An emerging role of Sonic hedgehog shedding as a modulator of heparan sulfate interactions

Journal of Biological Chemistry

Volumn 287, Issue 52, 2012, Pages 43708-43719

  Ohlig, Stefanie ^a   Pickhinke, Ute ^a   Sirko, Svetlana ^b   Bandari, Shyam ^a   Hoffmann, Daniel ^c   Dreier, Rita ^a   Farshi, Pershang ^a   Götz, Magdalena ^b   Grobe, Kay ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING CAPACITIES; BRAIN SAMPLE; CELL FATE DECISION; CELL SURFACES; EXTRACELLULAR MATRICES; HEPARAN SULFATES; IN-VITRO; IN-VIVO; INVERTEBRATE TISSUES; LIPIDATED PROTEINS; LOCAL SOURCE; LONG RANGE; MORPHOGENS; N-TERMINALS; PROCESSING TARGETS; PROTEIN CLUSTERS; PROTEOGLYCANS; PROTEOLYTIC PROCESSING; RECEPTOR BINDING SITE; SONIC HEDGEHOGS; TARGET CELLS;

AMINO ACIDS; CELL MEMBRANES; PEPTIDES; SOLUBILITY; TISSUE;

BIOSYNTHESIS;

HEPARAN SULFATE; MORPHOGEN; PROTEOGLYCAN; SONIC HEDGEHOG PROTEIN;

AMINO TERMINAL SEQUENCE; ANIMAL TISSUE; ARTICLE; BIOLOGICAL ACTIVITY; CELL SURFACE; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN IMMOBILIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION;

AMINO ACID MOTIFS; ANIMALS; BINDING SITES; BRAIN; CELL LINE; EXTRACELLULAR MATRIX; HEDGEHOG PROTEINS; HEPARITIN SULFATE; HUMANS; LIPOYLATION; MICE; NERVE TISSUE PROTEINS; RECEPTORS, CELL SURFACE;

ERINACEIDAE; INVERTEBRATA; MURINAE; VERTEBRATA;

EID: 84871596524     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.356667     Document Type: Article

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