lett. , vol.17 , pp. 5683-5685
    • Mahajan, A.1    Yeh, S.2    Nell, M.3    Rensburg, C.E.J.4    Chibale, K.5
  • 46
    • 84861880315 scopus 로고    scopus 로고
    • An efficient one-pot cyclization of quinoline thiosemicarbazones to quinolines derivatized with 1,3,4-thiadiazole as anticancer and anti-tubercular agents
    • Marganakop S.B., Kamble R.R., Taj T., Kariduraganvar M.Y. An efficient one-pot cyclization of quinoline thiosemicarbazones to quinolines derivatized with 1,3,4-thiadiazole as anticancer and anti-tubercular agents. Med. Chem. Res. 2012, 21:185-191.
    • (2012) Med. Chem. Res. , vol.21 , pp. 185-191
    • Marganakop, S.B.1    Kamble, R.R.2    Taj, T.3    Kariduraganvar, M.Y.4
  • 47
    • 58049208387 scopus 로고    scopus 로고
    • Transition metal free indirect Friedlander synthesis of quinolines from alcohols
    • Martinez R., Ramon D.J., Yus M. Transition metal free indirect Friedlander synthesis of quinolines from alcohols. J. Org. Chem. 2008, 73:9778-9780.
    • (2008) J. Org. Chem. , vol.73 , pp. 9778-9780
    • Martinez, R.1    Ramon, D.J.2    Yus, M.3
  • 51
    • 58149483572 scopus 로고    scopus 로고
    • A domino three-component condensation of ortho-haloacetophenones with urea or amines: a novel one-pot synthesis of halogen-substituted quinolines
    • Qi C., Zheng Q., Hua R. A domino three-component condensation of ortho-haloacetophenones with urea or amines: a novel one-pot synthesis of halogen-substituted quinolines. Tetrahedron 2009, 65:1316-1320.
    • (2009) Tetrahedron , vol.65 , pp. 1316-1320
    • Qi, C.1    Zheng, Q.2    Hua, R.3
  • 53
    • 64549083684 scopus 로고    scopus 로고
    • Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform
    • Rano T.A., McMaster E.S., Pelton P.D., Yang M., Demarest K.T., Kuo G.H. Design and synthesis of potent inhibitors of cholesteryl ester transfer protein (CETP) exploiting a 1,2,3,4-tetrahydroquinoline platform. Bioorg. Med. Chem. Lett. 2009, 19:2456-2460.
    • (2009) Bioorg. Med. Chem. Lett. , vol.19 , pp. 2456-2460
    • Rano, T.A.1    McMaster, E.S.2    Pelton, P.D.3    Yang, M.4    Demarest, K.T.5    Kuo, G.H.6
  • 54
    • 0029957025 scopus 로고    scopus 로고
    • Novel bisquinoline antimalarials: synthesis, antimalarial activity and inhibition of haem polymerisation
    • Raynes K., Foley M., Tilley L., Deady L.W. Novel bisquinoline antimalarials: synthesis, antimalarial activity and inhibition of haem polymerisation. Biochem. Pharmacol. 1996, 52:551-559.
    • (1996) Biochem. Pharmacol. , vol.52 , pp. 551-559
    • Raynes, K.1    Foley, M.2    Tilley, L.3    Deady, L.W.4
  • 55
    • 25144488688 scopus 로고    scopus 로고
    • Synthesis and anthelmintic properties of arylquinolines with activity against drug-resistant nematodes
    • Rossiter S., Peron S.J., Whitfield P.J., Jones K. Synthesis and anthelmintic properties of arylquinolines with activity against drug-resistant nematodes. Bioorg. Med. Chem. Lett. 2005, 15:4806-4808.
    • (2005) Bioorg. Med. Chem. Lett. , vol.15 , pp. 4806-4808
    • Rossiter, S.1    Peron, S.J.2    Whitfield, P.J.3    Jones, K.4
  • 56
    • 0023939458 scopus 로고
    • Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids
    • Sanchez J.P., Domagala J.M., Hagen S.E., Heifetz C.L., Hutt M.P., Nichols J.B., Trehan A.K. Quinolone antibacterial agents. Synthesis and structure-activity relationships of 8-substituted quinoline-3-carboxylic acids and 1,8-naphthyridine-3-carboxylic acids. J. Med. Chem. 1988, 31:983-991.
    • (1988) J. Med. Chem. , vol.31 , pp. 983-991
    • Sanchez, J.P.1    Domagala, J.M.2    Hagen, S.E.3    Heifetz, C.L.4    Hutt, M.P.5    Nichols, J.B.6    Trehan, A.K.7
  • 57
    • 57649115450 scopus 로고    scopus 로고
    • Ionic liquid - an efficient recyclable system for the synthesis of 2,4-disubstituted quinolines via Meyer-Schuster rearrangement
    • Sarma R., Prajapati D. Ionic liquid - an efficient recyclable system for the synthesis of 2,4-disubstituted quinolines via Meyer-Schuster rearrangement. Synlett 2008, 19:3001-3005.
    • (2008) Synlett , vol.19 , pp. 3001-3005
    • Sarma, R.1    Prajapati, D.2
  • 59
    • 58549097259 scopus 로고    scopus 로고
    • Substituted 1,2,3,4-tetrahydroquinolin-6-yloxypropanes as β3-adrenergic receptor agonists: design, synthesis, biological evaluation and pharmacophore modeling
    • Shakya N., Roy K.K., Saxena A.K. Substituted 1,2,3,4-tetrahydroquinolin-6-yloxypropanes as β3-adrenergic receptor agonists: design, synthesis, biological evaluation and pharmacophore modeling. Bioorg. Med. Chem. 2009, 17:830-847.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 830-847
    • Shakya, N.1    Roy, K.K.2    Saxena, A.K.3
  • 61
    • 84856226189 scopus 로고    scopus 로고
    • Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives
    • Singh B., Chetia D., Puri S.K., Srivastava K., Prakash A. Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives. Med. Chem. Res. 2011, 20:1523-1529.
    • (2011) Med. Chem. Res. , vol.20 , pp. 1523-1529
    • Singh, B.1    Chetia, D.2    Puri, S.K.3    Srivastava, K.4    Prakash, A.5
  • 64
    • 0025077299 scopus 로고
    • Pharmacological studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (centhaquin). I. Hypotensive activity
    • Srimal R.C., Gulati K., Nityanand S., Dhawan B.N. Pharmacological studies on 2-(2-(4-(3-methylphenyl)-1-piperazinyl)ethyl) quinoline (centhaquin). I. Hypotensive activity. Pharmacol. Res. 1990, 22:319-329.
    • (1990) Pharmacol. Res. , vol.22 , pp. 319-329
    • Srimal, R.C.1    Gulati, K.2    Nityanand, S.3    Dhawan, B.N.4
  • 65
    • 62949103794 scopus 로고    scopus 로고
    • Design, synthesis, biological evaluation and molecular modelling studies of novel quinoline derivatives against Mycobacterium tuberculosis
    • Upadhayaya R.S., Vandavasi J.K., Vasireddy N.R., Sharma V., Dixit S.S., Chattopadhyaya J. Design, synthesis, biological evaluation and molecular modelling studies of novel quinoline derivatives against Mycobacterium tuberculosis. Bioorg. Med. Chem. 2009, 17:2830-2841.
    • (2009) Bioorg. Med. Chem. , vol.17 , pp. 2830-2841
    • Upadhayaya, R.S.1    Vandavasi, J.K.2    Vasireddy, N.R.3    Sharma, V.4    Dixit, S.S.5    Chattopadhyaya, J.6
  • 67
  • 68
    • 62649173577 scopus 로고    scopus 로고
    • One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: ytterbium perfluorooctanoate catalysed Doebner reaction
    • Wang L.M., Hu L., Chen H.J., Sui Y.Y., Shen W. One-pot synthesis of quinoline-4-carboxylic acid derivatives in water: ytterbium perfluorooctanoate catalysed Doebner reaction. J. Fluorine Chem. 2009, 130:406-409.
    • (2009) J. Fluorine Chem. , vol.130 , pp. 406-409
    • Wang, L.M.1    Hu, L.2    Chen, H.J.3    Sui, Y.Y.4    Shen, W.5
  • 69
    • 62749156417 scopus 로고    scopus 로고
    • Sulfuric acid promoted condensation cyclization of 2-(2-(trimethylsilyl) ethynyl)anilines with arylaldehydes in alcoholic solvents: an efficient one-pot synthesis of 4-alkoxy-2-arylquinolines
    • Wang Y., Peng C., Liu L., Zhao J., Su L., Zhu Q. Sulfuric acid promoted condensation cyclization of 2-(2-(trimethylsilyl) ethynyl)anilines with arylaldehydes in alcoholic solvents: an efficient one-pot synthesis of 4-alkoxy-2-arylquinolines. Tetrahedron Lett. 2009, 50:2261-2265.
    • (2009) Tetrahedron Lett. , vol.50 , pp. 2261-2265
    • Wang, Y.1    Peng, C.2    Liu, L.3    Zhao, J.4    Su, L.5    Zhu, Q.6
  • 70
    • 79953772942 scopus 로고    scopus 로고
    • Synthesis and c-Met kinase inhibition of 3,5-disubstituted and 3,5,7-trisubstituted quinolines: identification of 3-(4 acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7 (trifluoromethyl)quinoline as a novel anticancer agent
    • Wang Y., Ai J., Wang Y., Chen Y., Wang L., Liu G., Geng M., Zhang A. Synthesis and c-Met kinase inhibition of 3,5-disubstituted and 3,5,7-trisubstituted quinolines: identification of 3-(4 acetylpiperazin-1-yl)-5-(3-nitrobenzylamino)-7 (trifluoromethyl)quinoline as a novel anticancer agent. J. Med. Chem. 2011, 54:2127-2142.
    • (2011) J. Med. Chem. , vol.54 , pp. 2127-2142
    • Wang, Y.1    Ai, J.2    Wang, Y.3    Chen, Y.4    Wang, L.5    Liu, G.6    Geng, M.7    Zhang, A.8
  • 71
  • 72
    • 78049518506 scopus 로고    scopus 로고
    • Synthesis of 2-alkoxy(aroxy)-3-substituted quinolines by DABCO promoted cyclization of o-alkynylaryl isocyanides
    • Zhao J., Peng C., Liu L., Wang Y., Zhu Q. Synthesis of 2-alkoxy(aroxy)-3-substituted quinolines by DABCO promoted cyclization of o-alkynylaryl isocyanides. J. Org. Chem. 2010, 75:7502-7504.
    • (2010) J. Org. Chem. , vol.75 , pp. 7502-7504
    • Zhao, J.1    Peng, C.2    Liu, L.3    Wang, Y.4    Zhu, Q.5
  • 73
    • 38949118023 scopus 로고    scopus 로고
    • A convenient synthesis of quinolines via ionic liquid-catalysed friedlander annulation
    • Zhou T., Lin J., Chen Z. A convenient synthesis of quinolines via ionic liquid-catalysed friedlander annulation. Lett. Org. Chem. 2008, 5:47-50.
    • (2008) Lett. Org. Chem. , vol.5 , pp. 47-50
    • Zhou, T.1    Lin, J.2    Chen, Z.3
  • 74
    • 59249099229 scopus 로고    scopus 로고
    • The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones
    • Zhou W., Zhang L., Jiao N. The tandem reaction combining radical and ionic processes: an efficient approach to substituted 3,4-dihydroquinolin-2-ones. Tetrahedron 2009, 65:1982-1987.
    • (2009) Tetrahedron , vol.65 , pp. 1982-1987
    • Zhou, W.1    Zhang, L.2    Jiao, N.3
  • 75
    • 0000663750 scopus 로고    scopus 로고
    • One step synthesis for the preparation of quinoline alkaloid analogues
    • Zografos A.L., Mitsos C.A., Markopoulou O.I. One step synthesis for the preparation of quinoline alkaloid analogues. Org. Lett. 1999, 1:1953-1955.
    • (1999) Org. Lett. , vol.1 , pp. 1953-1955
    • Zografos, A.L.1    Mitsos, C.A.2    Markopoulou, O.I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.