Potentiation of thromboxane A2-induced platelet secretion by Gi signaling through the phosphoinositide-3 kinase pathway

Thrombosis and Haemostasis

Volumn 85, Issue 2, 2001, Pages 341-348

  Dangelmaier, C ^a   Jin, J ^a   Smith, J B ^a   Kunapuli, S P ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ADP; Epinephrine; P2TAC receptor; Platelet activation

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 9 (TETRAHYDRO 2 FURYL)ADENINE; ADENOSINE 3' PHOSPHATE 5' PHOSPHATE; ADENOSINE DIPHOSPHATE; ADENYLATE CYCLASE; ALPHA 2A ADRENERGIC RECEPTOR; AR C 66096; CYCLIC AMP; FIBRINOGEN RECEPTOR ANTAGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PURINE P2 RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; SC 57101; THROMBOXANE A2; UNCLASSIFIED DRUG; WORTMANNIN; ADENOSINE TRIPHOSPHATE; ENZYME INHIBITOR; FIBRINOGEN RECEPTOR; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; SEROTONIN;

ARTICLE; DRUG ANTAGONISM; DRUG INHIBITION; DRUG POTENTIATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; METABOLIC ACTIVATION; NORMAL HUMAN; POSITIVE FEEDBACK; PRIORITY JOURNAL; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE RELEASE REACTION; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SECRETION; THROMBOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; 15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; BLOOD PLATELETS; CYCLIC AMP; ENZYME INHIBITORS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; RECEPTORS, PURINERGIC P2; SEROTONIN; SIGNAL TRANSDUCTION; THROMBOXANE A2;

EID: 0034746160     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1615690     Document Type: Article

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