The reduction of NADH - Ubiquinone oxidoreductase 24- and 75-kDa subunits in brains of patients with Down syndrome and Alzheimer's disease

Life Sciences

Volumn 68, Issue 24, 2001, Pages 2741-2750

  Kim, Seong Hwan ^a   Vlkolinsky, Roman ^a   Cairns, Nigel ^b   Fountoulakis, Michael ^c   Lubec, Gert ^a  

^a UNIVERSITY OF VIENNA   (Austria)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Alzheimer's disease; Down syndrome; NADH: ubiquinone oxidoreductase (complex I); Neuronal cell death

Indexed keywords

ACONITATE HYDRATASE; MATRIX PROTEIN; MITOCHONDRIAL ENZYME; MITROCHONDRIAL MATRIX PROTEIN P1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; APOPTOSIS; ARTICLE; BRAIN REGION; CAUDATE NUCLEUS; CONTROLLED STUDY; DOWN SYNDROME; ENERGY METABOLISM; ENZYME SUBUNIT; HUMAN; HUMAN TISSUE; MASS SPECTROMETRY; NERVE CELL NECROSIS; OCCIPITAL CORTEX; PARIETAL LOBE; TEMPORAL LOBE; THALAMUS; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ADULT; AGED; ALZHEIMER DISEASE; BRAIN; DOWN SYNDROME; ELECTRON TRANSPORT; ELECTRON TRANSPORT COMPLEX I; ENERGY METABOLISM; HUMANS; MIDDLE AGED; MITOCHONDRIA; MOLECULAR WEIGHT; NADH, NADPH OXIDOREDUCTASES; PROTEIN SUBUNITS;

EID: 0035805113     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01074-8     Document Type: Article

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