Synthesis of new 7-chloroquinolinyl thioureas and their biological investigation as potential antimalarial and anticancer agents

Bioorganic and Medicinal Chemistry Letters

Volumn 17, Issue 20, 2007, Pages 5683-5685

  Mahajan, Aman ^a   Yeh, Susan ^b   Nell, Margo ^c   van Rensburg, Constance E J ^c   Chibale, Kelly ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

4 Quinolyl isothiocyanate; 7 Chloroquinolinyl thioureas; Human adenocarcinoma of the cervix; Plasmodium falciparum

Indexed keywords

7 CHLOROQUINOLINYL THIOUREA; QUINOLINE DERIVATIVE; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DETERMINATION; DRUG INHIBITION; DRUG SELECTIVITY; DRUG SYNTHESIS; HELA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; PLASMODIUM FALCIPARUM;

ANIMALS; ANTIMALARIALS; ANTIPARASITIC AGENTS; CHLOROQUINE; HELA CELLS; HUMANS; MOLECULAR STRUCTURE; PLASMODIUM FALCIPARUM; STRUCTURE-ACTIVITY RELATIONSHIP; THIOUREA;

PLASMODIUM FALCIPARUM;

EID: 34548555614     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.07.049     Document Type: Article

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