Importance of TP53 and RB in the repair of potentially lethal damage and induction of color junctions after exposure to ionizing radiation

Radiation Research

Volumn 158, Issue 6, 2002, Pages 707-714

  Franken, N A P ^a   Van Bree, C ^a   Ten Cate, R ^a   Van Oven, C H ^a   Haveman, J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL CYCLE G1 PHASE; CELL DAMAGE; CELL REGENERATION; CELL SURVIVAL; CHROMOSOME 18; CHROMOSOME 19; CONTROLLED STUDY; HUMAN; HUMAN CELL; IONIZING RADIATION; MITOSIS INHIBITION; PRIORITY JOURNAL; PROTEIN FUNCTION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION INJURY;

EID: 0036894094     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/0033-7587(2002)158[0707:IOTARI]2.0.CO;2     Document Type: Article

References (34)

1. M. B. Kastan, O. Onyekwere, D. Sidransky, B. Vogelstein and R. W. Craig, Participation of p53 protein in the cellular response to DNA damage. Cancer Res. 51, 6304-6311 (1991).
2. S. J. Kuerbitz, B. S. Plunkett, W. V. Walsh and M. B. Kastan, Wildtype p53 is a cell cycle checkpoint determinant following irradiation. Proc. Natl. Acad. Sci. USA 89, 7491-7495 (1992).
3. T. D. Kessis, R. J. Slebos, W. G. Nelson, M. B. Kastan, B. S. Plunkett, S. M. Han, A. T Lorincz, L. Hedrick and K. R. Cho, Human papillomavirus 16 E6 expression disrupts the p53-mediated cellular response to DNA damage. Proc. Natl. Acad. Sci. USA 90, 3988-3992 (1993).
4. T. L. DeWeese, J. C. Walsh, L. E. Dillehay, T. D. Kessis, L. Hedrick, K. R. Cho and W. G. Nelson, Human papillomavirus E6 and E7 oncoproteins alter cell cycle progression but not radiosensitivity of carcinoma cells treated with low-dose-rate radiation. Int. J. Radiat. Oncol. Biol. Phys. 37, 145-154 (1997).
5. 1 arrest involves pRb-related proteins and is disrupted by the human papillomavirus 16 E7 oncoprotein. Proc. Natl. Acad. Sci. USA 91, 5320-5324 (1994).
6. A. Chen and J. L. Schwartz, Inhibition and recovery of DNA synthesis in human tumor cell lines following radiation exposure. Radiat. Res. 118, 375-380 (1989).
7. J. C. Ribeiro, A. R. Barnetson, R. J. Fisher, H. Mameghan and P. J. Russell, Relationship between radiation response and p53 status in human bladder cancer cells. Int. J. Radiat. Biol. 72, 11-20 (1997).
8. 1 checkpoint does not decrease cell survival following DNA damage. Cancer Res. 53, 4164-4168 (1993).
9. 1 arrest or protein levels of p53, myc, ras or raf in human melanoma lines. Int. J. Radiat. Biol. 75, 1149-1160 (1999).
10. N. M. Tsang, H. Nagasawa, C. Li and J. B. Little, Abrogation of p53 function by transfection of HPV16 E6 gene enhances the resistance of human diploid fibroblasts to ionizing radiation. Oncogene 10, 2403-2408 (1995).
11. G. L. Yount, D. A. Haas-Kogan, C. A. Vidair, M. Haas, W. C. Dewey and M. A. Israel, Cell cycle synchrony unmasks the influence of p53 function on radiosensitivity of human glioblastoma cells. Cancer Res. 56, 500-506 (1996).
12. C. E. Ng, S. K. Banerjee, M. Pavliv, G. Wang, G. P. Raaphorst and R. A. Aubin, p53 status, cellular recovery and cell cycle arrest as prognosticators of in vitro radiosensitivity in human pancreatic adenocarcinoma cell lines. Int. J. Radiat. Biol. 75, 1365-1376 (1999).
13. D. A. Haas-Kogan, S. S. Kogan, G. Yount, J. Hsu, M. Haas, D. F. Deen and M. A. Israel, p53 function influences the effect of fractionated radiotherapy on glioblastoma tumors. Int. J. Radiat. Oncol. Biol. Phys. 43, 399-403 (1999).
14. J. L. Schwartz, J. Rasey, L. Wiens, R. Jordan and K. J. Russell, Functional inactivation of p53 by HPV-E6 transformation is associated with a reduced expression of radiation-induced potentially lethal damage. Int. J. Radiat. Biol. 75, 285-291 (1999).
15. J. L. Schwartz, R. Jordan, W. K. Kaufmann, J. Rasey, K. J. Russell and R. R. Weichselbaum, Evidence for the expression of radiation-induced potentially lethal damage being a p53-dependent process. Int. J. Radiat. Biol. 76, 1037-1043 (2000).
16. K. L. Mekeel, W. Tang, L. A. Kachnic, C. M. Luo, J. S. DeFrank and S. N. Powell, Inactivation of p53 results in high rates of homologous recombination. Oncogene 14, 1847-1857 (1997).
17. W. Tang, H. Willers and S. N. Powell, p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in γ-irradiated mouse fibroblasts. Cancer Res. 59, 2562-2565 (1999).
18. H. Willers, E. E. McCarthy, W. Alberti, J. Dahm-Daphi and S. N. Powell, Loss of wild-type p53 function is responsible for upregulated homologous recombination in immortal rodent fibroblasts. Int. J. Radiat. Biol. 76, 1055-1062 (2000).
19. J. L. Schwartz and K. J. Russell, The effect of functional inactivation of TP53 by HPV-E6 transformation on the induction of chromosome aberrations by gamma rays in human tumor cells. Radiat. Res. 151, 385-390 (1999).
20. 1-phase checkpoint. Radiat. Res. 145, 289-298 (1996).
21. H. Caron, B. van Schaik, M. van der Mee, F. Baas, G. Riggins, P. van Sluis, M-C. Hermus, R. van Asperen, K. Boon, P. A. Voute and R. Versteeg, The human transcriptome map: Clustering of highly expressed genes in chromosomal domains. Science 291, 1289-1293 (2001).
22. C. van Bree, B. van Der Maat, H. M. Ceha, N. A. P. Franken, J. Haveman and P. J. Bakker, Inactivation of p53 and of pRb protects human colorectal carcinoma cells against hyperthermia-induced cytotoxicity and apoptosis. J. Cancer Res. Clin. Oncol. 125, 549-555 (1999).
23. C. van Bree, J. H. Savonije, N. A. P. Franken, J. Haveman and P. J. Bakker, The effect of p53-function on the sensitivity to paclitaxel with or without hyperthermia in human colorectal carcinoma cells. Int. J. Oncol. 16, 739-744 (2000).
24. G. W. Barendsen, Parameters of linear-quadratic radiation dose-effect relationships: Dependence on LET and mechanisms of reproductive cell death. Int. J. Radiat. Biol. 71, 649-655 (1997).
25. A. T. Natarajan, R. C. Vyas, F. Darroudi and S. Vermeulen, Frequencies of x-ray-induced chromosome translocations in human peripheral lymphocytes as detected by in situ hybridization using chromosome-specific DNA libraries. Int. J. Radiat. Biol. 61, 199-203 (1992).
26. J. D. Tucker, W. F. Morgan, A. A. Awa, M. Bauchinger, D. Blakey, M. N. Cornforth, L. G. Littlefield, A. T. Natarajan and C. Shasserre, A proposed system for structural aberrations detected by chromosome painting. Cytogenet. Cell Genet. 68, 211-221 (1995).
27. N. A. P. Franken, C. van Bree, M. A. Veltmaat, H. M. Rodermond, J. Haveman and G. W. Barendsen, Radiosensitization by bromodeoxyuridine and hyperthermia: Analysis of linear and quadratic parameters of radiation survival curves of two human tumor cell lines. J. Radiat. Res. 42, 179-190 (2001).
28. S. P. Linke, K. C. Clarkin and G. M. Wahl, P53 mediates permanent arrest over multiple cell cycles in response to γ-irradiation. Cancer Res. 57, 1171-1179 (1997).
29. P. S. Surralles, M. J. Ramirez, A. Creus and R. Marcos, Equal and persistence of chromosome aberrations involving chromosomes with heterogenous lengths and gene densities. Cytogenet. Cell Genet. 87, 62-68 (1999).
30. J. Coco-Martin, E. Mooren, C. Ottenheim, W. Burrill, M. I. Nunez, D. Sprong, H. Bartelink and A. C. Begg, Potential of radiation-induced chromosome aberrations to predict radiosensitivity in human tumour cells. Int. J. Radiat. Biol. 75, 1161-1168 (1999).
31. N. A. P. Franken, P. Ruurs, G. Ludwikow, C. van Bree, J. B. Kipp, F. Darroudi and G. W. Barendsen, Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and high doses of radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells. Int. J. Radiat. Biol. 75, 293-299 (1999).
32. N. Castro Kreder, C. van Bree, N. A. P. Franken and J. Haveman, Predictive value of FISH: Correlation between cell survival and chromosomal aberrations after high dose rate and pulsed low dose rate irradiation. Int. J. Radiat Biol. 78, 203-210 (2002).
33. F. Darroudi, J. Fomina, M. Meijers and A. T. Natarajan, Kinetics of the formation of chromosome aberrations in X-irradiated human lymphocytes, using PCC and FISH. Mutat. Res. 404, 55-65 (1998).
34. R. Greinert, B. Volkmer, R. P. Virsik-Peuckert and D. Harder, Comparative study of the repair kinetics of chromosomal aberrations and DNA strand breaks in proliferating and quiescent CHO cells. Int. J. Radiat. Biol. 70, 33-43 (1996).