Loss of Glial Glutamate and Aspartate Transporter (Excitatory Amino Acid Transporter 1) Causes Locomotor Hyperactivity and Exaggerated Responses to Psychotomimetics: Rescue by Haloperidol and Metabotropic Glutamate 2/3 Agonist

Biological Psychiatry

Volumn 64, Issue 9, 2008, Pages 810-814

  Karlsson, Rose Marie ^a   Tanaka, Kohichi ^b   Heilig, Markus ^a   Holmes, Andrew ^a  

^a NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

GLAST; glutamate; mGlu2 3; NMDA; schizophrenia

Indexed keywords

4 AMINO 2 OXABICYCLO[3.1.0]HEXANE 4,6 DICARBOXYLIC ACID; DIZOCILPINE; EXCITATORY AMINO ACID TRANSPORTER; HALOPERIDOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; GENOTYPE; HETEROZYGOSITY; HYPERACTIVITY; LOCOMOTION; MALE; MOUSE; NONHUMAN; POST HOC ANALYSIS; PRIORITY JOURNAL; SCHIZOPHRENIA; SEX DIFFERENCE;

AMINO ACIDS; ANALYSIS OF VARIANCE; ANIMALS; ANTI-DYSKINESIA AGENTS; BEHAVIOR, ANIMAL; BICYCLO COMPOUNDS, HETEROCYCLIC; DIZOCILPINE MALEATE; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY AMINO ACID TRANSPORTER 1; EXPLORATORY BEHAVIOR; HALOPERIDOL; HYPERKINESIS; LOCOMOTION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, METABOTROPIC GLUTAMATE;

EID: 53249142500     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biopsych.2008.05.001     Document Type: Article

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