Hippocampal glutamate level and glutamate aspartate transporter (GLAST) are up-regulated in senior rat associated with isoflurane-induced spatial learning/memory impairment

Neurochemical Research

Volumn 38, Issue 1, 2013, Pages 59-73

  Qu, Xiangdong ^a,b   Xu, Chengshi ^a   Wang, Hui ^a   Xu, Jie ^a   Liu, Weiran ^c   Wang, Yun ^a   Jia, Xingyuan ^d   Xie, Zhongcong ^e   Xu, Zhipeng ^e   Ji, Chao ^f   Wu, Anshi ^a   Yue, Yun ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Beijing Jishuitan Hospital   (China)

^c TIANJIN MEDICAL UNIVERSITY   (China)

^d CAPITAL MEDICAL UNIVERSITY   (China)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

^f PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Glutamate; Glutamate receptor; Glutamate transporter; Isoflurane; Learning memory impairment

Indexed keywords

AMPA RECEPTOR; EXCITATORY AMINO ACID TRANSPORTER; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMATE RECEPTOR; GLUTAMIC ACID; ISOFLURANE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; NO 26C 818A; TAU PROTEIN; UNCLASSIFIED DRUG;

AGED; ANESTHESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPOCAMPUS; INCIDENCE; LEARNING DISORDER; MALE; MAZE TEST; MEMORY DISORDER; MICRODIALYSIS; MORRIS WATER MAZE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPATIAL MEMORY; UPREGULATION; WESTERN BLOTTING;

AGING; ANESTHETICS, INHALATION; ANIMALS; BLOTTING, WESTERN; EXCITATORY AMINO ACID TRANSPORTER 1; EXCITATORY AMINO ACID TRANSPORTER 2; GLUTAMIC ACID; HIPPOCAMPUS; ISOFLURANE; LEARNING DISORDERS; MAZE LEARNING; MEMORY DISORDERS; MICRODIALYSIS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; RECEPTORS, N-METHYL-D-ASPARTATE; UP-REGULATION;

RATTUS;

EID: 84871618813     PISSN: 03643190     EISSN: 15736903     Source Type: Journal    
DOI: 10.1007/s11064-012-0889-8     Document Type: Article

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