Prasugrel metabolites inhibit neutrophil functions

Journal of Pharmacology and Experimental Therapeutics

Volumn 344, Issue 1, 2013, Pages 231-243

  Liverani, Elisabetta ^a   Rico, Mario C ^a   Garcia, Analia E ^a   Kilpatrick, Laurie E ^a,b   Kunapuli, Satya P ^a,b  

^a TEMPLE UNIVERSITY HOSPITAL   (United States)

^b TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CANGRELOR; CD11B ANTIGEN; CD16 ANTIGEN; DRUG METABOLITE; FIBRINOGEN RECEPTOR; FORMYLMETHIONYLLEUCYLPHENYLALANINE; MITOGEN ACTIVATED PROTEIN KINASE; MYELOPEROXIDASE; PRASUGREL; PURINERGIC P2Y12 RECEPTOR; PURINERGIC P2Y13 RECEPTOR; THROMBOCYTE ACTIVATING FACTOR;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM MOBILIZATION; CELL INTERACTION; CELL VIABILITY; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKOCYTE ACTIVATION; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THROMBOCYTE AGGREGATION INHIBITION;

ANIMALS; ANTIGENS, CD11B; BLOTTING, WESTERN; CALCIUM; CELL SEPARATION; CELL SURVIVAL; CHEMOTAXIS, LEUKOCYTE; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; NEUTROPHILS; PEROXIDASE; PIPERAZINES; PLATELET AGGREGATION; PURINERGIC P2 RECEPTOR ANTAGONISTS; PURINERGIC P2Y RECEPTOR ANTAGONISTS; RECEPTORS, PURINERGIC P2Y12; THIOPHENES;

EID: 84871698742     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.195883     Document Type: Article

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