Protective effects of coffee diterpenes against aflatoxin B1-induced genotoxicity: Mechanisms in rat and human cells

Food and Chemical Toxicology

Volumn 39, Issue 6, 2001, Pages 549-556

  Cavin, C ^a   Mace, K ^a   Offord, E A ^a   Schilter, B ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

Aflatoxin B1; Cafestol and kahweol; Chemoprotection; Coffee

Indexed keywords

AFLATOXIN B1; CAFESTOL; CYTOCHROME P450 2C11; CYTOCHROME P450 3A; CYTOCHROME P450 3A2; DNA; GLUTATHIONE TRANSFERASE; KAHWEOL; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ANIMAL CELL; ARTICLE; CHEMOPROPHYLAXIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETOXIFICATION; DNA ADDUCT; DNA BINDING; DRUG EFFECT; DRUG MECHANISM; ENZYME SUBUNIT; EPITHELIUM CELL; GENOTOXICITY; HUMAN; HUMAN CELL; LIVER CELL; LIVER MICROSOME; NONHUMAN; PROTEIN EXPRESSION; RAT;

AFLATOXIN B1; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHEMOPREVENTION; COFFEE; CYTOCHROME P-450 ENZYME SYSTEM; DITERPENES; DNA ADDUCTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEPATOCYTES; HUMANS; LIVER; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0035003959     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(00)00168-X     Document Type: Article

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