Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining

DNA Repair

Volumn 12, Issue 1, 2013, Pages 38-45

  Bergs, Judith W J ^a   Krawczyk, Przemek M ^a   Borovski, Tijana ^a   ten Cate, Rosemarie ^a   Rodermond, Hans M ^a   Stap, Jan ^a   Medema, Jan Paul ^a   Haveman, Jaap ^a   Essers, Jeroen ^b   van Bree, Chris ^a   Stalpers, Lukas J A ^a   Kanaar, Roland ^b   Aten, Jacob A ^a   Franken, Nicolaas A P ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

Chromosomal translocations; GammaH2AX foci; Hyperthermia; Inhibition of homologous recombination; NU7441; RAD51 foci

Indexed keywords

CISPLATIN; PROTEIN KINASE INHIBITOR; RAD51 PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CHROMOSOME ABERRATION; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CONTROLLED STUDY; DNA END JOINING REPAIR; DOUBLE STRANDED DNA BREAK; EMBRYO; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HYPERTHERMIC THERAPY; IONIZING RADIATION; MOUSE; NONHUMAN; PREMATURE CHROMOSOME CONDENSATION; PRIORITY JOURNAL; RECOMBINATION REPAIR;

ANIMALS; CELL LINE, TUMOR; CHROMONES; CISPLATIN; DNA BREAKS, DOUBLE-STRANDED; DNA END-JOINING REPAIR; G2 PHASE; GAMMA RAYS; HOMOLOGOUS RECOMBINATION; HOT TEMPERATURE; HUMANS; MICE; MORPHOLINES; RADIATION TOLERANCE; RECOMBINATIONAL DNA REPAIR; TRANSLOCATION, GENETIC;

MAMMALIA;

EID: 84871715285     PISSN: 15687864     EISSN: 15687856     Source Type: Journal    
DOI: 10.1016/j.dnarep.2012.10.008     Document Type: Article

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