Atherosclerosis and PTPN22: A study in coronary artery disease

Cardiology

Volumn 119, Issue 1, 2011, Pages 54-56

  Saccucci, P ^a   Banci, M ^b   Cozzoli, E ^a   Neri, A ^a   Magrini, A ^a   Bottini, E ^a   Gloria Bottini, F ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b Valmontone Hospital   (Italy)

Author keywords

Atherosclerosis; Coronary artery disease; PTPN22

Indexed keywords

DNA; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE N22; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DNA DETERMINATION; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HUMAN TISSUE; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; FEMALE; HUMANS; MALE; MIDDLE AGED; PHENOTYPE; POLYMORPHISM, GENETIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 22;

EID: 80051579391     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000329919     Document Type: Article

References (15)

1. Pertovaara M, Raitala A, Juonala M, Kahonen M, Lehtimaki T, Viikari JSA, Raitaka ri OT, Hurme M: Autoimmunity and atherosclerosis: Functional polymorphism of PTPN22 is associated with phenotypes related to the risk of atherosclerosis. The Cardiovascular Risk in Young Finns Study. Clin Exp Immunol 2006; 147: 265-269.
2. Bottini N, Musumeci L, Alonso A, Rahmouni S, Nika K, Rostamkhani M, MacMurray J, Meloni GF, Lucarelli P, Pellecchia M, Eisenbarth GS, Comings D, Mustelin T: A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes. Nat Genet 2004; 36: 337-338.
3. Vang T, Congia M, Macis MD, Musumeci L, Orrú V, Zavattari P, Nika K, Tautz L, Taskén K, Cucca F, Mustelin T, Bottini N: Autoimmune- associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat Genet 2005; 37: 1317-1319.
4. Statistical Package for the Social Sciences, SPSS/PC+ Version 5.0. Chicago, SPSS, 1992.
5. Sokal J, Rohlf F: Biometry. New York, Freeman, 1981.
6. Banci M, Saccucci P, D'Annibale F, Dofcaci A, Trionfera G, Magrini A, Bottini N, Bottini E, Gloria-Bottini F: ACP1 genetic polymorphism and coronary artery disease: An association study. Cardiology 2009; 113: 236-242.
7. Safranow K, Rzeuski R, Binczak-Kuleta A, Czyzycka E, Skowronek J, Jakubowska K, Wojtarowicz A, Loniewska B, Ciechanowicz A, Kornacewicz-Jach Z, Chlubek D: ADA *2 allele of the adenosine deaminase gene may protect against coronary artery disease. Cardiology 2007; 108: 275-281.
8. Banci M, Saccucci P, D'Annibale F, Dofcaci A, Trionfera G, Magrini A, Bottini N, Bottini E, Gloria-Bottini F: Adenosine deaminase genetic polymorphism and coronary artery disease. Cardiology 2009; 112: 74-75.
9. Orozco G, Sánchez E, González-Gay MA, López-Nevot MA, Torres B, Cáliz R, Ortego- Centeno N, Jiménez-Alonso J, Pascual-Salcedo D, Balsa A, de Pablo R, Nuñez-Roldan A, González-Escribano MF, Martín J: Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 2005; 52: 219-224.
10. Palomino-Morales R, Gonzalez-Juanatey C, Vazquez-Rodriguez TR, Rodriguez L, Miranda- Filloy JA, Pascual-Salcedo D, Balsa A, Fernandez-Gutierrez B, Llorca J, Martin J, Gonzalez-Gay MA: Lack of association of PTPN22, STAT4 and TRAF1/C5 gene polymorphisms with cardiovascular risk in rheumatoid arthritis. Clin Exp Rheumatol 2010; 28: 695-701.
11. Bottini N, Bottini E, Gloria-Bottini F, Mustelin T: Low-molecular-weight protein tyrosine phosphatase and human disease: In search of biochemical mechanisms. Arch Immunol Ther Exp 2002; 50: 95-104.
12. Bottini N, Stefanini L, Williams S, Alonso A, Jascur T, Abraham RT, Couture C, Mustelin T: Activation of ZAP-70 through specific dephosphorylation at the inhibitory Tyr-292 by the low molecular weight phosphotyrosine phosphatase (LMPTP). J Biol Chem 2002; 277: 24220-24224.
13. Hansson GK: Inflammation and immune response in atherosclerosis. Curr Atheroscler Rep 1999; 1: 150-155.
14. Ostos MA, Recalde D, Zakin MM, Scott-Algara D: Implication of natural killer T cells in atherosclerosis development during a LPS-induced chronic inflammation. FEBS Lett 2002; 519: 23-29.
15. Frostegård J: Atherosclerosis in patients with autoimmune disorders. Arterioscler Thromb Vasc Biol 2005; 25: 1776-1785.