Leukotriene E4-induced pulmonary inflammation is mediated by the P2Y12 receptor

Journal of Experimental Medicine

Volumn 206, Issue 11, 2009, Pages 2543-2555

  Paruchuri, Sailaja ^a,b   Tashimo, Hiroyuki ^a,b   Feng, Chunli ^b   Maekawa, Akiko ^a,b   Xing, Wei ^a,b   Jiang, Yongfeng ^a,b   Kanaoka, Yoshihide ^a,b   Conley, Pamela ^c   Boyce, Joshua A ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c Portola Pharmaceuticals Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CHEMOKINE; CYSTEINYL LEUKOTRIENE 1 RECEPTOR; CYSTEINYL LEUKOTRIENE 2 RECEPTOR; G PROTEIN COUPLED RECEPTOR; INTERLEUKIN 13; LEUKOTRIENE D4; LEUKOTRIENE E4; MITOGEN ACTIVATED PROTEIN KINASE; PROSTAGLANDIN D2; PURINERGIC P2Y12 RECEPTOR; UNCLASSIFIED DRUG; ALLERGEN; HOUSE DUST ALLERGEN; LEUKOTRIENE D4 RECEPTOR; LEUKOTRIENE RECEPTOR; PURINERGIC P2 RECEPTOR; RECOMBINANT PROTEIN;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BINDING COMPETITION; BRONCHUS HYPERREACTIVITY; CHO CELL; CONTROLLED STUDY; CYTOKINE PRODUCTION; EOSINOPHILIA; FEMALE; GENE EXPRESSION; GOBLET CELL; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; THROMBOCYTE; ANIMAL; BRONCHUS; CELL LINE; CRICETULUS; DRUG ANTAGONISM; HAMSTER; IMMUNOLOGY; MAST CELL; METABOLISM; METAPLASIA; PATHOLOGY; PNEUMONIA;

ALLERGENS; ANIMALS; ANTIGENS, DERMATOPHAGOIDES; BLOOD PLATELETS; BRONCHI; CELL LINE; CHO CELLS; CRICETINAE; CRICETULUS; GOBLET CELLS; HUMANS; LEUKOTRIENE E4; MAST CELLS; METAPLASIA; MICE; PNEUMONIA; RECEPTORS, LEUKOTRIENE; RECEPTORS, PURINERGIC P2; RECOMBINANT PROTEINS;

EID: 70449700139     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20091240     Document Type: Article

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