A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease

International Journal of Immunogenetics

Volumn 32, Issue 5, 2005, Pages 323-324

  Wagenleiter, S E N ^a   Klein, W ^a   Griga, T ^b   Schmiegel, W ^c   Epplen, Joerg T ^a   Jagiello, P ^a  

^a RUHR UNIVERSITY BOCHUM   (Germany)

^b Knappschaftskrankenhaus ^*  (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; TYROSINE DERIVATIVE; TYROSINE PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; AUTOIMMUNE DISEASE; CONTROLLED STUDY; CROHN DISEASE; DNA POLYMORPHISM; GENETIC PREDISPOSITION; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AMINO ACID SUBSTITUTION; CASE-CONTROL STUDIES; CROHN DISEASE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; PREDICTIVE VALUE OF TESTS; PROTEIN-TYROSINE-PHOSPHATASE;

EID: 25844509213     PISSN: 17443121     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2005.00534.x     Document Type: Article

References (15)

1. Begovich, A.B., Caillier, S.J., Alexander, H.C., Penko, J.M., Hauser, S.L., Barcellos, L.E & Oksenberg, J.R. (2005) The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis. American Journal of Human Genetics, 76, 184.
2. Criswell, L.A., Pfeiffer, K.A., Lum, R.F., Gonzales, B., Novitzke, J., Kern, M. et al. (2005) Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection: the PTPN22 620W allele associates with multiple autoimmune phenotypes. American Journal of Human Genetics, 76, 561.
3. Epplen, C., Jackel, S., Santos, E.J., D'Souza, M., Poehlau, D., Dotzauer, B. et al. (1997) Genetic predisposition to multiple sclerosis as revealed by immunoprinting. Annals of Neurology, 41, 341.
4. Erdfelder, E., Faul, F. & Buchner, A. (1996) GPOWER: a general power analysis program. Behavioral Research Methods, Instruments & Computers, 28, 1.
5. Hasegawa, K., Martin, F., Huang, G., Tumas, D., Diehl, L. & Chan, A.C. (2004) PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells. Science, 303, 685.
6. Hugot, J.P., Chamaillard, M., Zouali, H., Lesage, S., Cezard, J.P., Belaiche, J. et al. (2001) Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature, 411, 599.
7. Hugot, J.P. & Thomas, G. (1998) Genome-wide scanning in inflammatory bowel diseases. Digestive Diseases, 16, 364.
8. Joosens, S., Vermeire, S., Van Steen, K., Godefridis, G., Claessens, G., Pierik, M., Vlietinck, R., Aerts, R., Rutgeerts, P. & Bossuyt, X. (2004) Pancreatic autoantibodies in inflammatory bowel disease. Inflammatory Bowel Disease, 1, 771.
9. Klein, W., Tromm, A., Griga, T., Fricke, H., Folwaczny, C., Hocke, M., Eitner, K., Marx, M., Duerig, N. & Epplen, J.T. (2002) A polymorphism in the CD14 gene is associated with Crohn disease. Scandinavian Journal of Gastroenterology, 37,189.
10. Klein, W., Tromm, A., Griga, T., Fricke, H., Folwaczny, C., Hocke, M., Eitner, K., Marx, M., Runte, M. & Epplen, J.T. (2000) The IL-10 gene is not involved in the predisposition to inflammatory bowel disease. Electrophoresis, 21, 3578.
11. Lee, A.T., Li, W., Liew, A., Bombardier, C., Weisman, M., Massarotti, E.M., Kent, J., Wolfe, E, Begovich, A.B. & Gregersen, P.K. (2005) The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status. Genes Immunity, 6, 129.
12. Lennard-Jones, J.E. (1989) Classification of inflammatory bowel disease. Scandinavian Journal of Gastroenterology, Suppl, 170, 2; discussion 16.
13. Mustelin, T., Alonso, A., Bottini, N., Huynh, H., Rahmouni, S., Nika, K. et al. (2004) Protein tyrosine phosphatases in T cell physiology. Molecular Immunology, 41, 687.
14. Onengut-Gumuscu, S., Ewens, K.G., Spielman, R.S. & Concannon, P. (2004) A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families. Genes Immunity, 5, 678.
15. Russel, M.G., Pastoor, C.J., Janssen, K.M., van Deursen, C.T., Muris, J.W., van Wijlick, E.H. & Stockbrugger, R.W. (1997) Familial aggregation of inflammatory bowel disease: a population-based study in South Limburg, the Netherlands. The South Limburg IBD Study Group. Scandinavian Journal of Gastroenterology, Suppl, 223, 88.