The Rad51 paralog Rad51B promotes homologous recombinational repair

Molecular and Cellular Biology

Volumn 20, Issue 17, 2000, Pages 6476-6482

  Takata, M ^a   Sasaki, M S ^a   Sonoda, E ^a   Fukushima, T ^a   Morrison, C ^a   Albala, J S ^a   Swagemakers, S M A ^a   Kanaar, R ^a   Thompson, L H ^a   Takeda, S ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; IMMUNOGLOBULIN; MITOMYCIN C; MUTANT PROTEIN; NUCLEOPROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CROSS LINKING; DNA RECOMBINATION; DNA REPAIR; GENE TARGETING; MEIOSIS; MITOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SACCHAROMYCES CEREVISIAE;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL DIVISION; CELL LINE; CELL SEPARATION; CHICKENS; CHROMOSOME ABERRATIONS; CISPLATIN; DNA REPAIR; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; FLOW CYTOMETRY; FUNGAL PROTEINS; GAMMA RAYS; GENE LIBRARY; GENE TARGETING; MITOMYCIN; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NUCLEIC ACID SYNTHESIS INHIBITORS; PHENOTYPE; RADIATION-SENSITIZING AGENTS; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; SISTER CHROMATID EXCHANGE;

ANIMALIA; GALLUS GALLUS; SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 0033846527     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.17.6476-6482.2000     Document Type: Article

References (67)

1. Semidominant suppressors of Srs2 helicase mutations of Saccharomyces cerevisiae map in the RAD51 gene, whose sequence predicts a protein with similarities to procaryotic RecA proteins
2. Identification of a novel human RAD51 homolog, RAD51B
3. Nucleotide sequence and transcriptional regulation of the yeast recombinational repair gene RAD51
4. Role of the human RAD51 protein in homologous recombination and double-stranded-break repair
5. Reduced X-ray resistance and homologous recombination frequencies in a RAD54-/- mutant of the chicken DT40 cell line
6. Xrcc3 is required for assembly of Rad51 complexes in vivo
7. DMC1: A meiosis-specific yeast homolog of E. coli recA required for recombination, synaptonemal complex formation, and cell cycle progression
8. Identification of a Saccharomyces cerevisiae Ku80 homologue: Roles in DNA double strand break rejoining and in telomeric maintenance
9. Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways
10. Evolutionary comparisons of RecA-like proteins across all major kingdoms of living organisms
11. Light chain gene conversion continues at high rate in an ALV-induced cell line
12. Increased ratio of targeted to random integration after transfection of chicken B cell lines
13. Cross-sensitivity of γ-ray-sensitive hamster mutants to cross-linking agents
14. Isolation of novel human and mouse genes of the recA/RAD51 recombination-repair gene family
15. The XRCC2 DNA repair gene from human and mouse encodes a novel member of the recA/RAD51 family
16. Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
17. A broadening view of recombinational DNA repair in bacteria
18. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes
19. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination
20. Rad52 associates with RPA and functions with rad55 and rad57 to assemble meiotic recombination complexes
21. Nuclear foci of mammalian Rad51 recombination protein in somatic cells after DNA damage and its localization in synaptonemal complexes
22. DNA recombination: The replication connection
23. The mouse and human homologs of DMC1, the yeast meiosis-specific homologous recombination gene, have a common unique form of exon-skipped transcript in meiosis
24. Integrating genetic approaches into the discovery of anticancer drugs
25. Complex formation in yeast double-strand break repair: Participation of Rad51, Rad52, Rad55, and Rad57 proteins
26. Mutations of a novel human RAD54 homologue, RAD54B, in primary cancer
27. Functional differences and interactions among the putative RecA homologs Rad51, Rad55, and Rad57
28. Mammalian XRCC2 promotes the repair of DNA double-strand breaks by homologous recombination
29. Molecular mechanisms of DNA double strand break repair
30. Sequence analysis and expression of a novel mouse homolog of Escherichia coli recA gene
31. Stable DNA replication: Interplay between DNA replication, homologous recombination, and transcription
32. In vitro reconstitution of homologous recombination reactions
33. Nuclear Rad51 foci induced by DNA damage are distinct from Rad51 foci associated with B cell activation and recombination
34. Homology-directed repair is a major double-strand break repair pathway in mammalian cells
35. Multiple pathways for repair of DNA double-strand breaks in mammalian chromosomes
36. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA crosslinks and other damages
37. Sequence of the RAD55 gene of Saccharomyces cerevisiae: Similarity of RAD55 to prokaryotic RecA and other RecA-like proteins
38. hMre11 and hRad50 nuclear foci are induced during the normal cellular response to DNA double-strand breaks
39. Mutations in the RAD54 recombination gene in primary cancers
40. Chromosome instability syndromes: Lessons for carcinogenesis
41. RecA-like recombination proteins in eukaryotes: Functions and structures of RAD51 genes
42. Analysis of the human Rad51L1 promoter region and its activation by UV light
43. Catalysis of homologous DNA pairing by yeast Rad51 and Rad54 proteins
44. XRCC3 promotes homology-directed repair of DNA damage in mammalian cells
45. Identification, characterization, and genetic mapping of Rad51d, a new mouse and human Rad51/RecA-related gene
46. Nuclear foci of mammalian recombination proteins are located at single-stranded DNA regions formed after DNA damage
47. Isolation of human and mouse genes based on homology to REC2, a recombinational repair gene from the fungus Ustilago maydis
48. Allelic knockout of novel splice variants of human recombination repair gene RAD51B in t(12;14) uterine leiomyomas
49. Cloning of human, mouse and fission yeast recombination genes homologous to RAD51 and recA
50. Rad51 protein involved in repair and recombination in S. cerevisiae is a RecA-like protein
51. Homologous recombination and the roles of double-strand breaks
52. Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can be partially rescued in a p53(-/-) background
53. The Saccharomyces cerevisiae Ku autoantigen homologue affects radiosensitivity only in the absence of homologous recombination
54. Rad51 deficient vertebrate cells accumulate chromosomal breaks prior to cell death
55. Sister chromatid exchanges are mediated by homologous recombination in vertebrate cells
56. Genetic evidence for involvement of type 1, type 2 and type 3 inositol 1,4,5-trisphosphate receptors in signal transduction through the B-cell antigen receptor
57. Yeast Rad55 and Rad57 proteins form a heterodimer that functions with replication protein A to promote DNA strand exchange by Rad51 recombinase
58. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
59. RAG-2 expression is not essential for chicken immunoglobulin gene conversion
60. Mouse Rad54 affects DNA conformation and DNA-damage-induced Rad51 loci formation
61. S phase specific formation of the human Rad51 protein nuclear foci in lymphocytes
62. Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene
63. A surfeit of RAD51-like genes?
64. The contribution of homologous recombination in preserving genome integrity in mammalian cells
65. Homologous recombination, but not DNA repair, is reduced in vertebrate cells deficient in RAD52
66. BRCA2 is required for ionizing radiation-induced assembly of Rad51 complex in vivo
67. Cisplatin and DNA repair in cancer chemotherapy