Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis

Genes and Immunity

Volumn 6, Issue 8, 2005, Pages 720-722

  Seldin, M F ^a   Shigeta, R ^a   Laiho, K ^b   Li, H ^a   Saila, H ^b   Savolainen, A ^b   Leirisalo Repo, M ^c   Aho, K ^d   Tuomilehto Wolf, E ^d   Kaarela, K ^b   Kauppi, M ^b   Alexander, H C ^e   Begovich, A B ^e   Tuomilehto, J ^d,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b RHEUMATISM FOUNDATION HOSPITAL   (Finland)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^e CELERA   (United States)

^f SOUTH OSTROBOTHNIA CENTRAL HOSPITAL   (Finland)

Author keywords

Juvenile idiopathic arthritis; PTPN 22; Rheumatoid arthritis

Indexed keywords

AMINO ACID; RHEUMATOID FACTOR;

ALLELE; ARTICLE; CASE CONTROL STUDY; COHORT ANALYSIS; CONTROLLED STUDY; FAMILY STUDY; FINLAND; GENE; GENE FREQUENCY; GENETIC LINKAGE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HOMOZYGOTE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MAJOR CLINICAL STUDY; POPULATION GENETICS; PRIORITY JOURNAL; PTPN22 GENE; PTPN22 R620W GENE; RHEUMATOID ARTHRITIS; RISK FACTOR;

ALLELES; ARTHRITIS, JUVENILE RHEUMATOID; ARTHRITIS, RHEUMATOID; CASE-CONTROL STUDIES; COHORT STUDIES; CONFIDENCE INTERVALS; FINLAND; GENE FREQUENCY; GENETICS, POPULATION; NUCLEAR FAMILY; ODDS RATIO; POLYMORPHISM, GENETIC; PROTEIN-TYROSINE-PHOSPHATASE; RISK FACTORS; VARIATION (GENETICS);

EID: 28544444239     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/sj.gene.6364255     Document Type: Article

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