-
1
-
-
33244485265
-
The interpretation of morphogen gradients
-
Ashe H.L., Briscoe J. The interpretation of morphogen gradients. Development 2006, 133:385-394.
-
(2006)
Development
, vol.133
, pp. 385-394
-
-
Ashe, H.L.1
Briscoe, J.2
-
2
-
-
0028329349
-
Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein
-
Basler K., Struhl G. Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein. Nature 1994, 368:208-214.
-
(1994)
Nature
, vol.368
, pp. 208-214
-
-
Basler, K.1
Struhl, G.2
-
3
-
-
9244221172
-
Tissue repair and stem cell renewal in carcinogenesis
-
Beachy P.A., Karhadkar S.S., Berman D.M. Tissue repair and stem cell renewal in carcinogenesis. Nature 2004, 432:324-331.
-
(2004)
Nature
, vol.432
, pp. 324-331
-
-
Beachy, P.A.1
Karhadkar, S.S.2
Berman, D.M.3
-
4
-
-
5444233782
-
Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans
-
Belenkaya T.Y., Han C., Yan D., Opoka R.J., Khodoun M., Liu H., Lin X. Drosophila Dpp morphogen movement is independent of dynamin-mediated endocytosis but regulated by the glypican members of heparan sulfate proteoglycans. Cell 2004, 119:231-244.
-
(2004)
Cell
, vol.119
, pp. 231-244
-
-
Belenkaya, T.Y.1
Han, C.2
Yan, D.3
Opoka, R.J.4
Khodoun, M.5
Liu, H.6
Lin, X.7
-
5
-
-
0027160708
-
Targeted gene expression as a means of altering cell fates and generating dominant phenotypes
-
Brand A.H., Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 1993, 118:401-415.
-
(1993)
Development
, vol.118
, pp. 401-415
-
-
Brand, A.H.1
Perrimon, N.2
-
6
-
-
33244463974
-
Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix
-
Published online January 5, 2006
-
Callejo A., Torroja C., Quijada L., Guerrero I. Hedgehog lipid modifications are required for Hedgehog stabilization in the extracellular matrix. Development 2006, 133:471-483. Published online January 5, 2006. 10.1242/dev.02217.
-
(2006)
Development
, vol.133
, pp. 471-483
-
-
Callejo, A.1
Torroja, C.2
Quijada, L.3
Guerrero, I.4
-
7
-
-
0037125938
-
Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling
-
Caspary T., Garcia-Garcia M.J., Huangfu D., Eggenschwiler J.T., Wyler M.R., Rakeman A.S., Alcorn H.L., Anderson K.V. Mouse Dispatched homolog1 is required for long-range, but not juxtacrine, Hh signaling. Curr. Biol. 2002, 12:1628-1632.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1628-1632
-
-
Caspary, T.1
Garcia-Garcia, M.J.2
Huangfu, D.3
Eggenschwiler, J.T.4
Wyler, M.R.5
Rakeman, A.S.6
Alcorn, H.L.7
Anderson, K.V.8
-
8
-
-
42549109108
-
Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning
-
Published online February 13, 2008
-
Chamberlain C.E., Jeong J., Guo C., Allen B.L., McMahon A.P. Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning. Development 2008, 135:1097-1106. Published online February 13, 2008. 10.1242/dev.013086.
-
(2008)
Development
, vol.135
, pp. 1097-1106
-
-
Chamberlain, C.E.1
Jeong, J.2
Guo, C.3
Allen, B.L.4
McMahon, A.P.5
-
9
-
-
0030297553
-
Dual roles for patched in sequestering and transducing Hedgehog
-
Chen Y., Struhl G. Dual roles for patched in sequestering and transducing Hedgehog. Cell 1996, 87:553-563.
-
(1996)
Cell
, vol.87
, pp. 553-563
-
-
Chen, Y.1
Struhl, G.2
-
10
-
-
4444227277
-
Patterns in evolution: veins of the Drosophila wing
-
Crozatier M., Glise B., Vincent A. Patterns in evolution: veins of the Drosophila wing. Trends Genet. 2004, 20:498-505.
-
(2004)
Trends Genet.
, vol.20
, pp. 498-505
-
-
Crozatier, M.1
Glise, B.2
Vincent, A.3
-
11
-
-
33646914937
-
Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord
-
Danesin C., Agius E., Escalas N., Ai X., Emerson C., Cochard P., Soula C. Ventral neural progenitors switch toward an oligodendroglial fate in response to increased Sonic hedgehog (Shh) activity: involvement of Sulfatase 1 in modulating Shh signaling in the ventral spinal cord. J. Neurosci. 2006, 26:5037-5048.
-
(2006)
J. Neurosci.
, vol.26
, pp. 5037-5048
-
-
Danesin, C.1
Agius, E.2
Escalas, N.3
Ai, X.4
Emerson, C.5
Cochard, P.6
Soula, C.7
-
12
-
-
30644469247
-
Release and trafficking of lipid-linked morphogens
-
Published online December 20, 2005
-
Eaton S. Release and trafficking of lipid-linked morphogens. Curr. Opin. Genet. Dev. 2006, 16:17-22. Published online December 20, 2005. 10.1016/j.gde.2005.12.006.
-
(2006)
Curr. Opin. Genet. Dev.
, vol.16
, pp. 17-22
-
-
Eaton, S.1
-
14
-
-
34250870665
-
Lipoprotein-heparan sulfate interactions in the Hh pathway
-
Eugster C., Panakova D., Mahmoud A., Eaton S. Lipoprotein-heparan sulfate interactions in the Hh pathway. Dev. Cell 2007, 13:57-71.
-
(2007)
Dev. Cell
, vol.13
, pp. 57-71
-
-
Eugster, C.1
Panakova, D.2
Mahmoud, A.3
Eaton, S.4
-
15
-
-
14844360345
-
Glypicans shunt the Wingless signal between local signalling and further transport
-
Published online January 12, 2005
-
Franch-Marro X., Marchand O., Piddini E., Ricardo S., Alexandre C., Vincent J.P. Glypicans shunt the Wingless signal between local signalling and further transport. Development 2005, 132:659-666. Published online January 12, 2005. 10.1242/dev.01639.
-
(2005)
Development
, vol.132
, pp. 659-666
-
-
Franch-Marro, X.1
Marchand, O.2
Piddini, E.3
Ricardo, S.4
Alexandre, C.5
Vincent, J.P.6
-
16
-
-
9644264342
-
Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment
-
Gallet A., Therond P.P. Temporal modulation of the Hedgehog morphogen gradient by a patched-dependent targeting to lysosomal compartment. Dev. Biol. 2005, 277:51-62.
-
(2005)
Dev. Biol.
, vol.277
, pp. 51-62
-
-
Gallet, A.1
Therond, P.P.2
-
17
-
-
0037321854
-
Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog
-
Gallet A., Rodriguez R., Ruel L., Therond P.P. Cholesterol modification of hedgehog is required for trafficking and movement, revealing an asymmetric cellular response to hedgehog. Dev. Cell 2003, 4:191-204.
-
(2003)
Dev. Cell
, vol.4
, pp. 191-204
-
-
Gallet, A.1
Rodriguez, R.2
Ruel, L.3
Therond, P.P.4
-
18
-
-
33244482560
-
Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia
-
Published online January 5, 2006
-
Gallet A., Ruel L., Staccini-Lavenant L., Therond P.P. Cholesterol modification is necessary for controlled planar long-range activity of Hedgehog in Drosophila epithelia. Development 2006, 133:407-418. Published online January 5, 2006. 10.1242/dev.02212.
-
(2006)
Development
, vol.133
, pp. 407-418
-
-
Gallet, A.1
Ruel, L.2
Staccini-Lavenant, L.3
Therond, P.P.4
-
19
-
-
43049138477
-
Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis
-
Gallet A., Staccini-Lavenant L., Therond P.P. Cellular trafficking of the glypican Dally-like is required for full-strength Hedgehog signaling and wingless transcytosis. Dev. Cell 2008, 14:712-725.
-
(2008)
Dev. Cell
, vol.14
, pp. 712-725
-
-
Gallet, A.1
Staccini-Lavenant, L.2
Therond, P.P.3
-
20
-
-
0036570660
-
Wingful, an extracellular feedback inhibitor of Wingless
-
Gerlitz O., Basler K. Wingful, an extracellular feedback inhibitor of Wingless. Genes Dev. 2002, 16:1055-1059.
-
(2002)
Genes Dev.
, vol.16
, pp. 1055-1059
-
-
Gerlitz, O.1
Basler, K.2
-
21
-
-
0036744788
-
Lumenal transmission of decapentaplegic in Drosophila imaginal discs
-
Gibson M.C., Lehman D.A., Schubiger G. Lumenal transmission of decapentaplegic in Drosophila imaginal discs. Dev. Cell 2002, 3:451-460.
-
(2002)
Dev. Cell
, vol.3
, pp. 451-460
-
-
Gibson, M.C.1
Lehman, D.A.2
Schubiger, G.3
-
22
-
-
0036111641
-
HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient
-
Giraldez A.J., Copley R.R., Cohen S.M. HSPG modification by the secreted enzyme Notum shapes the Wingless morphogen gradient. Dev. Cell 2002, 2:667-676.
-
(2002)
Dev. Cell
, vol.2
, pp. 667-676
-
-
Giraldez, A.J.1
Copley, R.R.2
Cohen, S.M.3
-
23
-
-
0035881919
-
The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides
-
Gritli-Linde A., Lewis P., McMahon A.P., Linde A. The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev. Biol. 2001, 236:364-386.
-
(2001)
Dev. Biol.
, vol.236
, pp. 364-386
-
-
Gritli-Linde, A.1
Lewis, P.2
McMahon, A.P.3
Linde, A.4
-
24
-
-
0035950105
-
Morphogen gradient interpretation
-
Gurdon J.B., Bourillot P.Y. Morphogen gradient interpretation. Nature 2001, 413:797-803.
-
(2001)
Nature
, vol.413
, pp. 797-803
-
-
Gurdon, J.B.1
Bourillot, P.Y.2
-
25
-
-
1242329977
-
Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process
-
Published online January 7, 2004
-
Han C., Belenkaya T.Y., Wang B., Lin X. Drosophila glypicans control the cell-to-cell movement of Hedgehog by a dynamin-independent process. Development 2004, 131:601-611. Published online January 7, 2004. 10.1242/dev.00958.
-
(2004)
Development
, vol.131
, pp. 601-611
-
-
Han, C.1
Belenkaya, T.Y.2
Wang, B.3
Lin, X.4
-
26
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang J., Hui C.C. Hedgehog signaling in development and cancer. Dev. Cell 2008, 15:801-812.
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.C.2
-
27
-
-
0033636788
-
In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration
-
Johnson R.L., Milenkovic L., Scott M.P. In vivo functions of the patched protein: requirement of the C terminus for target gene inactivation but not Hedgehog sequestration. Mol. Cell 2000, 6:467-478.
-
(2000)
Mol. Cell
, vol.6
, pp. 467-478
-
-
Johnson, R.L.1
Milenkovic, L.2
Scott, M.P.3
-
28
-
-
0036922902
-
Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling
-
Kawakami T., Kawcak T., Li Y.J., Zhang W., Hu Y., Chuang P.T., Caspary T., Garcia-Garcia M.J., Huangfu D., Eggenschwiler J.T., et al. Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development 2002, 129:5753-5765.
-
(2002)
Development
, vol.129
, pp. 5753-5765
-
-
Kawakami, T.1
Kawcak, T.2
Li, Y.J.3
Zhang, W.4
Hu, Y.5
Chuang, P.T.6
Caspary, T.7
Garcia-Garcia, M.J.8
Huangfu, D.9
Eggenschwiler, J.T.10
-
29
-
-
35148883003
-
Tgf-β signaling in development
-
Kitisin K., Saha T., Blake T., Golestaneh N., Deng M., Kim C., Tang Y., Shetty K., Mishra B., Mishra L. Tgf-β signaling in development. Sci. STKE 2007, 2007:cm1.
-
(2007)
Sci. STKE
, vol.2007
-
-
Kitisin, K.1
Saha, T.2
Blake, T.3
Golestaneh, N.4
Deng, M.5
Kim, C.6
Tang, Y.7
Shetty, K.8
Mishra, B.9
Mishra, L.10
-
30
-
-
5044249440
-
Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity
-
Kreuger J., Perez L., Giraldez A.J., Cohen S.M. Opposing activities of Dally-like glypican at high and low levels of Wingless morphogen activity. Dev. Cell 2004, 7:503-512.
-
(2004)
Dev. Cell
, vol.7
, pp. 503-512
-
-
Kreuger, J.1
Perez, L.2
Giraldez, A.J.3
Cohen, S.M.4
-
31
-
-
33745280126
-
The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans
-
Liegeois S., Benedetto A., Garnier J.M., Schwab Y., Labouesse M. The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans. J. Cell Biol. 2006, 173:949-961.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 949-961
-
-
Liegeois, S.1
Benedetto, A.2
Garnier, J.M.3
Schwab, Y.4
Labouesse, M.5
-
32
-
-
12344310615
-
Functions of heparan sulfate proteoglycans in cell signaling during development
-
Lin X. Functions of heparan sulfate proteoglycans in cell signaling during development. Development 2004, 131:6009-6021.
-
(2004)
Development
, vol.131
, pp. 6009-6021
-
-
Lin, X.1
-
33
-
-
0037020216
-
Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched
-
Ma Y., Erkner A., Gong R., Yao S., Taipale J., Basler K., Beachy P.A. Hedgehog-mediated patterning of the mammalian embryo requires transporter-like function of dispatched. Cell 2002, 111:63-75.
-
(2002)
Cell
, vol.111
, pp. 63-75
-
-
Ma, Y.1
Erkner, A.2
Gong, R.3
Yao, S.4
Taipale, J.5
Basler, K.6
Beachy, P.A.7
-
34
-
-
67650230896
-
Wnt/β-catenin signaling: components, mechanisms, and diseases
-
MacDonald B.T., Tamai K., He X. Wnt/β-catenin signaling: components, mechanisms, and diseases. Dev. Cell 2009, 17:9-26.
-
(2009)
Dev. Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
35
-
-
30644480899
-
The endocytic pathway and formation of the Wingless morphogen gradient
-
Published online December 14, 2005
-
Marois E., Mahmoud A., Eaton S. The endocytic pathway and formation of the Wingless morphogen gradient. Development 2006, 133:307-317. Published online December 14, 2005. 10.1242/dev.02197.
-
(2006)
Development
, vol.133
, pp. 307-317
-
-
Marois, E.1
Mahmoud, A.2
Eaton, S.3
-
36
-
-
0034699331
-
CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells
-
Michaux G., Gansmuller A., Hindelang C., Labouesse M. CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells. Curr. Biol. 2000, 10:1098-1107.
-
(2000)
Curr. Biol.
, vol.10
, pp. 1098-1107
-
-
Michaux, G.1
Gansmuller, A.2
Hindelang, C.3
Labouesse, M.4
-
37
-
-
0032759039
-
Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo
-
Moline M.M., Southern C., Bejsovec A. Directionality of wingless protein transport influences epidermal patterning in the Drosophila embryo. Development 1999, 126:4375-4384.
-
(1999)
Development
, vol.126
, pp. 4375-4384
-
-
Moline, M.M.1
Southern, C.2
Bejsovec, A.3
-
38
-
-
1942425465
-
Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo
-
Nakano Y., Kim H.R., Kawakami A., Roy S., Schier A.F., Ingham P.W. Inactivation of dispatched 1 by the chameleon mutation disrupts Hedgehog signalling in the zebrafish embryo. Dev. Biol. 2004, 269:381-392.
-
(2004)
Dev. Biol.
, vol.269
, pp. 381-392
-
-
Nakano, Y.1
Kim, H.R.2
Kawakami, A.3
Roy, S.4
Schier, A.F.5
Ingham, P.W.6
-
39
-
-
58249137165
-
Interpretation of the wingless gradient requires signaling-induced self-inhibition
-
Piddini E., Vincent J.P. Interpretation of the wingless gradient requires signaling-induced self-inhibition. Cell 2009, 136:296-307.
-
(2009)
Cell
, vol.136
, pp. 296-307
-
-
Piddini, E.1
Vincent, J.P.2
-
40
-
-
0034704824
-
Wingless gradient formation in the Drosophila wing
-
Strigini M., Cohen S.M. Wingless gradient formation in the Drosophila wing. Curr. Biol. 2000, 10:293-300.
-
(2000)
Curr. Biol.
, vol.10
, pp. 293-300
-
-
Strigini, M.1
Cohen, S.M.2
-
41
-
-
0035901572
-
Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation
-
Strutt H., Thomas C., Nakano Y., Stark D., Neave B., Taylor A.M., Ingham P.W. Mutations in the sterol-sensing domain of Patched suggest a role for vesicular trafficking in Smoothened regulation. Curr. Biol. 2001, 11:608-613.
-
(2001)
Curr. Biol.
, vol.11
, pp. 608-613
-
-
Strutt, H.1
Thomas, C.2
Nakano, Y.3
Stark, D.4
Neave, B.5
Taylor, A.M.6
Ingham, P.W.7
-
42
-
-
34249798211
-
Quantitative analysis of Hedgehog gradient formation using an inducible expression system
-
Su V.F., Jones K.A., Brodsky M., The I. Quantitative analysis of Hedgehog gradient formation using an inducible expression system. BMC Dev. Biol. 2007, 7:43.
-
(2007)
BMC Dev. Biol.
, vol.7
, pp. 43
-
-
Su, V.F.1
Jones, K.A.2
Brodsky, M.3
The, I.4
-
43
-
-
23244466312
-
Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog
-
Takeo S., Akiyama T., Firkus C., Aigaki T., Nakato H. Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog. Dev. Biol. 2005, 284:204-218.
-
(2005)
Dev. Biol.
, vol.284
, pp. 204-218
-
-
Takeo, S.1
Akiyama, T.2
Firkus, C.3
Aigaki, T.4
Nakato, H.5
-
44
-
-
0033636094
-
Dpp gradient formation in the Drosophila wing imaginal disc
-
Teleman A.A., Cohen S.M. Dpp gradient formation in the Drosophila wing imaginal disc. Cell 2000, 103:971-980.
-
(2000)
Cell
, vol.103
, pp. 971-980
-
-
Teleman, A.A.1
Cohen, S.M.2
-
45
-
-
3042799334
-
Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction
-
Published online April 21, 2004
-
Torroja C., Gorfinkiel N., Guerrero I. Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction. Development 2004, 131:2395-2408. Published online April 21, 2004. 10.1242/dev.01102.
-
(2004)
Development
, vol.131
, pp. 2395-2408
-
-
Torroja, C.1
Gorfinkiel, N.2
Guerrero, I.3
-
46
-
-
41149161142
-
Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface
-
Traister A., Shi W., Filmus J. Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface. Biochem. J. 2008, 410:503-511.
-
(2008)
Biochem. J.
, vol.410
, pp. 503-511
-
-
Traister, A.1
Shi, W.2
Filmus, J.3
-
47
-
-
51949085076
-
Hedgehog: functions and mechanisms
-
Varjosalo M., Taipale J. Hedgehog: functions and mechanisms. Genes Dev. 2008, 22:2454-2472.
-
(2008)
Genes Dev.
, vol.22
, pp. 2454-2472
-
-
Varjosalo, M.1
Taipale, J.2
-
48
-
-
45449112808
-
Nanoscale organization of hedgehog is essential for long-range signaling
-
Vyas N., Goswami D., Manonmani A., Sharma P., Ranganath H.A., VijayRaghavan K., Shashidhara L.S., Sowdhamini R., Mayor S. Nanoscale organization of hedgehog is essential for long-range signaling. Cell 2008, 133:1214-1227.
-
(2008)
Cell
, vol.133
, pp. 1214-1227
-
-
Vyas, N.1
Goswami, D.2
Manonmani, A.3
Sharma, P.4
Ranganath, H.A.5
VijayRaghavan, K.6
Shashidhara, L.S.7
Sowdhamini, R.8
Mayor, S.9
-
49
-
-
0141594935
-
From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family
-
Waite K.A., Eng C. From developmental disorder to heritable cancer: it's all in the BMP/TGF-β family. Nat. Rev. Genet. 2003, 4:763-773.
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 763-773
-
-
Waite, K.A.1
Eng, C.2
-
50
-
-
0027267041
-
Analysis of genetic mosaics in developing and adult Drosophila tissues
-
Xu T., Rubin G.M. Analysis of genetic mosaics in developing and adult Drosophila tissues. Development 1993, 117:1223-1237.
-
(1993)
Development
, vol.117
, pp. 1223-1237
-
-
Xu, T.1
Rubin, G.M.2
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