-
1
-
-
1842579286
-
Genetics of type 1 diabetes
-
vii. 10.1016/S0889-8529(03)00082-3 15053891
-
Pugliese A Genetics of type 1 diabetes Endocrinol Metab Clin North Am 2004, 33(1):1-16, vii. 10.1016/S0889-8529(03)00082-3 15053891
-
(2004)
Endocrinol Metab Clin North Am
, vol.33
, Issue.1
, pp. 1-16
-
-
Pugliese, A.1
-
2
-
-
12144291502
-
A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes
-
Epub 2004 Mar 7. 10.1038/ng1323 15004560
-
Bottini N Musumeci L Alonso A Rahmouni S Nika K Rostamkhani M MacMurray J Meloni GF Lucarelli P Pellecchia M Eisenbarth GS Comings D Mustelin T A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes Nat Genet 2004, 36(4):337-8. Epub 2004 Mar 7. 10.1038/ ng1323 15004560
-
(2004)
Nat Genet
, vol.36
, Issue.4
, pp. 337-338
-
-
Bottini, N.1
Musumeci, L.2
Alonso, A.3
Rahmouni, S.4
Nika, K.5
Rostamkhani, M.6
MacMurray, J.7
Meloni, G.F.8
Lucarelli, P.9
Pellecchia, M.10
Eisenbarth, G.S.11
Comings, D.12
Mustelin, T.13
-
3
-
-
3242713277
-
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis
-
Epub 2004 Jun 18. 1216068 15208781 10.1086/422827
-
Begovich AB Carlton VE Honigberg LA Schrodi SJ Chokkalingam AP Alexander HC Ardlie KG Huang Q Smith AM Spoerke JM Conn MT Chang M Chang SY Saiki RK Catanese JJ Leong DU Garcia VE McAllister LB Jeffery DA Lee AT Batliwalla F Remmers E Criswell LA Seldin MF Kastner DL Amos CI Sninsky JJ Gregersen PK A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritis Am J Hum Genet 2004, 75(2):330-7. Epub 2004 Jun 18. 1216068 15208781 10.1086/422827
-
(2004)
Am J Hum Genet
, vol.75
, Issue.2
, pp. 330-337
-
-
Begovich, A.B.1
Carlton, V.E.2
Honigberg, L.A.3
Schrodi, S.J.4
Chokkalingam, A.P.5
Alexander, H.C.6
Ardlie, K.G.7
Huang, Q.8
Smith, A.M.9
Spoerke, J.M.10
Conn, M.T.11
Chang, M.12
Chang, S.Y.13
Saiki, R.K.14
Catanese, J.J.15
Leong, D.U.16
Garcia, V.E.17
McAllister, L.B.18
Jeffery, D.A.19
Lee, A.T.20
Batliwalla, F.21
Remmers, E.22
Criswell, L.A.23
Seldin, M.F.24
Kastner, D.L.25
Amos, C.I.26
Sninsky, J.J.27
Gregersen, P.K.28
more..
-
4
-
-
19944433325
-
Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus
-
10.1002/art.20771 15641066
-
Orozco G Sanchez E Gonzalez-Gay MA Lopez-Nevot MA Torres B Caliz R Ortego-Centeno N Jimenez-Alonso J Pascual-Salcedo D Balsa A de Pablo R Nunez-Roldan A Gonzalez-Escribano MF Martin J Association of a functional single-nucleotide polymorphism of PTPN22, encoding lymphoid protein phosphatase, with rheumatoid arthritis and systemic lupus erythematosus Arthritis Rheum 2005, 52(1):219-224 10.1002/art.20771 15641066
-
(2005)
Arthritis Rheum
, vol.52
, Issue.1
, pp. 219-224
-
-
Orozco, G.1
Sanchez, E.2
Gonzalez-Gay, M.A.3
Lopez-Nevot, M.A.4
Torres, B.5
Caliz, R.6
Ortego-Centeno, N.7
Jimenez-Alonso, J.8
Pascual-Salcedo, D.9
Balsa, A.10
de Pablo, R.11
Nunez-Roldan, A.12
Gonzalez-Escribano, M.F.13
Martin, J.14
-
5
-
-
22244442459
-
Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations
-
10.1002/art.21123 15986374
-
van Oene M Wintle RF Liu X Yazdanpanah M Gu X Newman B Kwan A Johnson B Owen J Greer W Mosher D Maksymowych W Keystone E Rubin LA Amos CI Siminovitch KA Association of the lymphoid tyrosine phosphatase R620W variant with rheumatoid arthritis, but not Crohn's disease, in Canadian populations Arthritis Rheum 2005, 52(7):1993-1998 10.1002/art.21123 15986374
-
(2005)
Arthritis Rheum
, vol.52
, Issue.7
, pp. 1993-1998
-
-
van Oene, M.1
Wintle, R.F.2
Liu, X.3
Yazdanpanah, M.4
Gu, X.5
Newman, B.6
Kwan, A.7
Johnson, B.8
Owen, J.9
Greer, W.10
Mosher, D.11
Maksymowych, W.12
Keystone, E.13
Rubin, L.A.14
Amos, C.I.15
Siminovitch, K.A.16
-
6
-
-
22244475440
-
Association of the PTPN22 locus with rheumatoid arthritis in a New Zealand Caucasian cohort
-
10.1002/art.21126 15986352
-
Simkins HM Merriman ME Highton J Chapman PT O'Donnell JL Jones PB Gow PJ McLean L Pokorny V Harrison AA Merriman TR Association of the PTPN22 locus with rheumatoid arthritis in a New Zealand Caucasian cohort Arthritis Rheum 2005, 52(7):2222-2225 10.1002/art.21126 15986352
-
(2005)
Arthritis Rheum
, vol.52
, Issue.7
, pp. 2222-2225
-
-
Simkins, H.M.1
Merriman, M.E.2
Highton, J.3
Chapman, P.T.4
O'Donnell, J.L.5
Jones, P.B.6
Gow, P.J.7
McLean, L.8
Pokorny, V.9
Harrison, A.A.10
Merriman, T.R.11
-
7
-
-
25444483876
-
PTPN22 genetic variation: Evidence for multiple variants associated with rheumatoid arthritis
-
Epub 2005 Aug 10. 1275606 16175503 10.1086/468189
-
Carlton VE Hu X Chokkalingam AP Schrodi SJ Brandon R Alexander HC Chang M Catanese JJ Leong DU Ardlie KG Kastner DL Seldin MF Criswell LA Gregersen PK Beasley E Thomson G Amos CI Begovich AB PTPN22 genetic variation: Evidence for multiple variants associated with rheumatoid arthritis Am J Hum Genet 2005, 77(4):567-81. Epub 2005 Aug 10. 1275606 16175503 10.1086/468189
-
(2005)
Am J Hum Genet
, vol.77
, Issue.4
, pp. 567-581
-
-
Carlton, V.E.1
Hu, X.2
Chokkalingam, A.P.3
Schrodi, S.J.4
Brandon, R.5
Alexander, H.C.6
Chang, M.7
Catanese, J.J.8
Leong, D.U.9
Ardlie, K.G.10
Kastner, D.L.11
Seldin, M.F.12
Criswell, L.A.13
Gregersen, P.K.14
Beasley, E.15
Thomson, G.16
Amos, C.I.17
Begovich, A.B.18
-
8
-
-
29144510502
-
The PTPN22 620W allele is a risk factor for Wegener's granulomatosis
-
10.1002/art.21487 16320352
-
Jagiello P Aries P Arning L Wagenleiter SE Csernok E Hellmich B Gross WL Epplen JT The PTPN22 620W allele is a risk factor for Wegener's granulomatosis Arthritis Rheum 2005, 52(12):4039-4043 10.1002/art.21487 16320352
-
(2005)
Arthritis Rheum
, vol.52
, Issue.12
, pp. 4039-4043
-
-
Jagiello, P.1
Aries, P.2
Arning, L.3
Wagenleiter, S.E.4
Csernok, E.5
Hellmich, B.6
Gross, W.L.7
Epplen, J.T.8
-
9
-
-
32044456473
-
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis
-
10.1002/ana.20751 16437561
-
Vandiedonck C Capdevielle C Giraud M Krumeich S Jais JP Eymard B Tranchant C Gajdos P Garchon HJ Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis Ann Neurol 2006, 59(2):404-407 10.1002/ana.20751 16437561
-
(2006)
Ann Neurol
, vol.59
, Issue.2
, pp. 404-407
-
-
Vandiedonck, C.1
Capdevielle, C.2
Giraud, M.3
Krumeich, S.4
Jais, J.P.5
Eymard, B.6
Tranchant, C.7
Gajdos, P.8
Garchon, H.J.9
-
10
-
-
11144292728
-
The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis
-
1196423 15580548 10.1086/427244
-
Begovich AB Caillier SJ Alexander HC Penko JM Hauser SL Barcellos LF Oksenberg JR The R620W polymorphism of the protein tyrosine phosphatase PTPN22 is not associated with multiple sclerosis Am J Hum Genet 2005, 76(1):184-187 1196423 15580548 10.1086/427244
-
(2005)
Am J Hum Genet
, vol.76
, Issue.1
, pp. 184-187
-
-
Begovich, A.B.1
Caillier, S.J.2
Alexander, H.C.3
Penko, J.M.4
Hauser, S.L.5
Barcellos, L.F.6
Oksenberg, J.R.7
-
11
-
-
23844554578
-
C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition
-
10.1016/j.humimm.2005.04.008 16112033
-
Rueda B Nunez C Orozco G Lopez-Nevot MA de la Concha EG Martin J Urcelay E C1858T functional variant of PTPN22 gene is not associated with celiac disease genetic predisposition Hum Immunol 2005, 66(7):848-852 10.1016/ j.humimm.2005.04.008 16112033
-
(2005)
Hum Immunol
, vol.66
, Issue.7
, pp. 848-852
-
-
Rueda, B.1
Nunez, C.2
Orozco, G.3
Lopez-Nevot, M.A.4
de la Concha, E.G.5
Martin, J.6
Urcelay, E.7
-
12
-
-
7044253358
-
Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus
-
10.2337/diabetes.53.11.3020 15504986
-
Smyth D Cooper JD Collins JE Heward JM Franklyn JA Howson JM Vella A Nutland S Rance HE Maier L Barratt BJ Guja C Ionescu-Tirgoviste C Savage DA Dunger DB Widmer B Strachan DP Ring SM Walker N Clayton DG Twells RC Gough SC Todd JA Replication of an association between the lymphoid tyrosine phosphatase locus (LYP/PTPN22) with type 1 diabetes, and evidence for its role as a general autoimmunity locus Diabetes 2004, 53(11):3020-3023 10.2337/diabetes.53.11.3020 15504986
-
(2004)
Diabetes
, vol.53
, Issue.11
, pp. 3020-3023
-
-
Smyth, D.1
Cooper, J.D.2
Collins, J.E.3
Heward, J.M.4
Franklyn, J.A.5
Howson, J.M.6
Vella, A.7
Nutland, S.8
Rance, H.E.9
Maier, L.10
Barratt, B.J.11
Guja, C.12
Ionescu-Tirgoviste, C.13
Savage, D.A.14
Dunger, D.B.15
Widmer, B.16
Strachan, D.P.17
Ring, S.M.18
Walker, N.19
Clayton, D.G.20
Twells, R.C.21
Gough, S.C.22
Todd, J.A.23
more..
-
13
-
-
11044226181
-
A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families
-
10.1038/sj.gene.6364138 15526003
-
Onengut-Gumuscu S Ewens KG Spielman RS Concannon P A functional polymorphism (1858C/T) in the PTPN22 gene is linked and associated with type I diabetes in multiplex families Genes Immun 2004, 5(8):678-680 10.1038/sj.gene.6364138 15526003
-
(2004)
Genes Immun
, vol.5
, Issue.8
, pp. 678-680
-
-
Onengut-Gumuscu, S.1
Ewens, K.G.2
Spielman, R.S.3
Concannon, P.4
-
14
-
-
11144266638
-
Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes
-
10.1016/j.humimm.2004.09.016 15620463
-
Ladner MB Bottini N Valdes AM Noble JA Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetes Hum Immunol 2005, 66(1):60-64 10.1016/j.humimm.2004.09.016 15620463
-
(2005)
Hum Immunol
, vol.66
, Issue.1
, pp. 60-64
-
-
Ladner, M.B.1
Bottini, N.2
Valdes, A.M.3
Noble, J.A.4
-
15
-
-
14644445981
-
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
-
10.2337/diabetes.54.3.906 15734872
-
Zheng W She JX Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes Diabetes 2005, 54(3):906-908 10.2337/diabetes.54.3.906 15734872
-
(2005)
Diabetes
, vol.54
, Issue.3
, pp. 906-908
-
-
Zheng, W.1
She, J.X.2
-
16
-
-
15044345627
-
Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study
-
10.1136/jmg.2004.026971 15744042
-
Qu H Tessier MC Hudson TJ Polychronakos C Confirmation of the association of the R620W polymorphism in the protein tyrosine phosphatase PTPN22 with type 1 diabetes in a family based study J Med Genet 2005, 42(3):266-270 10.1136/jmg.2004.026971 15744042
-
(2005)
J Med Genet
, vol.42
, Issue.3
, pp. 266-270
-
-
Qu, H.1
Tessier, M.C.2
Hudson, T.J.3
Polychronakos, C.4
-
17
-
-
25444507438
-
Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population
-
10.1038/sj.gene.6364220 15875058
-
Zhernakova A Eerligh P Wijmenga C Barrera P Roep BO Koeleman BP Differential association of the PTPN22 coding variant with autoimmune diseases in a Dutch population Genes Immun 2005, 6(6):459-461 10.1038/ sj.gene.6364220 15875058
-
(2005)
Genes Immun
, vol.6
, Issue.6
, pp. 459-461
-
-
Zhernakova, A.1
Eerligh, P.2
Wijmenga, C.3
Barrera, P.4
Roep, B.O.5
Koeleman, B.P.6
-
18
-
-
27844441281
-
PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases
-
10.1038/sj.gene.6364261 16163373
-
Gomez LM Anaya JM Gonzalez CI Pineda-Tamayo R Otero W Arango A Martin J PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases Genes Immun 2005, 6(7):628-631 10.1038/sj.gene.6364261 16163373
-
(2005)
Genes Immun
, vol.6
, Issue.7
, pp. 628-631
-
-
Gomez, L.M.1
Anaya, J.M.2
Gonzalez, C.I.3
Pineda-Tamayo, R.4
Otero, W.5
Arango, A.6
Martin, J.7
-
19
-
-
25844441709
-
Type 1 diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families
-
10.2337/diabetes.54.10.2995 16186404
-
Concannon P Erlich HA Julier C Morahan G Nerup J Pociot F Todd JA Rich SS Type 1 diabetes: Evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families Diabetes 2005, 54(10):2995-3001 10.2337/diabetes.54.10.2995 16186404
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2995-3001
-
-
Concannon, P.1
Erlich, H.A.2
Julier, C.3
Morahan, G.4
Nerup, J.5
Pociot, F.6
Todd, J.A.7
Rich, S.S.8
-
20
-
-
29644432112
-
Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population
-
10.1530/eje.1.02035 16322396
-
Kahles H Ramos-Lopez E Lange B Zwermann O Reincke M Badenhoop K Sex-specific association of PTPN22 1858T with type 1 diabetes but not with Hashimoto's thyroiditis or Addison's disease in the German population Eur J Endocrinol 2005, 153(6):895-899 10.1530/eje.1.02035 16322396
-
(2005)
Eur J Endocrinol
, vol.153
, Issue.6
, pp. 895-899
-
-
Kahles, H.1
Ramos-Lopez, E.2
Lange, B.3
Zwermann, O.4
Reincke, M.5
Badenhoop, K.6
-
21
-
-
70449491816
-
Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: Higher frequency of the risk allele in male compared to female patients
-
1526616 16635271 10.1186/ar1945
-
Pierer M Kaltenhauser S Arnold S Wahle M Baerwald C Hantzschel H Wagner U Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: Higher frequency of the risk allele in male compared to female patients Arthritis Res Ther 2006, 8(3):R75 1526616 16635271 10.1186/ar1945
-
(2006)
Arthritis Res Ther
, vol.8
, Issue.3
-
-
Pierer, M.1
Kaltenhauser, S.2
Arnold, S.3
Wahle, M.4
Baerwald, C.5
Hantzschel, H.6
Wagner, U.7
-
22
-
-
33646252483
-
Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis
-
10.1038/sj.jid.5700179 16456530
-
Huffmeier U Reis A Steffens M Lascorz J Bohm B Lohmann J Wendler J Traupe H Kuster W Wienker TF Burkhardt H Male restricted genetic association of variant R620W in PTPN22 with psoriatic arthritis J Invest Dermatol 2006, 126(4):932-935 10.1038/sj.jid.5700179 16456530
-
(2006)
J Invest Dermatol
, vol.126
, Issue.4
, pp. 932-935
-
-
Huffmeier, U.1
Reis, A.2
Steffens, M.3
Lascorz, J.4
Bohm, B.5
Lohmann, J.6
Wendler, J.7
Traupe, H.8
Kuster, W.9
Wienker, T.F.10
Burkhardt, H.11
-
23
-
-
25444527745
-
Type 1 diabetes in the Spanish population: Additional factors to class II HLA-DR3 and -DR4
-
1097726 15842729 10.1186/1471-2164-6-56
-
Urcelay E Santiago JL de la Calle H Martinez A Mendez J Ibarra JM Maluenda C Fernandez-Arquero M de la Concha EG Type 1 diabetes in the Spanish population: Additional factors to class II HLA-DR3 and -DR4 BMC Genomics 2005, 6(1):56 1097726 15842729 10.1186/1471-2164-6-56
-
(2005)
BMC Genomics
, vol.6
, Issue.1
, pp. 56
-
-
Urcelay, E.1
Santiago, J.L.2
de la Calle, H.3
Martinez, A.4
Mendez, J.5
Ibarra, J.M.6
Maluenda, C.7
Fernandez-Arquero, M.8
de la Concha, E.G.9
-
24
-
-
33750142569
-
Association of the PTPN22/LYP gene with type 1 diabetes
-
10.1111/j.1399-5448.2006.00202.x 17054449
-
Steck AK Liu SY McFann K Barriga KJ Babu SR Eisenbarth GS Rewers MJ She JX Association of the PTPN22/LYP gene with type 1 diabetes Pediatr Diabetes 2006, 7(5):274-278 10.1111/j.1399-5448.2006.00202.x 17054449
-
(2006)
Pediatr Diabetes
, vol.7
, Issue.5
, pp. 274-278
-
-
Steck, A.K.1
Liu, S.Y.2
McFann, K.3
Barriga, K.J.4
Babu, S.R.5
Eisenbarth, G.S.6
Rewers, M.J.7
She, J.X.8
-
25
-
-
33646524724
-
Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes
-
10.1007/s00125-006-0225-4 16614815
-
Hermann R Lipponen K Kiviniemi M Kakko T Veijola R Simell O Knip M Ilonen J Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes Diabetologia 2006, 49(6):1198-1208 10.1007/s00125-006-0225-4 16614815
-
(2006)
Diabetologia
, vol.49
, Issue.6
, pp. 1198-1208
-
-
Hermann, R.1
Lipponen, K.2
Kiviniemi, M.3
Kakko, T.4
Veijola, R.5
Simell, O.6
Knip, M.7
Ilonen, J.8
-
26
-
-
28444469783
-
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
-
10.1038/ng1673 16273109
-
Vang T Congia M Macis MD Musumeci L Orru V Zavattari P Nika K Tautz L Tasken K Cucca F Mustelin T Bottini N Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant Nat Genet 2005, 37(12):1317-1319 10.1038/ng1673 16273109
-
(2005)
Nat Genet
, vol.37
, Issue.12
, pp. 1317-1319
-
-
Vang, T.1
Congia, M.2
Macis, M.D.3
Musumeci, L.4
Orru, V.5
Zavattari, P.6
Nika, K.7
Tautz, L.8
Tasken, K.9
Cucca, F.10
Mustelin, T.11
Bottini, N.12
-
27
-
-
33745169029
-
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
-
10.1016/j.smim.2006.03.008 16697661
-
Bottini N Vang T Cucca F Mustelin T Role of PTPN22 in type 1 diabetes and other autoimmune diseases Semin Immunol 2006, 18(4):207-213 10.1016/ j.smim.2006.03.008 16697661
-
(2006)
Semin Immunol
, vol.18
, Issue.4
, pp. 207-213
-
-
Bottini, N.1
Vang, T.2
Cucca, F.3
Mustelin, T.4
-
28
-
-
0035554904
-
Sex differences in autoimmune disease
-
10.1038/ni0901-777 11526384
-
Whitacre CC Sex differences in autoimmune disease Nat Immunol 2001, 2(9):777-780 10.1038/ni0901-777 11526384
-
(2001)
Nat Immunol
, vol.2
, Issue.9
, pp. 777-780
-
-
Whitacre, C.C.1
|