Synthesis and in vitro and in vivo antimalarial activity of novel 4-anilinoquinoline Mannich base derivatives

Medicinal Chemistry Research

Volumn 20, Issue 9, 2011, Pages 1523-1529

  Singh, Bhupendra ^a,d   Chetia, Dipak ^a   Puri, S K ^b   Srivastava, Kumkum ^b   Prakash, Anil ^c  

^a DIBRUGARH UNIVERSITY   (India)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

^c REGIONAL MEDICAL RESEARCH CENTRE   (India)

^d S N MEDICAL COLLEGE   (India)

Author keywords

4 Anilinoquinoline; Antimalarial; In vitro; In vivo; Mannich base; P. falciparum

Indexed keywords

2 BUTYLAMINOMETHYL 4 (7 CHLORO QUINOLIN 4 YLAMINO)PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 (ISOPROPYLAMINOMETHYL)PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 [(DIISOPROPYLAMINO)METHYL]PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 [(DIPHENYLAMINO)METHYL]PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 DIBUTYLAMINOMETHYL PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 MORPHOLIN 4 YLMETHYL PHENOL; 4 (7 CHLORO QUINOLIN 4 YLAMINO) 2 N PROPYLAMINOMETHYLPHENOL; 4 ANILINOQUINOLINE MANNICH BASE DERIVATIVE; ANTIMALARIAL AGENT; CHLOROQUINE; MANNICH BASE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CONFERENCE PAPER; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN TISSUE; INFRARED SPECTROMETRY; MANNICH REACTION; MASS SPECTROMETRY; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; PLASMODIUM YOELII INFECTION; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84856226189     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-010-9397-z     Document Type: Conference Paper

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