-
1
-
-
0037022008
-
Crohn's disease
-
Shanahan F. Crohn's disease. Lancet 2002 : 359 : 62 9.
-
(2002)
Lancet
, vol.359
, pp. 62-9
-
-
Shanahan, F.1
-
2
-
-
3042654973
-
Protein tyrosine phosphatases in T cell physiology
-
DOI 10.1016/j.molimm.2004.04.015, PII S0161589004001324
-
Mustelin T, Alonso A, Bottinit N et al. Protein tyrosine phosphatases in T cell physiology. Mol Immunol 2004 : 41 : 687 700. (Pubitemid 38824623)
-
(2004)
Molecular Immunology
, vol.41
, Issue.6-7
, pp. 687-700
-
-
Mustelin, T.1
Alonso, A.2
Bottini, N.3
Huynh, H.4
Rahmouni, S.5
Nika, K.6
Louis-Dit-Sully, C.7
Tautz, L.8
Togo, S.H.9
Bruckner, S.10
Mena-Duran, A.V.11
Al-Khouri, A.M.12
-
3
-
-
42649105767
-
Protein tyrosine phosphatases in autoimmunity
-
Vang T, Miletic AV, Arimura Y et al. Protein tyrosine phosphatases in autoimmunity. Annu Rev Immunol 2008 : 26 : 29 55.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 29-55
-
-
Vang, T.1
Miletic, A.V.2
Arimura, Y.3
-
4
-
-
34347341846
-
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
-
Todd JA, Walker NM, Cooper JD et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007 : 39 : 857 864.
-
(2007)
Nat Genet
, vol.39
, pp. 857-864
-
-
Todd, J.A.1
Walker, N.M.2
Cooper, J.D.3
-
5
-
-
58149091678
-
Shared and distinct genetic variants in type 1 diabetes and celiac disease
-
Smyth DJ, Plagnol V, Walker NM et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 2008 : 359 : 2767 2777.
-
(2008)
N Engl J Med
, vol.359
, pp. 2767-2777
-
-
Smyth, D.J.1
Plagnol, V.2
Walker, N.M.3
-
6
-
-
20144388808
-
The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status
-
Lee AT, Li W, Liew A et al. The PTPN22 R620W polymorphism associates with RF positive rheumatoid arthritis in a dose-dependent manner but not with HLA-SE status. Genes Immun 2005 : 6 : 129 133.
-
(2005)
Genes Immun
, vol.6
, pp. 129-133
-
-
Lee, A.T.1
Li, W.2
Liew, A.3
-
7
-
-
19944433325
-
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
-
Orozco G, Sanchez E, Gonzalez-Gay MA et al. Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus. Arthritis Rheum 2005 : 52 : 219 224.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 219-224
-
-
Orozco, G.1
Sanchez, E.2
Gonzalez-Gay, M.A.3
-
8
-
-
25444507438
-
Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population
-
Zhemakova A, Eerligh P, Wijmenga C et al. Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population. Genes Immun 2005 : 6 : 459 461.
-
(2005)
Genes Immun
, vol.6
, pp. 459-461
-
-
Zhemakova, A.1
Eerligh, P.2
Wijmenga, C.3
-
9
-
-
7044253358
-
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
-
Smyth D, Cooper JD, Collins JE et al. Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus. Diabetes 2004 : 53 : 3020 3023.
-
(2004)
Diabetes
, vol.53
, pp. 3020-3023
-
-
Smyth, D.1
Cooper, J.D.2
Collins, J.E.3
-
10
-
-
29644432112
-
Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population
-
Kahles H, Ramos-Lopez E, Lange B et al. Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population. Eur J Endocrinol 2005 : 153 : 895 899.
-
(2005)
Eur J Endocrinol
, vol.153
, pp. 895-899
-
-
Kahles, H.1
Ramos-Lopez, E.2
Lange, B.3
-
11
-
-
11144266638
-
Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes
-
Ladner MB, Bottini N, Valdes AM, Noble JA. Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes. Hum Immunol 2005 : 66 : 60 64.
-
(2005)
Hum Immunol
, vol.66
, pp. 60-64
-
-
Ladner, M.B.1
Bottini, N.2
Valdes, A.M.3
Noble, J.A.4
-
12
-
-
33646502353
-
The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population
-
Fedetz M, Matesanz F, Caro-Maldonado A et al. The 1858T PTPN22 gene variant contributes to a genetic risk of type 1 diabetes in a Ukrainian population. Tissue Antigens 2006 : 67 : 430 433.
-
(2006)
Tissue Antigens
, vol.67
, pp. 430-433
-
-
Fedetz, M.1
Matesanz, F.2
Caro-Maldonado, A.3
-
13
-
-
4143105691
-
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE
-
Kyogoku C, Langefeld CD, Ortmann WA et al. Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. Am J Hum Genet 2004 : 75 : 504 507.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 504-507
-
-
Kyogoku, C.1
Langefeld, C.D.2
Ortmann, W.A.3
-
14
-
-
33750695297
-
Multiplex family-based study in systemic lupus erythematosus: Association between the R620W polymorphism of PTPN22 and the FcgammaRIIa (CD32A) R131 allele
-
Balada E, Villarreal-Tolchinsky J, Ordi-Ros J et al. Multiplex family-based study in systemic lupus erythematosus: association between the R620W polymorphism of PTPN22 and the FcgammaRIIa (CD32A) R131 allele. Tissue Antigens 2006 : 68 : 432 438.
-
(2006)
Tissue Antigens
, vol.68
, pp. 432-438
-
-
Balada, E.1
Villarreal-Tolchinsky, J.2
Ordi-Ros, J.3
-
15
-
-
33645317378
-
The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis
-
Hinks A, Worthington J, Thomson W. The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford) 2006 : 45 : 365 368.
-
(2006)
Rheumatology (Oxford)
, vol.45
, pp. 365-368
-
-
Hinks, A.1
Worthington, J.2
Thomson, W.3
-
16
-
-
33750218666
-
Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population
-
Ikari K, Momohara S, Inoue E et al. Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population. Rheumatology 2006 : 45 : 1345 1348.
-
(2006)
Rheumatology
, vol.45
, pp. 1345-1348
-
-
Ikari, K.1
Momohara, S.2
Inoue, E.3
-
17
-
-
1942489307
-
T-cell protein tyrosine phosphatase deletion results in progressive systematic inflammatory disease
-
Heinonen KM, Nestel FP, Newell EW et al. T-cell protein tyrosine phosphatase deletion results in progressive systematic inflammatory disease. Blood 2004 : 103 : 3457 3464.
-
(2004)
Blood
, vol.103
, pp. 3457-3464
-
-
Heinonen, K.M.1
Nestel, F.P.2
Newell, E.W.3
-
18
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007 : 447 : 661 678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
19
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
Parkes M, Barrett JC, Prescott NJ et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet 2007 : 39 : 830 832.
-
(2007)
Nat Genet
, vol.39
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
-
20
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet 2008 : 40 : 713 715.
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
-
21
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet 2007 : 39 : 596 603.
-
(2007)
Nat Genet
, vol.39
, pp. 596-603
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
22
-
-
34247579326
-
Novel Crohn's disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S et al. Novel Crohn's disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet 2007 : 3 : 538 543.
-
(2007)
PLoS Genet
, vol.3
, pp. 538-543
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
-
23
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008 : 40 : 955 962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
24
-
-
33749316892
-
High incidence of Crohn's disease in Canterbury, New Zealand: Results of an epidemiologic study
-
Gearry RB, Richardson A, Frampton CM et al. High incidence of Crohn's disease in Canterbury, New Zealand: results of an epidemiologic study. Inflamm Bowel Dis 2006 : 12 : 936 943.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 936-943
-
-
Gearry, R.B.1
Richardson, A.2
Frampton, C.M.3
-
25
-
-
55249127348
-
Paediatric inflammatory bowel disease in New Zealand
-
Yap J, Wesley A, Mouat S et al. Paediatric inflammatory bowel disease in New Zealand. N Z Med J 2008 : 121 : 19 34.
-
(2008)
N Z Med J
, vol.121
, pp. 19-34
-
-
Yap, J.1
Wesley, A.2
Mouat, S.3
-
26
-
-
58149393184
-
Perianal disease predicts changes in Crohn's disease phenotype-results of a population-based study of inflammatory bowel disease phenotype
-
Tarrant KM, Barclay ML, Frampton CM et al. Perianal disease predicts changes in Crohn's disease phenotype-results of a population-based study of inflammatory bowel disease phenotype. Am J Gastroenterol 2008 : 103 : 3082 3093.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 3082-3093
-
-
Tarrant, K.M.1
Barclay, M.L.2
Frampton, C.M.3
-
27
-
-
0024810567
-
Classification of inflammatory bowel disease
-
Lennard-Jones JE. Classification of inflammatory bowel disease. Scand J Gastroenterol 1989 : 170 : 2 6.
-
(1989)
Scand J Gastroenterol
, vol.170
, pp. 2-6
-
-
Lennard-Jones, J.E.1
-
31
-
-
0031466983
-
From genotypes to genes: Doubling the sample size
-
Sasieni PD. From genotypes to genes: doubling the sample size. Biometrics 1997 : 53 : 1253 1261.
-
(1997)
Biometrics
, vol.53
, pp. 1253-1261
-
-
Sasieni, P.D.1
-
32
-
-
0036020892
-
A direct approach to false discovery rates
-
Storey JD. A direct approach to false discovery rates. J R Stat Soc 2002 : 64 : 479 498.
-
(2002)
J R Stat Soc
, vol.64
, pp. 479-498
-
-
Storey, J.D.1
-
33
-
-
0030305457
-
R: A language for data analysis and graphics
-
Ihaka R, Gentleman R. R: A language for data analysis and graphics. J Comput Graph Stat 1996 : 5 : 299 314.
-
(1996)
J Comput Graph Stat
, vol.5
, pp. 299-314
-
-
Ihaka, R.1
Gentleman, R.2
-
34
-
-
0032430986
-
Power and sample size calculations for studies involving linear regression
-
Dupont WD, Plummer WD Jr. Power and sample size calculations for studies involving linear regression. Control Clin Trials 1998 : 19 : 589 601.
-
(1998)
Control Clin Trials
, vol.19
, pp. 589-601
-
-
Dupont, W.D.1
Plummer Jr., W.D.2
-
35
-
-
0023907135
-
Cardiff Crohn's jubilee. The incidence over 50 years
-
Rose JDR, Roberts GM, Williams G et al. Cardiff Crohn's jubilee. The incidence over 50 years. Gut 1988 : 29 : 346 351.
-
(1988)
Gut
, vol.29
, pp. 346-351
-
-
Rose, J.D.R.1
Roberts, G.M.2
Williams, G.3
-
36
-
-
0029810041
-
Crohn's disease: Influence of age at diagnosis on site and clinical type of disease
-
Polito JM, Childs B, Mellits ED et al. Crohn's disease: influence of age at diagnosis on site and clinical type of disease. Gastroenterology 1996 : 111 : 580 586.
-
(1996)
Gastroenterology
, vol.111
, pp. 580-586
-
-
Polito, J.M.1
Childs, B.2
Mellits, E.D.3
-
37
-
-
0036288704
-
In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis
-
Bridger S, Lee JC, Bjarnason I et al. In siblings with similar genetic susceptibility for inflammatory bowel disease, smokers tend to develop Crohn's disease and non-smokers develop ulcerative colitis. Gut 2002 : 51 : 21 5.
-
(2002)
Gut
, vol.51
, pp. 21-5
-
-
Bridger, S.1
Lee, J.C.2
Bjarnason, I.3
-
38
-
-
0023092757
-
Immune and inflammatory function in cigarette smokers
-
Holt PG. Immune and inflammatory function in cigarette smokers. Thorax 1987 : 42 : 241 249.
-
(1987)
Thorax
, vol.42
, pp. 241-249
-
-
Holt, P.G.1
-
39
-
-
0023934530
-
Effects of tobacco glycoprotein (TGP) on the immune system. II. TGP stimulates the proliferation of human T cells and the differentiation of human B cells into Ig secreting cells
-
Francus T, Klein RF, Staiano-Coico L et al. Effects of tobacco glycoprotein (TGP) on the immune system. II. TGP stimulates the proliferation of human T cells and the differentiation of human B cells into Ig secreting cells. J Immunol 1988 : 140 : 1823 1829.
-
(1988)
J Immunol
, vol.140
, pp. 1823-1829
-
-
Francus, T.1
Klein, R.F.2
Staiano-Coico, L.3
-
40
-
-
0031012334
-
Smoking and immunity: An additional player in the mosaic of autoimmunity
-
George J, Levy Y, Shoenfeld Y. Smoking and immunity: an additional player in the mosaic of autoimmunity. Scand J Immunol 1997 : 45 : 1 6.
-
(1997)
Scand J Immunol
, vol.45
, pp. 1-6
-
-
George, J.1
Levy, Y.2
Shoenfeld, Y.3
-
41
-
-
70649104669
-
Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase N2
-
Scharl M, Paul G, Weber A et al. Protection of epithelial barrier function by the Crohn's disease associated gene protein tyrosine phosphatase N2. Gastroenterology 2009 : 137 : 2030 2040.
-
(2009)
Gastroenterology
, vol.137
, pp. 2030-2040
-
-
Scharl, M.1
Paul, G.2
Weber, A.3
-
42
-
-
34249933089
-
Altered permeability in inflammatory bowel disease: Pathophysiology and clinical implications
-
Mankertz J, Schulzke JD. Altered permeability in inflammatory bowel disease: pathophysiology and clinical implications. Curr Opin Gastroenterol 2007 : 23 : 379 383.
-
(2007)
Curr Opin Gastroenterol
, vol.23
, pp. 379-383
-
-
Mankertz, J.1
Schulzke, J.D.2
-
43
-
-
26044482775
-
The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease
-
Martin MC, Oliver J, Urcelay E et al. The functional genetic variation in the PTPN22 gene has a negligible effect on the susceptibility to develop inflammatory bowel disease. Tissue Antigens 2005 : 66 : 314 317.
-
(2005)
Tissue Antigens
, vol.66
, pp. 314-317
-
-
Martin, M.C.1
Oliver, J.2
Urcelay, E.3
-
44
-
-
26044441694
-
A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population
-
Prescott NJ, Fisher SA, Onnie C et al. A general autoimmunity gene (PTPN22) is not associated with inflammatory bowel disease in a British population. Tissue Antigens 2005 : 66 : 318 320.
-
(2005)
Tissue Antigens
, vol.66
, pp. 318-320
-
-
Prescott, N.J.1
Fisher, S.A.2
Onnie, C.3
-
45
-
-
22244442459
-
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations
-
van Oene M, Wintle RF, Liu X et al. Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations. Arthritis Rheum 2005 : 52 : 1993 1998.
-
(2005)
Arthritis Rheum
, vol.52
, pp. 1993-1998
-
-
Van Oene, M.1
Wintle, R.F.2
Liu, X.3
-
46
-
-
25844509213
-
A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease
-
Wagenleiter SE, Klein W, Griga T et al. A case-control study of tyrosine phosphatase (PTPN22) confirms the lack of association with Crohn's disease. Int J Immunogenet 2005 : 32 : 323 324.
-
(2005)
Int J Immunogenet
, vol.32
, pp. 323-324
-
-
Wagenleiter, S.E.1
Klein, W.2
Griga, T.3
|