Spatio-temporal development of axonopathy in canine intervertebral disc disease as a translational large animal model for nonexperimental spinal cord injury

Brain Pathology

Volumn 23, Issue 1, 2013, Pages 82-99

  Bock, Patricia ^a   Spitzbarth, Ingo ^a,b   Haist, Verena ^a   Stein, Veronika M ^a   Tipold, Andrea ^a,b   Puff, Christina ^a   Beineke, Andreas ^a   Baumgärtner, Wolfgang ^a,b  

^a UNIVERSITY OF VETERINARY MEDICINE HANNOVER   (Germany)

^b CENTER FOR SYSTEMS NEUROSCIENCE   (Germany)

Author keywords

amyloid precursor protein; dog; growth associated protein 43; intervertebral disc disease; spinal cord slice culture; ultrastructure

Indexed keywords

AMYLOID PRECURSOR PROTEIN; GELATINASE A; GELATINASE B; MYELIN BASIC PROTEIN; NEUROFILAMENT PROTEIN; NEUROMODULIN;

AMPLICON; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONTUSION; DISEASE MODEL; DOG; FEMALE; GRANULOCYTE; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTERVERTEBRAL DISK DEGENERATION; INTERVERTEBRAL DISK HERNIA; MACROPHAGE; MALE; NEUROPATHY; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SPINAL CORD INJURY; TISSUE STRUCTURE; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; AXONS; DISEASE MODELS, ANIMAL; DOGS; FEMALE; GAP-43 PROTEIN; GENE EXPRESSION REGULATION; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INTERVERTEBRAL DISC DEGENERATION; INTERVERTEBRAL DISC DISPLACEMENT; MACROPHAGES; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICROGLIA; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, IMMUNOELECTRON; MYELIN BASIC PROTEIN; NEUROFILAMENT PROTEINS; ORGAN CULTURE TECHNIQUES; PEPTIDE ELONGATION FACTOR 1; PHAGOCYTES; RNA, MESSENGER; SPINAL CORD; SPINAL CORD INJURIES; STATISTICS, NONPARAMETRIC;

EID: 84870933807     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/j.1750-3639.2012.00617.x     Document Type: Article

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