Scube/You activity mediates release of dually lipid-modified Hedgehog signal in soluble form

Genes and Development

Volumn 26, Issue 12, 2012, Pages 1312-1325

  Creanga, Adrian ^a,b,c   Glenn, Thomas D ^b   Mann, Randall K ^a,b   Saunders, Adam M ^a,b   Talbot, William S ^b   Beachy, Philip A ^a,b,c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b STANFORD UNIVERSITY   (United States)

^c DEPARTMENT OF PATHOLOGY   (United States)

Author keywords

Dispatcheda; Hedgehog; Morphogen release; Palmitate; Scube2

Indexed keywords

CHOLESTEROL; DISPATCHEDA PROTEIN; LIPID; MEMBRANE PROTEIN; PALMITIC ACID; PROTEIN; SCUBE2 PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; EMBRYO; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN STABILITY; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; ZEBRA FISH;

ANIMALS; CELL-FREE SYSTEM; CELLS, CULTURED; CHOLESTEROL; CULTURE MEDIA; DETERGENTS; HEDGEHOG PROTEINS; HEK293 CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIPID METABOLISM; MEMBRANE MICRODOMAINS; MEMBRANE PROTEINS; MICE; PALMITATES; PROTEIN BINDING; PROTEIN STABILITY; SIGNAL TRANSDUCTION; SOLUBILITY; STRUCTURE-ACTIVITY RELATIONSHIP; ZEBRAFISH;

EID: 84862594879     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.191866.112     Document Type: Article

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