Association of the PTPN22 C1858T single-nucleotide polymorphism with rheumatoid arthritis phenotypes in an inception cohort

Arthritis and Rheumatism

Volumn 52, Issue 9, 2005, Pages 2948-2950

  Wesoly, J ^a   Van Der Helm Van Mil, A H M ^a   Toes, R E ^a   Chokkalingam, A P ^b   Carlton, V E H ^b   Begovich, A B ^b   Huizinga, T W J ^a  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CELERA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; AUTOANTIBODY; CYCLIC CITRULLINATED PEPTIDE ANTIBODY; EPITOPE; HLA DR ANTIGEN; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; RHEUMATOID FACTOR; TRYPTOPHAN;

ALLELE; AMINO ACID SUBSTITUTION; ANTIBODY TITER; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE COURSE; FOOT RADIOGRAPHY; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HAND RADIOGRAPHY; HETEROZYGOTE; HOMOZYGOTE; HUMAN; JOINT DESTRUCTION; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MISSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; REMISSION; RHEUMATOID ARTHRITIS; SINGLE NUCLEOTIDE POLYMORPHISM;

ARTHRITIS, RHEUMATOID; ARTHROGRAPHY; COHORT STUDIES; EARLY DIAGNOSIS; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; JOINTS; MUTATION, MISSENSE; NETHERLANDS; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-TYROSINE-PHOSPHATASE; SEVERITY OF ILLNESS INDEX;

EID: 25444455578     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/art.21294     Document Type: Article

References (9)

1. Begovich AB, Carlton VE, Honigberg LA, Schrodi SJ, Chokkalingam AP, Alexander HC, et al. A missense single-nucleotide polymorphism in a gene encoding a protein tryosine phosphatase (PTPN22) is associated with rheumatoid arthritis. Am J Hum Genet 2004;75:330-7.
2. Gregersen P. Pathways to gene identification in rheumatoid arthritis: PTPN22 and beyond. Immunol Rev 2005;204:74-86.
3. Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, et al. A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004;36:337-8.
4. Van Aken J, van Bilsen JH, Allaart CF, Huizinga TW, Breedveld FC. The Leiden Early Arthritis Clinic. Clin Exp Rheumatol 2003;21:8100-5.
5. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-24.
6. Van der Meer FJ, Koster T, Vandenbroucke JP, Briet E, Rosendaal FR. The Leiden Thrombophilia Study (LETS). Thromb Haemost 1997;78:631-5.
7. Verduyn W, Doxiadis II, Anholts J, Drabbels JJ, Naipal A, D'Amaro J, et al. Biotinylated DRB sequence-specific oligonucleotides: comparison to serologic HLA-DR typing of organ donors in eurotransplant. Hum Immunol 1993;37:59-67.
8. Van der Helm-van Mil AH, Dieude P, Schonkeren JJ, Cornelis F, Huizinga TW. No association between tumour necrosis factor receptor type 2 gene polymorphism and rheumatoid arthritis severity: a comparison of the extremes of phenotypes. Rheumatology (Oxford) 2004;43:1232-4.
9. Van der Heijde DM. Plain x-rays in rheumatoid arthritis: overview of scoring methods, their reliability and applicability. Baillieres Clin Rheumatol 1996;10:435-53.