Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain

Neurobiology of Disease

Volumn 21, Issue 3, 2006, Pages 522-530

  Yon, Jun Heum ^a,b   Carter, Lisa B ^a   Reiter, Russel J ^c   Jevtovic Todorovic, Vesna ^a  

^a UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^b Inje University College of Medicine   (South Korea)

^c Mays Cancer Center at UT Health San Antonio   (United States)

Author keywords

Apoptosis; bcl 2; Caspase; Cytochrome c; Mitochondria; Synaptogenesis

Indexed keywords

ANTIOXIDANT; CASPASE 3; CYTOCHROME C; DEOXYRIBONUCLEASE; ISOFLURANE; MELATONIN; MIDAZOLAM; NITROUS OXIDE; PROTEIN BCL XL;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; BRAIN REGION; DOSE RESPONSE; HOMEOSTASIS; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; THALAMUS ANTERIOR NUCLEUS; UPREGULATION;

ANESTHETICS, GENERAL; ANIMALS; APOPTOSIS; BCL-X PROTEIN; BLOTTING, WESTERN; BRAIN; CASPASE 3; CASPASES; CYTOCHROMES C; DOSE-RESPONSE RELATIONSHIP, DRUG; MELATONIN; MITOCHONDRIA; NERVE DEGENERATION; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33244492125     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2005.08.011     Document Type: Article

References (38)

1. D. Acuna-Castroviejo, M. Martin, M. Macias, G. Escames, J. Leon, H. Khaldy, and R.J. Reiter Melatonin, mitochondria, and cellular bioenergetics J. Pineal Res. 30 2001 65 74
2. S.A. Andrabi, I. Sayeed, D. Siemen, G. Wolf, and T.F. Horn Direct inhibition of the mitochondrial permeability transition pore: a possible mechanism responsible for anti-apoptotic effects of melatonin FASEB J. 18 2004 869 871
3. E. Bossy-Wetzel, D.D. Newmeyer, and D.R. Green Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization EMBO J. 17 1998 37 49
4. J.L. Daval, and P. Vert Apoptosis and neurogenesis after transient hypoxia in the developing rat brain Semin. Perinatol. 28 2004 257 263
5. J.S. DeOlmos, and W.R. Ingram An improved cupric-silver method for impregnation of axonal and terminal degeneration Brain Res. 33 1971 523 529
6. K. Dikranian, M.J. Ishimaru, T. Tenkova, J. Labruyere, Y.Q. Qin, C. Ikonomidou, and J.W. Olney Apoptosis in the in vivo mammalian forebrain Neurobiol. Dis. 8 2001 359 379
7. K. Dikranian, Y.Q. Qin, J. Labruyere, B. Nemmers, and J.W. Olney Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structures Brain Res. Dev. Brain Res. 155 2005 1 13
8. J. Dobbing, and J. Sands Comparative aspects of the brain growth spurt Early Hum. Dev. 3 1 1979 79 83
9. E. Gitto, M. Karbownik, R.J. Reiter, D.X. Tan, S. Cuzzocrea, P. Chiurazzi, S. Cordaro, G. Corona, G. Trimarchi, and I. Barberi Effects of melatonin treatment in septic newborns Pediatr. Res. 50 2001 756 760
10. E. Gitto, R.J. Reiter, S.P. Cordaro, M. La Rosa, P. Chiurazzi, G. Trimarchi, P. Gitto, M.P. Calabro, and I. Barberi Oxidative and inflammatory parameters in respiratory distress syndrome of preterm newborns: beneficial effects of melatonin Am. J. Perinatol. 21 2004 209 216
11. M.O. Hengartner The biochemistry of apoptosis Nature 407 2000 770 776
12. T.F. Hornbein, E.I. Eger, P.M. Winter, G. Smith, D. Wetstone, and K.H. Smith The minimum alveolar concentration of nitrous oxide in man Anesth. Analg. 61 1982 553 556
13. C. Ikonomidou, F. Bosch, M. Miksa, P. Bittigau, J. Vockler, K. Dikranian, T.I. Tenkova, V. Stefovska, L. Turski, and J.W. Olney Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain Science 283 1999 70 74
14. C. Ikonomidou, P. Bittigau, M.J. Ishimaru, D.F. Wozniak, C. Koch, K. Genz, M.T. Price, V. Stefovska, F. Horsters, T. Tenkova, K. Dikranian, and J.W. Olney Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome Science 287 2000 1056 1060
15. V. Jevtovic-Todorovic, S.M. Todorovic, S. Mennerick, S. Powell, K. Dikranian, N. Benshoff, C.F. Zorumski, and J.W. Olney Nitrous oxide (laughing gas) is an NMDA antagonist, neuroprotectant and neurotoxin Nat. Med. 4 1998 460 463
16. V. Jevtovic-Todorovic, N. Benshoff, and J.W. Olney Ketamine potentiates cerebrocortical damage induced by the common anaesthetic agent nitrous oxide in adult rats Br. J. Pharmacol. 130 2000 1692 1698
17. V. Jevtovic-Todorovic, D.W. Wozniak, N.D. Benshoff, and J.W. Olney Comparative evaluation of the neurotoxic properties of ketamine and nitrous oxide Brain Res. 895 2001 264 267
18. V. Jevtovic-Todorovic, R.E. Hartman, Y. Izumi, N.D. Benshoff, K. Dikranian, C.F. Zorumski, J.W. Olney, and D.F. Wozniak Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits J. Neurosci. 23 2003 876 882
19. V. Jevtovic-Todorovic, J. Beals, N. Benshoff, and J.W. Olney Prolonged exposure to inhalational anesthetic nitrous oxide kills neurons in adult rat brain Neuroscience 122 3 2003 609 616
20. M.J. Jou, T.I. Peng, R.J. Reiter, S.B. Jou, H.Y. Wu, and S.T. Wen Visualization of the antioxidative effects of melatonin at the mitochondrial level during oxidative stress-induced apoptosis of rat brain astrocytes J. Pineal Res. 37 2004 55 70
21. I. Kissin, P.T. Brown, and E.L. Bradley Jr. Sedative and hypnotic midazolam-morphine interactions in rats Anesth. Analg. 71 1990 137 143
22. J. Leon, D. Acuna-Castroviejo, G. Escames, D.X. Tan, and R.J. Reiter Melatonin mitigates mitochondrial malfunction J. Pineal Res. 38 2005 1 9
23. X. Lu, J.H. Yon, and V. Jevtovic-Todorovic Commonly-used anesthesia cocktail modulates the expression of brain-derived neurotrophic factor (BDNF) in the immature rat brain Abstr.-Soc. Neurosci. 2004 Program No. 39.12
24. N.W. Mahmoudi, D.J. Cole, and H.M. Shapiro Insufficient anesthetic potency of nitrous oxide in the rat Anesthesiology 70 1989 345 349
25. M. Martin, M. Macias, G. Escames, R.J. Reiter, M.T. Agapito, G.G. Ortiz, and D. Acuna-Castroviejo Melatonin-induced increased activity of the respiratory chain complexes I and IV can prevent mitochondrial damage induced by ruthenium red in vivo J. Pineal Res. 28 2000 242 248
26. A. Menendez-Pelaez, and R.J. Reiter Distribution of melatonin in mammalian tissues: the relative importance of nuclear versus cytosolic localization J. Pineal Res. 15 1993 59 69
27. M. Naguib, D.L. Hammond, P.G. Schmid III, M.T. Baker, J. Cutkomp, L. Queral, and T. Smith Pharmacological effects of intravenous melatonin: comparative studies with thiopental and propofol Br. J. Anaesth. 90 2003 504 507
28. G. Orliaguet, B. Vivien, O. Langeron, B. Bouhemad, P. Coriat, and B. Riou Minimum alveolar concentration of volatile anesthetics in rats during postnatal maturation Anesthesiology 95 2001 734 739
29. R.J. Reiter, D. Acuna-Castroviejo, D.X. Tan, and S. Burkhardt Free radical-mediated molecular damage. Mechanisms for the protective actions of melatonin in the central nervous system Ann. N. Y. Acad. Sci. 939 2001 200 215
30. R.J. Reiter, D.X. Tan, R.M. Sainz, J.C. Mayo, and S. Lopez-Burillo Melatonin: reducing the toxicity and increasing the efficacy of drugs J. Pharm. Pharmacol. 54 2002 1299 1321
31. S. Shavali, B. Ho, P. Govitrapong, S. Sawlom, A. Ajjimaporn, S. Klongpanichapak, and M. Ebadi Melatonin exerts its analgesic actions not by binding to opioid receptor subtypes but by increasing the release of beta-endorphin an endogenous opioid Brain Res. Bull. 64 2005 471 479
32. W.C. Stevens, and H.G.G. Kingston Inhalation anesthesia P.G. Barash B.F. Cullen R.K. Stoelting Clinical Anesthesia 1992 Philadelphia Lippincott, USA 385 412
33. G. Szalai, R. Krishnamurthy, and G. Hajnoczky Apoptosis driven by IP (3)-linked mitochondrial calcium signals EMBO J. 18 1999 6349 6361
34. P.A. Vitte, C. Harthe, P. Lestage, B. Claustrat, and P. Bobillier Plasma, cerebrospinal fluid, and brain distribution of 14C-melatonin in rat: a biochemical and autoradiographic study J. Pineal Res. 5 1988 437 453
35. M.J. West Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias Trends Neurosci. 22 1999 51 61
36. Yon, J.H., Daniel-Johnson, J., Carter, L.B., Jevtovic-Todorovic, V., in press. Anesthesia induces suicide in the developing rat brain via the intrinsic and extrinsic apoptotic pathways. Neuroscience.
37. Y.M. Yoo, S.V. Yim, S.S. Kim, H.Y. Jang, H.Z. Lea, G.C. Hwang, J.W. Kim, S.A. Kim, A.J. Lee, C.J. Kim, J.H. Chung, and K.H. Leem Melatonin suppresses NO-induced apoptosis via induction of Bcl-2 expression in PGT-β immortalized pineal cells J. Pineal Res. 33 2002 146
38. N. Zamzami, and G. Kroemer The mitochondrion in apoptosis: how Pandora's box opens Nat. Rev., Mol. Cell Biol. 2 2001 67 71