메뉴 건너뛰기




Volumn 107, Issue 1, 2013, Pages 8-14

Molecular pathways in pancreatic carcinogenesis

Author keywords

cystic neoplasm; GNAS; pancreatic cancer; RNF43

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; MIXED LINEAGE LEUKEMIA PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN P53; RAF PROTEIN; RAS PROTEIN; RING FINGER PROTEIN; SMAD4 PROTEIN; VON HIPPEL LINDAU PROTEIN;

EID: 84871312925     PISSN: 00224790     EISSN: 10969098     Source Type: Journal    
DOI: 10.1002/jso.23213     Document Type: Article
Times cited : (75)

References (62)
  • 2
    • 0036883940 scopus 로고    scopus 로고
    • Pancreatic cancer biology and genetics
    • Bardeesy N, DePinho RA:, Pancreatic cancer biology and genetics. Nat Rev Cancer 2002; 2: 897-909.
    • (2002) Nat Rev Cancer , vol.2 , pp. 897-909
    • Bardeesy, N.1    Depinho, R.2
  • 4
    • 0035020633 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions
    • Hruban RH, Adsay NV, Albores-Saavedra J, et al.: Pancreatic intraepithelial neoplasia: A new nomenclature and classification system for pancreatic duct lesions. Am J Surg Pathol 2001; 25: 579-586.
    • (2001) Am J Surg Pathol , vol.25 , pp. 579-586
    • Hruban, R.H.1    Adsay, N.V.2    Albores-Saavedra, J.3
  • 6
    • 3242744313 scopus 로고    scopus 로고
    • An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms
    • Hruban RH, Takaori K, Klimstra DS, et al.: An illustrated consensus on the classification of pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasms. Am J Surg Pathol 2004; 28: 977-987.
    • (2004) Am J Surg Pathol , vol.28 , pp. 977-987
    • Hruban, R.H.1    Takaori, K.2    Klimstra, D.S.3
  • 7
    • 79953795493 scopus 로고    scopus 로고
    • Cystic lesions of the pancreas: Changes in the presentation and management of 1,424 patients at a single institution over a 15-year time period
    • Gaujoux S, Brennan MF, Gonen M, et al.: Cystic lesions of the pancreas: Changes in the presentation and management of 1,424 patients at a single institution over a 15-year time period. J Am Coll Surg 2011; 212: 590-600; discussion 600-603.
    • (2011) J Am Coll Surg , vol.212 , pp. 590-600
    • Gaujoux, S.1    Brennan, M.F.2    Gonen, M.3
  • 8
    • 17144364694 scopus 로고    scopus 로고
    • Precursors to invasive pancreatic cancer
    • Maitra A, Fukushima N, Takaori K, et al.: Precursors to invasive pancreatic cancer. Adv Anat Pathol 2005; 12: 81-91.
    • (2005) Adv Anat Pathol , vol.12 , pp. 81-91
    • Maitra, A.1    Fukushima, N.2    Takaori, K.3
  • 9
    • 0036841802 scopus 로고    scopus 로고
    • Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia
    • van Heek NT, Meeker AK, Kern SE, et al.: Telomere shortening is nearly universal in pancreatic intraepithelial neoplasia. Am J Pathol 2002; 161: 1541-1547.
    • (2002) Am J Pathol , vol.161 , pp. 1541-1547
    • Van Heek, N.T.1    Meeker, A.K.2    Kern, S.E.3
  • 10
    • 84862777152 scopus 로고    scopus 로고
    • Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia
    • Kanda M, Matthaei H, Wu J, et al.: Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. Gastroenterology 2012; 142: 730-733.
    • (2012) Gastroenterology , vol.142 , pp. 730-733
    • Kanda, M.1    Matthaei, H.2    Wu, J.3
  • 11
    • 0029125820 scopus 로고
    • K-ras mutation and pancreatic adenocarcinoma
    • Caldas C, Kern SE:, K-ras mutation and pancreatic adenocarcinoma. Int J Pancreatol 1995; 18: 1-6.
    • (1995) Int J Pancreatol , vol.18 , pp. 1-6
    • Caldas, C.1    Kern, S.2
  • 12
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • Schubbert S, Shannon K, Bollag G:, Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007; 7: 295-308.
    • (2007) Nat Rev Cancer , vol.7 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 13
    • 0141425732 scopus 로고    scopus 로고
    • BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: Potential therapeutic targets
    • Calhoun ES, Jones JB, Ashfaq R, et al.: BRAF and FBXW7 (CDC4, FBW7, AGO, SEL10) mutations in distinct subsets of pancreatic cancer: Potential therapeutic targets. Am J Pathol 2003; 163: 1255-1260.
    • (2003) Am J Pathol , vol.163 , pp. 1255-1260
    • Calhoun, E.S.1    Jones, J.B.2    Ashfaq, R.3
  • 14
    • 16944367477 scopus 로고    scopus 로고
    • Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas
    • Schutte M, Hruban RH, Geradts J, et al.: Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas. Cancer Res 1997; 57: 3126-3130.
    • (1997) Cancer Res , vol.57 , pp. 3126-3130
    • Schutte, M.1    Hruban, R.H.2    Geradts, J.3
  • 15
    • 0028059330 scopus 로고
    • Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
    • Caldas C, Hahn SA, da Costa LT:, Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994; 8: 27-32.
    • (1994) Nat Genet , vol.8 , pp. 27-32
    • Caldas, C.1    Hahn, S.A.2    Da Costa, L.3
  • 16
    • 82755186408 scopus 로고    scopus 로고
    • Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence
    • Larsson LG:, Oncogene- and tumor suppressor gene-mediated suppression of cellular senescence. Semin Cancer Biol 2011; 21: 367-376.
    • (2011) Semin Cancer Biol , vol.21 , pp. 367-376
    • Larsson, L.1
  • 17
    • 14444284330 scopus 로고    scopus 로고
    • Tumor-suppressive pathways in pancreatic carcinoma
    • Rozenblum E, Schutte M, Goggins M, et al.: Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 1997; 57: 1731-1734.
    • (1997) Cancer Res , vol.57 , pp. 1731-1734
    • Rozenblum, E.1    Schutte, M.2    Goggins, M.3
  • 18
    • 33750030758 scopus 로고    scopus 로고
    • The regulation of INK4/ARF in cancer and aging
    • Kim WY, Sharpless NE:, The regulation of INK4/ARF in cancer and aging. Cell 2006; 127: 265-275.
    • (2006) Cell , vol.127 , pp. 265-275
    • Kim, W.Y.1    Sharpless, N.2
  • 19
    • 0028970946 scopus 로고
    • P53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma
    • DiGiuseppe JA:, Redston MS, Yeo CJ, et al.: p53-independent expression of the cyclin-dependent kinase inhibitor p21 in pancreatic carcinoma. Am J Pathol 1995; 147: 884-888.
    • (1995) Am J Pathol , vol.147 , pp. 884-888
    • Digiuseppe, J.1    Redston, M.S.2    Yeo, C.J.3
  • 20
    • 52149123619 scopus 로고    scopus 로고
    • Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
    • Jones S, Zhang X, Parsons DW, et al.: Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 2008; 321: 1801-1806.
    • (2008) Science , vol.321 , pp. 1801-1806
    • Jones, S.1    Zhang, X.2    Parsons, D.W.3
  • 21
    • 0028308492 scopus 로고
    • P53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions
    • Redston MS, Caldas C, Seymour AB, et al.: p53 mutations in pancreatic carcinoma and evidence of common involvement of homocopolymer tracts in DNA microdeletions. Cancer Res 1994; 54: 3025-3033.
    • (1994) Cancer Res , vol.54 , pp. 3025-3033
    • Redston, M.S.1    Caldas, C.2    Seymour, A.B.3
  • 22
    • 4043181214 scopus 로고    scopus 로고
    • Cancer genes and the pathways they control
    • Vogelstein B, Kinzler KW:, Cancer genes and the pathways they control. Nat Med 2004; 10: 789-799.
    • (2004) Nat Med , vol.10 , pp. 789-799
    • Vogelstein, B.1    Kinzler, K.2
  • 23
    • 0034032009 scopus 로고    scopus 로고
    • Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression
    • Wilentz RE, Iacobuzio-Donahue CA, Argani P, et al.: Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: Evidence that DPC4 inactivation occurs late in neoplastic progression. Cancer Res 2000; 60: 2002-2006.
    • (2000) Cancer Res , vol.60 , pp. 2002-2006
    • Wilentz, R.E.1    Iacobuzio-Donahue, C.A.2    Argani, P.3
  • 24
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al.: DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-353.
    • (1996) Science , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 25
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • Siegel PM, Massague J:, Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-821.
    • (2003) Nat Rev Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 26
    • 0033573825 scopus 로고    scopus 로고
    • G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: Phenotypes reversed by a tumorigenic mutation
    • Dai JL, Bansal RK, Kern SE:, G1 cell cycle arrest and apoptosis induction by nuclear Smad4/Dpc4: Phenotypes reversed by a tumorigenic mutation. Proc Natl Acad Sci USA 1999; 96: 1427-1432.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 1427-1432
    • Dai, J.L.1    Bansal, R.K.2    Kern, S.3
  • 27
    • 0035671396 scopus 로고    scopus 로고
    • The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma
    • Tascilar M, Skinner HG, Rosty C, et al.: The SMAD4 protein and prognosis of pancreatic ductal adenocarcinoma. Clin Cancer Res 2001; 7: 4115-4121.
    • (2001) Clin Cancer Res , vol.7 , pp. 4115-4121
    • Tascilar, M.1    Skinner, H.G.2    Rosty, C.3
  • 28
    • 62249176551 scopus 로고    scopus 로고
    • DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer
    • Iacobuzio-Donahue CA, Fu B, Yachida S, et al.: DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer. J Clin Oncol 2009; 27: 1806-1813.
    • (2009) J Clin Oncol , vol.27 , pp. 1806-1813
    • Iacobuzio-Donahue, C.A.1    Fu, B.2    Yachida, S.3
  • 29
    • 0032404111 scopus 로고    scopus 로고
    • Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas
    • Goggins M, Shekher M, Turnacioglu K, et al.: Genetic alterations of the transforming growth factor beta receptor genes in pancreatic and biliary adenocarcinomas. Cancer Res 1998; 58: 5329-5332.
    • (1998) Cancer Res , vol.58 , pp. 5329-5332
    • Goggins, M.1    Shekher, M.2    Turnacioglu, K.3
  • 30
    • 36248962105 scopus 로고    scopus 로고
    • The genomic landscapes of human breast and colorectal cancers
    • Wood LD, Parsons DW, Jones S, et al.: The genomic landscapes of human breast and colorectal cancers. Science 2007; 318: 1108-1113.
    • (2007) Science , vol.318 , pp. 1108-1113
    • Wood, L.D.1    Parsons, D.W.2    Jones, S.3
  • 31
    • 77957731999 scopus 로고    scopus 로고
    • Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma
    • Jones S, Wang TL, Shih Ie M, et al.: Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma. Science 2010; 330: 228-231.
    • (2010) Science , vol.330 , pp. 228-231
    • Jones, S.1    Wang, T.L.2    Shih Ie, M.3
  • 32
    • 84857467474 scopus 로고    scopus 로고
    • Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
    • Jones S, Li M, Parsons DW, et al.: Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum Mutat 2012; 33: 100-103.
    • (2012) Hum Mutat , vol.33 , pp. 100-103
    • Jones, S.1    Li, M.2    Parsons, D.W.3
  • 33
    • 84857129204 scopus 로고    scopus 로고
    • Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer
    • Shain AH, Giacomini CP, Matsukuma K, et al.: Convergent structural alterations define SWItch/Sucrose NonFermentable (SWI/SNF) chromatin remodeler as a central tumor suppressive complex in pancreatic cancer. Proc Natl Acad Sci USA 2012; 109: E252-E259.
    • (2012) Proc Natl Acad Sci USA , vol.109
    • Shain, A.H.1    Giacomini, C.P.2    Matsukuma, K.3
  • 34
    • 7444246651 scopus 로고    scopus 로고
    • Two related ARID family proteins are alternative subunits of human SWI/SNF complexes
    • Wang X, Nagl NG, Wilsker D, et al.: Two related ARID family proteins are alternative subunits of human SWI/SNF complexes. Biochem J 2004; 383: 319-325.
    • (2004) Biochem J , vol.383 , pp. 319-325
    • Wang, X.1    Nagl, N.G.2    Wilsker, D.3
  • 35
    • 0037028488 scopus 로고    scopus 로고
    • MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia
    • Ruault M, Brun ME, Ventura M, et al.: MLL3, a new human member of the TRX/MLL gene family, maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia. Gene 2002; 284: 73-81.
    • (2002) Gene , vol.284 , pp. 73-81
    • Ruault, M.1    Brun, M.E.2    Ventura, M.3
  • 36
    • 33749993417 scopus 로고    scopus 로고
    • The consensus coding sequences of human breast and colorectal cancers
    • Sjoblom T, Jones S, Wood LD, et al.: The consensus coding sequences of human breast and colorectal cancers. Science 2006; 314: 268-274.
    • (2006) Science , vol.314 , pp. 268-274
    • Sjoblom, T.1    Jones, S.2    Wood, L.D.3
  • 37
    • 34248547564 scopus 로고    scopus 로고
    • Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma
    • Balakrishnan A, Bleeker FE, Lamba S, et al.: Novel somatic and germline mutations in cancer candidate genes in glioblastoma, melanoma, and pancreatic carcinoma. Cancer Res 2007; 67: 3545-3550.
    • (2007) Cancer Res , vol.67 , pp. 3545-3550
    • Balakrishnan, A.1    Bleeker, F.E.2    Lamba, S.3
  • 38
    • 84859947197 scopus 로고    scopus 로고
    • Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma
    • Mann KM, Ward JM, Yew CC, et al.: Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma. Proc Natl Acad Sci USA 2012; 109: 5934-5941.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 5934-5941
    • Mann, K.M.1    Ward, J.M.2    Yew, C.C.3
  • 39
    • 0028597442 scopus 로고
    • Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: An investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients
    • Sessa F, Solcia E, Capella C, et al.: Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: An investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch 1994; 425: 357-367.
    • (1994) Virchows Arch , vol.425 , pp. 357-367
    • Sessa, F.1    Solcia, E.2    Capella, C.3
  • 40
    • 79958807263 scopus 로고    scopus 로고
    • Molecular signatures of pancreatic cancer
    • Hong SM, Park JY, Hruban RH, et al.: Molecular signatures of pancreatic cancer. Arch Pathol Lab Med 2011; 135: 716-727.
    • (2011) Arch Pathol Lab Med , vol.135 , pp. 716-727
    • Hong, S.M.1    Park, J.Y.2    Hruban, R.H.3
  • 41
    • 81355160555 scopus 로고    scopus 로고
    • Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas
    • Yamaguchi H, Kuboki Y, Hatori T, et al.: Somatic mutations in PIK3CA and activation of AKT in intraductal tubulopapillary neoplasms of the pancreas. Am J Surg Pathol 2011; 35: 1812-1817.
    • (2011) Am J Surg Pathol , vol.35 , pp. 1812-1817
    • Yamaguchi, H.1    Kuboki, Y.2    Hatori, T.3
  • 42
    • 33947403142 scopus 로고    scopus 로고
    • BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas
    • Schonleben F, Qiu W, Bruckman KC, et al.: BRAF and KRAS gene mutations in intraductal papillary mucinous neoplasm/carcinoma (IPMN/IPMC) of the pancreas. Cancer Lett 2007; 249: 242-248.
    • (2007) Cancer Lett , vol.249 , pp. 242-248
    • Schonleben, F.1    Qiu, W.2    Bruckman, K.C.3
  • 43
    • 0034495006 scopus 로고    scopus 로고
    • Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: Comparison with conventional ductal adenocarcinomas
    • Iacobuzio-Donahue CA, Klimstra DS, Adsay NV, et al.: Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: Comparison with conventional ductal adenocarcinomas. Am J Pathol 2000; 157: 755-761.
    • (2000) Am J Pathol , vol.157 , pp. 755-761
    • Iacobuzio-Donahue, C.A.1    Klimstra, D.S.2    Adsay, N.V.3
  • 44
    • 0038107613 scopus 로고    scopus 로고
    • Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms
    • Sahin F, Maitra A, Argani P, et al.: Loss of Stk11/Lkb1 expression in pancreatic and biliary neoplasms. Mod Pathol 2003; 16: 686-691.
    • (2003) Mod Pathol , vol.16 , pp. 686-691
    • Sahin, F.1    Maitra, A.2    Argani, P.3
  • 45
    • 67650898228 scopus 로고    scopus 로고
    • LKB1 and AMPK family signaling: The intimate link between cell polarity and energy metabolism
    • Jansen M, Ten Klooster JP, Offerhaus GJ, et al.: LKB1 and AMPK family signaling: The intimate link between cell polarity and energy metabolism. Physiol Rev 2009; 89: 777-798.
    • (2009) Physiol Rev , vol.89 , pp. 777-798
    • Jansen, M.1    Ten Klooster, J.P.2    Offerhaus, G.J.3
  • 46
    • 0032984141 scopus 로고    scopus 로고
    • Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers
    • Su GH, Hruban RH, Bansal RK, et al.: Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers. Am J Pathol 1999; 154: 1835-1840.
    • (1999) Am J Pathol , vol.154 , pp. 1835-1840
    • Su, G.H.1    Hruban, R.H.2    Bansal, R.K.3
  • 47
    • 2942527434 scopus 로고    scopus 로고
    • Relative frequency and morphology of cancers in STK11 mutation carriers
    • Lim W, Olschwang S, Keller JJ, et al.: Relative frequency and morphology of cancers in STK11 mutation carriers. Gastroenterology 2004; 126: 1788-1794.
    • (2004) Gastroenterology , vol.126 , pp. 1788-1794
    • Lim, W.1    Olschwang, S.2    Keller, J.J.3
  • 48
    • 0034464147 scopus 로고    scopus 로고
    • Very high risk of cancer in familial Peutz-Jeghers syndrome
    • Giardiello FM, Brensinger JD, Tersmette AC, et al.: Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 2000; 119: 1447-1453.
    • (2000) Gastroenterology , vol.119 , pp. 1447-1453
    • Giardiello, F.M.1    Brensinger, J.D.2    Tersmette, A.C.3
  • 49
    • 0032955877 scopus 로고    scopus 로고
    • Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: A clinicopathologic study of 130 cases
    • Thompson LD, Becker RC, Przygodzki RM, et al.: Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: A clinicopathologic study of 130 cases. Am J Surg Pathol 1999; 23: 1-16.
    • (1999) Am J Surg Pathol , vol.23 , pp. 1-16
    • Thompson, L.D.1    Becker, R.C.2    Przygodzki, R.M.3
  • 50
    • 49849103219 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasm-When to resect
    • Waters JA, Schmidt CM:, Intraductal papillary mucinous neoplasm-When to resect ? Adv Surg 2008; 42: 87-108.
    • (2008) Adv Surg , vol.42 , pp. 87-108
    • Waters, J.A.1    Schmidt, C.2
  • 51
    • 62249126574 scopus 로고    scopus 로고
    • Pancreatic cysts: Pathologic classification, differential diagnosis, and clinical implications
    • Basturk O, Coban I, Adsay NV:, Pancreatic cysts: Pathologic classification, differential diagnosis, and clinical implications. Arch Pathol Lab Med 2009; 133: 423-438.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 423-438
    • Basturk, O.1    Coban, I.2    Adsay, N.3
  • 52
    • 84859757956 scopus 로고    scopus 로고
    • Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas
    • Furukawa T, Kuboki Y, Tanji E, et al.: Whole-exome sequencing uncovers frequent GNAS mutations in intraductal papillary mucinous neoplasms of the pancreas. Sci Rep 2011; 1: 161.
    • (2011) Sci Rep , vol.1 , pp. 161
    • Furukawa, T.1    Kuboki, Y.2    Tanji, E.3
  • 53
    • 84862907854 scopus 로고    scopus 로고
    • Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways
    • Wu J, Jiao Y, Dal Molin M, et al.: Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Proc Natl Acad Sci USA 2011; 108: 21188-21193.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. 21188-21193
    • Wu, J.1    Jiao, Y.2    Dal Molin, M.3
  • 54
    • 40949118454 scopus 로고    scopus 로고
    • A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95
    • Sugiura T, Yamaguchi A, Miyamoto K:, A cancer-associated RING finger protein, RNF43, is a ubiquitin ligase that interacts with a nuclear protein, HAP95. Exp Cell Res 2008; 314: 1519-1528.
    • (2008) Exp Cell Res , vol.314 , pp. 1519-1528
    • Sugiura, T.1    Yamaguchi, A.2    Miyamoto, K.3
  • 55
    • 0033770179 scopus 로고    scopus 로고
    • Pancreatic involvement in von Hippel-Lindau disease. The Groupe Francophone d'Etude de la Maladie de von Hippel-Lindau
    • Hammel PR, Vilgrain V, Terris B, et al.: Pancreatic involvement in von Hippel-Lindau disease. The Groupe Francophone d'Etude de la Maladie de von Hippel-Lindau. Gastroenterology 2000; 119: 1087-1095.
    • (2000) Gastroenterology , vol.119 , pp. 1087-1095
    • Hammel, P.R.1    Vilgrain, V.2    Terris, B.3
  • 57
    • 73949093736 scopus 로고    scopus 로고
    • Regulation of Wnt/beta-catenin signaling by protein kinases
    • Verheyen EM, Gottardi CJ:, Regulation of Wnt/beta-catenin signaling by protein kinases. Dev Dyn 2010; 239: 34-44.
    • (2010) Dev Dyn , vol.239 , pp. 34-44
    • Verheyen, E.M.1    Gottardi, C.2
  • 58
    • 0030949463 scopus 로고    scopus 로고
    • Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC
    • Morin PJ, Sparks AB, Korinek V, et al.: Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC. Science 1997; 275: 1787-1790.
    • (1997) Science , vol.275 , pp. 1787-1790
    • Morin, P.J.1    Sparks, A.B.2    Korinek, V.3
  • 59
    • 45149125827 scopus 로고    scopus 로고
    • Cystic lesions of the pancreas. A diagnostic and management dilemma
    • Garcea G, Ong SL, Rajesh A, et al.: Cystic lesions of the pancreas. A diagnostic and management dilemma. Pancreatology 2008; 8: 236-251.
    • (2008) Pancreatology , vol.8 , pp. 236-251
    • Garcea, G.1    Ong, S.L.2    Rajesh, A.3
  • 60
    • 78651090526 scopus 로고    scopus 로고
    • Controversies in the management of pancreatic IPMN
    • Tanaka M:, Controversies in the management of pancreatic IPMN. Nat Rev Gastroenterol Hepatol 2011; 8: 56-60.
    • (2011) Nat Rev Gastroenterol Hepatol , vol.8 , pp. 56-60
    • Tanaka, M.1
  • 61
    • 34548669129 scopus 로고    scopus 로고
    • The management of cystic lesions of the pancreas
    • Allen PJ, Brennan MF:, The management of cystic lesions of the pancreas. Adv Surg 2007; 41: 211-228.
    • (2007) Adv Surg , vol.41 , pp. 211-228
    • Allen, P.J.1    Brennan, M.2
  • 62
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida S, Jones S, Bozic I, et al.: Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010; 467: 1114-1117.
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.