Synthesis and in vitro antitubercular activity of a series of quinoline derivatives

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 4, 2009, Pages 1474-1480

  de Souza, Marcus V N ^a   Pais, Karla C ^a,b   Kaiser, Carlos R ^b   Peralta, Mônica A ^a   de L Ferreira, Marcelle ^a,b   Lourenço, Maria C S ^c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c Funda??o Oswaldo Cruz   (Brazil)

Author keywords

Antitubercular activity; Drugs; MDR TB; Quinoline

Indexed keywords

2 [(7 CHLOROQQUINOLIN 4 YL)AMINO]BUTAN 1 OL; 2 [(7 CHLOROQUINOLIN 4 YL)AMINO]ETHANOL; 2 [[2 [(7 CHLOROQUINOLIN 4 YL)AMINO]ETHYL]AMINO]ETHANOL; 3 [(7 CHLOROQUINOLIN 4 YL)AMINO]PROPAN 1 OL; 3 [(7 CHLOROQUINOLIN 4 YL)AMINO]PROPANENITRILE; 4 AMINO 7 CHLOROQUINOLINE; 4 AZIDO 7 CHLOROQUINOLINE; 7 CHLORO 4 DIAMINOQUINOLINE DERIVATIVE; 7 CHLORO N (2 CHLOROETHYL)QUINOLIN 4 AMINE; 7 CHLORO N BUTYL QUINOLIN 4 AMINE; 7 CHLORO N ISOPROPYLQUINOLIN 4 AMINE; 7 CHLORO N METHYLQUINOLIN 4 AMINE; 7 CHLORO N PROPYLQUINOLIN 4 AMINE; ETHAMBUTOL; N (2 AZIDOETHYL) 7 CHLOROQUINOLIN 4 AMINE; N (7 CHLOROQUINOLIN 4 Y)HEXANE 1,6 DIAMINE; N (7 CHLOROQUINOLIN 4 YL) N' CYCLOHEXYLETHANE 1,2 DIAMINE; N (7 CHLOROQUINOLIN 4 YL) N' ISOPROPYLETHANE 1,2 DIAMINE; N (7 CHLOROQUINOLIN 4 YL) N' METHYLETHANE 1,2 DIAMINE; N (7 CHLOROQUINOLIN 4 YL) N' PROPYLETHANE 1,2 DIAMINE; N (7 CHLOROQUINOLIN 4 YL)BUTANE 1,4 DIAMINE; N (7 CHLOROQUINOLIN 4 YL)DECANE 1,10 DIAMINE; N (7 CHLOROQUINOLIN 4 YL)ETHANE 1,2 DIAMINE; N (7 CHLOROQUINOLIN 4 YL)OCTANE 1,8 DIAMINE; N (7 CHLOROQUINOLIN 4 YL)PROPANE 1,3 DIAMINE; N BENZYL N' (7 CHLOROQUINOLIN 4 YL)ETHANE 1,2 DIAMINE; N BUTYL N' (7 CHLOROQUINOLIN 4 YL)ETHANE 1,2 DIAMINE; QUINOLINE DERIVATIVE; TUBERCULOSTATIC AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG SYNTHESIS; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS;

ANTITUBERCULAR AGENTS; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBERCULOSIS, MULTIDRUG-RESISTANT;

MYCOBACTERIUM TUBERCULOSIS;

EID: 60049090432     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.01.013     Document Type: Article

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