-
2
-
-
57349095906
-
The international epidemiology of lung cancer: Geographical distribution and secular trends
-
Youlden DR, Cramb SM, Baade PD. The international epidemiology of lung cancer: geographical distribution and secular trends. J Thorac Oncol. 2008;3(8): 819-831.
-
(2008)
J Thorac Oncol
, vol.3
, Issue.8
, pp. 819-831
-
-
Youlden, D.R.1
Cramb, S.M.2
Baade, P.D.3
-
3
-
-
79251643266
-
Revolution in lung cancer: New challenges for the surgical pathologist
-
Cagle PT, Allen TC, Dacic S, et al. Revolution in lung cancer: new challenges for the surgical pathologist. Arch Pathol Lab Med. 2011;135(1):110- 116.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.1
, pp. 110-116
-
-
Cagle, P.T.1
Allen, T.C.2
Dacic, S.3
-
4
-
-
79952981004
-
Lung cancer and the future of pathology
-
Cagle PT, Dacic S. Lung cancer and the future of pathology. Arch Pathol Lab Med. 2011;135(3):293-295.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.3
, pp. 293-295
-
-
Cagle, P.T.1
Dacic, S.2
-
5
-
-
80455177279
-
Current management of small cell lung cancer
-
Neal JW, Gubens MA, Wakelee HA. Current management of small cell lung cancer. Clin Chest Med. 2011;32(4):853-863.
-
(2011)
Clin Chest Med
, vol.32
, Issue.4
, pp. 853-863
-
-
Neal, J.W.1
Gubens, M.A.2
Wakelee, H.A.3
-
7
-
-
84865417560
-
Recent advances in non-small cell lung cancer biology and clinical management
-
Saintigny P, Burger JA. Recent advances in non-small cell lung cancer biology and clinical management. Discov Med. 2012;13(71):287-297.
-
(2012)
Discov Med
, vol.13
, Issue.71
, pp. 287-297
-
-
Saintigny, P.1
Burger, J.A.2
-
8
-
-
79551563284
-
International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma
-
Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society international multidisciplinary classification of lung adenocarcinoma. J Thorac Oncol. 2011;6(2):244-285.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.2
, pp. 244-285
-
-
Travis, W.D.1
Brambilla, E.2
Noguchi, M.3
-
9
-
-
34548457234
-
The IASLC lung cancer staging project: Proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours
-
Goldstraw P, Crowley J, Chansky K, et al. The IASLC lung cancer staging project: proposals for the revision of the TNM stage groupings in the forthcoming (seventh) edition of the TNM classification of malignant tumours. J Thorac Oncol. 2007;2(8):706-714.
-
(2007)
J Thorac Oncol
, vol.2
, Issue.8
, pp. 706-714
-
-
Goldstraw, P.1
Crowley, J.2
Chansky, K.3
-
10
-
-
74949133978
-
American society of clinical oncology clinical practice guideline update on chemotherapy for stage IV nonsmall- cell lung cancer
-
Azzoli CG, Baker S Jr, Temin S, et al. American Society of Clinical Oncology clinical practice guideline update on chemotherapy for stage IV nonsmall- cell lung cancer. J Clin Oncol. 2009;27(36):6251-6266.
-
(2009)
J Clin Oncol
, vol.27
, Issue.36
, pp. 6251-6266
-
-
Azzoli, C.G.1
Baker Jr., S.2
Temin, S.3
-
11
-
-
80053639884
-
2011 focused update of 2009 american society of clinical oncology clinical practice guideline update on chemotherapy for stage iv non-small-cell lung cancer
-
Azzoli CG, Temin S, Aliff T, et al. 2011 focused update of 2009 American Society Of Clinical Oncology clinical practice guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol. 2011;29(28):3825- 3831.
-
(2011)
J Clin Oncol
, vol.129
, Issue.28
, pp. 3825-3831
-
-
Azzoli, C.G.1
Temin, S.2
Aliff, T.3
-
12
-
-
84855168417
-
Adjuvant chemotherapy for resected non-small-cell lung cancer: Future perspectives for clinical research
-
Bonomi M, Pilotto S, Milella M, et al. Adjuvant chemotherapy for resected non-small-cell lung cancer: future perspectives for clinical research. J Exp Clin Cancer Res. 2011;30:115.
-
(2011)
J Exp Clin Cancer Res
, Issue.30
, pp. 115
-
-
Bonomi, M.1
Pilotto, S.2
Milella, M.3
-
13
-
-
3242803674
-
Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: A meta-analysis
-
Delbaldo C, Michiels S, Syz N, Soria JC, Le Chevalier T, Pignon JP. Benefits of adding a drug to a single-agent or a 2-agent chemotherapy regimen in advanced non-small-cell lung cancer: a meta-analysis. JAMA. 2004;292(4):470-484.
-
(2004)
JAMA
, vol.292
, Issue.4
, pp. 470-484
-
-
Delbaldo, C.1
Michiels, S.2
Syz, N.3
Soria, J.C.4
Le Chevalier, T.5
Pignon, J.P.6
-
14
-
-
84865681882
-
Adjuvant chemotherapy for surgically resected nonsmall cell lung cancer
-
Heon S, Johnson BE. Adjuvant chemotherapy for surgically resected nonsmall cell lung cancer. J Thorac Cardiovasc Surg. 2012.
-
(2012)
J Thorac Cardiovasc Surg
-
-
Heon, S.1
Johnson, B.E.2
-
15
-
-
79955656558
-
Maintenance therapy in NSCLC:Why? to whom? which agent?
-
Novello S, Milella M, Tiseo M, et al. Maintenance therapy in NSCLC: why? to whom? which agent? J Exp Clin Cancer Res. 2011;30:50.
-
(2011)
J Exp Clin Cancer Res
, Issue.30
, pp. 50
-
-
Novello, S.1
Milella, M.2
Tiseo, M.3
-
16
-
-
80555136679
-
A decade of advances in treatment of early-stage lung cancer
-
Paoletti L, Pastis NJ, Denlinger CE, Silvestri GA. A decade of advances in treatment of early-stage lung cancer. Clin Chest Med. 2011;32(4):827-838.
-
(2011)
Clin Chest Med
, vol.32
, Issue.4
, pp. 827-838
-
-
Paoletti, L.1
Pastis, N.J.2
Denlinger, C.E.3
Silvestri, G.A.4
-
17
-
-
80054935174
-
Subtyping of non-small cell lung carcinoma: A comparison of small biopsy and cytology specimens
-
Sigel CS, Moreira AL, Travis WD, et al. Subtyping of non-small cell lung carcinoma: a comparison of small biopsy and cytology specimens. J Thorac Oncol. 2011;6(11):1849-1856.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.11
-
-
Sigel, C.S.1
Moreira, A.L.2
Travis, W.D.3
-
18
-
-
77950999338
-
Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: A paradigm shift
-
Travis WD, Rekhtman N, Riley GJ, et al. Pathologic diagnosis of advanced lung cancer based on small biopsies and cytology: a paradigm shift. J Thorac Oncol. 2010;5(4):411-414.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.4
, pp. 411-414
-
-
Travis, W.D.1
Rekhtman, N.2
Riley, G.J.3
-
19
-
-
0027491260
-
How reliable is the diagnosis of lung cancer using small biopsy specimens?:Report of a UKCCCR lung cancer working party
-
Thomas JS, Lamb D, Ashcroft T, et al. How reliable is the diagnosis of lung cancer using small biopsy specimens?: report of a UKCCCR lung cancer working party. Thorax. 1993;48(11):1135-1139.
-
(1993)
Thorax
, vol.48
, Issue.11
, pp. 1135-1139
-
-
Thomas, J.S.1
Lamb, D.2
Ashcroft, T.3
-
20
-
-
70349679207
-
Carcinoma NOS is a common histologic diagnosis and is increasing in proportion among non-small cell lung cancer histologies
-
Ou SH, Zell JA. Carcinoma NOS is a common histologic diagnosis and is increasing in proportion among non-small cell lung cancer histologies. J Thorac Oncol. 2009;4(10):1202-1211.
-
(2009)
J Thorac Oncol
, vol.4
, Issue.10
, pp. 1202-1211
-
-
Ou, S.H.1
Zell, J.A.2
-
21
-
-
84857794792
-
P40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma
-
Bishop JA, Teruya-Feldstein J, Westra WH, Pelosi G, Travis WD, Rekhtman N. p40 (DeltaNp63) is superior to p63 for the diagnosis of pulmonary squamous cell carcinoma. Mod Pathol. 2012;25(3):405-415.
-
(2012)
Mod Pathol
, vol.25
, Issue.3
, pp. 405-415
-
-
Bishop, J.A.1
Teruya-Feldstein, J.2
Westra, W.H.3
Pelosi, G.4
Travis, W.D.5
Rekhtman, N.6
-
22
-
-
80053570615
-
Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens
-
Rekhtman N, Ang DC, Sima CS, Travis WD, Moreira AL. Immunohistochemical algorithm for differentiation of lung adenocarcinoma and squamous cell carcinoma based on large series of whole-tissue sections with validation in small specimens. Mod Pathol. 2011;24(10):1348-1359.
-
Mod Pathol
, vol.24
, Issue.10
, pp. 1348-1359
-
-
Rekhtman, N.1
Ang, D.C.2
Sima, C.S.3
Travis, W.D.4
Moreira, A.L.5
-
23
-
-
84856617883
-
A new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: evaluation of 1674 cases by tissue microarray
-
Turner BM, Cagle PT, Sainz IM, Fukuoka J, Shen SS, Jagirdar J. Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of primary pulmonary carcinoma: evaluation of 1674 cases by tissue microarray. Arch Pathol Lab Med. 2012;136(2):163-171.
-
(2012)
Arch Pathol Lab Med
, vol.136
, Issue.2
, pp. 163-171
-
-
Turner, B.M.1
Cagle, P.T.2
Sainz, I.M.3
Fukuoka, J.4
Shen, S.S.5
Jagirdar, J.6
Napsin, A.7
-
24
-
-
79951862254
-
The evolving role of histology in the management of advanced non-small-cell lung cancer
-
Langer CJ, Besse B, Gualberto A, Brambilla E, Soria JC. The evolving role of histology in the management of advanced non-small-cell lung cancer. J Clin Oncol. 2010;28(36):5311-5320.
-
(2010)
J Clin Oncol
, vol.28
, Issue.36
, pp. 5311-5320
-
-
Langer, C.J.1
Besse, B.2
Gualberto, A.3
Brambilla, E.4
Soria, J.C.5
-
25
-
-
70350225538
-
Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: A randomised, double-blind, phase 3 study
-
Ciuleanu T, Brodowicz T, Zielinski C, et al. Maintenance pemetrexed plus best supportive care versus placebo plus best supportive care for non-small-cell lung cancer: a randomised, double-blind, phase 3 study. Lancet. 2009;374(9699): 1432-1440.
-
(2009)
Lancet
, vol.374
, Issue.9699
, pp. 1432-1440
-
-
Ciuleanu, T.1
Brodowicz, T.2
Zielinski, C.3
-
26
-
-
2442661845
-
Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy
-
Hanna N, Shepherd FA, Fossella FV, et al. Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy. J Clin Oncol. 2004;22(9):1589-1597.
-
(2004)
J Clin Oncol
, vol.22
, Issue.9
, pp. 1589-1597
-
-
Hanna, N.1
Shepherd, F.A.2
Fossella, F.V.3
-
27
-
-
64049115311
-
The differential efficacy of pemetrexed according to NSCLC histology: A review of two phase III studies
-
Scagliotti G, Hanna N, Fossella F, et al. The differential efficacy of pemetrexed according to NSCLC histology: a review of two phase III studies. Oncologist. 2009;14(3):253-263.
-
(2009)
Oncologist
, vol.14
, Issue.3
, pp. 253-263
-
-
Scagliotti, G.1
Hanna, N.2
Fossella, F.3
-
28
-
-
77949624488
-
Prognostic and predictive factors in a randomized phase III trial comparing cisplatin-pemetrexed versus cisplatin-gemcitabine in advanced non-small-cell lung cancer
-
Syrigos KN, Vansteenkiste J, Parikh P, et al. Prognostic and predictive factors in a randomized phase III trial comparing cisplatin-pemetrexed versus cisplatin-gemcitabine in advanced non-small-cell lung cancer. Ann Oncol. 2010; 21(3):556-561.
-
(2010)
Ann Oncol
, vol.21
, Issue.3
, pp. 556-561
-
-
Syrigos, K.N.1
Vansteenkiste, J.2
Parikh, P.3
-
29
-
-
34447130180
-
FDA drug approval summary: Bevacizumab (Avastin) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer
-
Cohen MH, Gootenberg J, Keegan P, Pazdur R. FDA drug approval summary: bevacizumab (Avastin) plus carboplatin and paclitaxel as first-line treatment of advanced/metastatic recurrent nonsquamous non-small cell lung cancer. Oncologist. 2007;12(6):713-718.
-
(2007)
Oncologist
, vol.12
, Issue.6
, pp. 713-718
-
-
Cohen, M.H.1
Gootenberg, J.2
Keegan, P.3
Pazdur, R.4
-
30
-
-
78049382933
-
Increased risk of serious hemorrhage with bevacizumab in cancer patients: A meta-analysis
-
Hapani S, Sher A, Chu D, Wu S. Increased risk of serious hemorrhage with bevacizumab in cancer patients: a meta-analysis. Oncology. 2010;79(1-2): 27-38.
-
(2010)
Oncology
, vol.79
, Issue.1-2
, pp. 27-38
-
-
Hapani, S.1
Sher, A.2
Chu, D.3
Wu, S.4
-
31
-
-
2942657615
-
Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic nonsmall- cell lung cancer
-
Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic nonsmall- cell lung cancer. J Clin Oncol. 2004;22(11):2184-2191.
-
(2004)
J Clin Oncol
, vol.22
, Issue.11
, pp. 2184-2191
-
-
Johnson, D.H.1
Fehrenbacher, L.2
Novotny, W.F.3
-
32
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med. 2006;355(24):2542- 2550
-
(2006)
N Engl J Med
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
-
33
-
-
63049122188
-
Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with carboplatin and paclitaxel plus bevacizumab
-
Sandler AB, Schiller JH, Gray R, et al. Retrospective evaluation of the clinical and radiographic risk factors associated with severe pulmonary hemorrhage in first-line advanced, unresectable non-small-cell lung cancer treated with carboplatin and paclitaxel plus bevacizumab. J Clin Oncol. 2009; 27(9):1405-1412.
-
(2009)
J Clin Oncol
, vol.27
, Issue.9
, pp. 1405-1412
-
-
Sandler, A.B.1
Schiller, J.H.2
Gray, R.3
-
34
-
-
77955109217
-
Biomarkers are here to stay for clinical research and standard care
-
Bunn PA Jr, Hirsch FR, Doebele RC, Camidge DR, Varella-Garcia M, Franklin W. Biomarkers are here to stay for clinical research and standard care. J Thorac Oncol. 2010;5(8):1113-1115.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.8
, pp. 1113-1115
-
-
Jr.Bunn, P.A.1
Hirsch, F.R.2
Doebele, R.C.3
Camidge, D.R.4
Varella-Garcia, M.5
Franklin, W.6
-
35
-
-
77954495172
-
Targeted therapies in lung cancer
-
Chirieac LR, Dacic S. Targeted therapies in lung cancer. Surg Pathol Clin. 2010;3(1):71-82.
-
(2010)
Surg Pathol Clin
, vol.3
, Issue.1
, pp. 71-82
-
-
Chirieac, L.R.1
Dacic, S.2
-
36
-
-
79956335981
-
Molecular diagnostics of lung carcinomas
-
Dacic S. Molecular diagnostics of lung carcinomas. Arch Pathol Lab Med. 2011;135(5):622-629.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.5
, pp. 622-629
-
-
Dacic, S.1
-
37
-
-
80055099272
-
Lung carcinoma morphology or mutational profile: That is the question
-
Dacic S. Lung carcinoma morphology or mutational profile: that is the question. Arch Pathol Lab Med. 2011;135(10):1242-1243.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.10
, pp. 1242-1243
-
-
Dacic, S.1
-
38
-
-
83755225553
-
NCCN task force report: Evaluating the clinical utility of tumor markers in oncology
-
quiz S33
-
Febbo PG, Ladanyi M, Aldape KD, et al. NCCN task force report: evaluating the clinical utility of tumor markers in oncology. J Natl Compr Canc Netw. 2011;9(suppl 5):S1-S32; quiz S33.
-
(2011)
J Natl Compr Canc Netw
, vol.9
, Issue.SUPPL. 5
-
-
Febbo, P.G.1
Ladanyi, M.2
Aldape, K.D.3
-
39
-
-
77958072139
-
The tissue is the issue: Personalized medicine for non-small cell lung cancer
-
Hirsch FR, Wynes MW, Gandara DR, Bunn PA Jr. The tissue is the issue: personalized medicine for non-small cell lung cancer. Clin Cancer Res. 2010; 16(20):4909-4911.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.20
, pp. 4909-4911
-
-
Hirsch, F.R.1
Wynes, M.W.2
Gandara, D.R.3
Bunn Jr., P.A.4
-
40
-
-
84857043356
-
Personalized medicine for lung cancer: New challenges for pathology
-
Kerr KM. Personalized medicine for lung cancer: new challenges for pathology. Histopathology. 2012;60(4):531-546.
-
(2012)
Histopathology
, vol.60
, Issue.4
, pp. 531-546
-
-
Kerr, K.M.1
-
41
-
-
79952260258
-
Targeted therapy: An evolving world of lung cancer
-
Lam KC, Mok TS. Targeted therapy: an evolving world of lung cancer. Respirology. 2011;16(1):13-21.
-
(2011)
Respirology
, vol.16
, Issue.1
, pp. 13-21
-
-
Lam, K.C.1
Mok, T.S.2
-
42
-
-
77958102568
-
Personalized medicine for nonsmall- cell lung cancer
-
Mok TS, Zhou Q, Leung L, Loong HH. Personalized medicine for nonsmall- cell lung cancer. Expert Rev Anticancer Ther. 2010;10(10):1601-1611.
-
(2010)
Expert Rev Anticancer Ther
, vol.10
, Issue.10
, pp. 1601-1611
-
-
Mok, T.S.1
Zhou, Q.2
Leung, L.3
Loong, H.H.4
-
43
-
-
84860582939
-
Advances in treatment of lung cancer with targeted therapy
-
Cagle PT, Chirieac LR. Advances in treatment of lung cancer with targeted therapy. Arch Pathol Lab Med. 2012;136(5):504-509.
-
(2012)
Arch Pathol Lab Med
, vol.136
, Issue.5
, pp. 504-509
-
-
Cagle, P.T.1
Chirieac, L.R.2
-
44
-
-
79954626149
-
Pathological diagnosis and classification of lung cancer in small biopsies and cytology: Strategic management of tissue for molecular testing
-
Travis WD, Rekhtman N. Pathological diagnosis and classification of lung cancer in small biopsies and cytology: Strategic management of tissue for molecular testing. Semin Respir Crit Care Med. 2011;32(1):22-31.
-
(2011)
Semin Respir Crit Care Med
, vol.32
, Issue.1
, pp. 22-31
-
-
Travis, W.D.1
Rekhtman, N.2
-
45
-
-
84355161627
-
The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC
-
Gately K, O'Flaherty J, Cappuzzo F, Pirker R, Kerr K, O'Byrne K. The role of the molecular footprint of EGFR in tailoring treatment decisions in NSCLC. J Clin Pathol. 2012;65(1):1-7.
-
(2012)
J Clin Pathol
, vol.65
, Issue.1
, pp. 1-7
-
-
Gately, K.1
O'Flaherty, J.2
Cappuzzo, F.3
Pirker, R.4
Kerr, K.5
O'Byrne, K.6
-
46
-
-
65349161510
-
EGFR testing in lung cancer is ready for prime time
-
Hirsch FR, Bunn PA Jr. EGFR testing in lung cancer is ready for prime time. Lancet Oncol. 2009;10(5):432-433.
-
(2009)
Lancet Oncol
, vol.10
, Issue.5
, pp. 432-433
-
-
Hirsch, F.R.1
Jr.Bunn, P.A.2
-
47
-
-
0041633499
-
Erlotinib: A new therapeutic approach for non-small cell lung cancer
-
Bonomi P. Erlotinib: A new therapeutic approach for non-small cell lung cancer. Expert Opin Investig Drugs. 2003;12(8):1395-1401.
-
(2003)
Expert Opin Investig Drugs
, vol.12
, Issue.8
, pp. 1395-1401
-
-
Bonomi, P.1
-
48
-
-
0141447421
-
Clinically meaningful response to the EGFR tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in non small cell lung cancer
-
Gelibter A, Ceribelli A, Milella M, Mottolese M, Vocaturo A, Cognetti F. Clinically meaningful response to the EGFR tyrosine kinase inhibitor gefitinib ('Iressa', ZD1839) in non small cell lung cancer. J Exp Clin Cancer Res. 2003; 22(3):481-485.
-
(2003)
J Exp Clin Cancer Res
, vol.22
, Issue.3
, pp. 481-485
-
-
Gelibter, A.1
Ceribelli, A.2
Milella, M.3
Mottolese, M.4
Vocaturo, A.5
Cognetti, F.6
-
49
-
-
0141534352
-
Development of the epidermal growth factor receptor inhibitor tarceva (OSI-774)
-
Grunwald V, Hidalgo M. Development of the epidermal growth factor receptor inhibitor tarceva (OSI-774). Adv Exp Med Biol. 2003;532:235-246.
-
(2003)
Adv Exp Med Biol
, vol.532
, pp. 235-246
-
-
Grunwald, V.1
Hidalgo, M.2
-
50
-
-
0038343121
-
Erlotinib (Tarceva): An update on the clinical trial program
-
Herbst RS. Erlotinib (Tarceva): An update on the clinical trial program. Semin Oncol. 2003;30(3)(suppl 7):34-46.
-
(2003)
Semin Oncol
, vol.30
, Issue.3 SUPPL. 7
, pp. 34-46
-
-
Herbst, R.S.1
-
52
-
-
0036368423
-
ZD1839 (Iressa) in non-small cell lung cancer
-
Herbst RS, Kies MS. ZD1839 (Iressa) in non-small cell lung cancer. Oncologist. 2002;7(suppl 4):9-15.
-
(2002)
Oncologist
, vol.7
, Issue.SUPPL. 4
, pp. 9-15
-
-
Herbst, R.S.1
Kies, M.S.2
-
53
-
-
0142055937
-
Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: A randomized trial
-
Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA. 2003;290(16):2149- 2158.
-
(2003)
JAMA
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
-
54
-
-
0142151435
-
Gefitinib therapy for advanced non-small-cell lung cancer
-
Liu CY, Seen S. Gefitinib therapy for advanced non-small-cell lung cancer. Ann Pharmacother. 2003;37(11):1644-1653.
-
(2003)
Ann Pharmacother
, vol.37
, Issue.11
, pp. 1644-1653
-
-
Liu, C.Y.1
Seen, S.2
-
55
-
-
0038021580
-
ZD1839, A novel, oral epidermal growth factor receptor-tyrosine kinase inhibitor, as salvage treatment in patients with advanced non-small cell lung cancer: Experience from a single center participating in a compassionate use program
-
Pallis AG, Mavroudis D, Androulakis N, et al. ZD1839, a novel, oral epidermal growth factor receptor-tyrosine kinase inhibitor, as salvage treatment in patients with advanced non-small cell lung cancer: experience from a single center participating in a compassionate use program. Lung Cancer. 2003;40(3): 301-307.
-
(2003)
Lung Cancer
, vol.40
, Issue.3
, pp. 301-307
-
-
Pallis, A.G.1
Mavroudis, D.2
Androulakis, N.3
-
56
-
-
1542648232
-
Clinical experience with the HER1/EGFR tyrosine kinase inhibitor erlotinib
-
(Williston Park)
-
Sandler A. Clinical experience with the HER1/EGFR tyrosine kinase inhibitor erlotinib. Oncology (Williston Park). 2003;17(11)(suppl 12):17-22.
-
(2003)
Oncology
, vol.17
, Issue.11 SUPPL. 12
, pp. 17-22
-
-
Sandler, A.1
-
57
-
-
0346991841
-
EGFR Tyrosine Kinase Inhibitor gefitinib (Iressa) for cancer therapy
-
Yano S, Yamaguchi M, Dong RP. EGFR tyrosine kinase inhibitor "gefitinib (Iressa)" for cancer therapy. Nihon Yakurigaku Zasshi. 2003;122(6):491-497.
-
(2003)
Nihon Yakurigaku Zasshi
, vol.122
, Issue.6
, pp. 491-497
-
-
Yano, S.1
Yamaguchi, M.2
Dong, R.P.3
-
58
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 2004;350(21):2129-2139.
-
(2004)
N Engl J Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
59
-
-
2342624080
-
EGFR mutations in lung cancer, Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304(5676): 1497-1500.
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
60
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci U S A. 2004; 101(36):13306-13311.
-
(2004)
Proc Natl Acad Sci
, vol.101
, Issue.36
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
-
62
-
-
40949147677
-
The role of gefitinib in the management of Asian patients with non-small cell lung cancer
-
Chang AY. The role of gefitinib in the management of Asian patients with non-small cell lung cancer. Expert Opin Investig Drugs. 2008;17(3):401-411.
-
(2008)
Expert Opin Investig Drugs
, vol.17
, Issue.3
, pp. 401-411
-
-
Chang, A.Y.1
-
63
-
-
34548484397
-
Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers
-
Costa DB, Kobayashi S, Tenen DG, Huberman MS. Pooled analysis of the prospective trials of gefitinib monotherapy for EGFR-mutant non-small cell lung cancers. Lung Cancer. 2007;58(1):95-103.
-
(2007)
Lung Cancer
, vol.58
, Issue.1
, pp. 95-103
-
-
Costa, D.B.1
Kobayashi, S.2
Tenen, D.G.3
Huberman, M.S.4
-
64
-
-
58149234399
-
Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib
-
Costa DB, Nguyen KS, Cho BC, et al. Effects of erlotinib in EGFR mutated non-small cell lung cancers with resistance to gefitinib. Clin Cancer Res. 2008; 14(21):7060-7067.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.21
, pp. 7060-7067
-
-
Costa, D.B.1
Nguyen, K.S.2
Cho, B.C.3
-
65
-
-
24944440830
-
Tribute: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol. 2005; 23(25):5892-5899.
-
(2005)
J Clin Oncol
, vol.23
, Issue.25
, pp. 5892-5899
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
-
66
-
-
12744255161
-
Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer
-
Perez-Soler R. Phase II clinical trial data with the epidermal growth factor receptor tyrosine kinase inhibitor erlotinib (OSI-774) in non-small-cell lung cancer. Clin Lung Cancer. 2004;6(suppl 1):S20-S23.
-
(2004)
Clin Lung Cancer
, vol.6
, Issue.SUPPL. 1
-
-
Perez-Soler, R.1
-
67
-
-
47249105667
-
Erlotinib: An EGF receptor tyrosine kinase inhibitor in non-small-cell lung cancer treatment
-
Schettino C, Bareschino MA, Ricci V, Ciardiello F. Erlotinib: an EGF receptor tyrosine kinase inhibitor in non-small-cell lung cancer treatment. Expert Rev Respir Med. 2008;2(2):167-178.
-
(2008)
Expert Rev Respir Med
, vol.2
, Issue.2
, pp. 167-178
-
-
Schettino, C.1
Bareschino, M.A.2
Ricci, V.3
Ciardiello, F.4
-
68
-
-
39849097128
-
Epidermal growth factor receptor inhibitors in the treatment of lung cancer: Reality and hopes
-
Wheatley-Price P, Shepherd FA. Epidermal growth factor receptor inhibitors in the treatment of lung cancer: reality and hopes. Curr Opin Oncol. 2008;20(2):162-175.
-
(2008)
Curr Opin Oncol
, vol.20
, Issue.2
, pp. 162-175
-
-
Wheatley-Price, P.1
Shepherd, F.A.2
-
69
-
-
79960218807
-
Genotype-driven therapies for non-small cell lung cancer: Focus on EGFR, KRAS and ALK gene abnormalities
-
Gaughan EM, Costa DB. Genotype-driven therapies for non-small cell lung cancer: focus on EGFR, KRAS and ALK gene abnormalities. Ther Adv Med Oncol. 2011;3(3):113-125.
-
(2011)
Ther Adv Med Oncol
, vol.3
, Issue.3
, pp. 113-125
-
-
Gaughan, E.M.1
Costa, D.B.2
-
70
-
-
79960702788
-
Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS)
-
Fukuoka M, Wu YL, Thongprasert S, et al. Biomarker analyses and final overall survival results from a phase III, randomized, open-label, first-line study of gefitinib versus carboplatin/paclitaxel in clinically selected patients with advanced non-small-cell lung cancer in Asia (IPASS). J Clin Oncol. 2011; 29(21):2866-2874.
-
(2011)
J Clin Oncol
, vol.29
, Issue.21
, pp. 2866-2874
-
-
Fukuoka, M.1
Wu, Y.L.2
Thongprasert, S.3
-
71
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med. 2009;361(10):947-957.
-
(2009)
N Engl J Med
, vol.361
, Issue.10
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
72
-
-
75249087060
-
Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): An open label, randomised phase 3 trial
-
Mitsudomi T, Morita S, Yatabe Y, et al. Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial. Lancet Oncol. 2010;11(2):121-128.
-
(2010)
Lancet Oncol
, vol.11
, Issue.2
, pp. 121-128
-
-
Mitsudomi, T.1
Morita, S.2
Yatabe, Y.3
-
73
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med. 2010;362(25): 2380-2388.
-
(2010)
N Engl J Med
, vol.362
, Issue.25
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
-
74
-
-
79960889662
-
Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): A multicentre, open-label, randomised, phase 3 study
-
Zhou C, Wu YL, Chen G, et al. Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study. Lancet Oncol. 2011;12(8):735-742.
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 735-742
-
-
Zhou, C.1
Wu, Y.L.2
Chen, G.3
-
75
-
-
84857502654
-
Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): A multicentre, openlabel, randomised phase 3 trial
-
Rosell R, Carcereny E, Gervais R, et al. Erlotinib versus standard chemotherapy as first-line treatment for European patients with advanced EGFR mutation-positive non-small-cell lung cancer (EURTAC): a multicentre, openlabel, randomised phase 3 trial. Lancet Oncol. 2012;13(3):239-246.
-
(2012)
Lancet Oncol
, vol.13
, Issue.3
, pp. 239-246
-
-
Rosell, R.1
Carcereny, E.2
Gervais, R.3
-
76
-
-
84862580343
-
Clinical outcomes with erlotinib in patients with epidermal growth factor receptor mutation
-
Mok TS, D'arcangelo M, Califano R. Clinical outcomes with erlotinib in patients with epidermal growth factor receptor mutation. Drugs. 2012;72(suppl 1):3-10.
-
(2012)
Drugs
, vol.72
, Issue.SUPPL. 1
, pp. 3-10
-
-
Mok, T.S.1
D'arcangelo, M.2
Califano, R.3
-
77
-
-
75249084998
-
Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer
-
Mok TS, Wu YL, Yu CJ, et al. Randomized, placebo-controlled, phase II study of sequential erlotinib and chemotherapy as first-line treatment for advanced non-small-cell lung cancer. J Clin Oncol. 2009;27(30):5080-5087.
-
(2009)
J Clin Oncol
, vol.27
, Issue.30
, pp. 5080-5087
-
-
Mok, T.S.1
Wu, Y.L.2
Yu, C.J.3
-
78
-
-
77951951659
-
Clinical outcomes in nonsmall- cell lung cancer patients with EGFR mutations: Pooled analysis
-
Paz-Ares L, Soulieres D, Melezinek I, et al. Clinical outcomes in nonsmall- cell lung cancer patients with EGFR mutations: pooled analysis. J Cell Mol Med. 2010;14(1-2):51-69.
-
(2010)
J Cell Mol Med
, vol.14
, Issue.1-2
, pp. 51-69
-
-
Paz-Ares, L.1
Soulieres, D.2
Melezinek, I.3
-
79
-
-
79955983366
-
Molecular characteristics predict clinical outcomes: Prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene
-
Rizvi NA, Rusch V, Pao W, et al. Molecular characteristics predict clinical outcomes: Prospective trial correlating response to the EGFR tyrosine kinase inhibitor gefitinib with the presence of sensitizing mutations in the tyrosine binding domain of the EGFR gene. Clin Cancer Res. 2011;17(10):3500- 3506.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.10
, pp. 3500-3506
-
-
Rizvi, N.A.1
Rusch, V.2
Pao, W.3
-
80
-
-
80051750848
-
Low-dose gefitinib treatment for patients with advanced non-small cell lung cancer harboring sensitive epidermal growth factor receptor mutations
-
Satoh H, Inoue A, Kobayashi K, et al. Low-dose gefitinib treatment for patients with advanced non-small cell lung cancer harboring sensitive epidermal growth factor receptor mutations. J Thorac Oncol. 2011;6(8):1413-1417.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.8
, pp. 1413-1417
-
-
Satoh, H.1
Inoue, A.2
Kobayashi, K.3
-
81
-
-
80052194689
-
Outcome of advanced NSCLC patients harboring sensitizing EGFR mutations randomized to EGFR tyrosine kinase inhibitors or chemotherapy as first-line treatment: A meta-analysis
-
Bria E, Milella M, Cuppone F, et al. Outcome of advanced NSCLC patients harboring sensitizing EGFR mutations randomized to EGFR tyrosine kinase inhibitors or chemotherapy as first-line treatment: a meta-analysis. Ann Oncol. 2011;22(10):2277-2285.
-
(2011)
Ann Oncol
, vol.22
, Issue.10
, pp. 2277-2285
-
-
Bria, E.1
Milella, M.2
Cuppone, F.3
-
82
-
-
84865154870
-
First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: The TORCH randomized trial
-
published online ahead of print August 20, 2012
-
Gridelli C, Ciardiello F, Gallo C, et al. First-line erlotinib followed by second-line cisplatin-gemcitabine chemotherapy in advanced non-small-cell lung cancer: the TORCH randomized trial [published online ahead of print August 20, 2012]. J Clin Oncol. 2012;30(24):3002-3011.
-
(2012)
J Clin Oncol
, vol.30
, Issue.24
, pp. 3002-3011
-
-
Gridelli, C.1
Ciardiello, F.2
Gallo, C.3
-
83
-
-
80052972204
-
A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer
-
Hirsch FR, Kabbinavar F, Eisen T, et al. A randomized, phase II, biomarker-selected study comparing erlotinib to erlotinib intercalated with chemotherapy in first-line therapy for advanced non-small-cell lung cancer. J Clin Oncol. 2011;29(26):3567-3573.
-
(2011)
J Clin Oncol
, vol.29
, Issue.26
, pp. 3567-3573
-
-
Hirsch, F.R.1
Kabbinavar, F.2
Eisen, T.3
-
84
-
-
63049132774
-
First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy
-
Inoue A, Kobayashi K, Usui K, et al. First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. J Clin Oncol. 2009;27(9):1394- 1400.
-
(2009)
J Clin Oncol
, vol.27
, Issue.9
, pp. 1394-1400
-
-
Inoue, A.1
Kobayashi, K.2
Usui, K.3
-
85
-
-
84870888770
-
Treatment paradigms for patients with metastatic non-smallcell lung cancer: First-, second-, and third-line
-
Leighl NB. Treatment paradigms for patients with metastatic non-smallcell lung cancer: First-, second-, and third-line. Curr Oncol. 2012;19(suppl 1): S52-S58.
-
(2012)
Curr Oncol
, vol.19
, Issue.1 SUPPL.
-
-
Leighl, N.B.1
-
86
-
-
84858766310
-
EGFR molecular profiling in advanced NSCLC: A prospective phase II study in molecularly/clinically selected patients pretreated with chemotherapy
-
Milella M, Nuzzo C, Bria E, et al. EGFR molecular profiling in advanced NSCLC: a prospective phase II study in molecularly/clinically selected patients pretreated with chemotherapy. J Thorac Oncol. 2012;7(4):672-680.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.4
, pp. 672-680
-
-
Milella, M.1
Nuzzo, C.2
Bria, E.3
-
87
-
-
78751578969
-
Reflex testing of resected stage I through III lung adenocarcinomas for EGFR and KRAS mutation: Report on initial experience and clinical utility at a single center
-
D'Angelo SP, Park B, Azzoli CG, et al. Reflex testing of resected stage I through III lung adenocarcinomas for EGFR and KRAS mutation: report on initial experience and clinical utility at a single center. J Thorac Cardiovasc Surg. 2011; 141(2):476-480.
-
(2011)
J Thorac Cardiovasc Surg
, vol.141
, Issue.2
, pp. 476-480
-
-
D'angelo, S.P.1
Park, B.2
Azzoli, C.G.3
-
88
-
-
79951773393
-
Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations
-
Janjigian YY, Park BJ, Zakowski MF, et al. Impact on disease-free survival of adjuvant erlotinib or gefitinib in patients with resected lung adenocarcinomas that harbor EGFR mutations. J Thorac Oncol. 2011;6(3):569-575.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.3
, pp. 569-575
-
-
Janjigian, Y.Y.1
Park, B.J.2
Zakowski, M.F.3
-
89
-
-
49649127657
-
Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer
-
Engelman JA, Janne PA. Mechanisms of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer. Clin Cancer Res. 2008;14(10):2895-2899.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.10
, pp. 2895-2899
-
-
Engelman, J.A.1
Janne, P.A.2
-
90
-
-
74949110711
-
Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall- cell lung cancer
-
Jackman D, Pao W, Riely GJ, et al. Clinical definition of acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in nonsmall- cell lung cancer. J Clin Oncol. 2010;28(2):357-360.
-
(2010)
J Clin Oncol
, vol.28
, Issue.2
, pp. 357-360
-
-
Jackman, D.1
Pao, W.2
Riely, G.J.3
-
91
-
-
79958076056
-
Studies for mechanism of drug resistance to EGFR-TKI
-
Yano S. Studies for mechanism of drug resistance to EGFR-TKI. Gan To Kagaku Ryoho. 2010;37(8):1463-1466.
-
(2010)
Gan To Kagaku Ryoho
, vol.37
, Issue.8
, pp. 1463-1466
-
-
Yano, S.1
-
92
-
-
84858201603
-
EGFR exon 19 insertions: A new family of sensitizing EGFR mutations in lung adenocarcinoma
-
He M, Capelletti M, Nafa K, et al. EGFR exon 19 insertions: a new family of sensitizing EGFR mutations in lung adenocarcinoma. Clin Cancer Res. 2012; 18(6):1790-1797.
-
Clin Cancer Res
, vol.18
, Issue.6
, pp. 1790-1797
-
-
He, M.1
Capelletti, M.2
Nafa, K.3
-
93
-
-
77958185649
-
Consensus for EGFR mutation testing in non-small cell lung cancer: Results from a european workshop
-
Pirker R, Herth FJ, Kerr KM, et al. Consensus for EGFR mutation testing in non-small cell lung cancer: results from a European workshop. J Thorac Oncol. 2010;5(10):1706-1713.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.10
, pp. 1706-1713
-
-
Pirker, R.1
Herth, F.J.2
Kerr, K.M.3
-
94
-
-
35548962203
-
Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer
-
Mitsudomi T, Yatabe Y. Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer. Cancer Sci. 2007;98(12): 1817-1824.
-
(2007)
Cancer Sci
, vol.98
, Issue.12
, pp. 1817-1824
-
-
Mitsudomi, T.1
Yatabe, Y.2
-
95
-
-
77349091545
-
Biological and clinical significance of KRAS mutations in lung cancer: An oncogenic driver that contrasts with EGFR mutation
-
Suda K, Tomizawa K, Mitsudomi T. Biological and clinical significance of KRAS mutations in lung cancer: an oncogenic driver that contrasts with EGFR mutation. Cancer Metastasis Rev. 2010;29(1):49-60.
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.1
, pp. 49-60
-
-
Suda, K.1
Tomizawa, K.2
Mitsudomi, T.3
-
96
-
-
78651087933
-
Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans.
-
Reinersman JM, Johnson ML, Riely GJ, et al. Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans. J Thorac Oncol. 2011;6(1):28-31.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.1
, pp. 28-31
-
-
Reinersman, J.M.1
Johnson, M.L.2
Riely, G.J.3
-
97
-
-
77955635233
-
Cancer statistics, 2010
-
Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin. 2010;60(5):277-300.
-
(2010)
CA Cancer J Clin
, vol.60
, Issue.5
, pp. 277-300
-
-
Jemal, A.1
Siegel, R.2
Xu, J.3
Ward, E.4
-
98
-
-
79957510807
-
Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas
-
D'Angelo SP, Pietanza MC, Johnson ML, et al. Incidence of EGFR exon 19 deletions and L858R in tumor specimens from men and cigarette smokers with lung adenocarcinomas. J Clin Oncol. 2011;29(15):2066-2070.
-
(2011)
J Clin Oncol
, vol.29
, Issue.15
, pp. 2066-2070
-
-
D'angelo, S.P.1
Pietanza, M.C.2
Johnson, M.L.3
-
99
-
-
84861856507
-
Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma
-
Girard N, Sima CS, Jackman DM, et al. Nomogram to predict the presence of EGFR activating mutation in lung adenocarcinoma. Eur Respir J. 2012;39(2):366-372.
-
(2012)
Eur Respir J
, vol.39
, Issue.2
, pp. 366-372
-
-
Girard, N.1
Sima, C.S.2
Jackman, D.M.3
-
100
-
-
79955049751
-
Adenosquamous carcinoma of the lung: A microdissection study of KRAS and EGFR mutational and amplification status in a western patient population
-
Tochigi N, Dacic S, Nikiforova M, Cieply KM, Yousem SA. Adenosquamous carcinoma of the lung: a microdissection study of KRAS and EGFR mutational and amplification status in a western patient population. Am J Clin Pathol. 2011;135(5):783-789.
-
(2011)
Am J Clin Pathol
, vol.135
, Issue.5
, pp. 783-789
-
-
Tochigi, N.1
Dacic, S.2
Nikiforova, M.3
Cieply, K.M.4
Yousem, S.A.5
-
101
-
-
84857087591
-
Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: Lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations
-
Rekhtman N, Paik PK, Arcila ME, et al. Clarifying the spectrum of driver oncogene mutations in biomarker-verified squamous carcinoma of lung: lack of EGFR/KRAS and presence of PIK3CA/AKT1 mutations. Clin Cancer Res. 2012; 18(4):1167-1176.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.4
, pp. 1167-1176
-
-
Rekhtman, N.1
Paik, P.K.2
Arcila, M.E.3
-
102
-
-
33751292685
-
Novel D761Yand common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors
-
Balak MN, Gong Y, Riely GJ, et al. Novel D761Yand common secondary T790M mutations in epidermal growth factor receptor-mutant lung adenocarcinomas with acquired resistance to kinase inhibitors. Clin Cancer Res. 2006; 12(21):6494-6501.
-
(2006)
Clin Cancer Res
, vol.12
, Issue.21
, pp. 6494-6501
-
-
Balak, M.N.1
Gong, Y.2
Riely, G.J.3
-
103
-
-
75049083402
-
Clinicopathologic and molecular features of epidermal growth factor receptor T790M mutation and c-MET amplification in tyrosine kinase inhibitor-resistant Chinese non-small cell lung cancer
-
Chen HJ, Mok TS, Chen ZH, et al. Clinicopathologic and molecular features of epidermal growth factor receptor T790M mutation and c-MET amplification in tyrosine kinase inhibitor-resistant Chinese non-small cell lung cancer. Pathol Oncol Res. 2009;15(4):651-658.
-
(2009)
Pathol Oncol Res
, vol.15
, Issue.4
, pp. 651-658
-
-
Chen, H.J.1
Mok, T.S.2
Chen, Z.H.3
-
104
-
-
41949119173
-
Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations
-
author reply,1184-1186
-
Costa DB, Schumer ST, Tenen DG, Kobayashi S. Differential responses to erlotinib in epidermal growth factor receptor (EGFR)-mutated lung cancers with acquired resistance to gefitinib carrying the L747S or T790M secondary mutations. J Clin Oncol. 2008;26(7):1182-1184; author reply 1184-1186.
-
(2008)
J Clin Oncol
, vol.26
, Issue.7
, pp. 1182-1184
-
-
Costa, D.B.1
Schumer, S.T.2
Tenen, D.G.3
Kobayashi, S.4
-
105
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors
-
75ra26
-
Sequist LV, Waltman BA, Dias-Santagata D, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med. 2011;3(75):75ra26.
-
(2011)
Sci Transl Med.
, vol.3
, Issue.75
-
-
Sequist, L.V.1
Waltman, B.A.2
Dias-Santagata, D.3
-
106
-
-
58149333768
-
Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma
-
Bean J, Riely GJ, Balak M, et al. Acquired resistance to epidermal growth factor receptor kinase inhibitors associated with a novel T854A mutation in a patient with EGFR-mutant lung adenocarcinoma. Clin Cancer Res. 2008;14(22): 7519-7525.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.22
, pp. 7519-7525
-
-
Bean, J.1
Riely, G.J.2
Balak, M.3
-
107
-
-
38049150665
-
MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib
-
U S A.
-
Bean J, Brennan C, Shih JY, et al. MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib. Proc Natl Acad Sci U S A. 2007;104(52):20932-20937.
-
(2007)
Proc Natl Acad Sci
, vol.104
, Issue.52
, pp. 20932-20937
-
-
Bean, J.1
Brennan, C.2
Shih, J.Y.3
-
108
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science. 2007;316(5827):1039-1043.
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
-
109
-
-
56449089812
-
Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptoractivating mutations
-
Yano S, Wang W, Li Q, et al. Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptoractivating mutations. Cancer Res. 2008;68(22):9479-9487.
-
(2008)
Cancer Res
, vol.68
, Issue.22
, pp. 9479-9487
-
-
Yano, S.1
Wang, W.2
Li, Q.3
-
110
-
-
81755185464
-
Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort
-
Yano S, Yamada T, Takeuchi S, et al. Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort. J Thorac Oncol. 2011;6(12):2011-2017.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.12
, pp. 2011-2017
-
-
Yano, S.1
Yamada, T.2
Takeuchi, S.3
-
111
-
-
84868121552
-
An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting
-
published online ahead of print July 9, 2012, doi:10.1093/annonc/mds121
-
Goto K, Satouchi M, Ishii G, et al. An evaluation study of EGFR mutation tests utilized for non-small-cell lung cancer in the diagnostic setting [published online ahead of print July 9, 2012]. Ann Oncol. 2012. doi:10.1093/annonc/mds121.
-
(2012)
Ann Oncol
-
-
Goto, K.1
Satouchi, M.2
Ishii, G.3
-
112
-
-
77957316871
-
A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples
-
Ellison G, Donald E, McWalter G, et al. A comparison of ARMS and DNA sequencing for mutation analysis in clinical biopsy samples. J Exp Clin Cancer Res. 2010;29:132.
-
(2010)
J Exp Clin Cancer Res
, vol.29
, pp. 132
-
-
Ellison, G.1
Donald, E.2
McWalter, G.3
-
113
-
-
84863954773
-
Routine EGFR and KRAS mutation analysis using COLD-PCR in non-small cell lung cancer
-
Pennycuick A, Simpson T, Crawley D, et al. Routine EGFR and KRAS mutation analysis using COLD-PCR in non-small cell lung cancer. Int J Clin Pract. 2012;66(8):748-752.
-
(2012)
Int J Clin Pract
, vol.66
, Issue.8
, pp. 748-752
-
-
Pennycuick, A.1
Simpson, T.2
Crawley, D.3
-
114
-
-
80555128926
-
Detection of epidermal growth factor receptor mutations in non-small-cell lung carcinoma by direct sequencing and correlations with clinicopathological characteristics and sample types
-
Sun MH, Yang F, Shen L, et al. Detection of epidermal growth factor receptor mutations in non-small-cell lung carcinoma by direct sequencing and correlations with clinicopathological characteristics and sample types. Zhonghua Bing Li Xue Za Zhi. 2011;40(10):655-659.
-
(2010)
Zhonghua Bing Li Xue Za Zhi
, vol.40
, Issue.10
, pp. 655-659
-
-
Sun, M.H.1
Yang, F.2
Shen, L.3
-
115
-
-
84863726241
-
Optimized algorithm for Sanger sequencing-based EGFR mutation analyses in NSCLC biopsies
-
Warth A, Penzel R, Brandt R, et al. Optimized algorithm for Sanger sequencing-based EGFR mutation analyses in NSCLC biopsies. Virchows Arch. 2012;460(4):407-414.
-
(2012)
Virchows Arch
, vol.460
, Issue.4
, pp. 407-414
-
-
Warth, A.1
Penzel, R.2
Brandt, R.3
-
116
-
-
81155123620
-
Role of genotyping in non-small cell lung cancer treatment: Current status
-
Bonanno L, Favaretto A, Rugge M, Taron M, Rosell R. Role of genotyping in non-small cell lung cancer treatment: current status. Drugs. 2011;71(17): 2231-2246.
-
(2011)
Drugs
, vol.71
, Issue.17
, pp. 2231-2246
-
-
Bonanno, L.1
Favaretto, A.2
Rugge, M.3
Taron, M.4
Rosell, R.5
-
117
-
-
84865783136
-
Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing
-
Corless CL, Spellman PT. Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing. Cancer Discov. 2012;2(1):23-24.
-
(2012)
Cancer Discov
, vol.2
, Issue.1
, pp. 23-24
-
-
Corless, C.L.1
Spellman, P.T.2
-
118
-
-
79958835059
-
Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology
-
Cronin M, Ross JS. Comprehensive next-generation cancer genome sequencing in the era of targeted therapy and personalized oncology. Biomark Med. 2011;5(3):293-305.
-
(2011)
Biomark Med
, vol.5
, Issue.3
, pp. 293-305
-
-
Cronin, M.1
Ross, J.S.2
-
119
-
-
77951982654
-
Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer
-
Lin CH, Yeh KT, Chang YS, Hsu NC, Chang JG. Rapid detection of epidermal growth factor receptor mutations with multiplex PCR and primer extension in lung cancer. J Biomed Sci. 2010;17:37.
-
(2010)
J Biomed Sci
, vol.17
, pp. 37
-
-
Lin, C.H.1
Yeh, K.T.2
Chang, Y.S.3
Hsu, N.C.4
Chang, J.G.5
-
120
-
-
84859644745
-
A SNaPshot into a tumor's genotype: Rapid, comprehensive genotyping possible in routine clinical practice
-
Miller S. A SNaPshot into a tumor's genotype: rapid, comprehensive genotyping possible in routine clinical practice. Bioanalysis. 2011;3(24):2705.
-
(2011)
Bioanalysis
, vol.3
, Issue.24
, pp. 2705
-
-
Miller, S.1
-
121
-
-
83455213560
-
Insights from next generation sequencing of the cancer genome
-
Porteous M. Insights from next generation sequencing of the cancer genome. J R Coll Physicians Edinb. 2011;41(4):323.
-
(2011)
J R Coll Physicians Edinb
, vol.41
, Issue.4
, pp. 323
-
-
Porteous, M.1
-
122
-
-
84866467254
-
Key principles and clinical applications of "nextgeneration" DNA sequencing
-
Rizzo JM, Buck MJ. Key principles and clinical applications of "nextgeneration" DNA sequencing. Cancer Prev Res (Phila). 2012;5(7):887-900.
-
(2012)
Cancer Prev Res
, vol.5
, Issue.7
, pp. 887-900
-
-
Rizzo, J.M.1
Buck, M.J.2
-
123
-
-
82355191818
-
Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice
-
Sequist LV, Heist RS, Shaw AT, et al. Implementing multiplexed genotyping of non-small-cell lung cancers into routine clinical practice. Ann Oncol. 2011;22(12):2616-2624.
-
(2011)
Ann Oncol
, vol.22
, Issue.12
, pp. 2616-2624
-
-
Sequist, L.V.1
Heist, R.S.2
Shaw, A.T.3
-
124
-
-
78651079558
-
A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-smallcell lung cancer
-
Su Z, Dias-Santagata D, Duke M, et al. A platform for rapid detection of multiple oncogenic mutations with relevance to targeted therapy in non-smallcell lung cancer. J Mol Diagn. 2011;13(1):74-84.
-
(2011)
J Mol Diagn
, vol.13
, Issue.1
, pp. 74-84
-
-
Su, Z.1
Dias-Santagata, D.2
Duke, M.3
-
125
-
-
28844449401
-
Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: Molecular analysis of the IDEAL/INTACT gefitinib trials
-
Bell DW, Lynch TJ, Haserlat SM, et al. Epidermal growth factor receptor mutations and gene amplification in non-small-cell lung cancer: molecular analysis of the IDEAL/INTACT gefitinib trials. J Clin Oncol. 2005;23(31):8081- 8092.
-
(2005)
J Clin Oncol
, vol.23
, Issue.31
, pp. 8081-8092
-
-
Bell, D.W.1
Lynch, T.J.2
Haserlat, S.M.3
-
126
-
-
42749085753
-
EGFR FISH versus mutation: Different tests, different endpoints
-
Cappuzzo F. EGFR FISH versus mutation: different tests, different endpoints. Lung Cancer. 2008;60(2):160-165.
-
(2008)
Lung Cancer
, vol.60
, Issue.2
, pp. 160-165
-
-
Cappuzzo, F.1
-
127
-
-
58149151261
-
Fluorescence in situ hybridization subgroup analysis of TRIBUTE, a phase III trial of erlotinib plus carboplatin and paclitaxel in non-small cell lung cancer
-
Hirsch FR, Varella-Garcia M, Dziadziuszko R, et al. Fluorescence in situ hybridization subgroup analysis of TRIBUTE, a phase III trial of erlotinib plus carboplatin and paclitaxel in non-small cell lung cancer. Clin Cancer Res. 2008; 14(19):6317-6323.
-
(2008)
Clin Cancer Res
, vol.14
, Issue.19
, pp. 6317-6323
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Dziadziuszko, R.3
-
128
-
-
84862571677
-
Prognostic and predictive value of KRAS mutations in non-small cell lung cancer
-
Califano R, Landi L, Cappuzzo F. Prognostic and predictive value of KRAS mutations in non-small cell lung cancer. Drugs. 2012;72(suppl 1):28-36.
-
(2012)
Drugs
, vol.72
, Issue.SUPPL.
, pp. 28-36
-
-
Califano, R.1
Landi, L.2
Cappuzzo, F.3
-
129
-
-
84866147012
-
Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype
-
published online ahead of print July 4, 2012, doi:10.1016/j.lungcan.2012. 06.005
-
Metro G, Chiari R, Duranti S, et al. Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype [published online ahead of print July 4, 2012]. Lung Cancer. 2012. doi:10.1016/j.lungcan.2012.06.005.
-
(2012)
Lung Cancer
-
-
Metro, G.1
Chiari, R.2
Duranti, S.3
-
130
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: Is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts PJ, Stinchcombe TE, Der CJ, Socinski MA. Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J Clin Oncol. 2010;28(31): 4769-4777.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4769-4777
-
-
Roberts, P.J.1
Stinchcombe, T.E.2
Der, C.J.3
Socinski, M.A.4
-
131
-
-
80051784829
-
A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of nonsmall cell lung cancer
-
Ellis PM, Blais N, Soulieres D, et al. A systematic review and Canadian consensus recommendations on the use of biomarkers in the treatment of nonsmall cell lung cancer. J Thorac Oncol. 2011;6(8):1379-1391.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.8
, pp. 1379-1391
-
-
Ellis, P.M.1
Blais, N.2
Soulieres, D.3
-
132
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature. 2007;448(7153): 561-566.
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
-
133
-
-
36849065315
-
Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer
-
Rikova K, Guo A, Zeng Q, et al. Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. Cell. 2007;131(6):1190- 1203.
-
(2007)
Cell
, vol.131
, Issue.6
, pp. 1190-1203
-
-
Rikova, K.1
Guo, A.2
Zeng, Q.3
-
134
-
-
48549098388
-
Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer
-
Choi YL, Takeuchi K, Soda M, et al. Identification of novel isoforms of the EML4-ALK transforming gene in non-small cell lung cancer. Cancer Res. 2008; 68(13):4971-4976.
-
(2008)
Cancer Res
, vol.68
, Issue.13
, pp. 4971-4976
-
-
Choi, Y.L.1
Takeuchi, K.2
Soda, M.3
-
135
-
-
63949086127
-
KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer
-
Takeuchi K, Choi YL, Togashi Y, et al. KIF5B-ALK, a novel fusion oncokinase identified by an immunohistochemistry-based diagnostic system for ALK-positive lung cancer. Clin Cancer Res. 2009;15(9):3143-3149.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.9
, pp. 3143-3149
-
-
Takeuchi, K.1
Choi, Y.L.2
Togashi, Y.3
-
136
-
-
84856695102
-
KLC1-ALK: A novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only
-
Togashi Y, Soda M, Sakata S, et al. KLC1-ALK: a novel fusion in lung cancer identified using a formalin-fixed paraffin-embedded tissue only. PLoS One. 2012;7(2):e31323.
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Togashi, Y.1
Soda, M.2
Sakata, S.3
-
137
-
-
63949087355
-
EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset
-
Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology, and young onset. Mod Pathol. 2009;22(4):508-515.
-
(2009)
Mod Pathol
, vol.22
, Issue.4
, pp. 508-515
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
-
138
-
-
37549060017
-
EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers
-
Inamura K, Takeuchi K, Togashi Y, et al. EML4-ALK fusion is linked to histological characteristics in a subset of lung cancers. J Thorac Oncol. 2008;3(1): 13-17.
-
(2008)
J Thorac Oncol
, vol.3
, Issue.1
, pp. 13-17
-
-
Inamura, K.1
Takeuchi, K.2
Togashi, Y.3
-
139
-
-
79955482290
-
Clinicopathologic characteristics and outcomes of patients with anaplastic lymphoma kinase-positive advanced pulmonary adenocarcinoma: suggestion for an effective screening strategy for these tumors
-
Koh Y, Kim DW, Kim TM, et al. Clinicopathologic characteristics and outcomes of patients with anaplastic lymphoma kinase-positive advanced pulmonary adenocarcinoma: suggestion for an effective screening strategy for these tumors. J Thorac Oncol. 2011;6(5):905-912.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.5
, pp. 905-912
-
-
Koh, Y.1
Kim, D.W.2
Kim, T.M.3
-
140
-
-
69349083935
-
Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population
-
Rodig SJ, Mino-Kenudson M, Dacic S, et al. Unique clinicopathologic features characterize ALK-rearranged lung adenocarcinoma in the western population. Clin Cancer Res. 2009;15(16):5216-5223.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.16
, pp. 5216-5223
-
-
Rodig, S.J.1
Mino-Kenudson, M.2
Dacic, S.3
-
141
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol. 2009;27(26):4247-4253.
-
(2009)
J Clin Oncol
, vol.27
, Issue.26
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
142
-
-
80053386829
-
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: A retrospective analysis
-
Shaw AT, Yeap BY, Solomon BJ, et al. Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis. Lancet Oncol. 2011;12(11):1004- 1012.
-
(2011)
Lancet Oncol
, vol.12
, Issue.11
, pp. 1004-1012
-
-
Shaw, A.T.1
Yeap, B.Y.2
Solomon, B.J.3
-
143
-
-
84858297956
-
The cost-effectiveness of screening lung cancer patients for targeted drug sensitivity markers
-
Atherly AJ, Camidge DR. The cost-effectiveness of screening lung cancer patients for targeted drug sensitivity markers. Br J Cancer. 2012;106(6):1100- 1106.
-
(2012)
Br J Cancer
, vol.106
, Issue.6
, pp. 1100-1106
-
-
Atherly, A.J.1
Camidge, D.R.2
-
144
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med. 2010;363(18):1693- 1703.
-
(2010)
N Engl J Med
, vol.363
, Issue.18
, pp. 1693-1703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
145
-
-
78650436429
-
Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer
-
Ou SH, Bazhenova L, Camidge DR, et al. Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer. J Thorac Oncol. 2010;5(12):2044-2046.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.12
, pp. 2044-2046
-
-
Ou, S.H.1
Bazhenova, L.2
Camidge, D.R.3
-
146
-
-
84856877692
-
The potential for crizotinib in non-small cell lung cancer: A perspective review
-
Bang YJ. The potential for crizotinib in non-small cell lung cancer: a perspective review. Ther Adv Med Oncol. 2011;3(6):279-291.
-
(2011)
Ther Adv Med Oncol
, vol.3
, Issue.6
, pp. 279-291
-
-
Bang, Y.J.1
-
147
-
-
84859124139
-
Crizotinib: A novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond
-
Ou SH. Crizotinib: a novel and first-in-class multitargeted tyrosine kinase inhibitor for the treatment of anaplastic lymphoma kinase rearranged non-small cell lung cancer and beyond. Drug Des Devel Ther. 2011;5:471-485.
-
(2011)
Drug Des Devel Ther
, vol.5
, pp. 471-485
-
-
Ou, S.H.1
-
148
-
-
84863950585
-
Management of crizotinib, A new individualized treatment
-
Fallet V, Toper C, Antoine M, Cadranel J, Wislez M. Management of crizotinib, a new individualized treatment. Bull Cancer. 2012;99(7-8):787-791.
-
(2012)
Bull Cancer
, vol.99
, Issue.7-8
, pp. 787-791
-
-
Fallet, V.1
Toper, C.2
Antoine, M.3
Cadranel, J.4
Wislez, M.5
-
149
-
-
84857735657
-
Drug approvals 2011: Focus on companion diagnostics
-
Goozner M. Drug approvals 2011: Focus on companion diagnostics. J Natl Cancer Inst. 2012;104(2):84-86.
-
(2012)
J Natl Cancer Inst
, vol.104
, Issue.2
, pp. 84-86
-
-
Goozner, M.1
-
150
-
-
84868312165
-
Treating ALK-positive lung cancer in the weeks after the FDA approval of crizotinib
-
(spec No. 2)
-
Pennell NA. Treating ALK-positive lung cancer in the weeks after the FDA approval of crizotinib. Am J Manag Care. 2012;18(5)(spec No. 2):SP84-SP87.
-
(2012)
Am J Manag Care
, vol.18
, Issue.5
-
-
Pennell, N.A.1
-
152
-
-
78049426513
-
EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors
-
Choi YL, Soda M, Yamashita Y, et al. EML4-ALK mutations in lung cancer that confer resistance to ALK inhibitors. N Engl J Med. 2010;363(18):1734-1739.
-
(2010)
N Engl J Med.
, vol.363
, Issue.18
, pp. 1734-1739
-
-
Choi, Y.L.1
Soda, M.2
Yamashita, Y.3
-
153
-
-
84856990335
-
Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer
-
Doebele RC, Pilling AB, Aisner DL, et al. Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. Clin Cancer Res. 2012;18(5):1472-1482.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.5
, pp. 1472-1482
-
-
Doebele, R.C.1
Pilling, A.B.2
Aisner, D.L.3
-
154
-
-
79956318797
-
Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK
-
Katayama R, Khan TM, Benes C, et al. Therapeutic strategies to overcome crizotinib resistance in non-small cell lung cancers harboring the fusion oncogene EML4-ALK. Proc Natl Acad Sci U S A. 2011;108(18):7535-7540.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.18
, pp. 7535-7540
-
-
Katayama, R.1
Khan, T.M.2
Benes, C.3
-
155
-
-
84856999699
-
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers
-
Katayama R, Shaw AT, Khan TM, et al. Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers. Sci Transl Med. 2012;4(120):120ra17.
-
(2012)
Sci Transl Med
, vol.4
, Issue.120
-
-
Katayama, R.1
Shaw, A.T.2
Khan, T.M.3
-
156
-
-
84856999699
-
Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers
-
120ra17
-
Katayama R, Shaw AT, Khan TM, et al. Mechanisms of acquired crizotinib resistance in ALK-rearranged lung cancers. Sci Transl Med. 2012;4(120):120ra17.
-
(2012)
Sci Transl Med
, vol.4
, Issue.120
-
-
Katayama, R.1
Shaw, A.T.2
Khan, T.M.3
-
157
-
-
84862513803
-
Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non-small cell lung cancer: A multicenter study of 774 patients
-
Navani N, Brown JM, Nankivell M, et al. Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non-small cell lung cancer: a multicenter study of 774 patients. Am J Respir Crit Care Med. 2012;185(12):1316-1322.
-
(2012)
Am J Respir Crit Care Med
, vol.185
, Issue.12
, pp. 1316-1322
-
-
Navani, N.1
Brown, J.M.2
Nankivell, M.3
-
158
-
-
79951769998
-
Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: High accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing
-
Rekhtman N, Brandt SM, Sigel CS, et al. Suitability of thoracic cytology for new therapeutic paradigms in non-small cell lung carcinoma: high accuracy of tumor subtyping and feasibility of EGFR and KRAS molecular testing. J Thorac Oncol. 2011;6(3):451-458.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.3
, pp. 451-458
-
-
Rekhtman, N.1
Brandt, S.M.2
Sigel, C.S.3
-
159
-
-
74749089695
-
Core needle lung biopsy specimens: Adequacy for EGFR and KRAS mutational analysis
-
Solomon SB, Zakowski MF, Pao W, et al. Core needle lung biopsy specimens: adequacy for EGFR and KRAS mutational analysis. AJR Am J Roentgenol. 2010;194(1):266-269.
-
(2010)
AJR Am J Roentgenol
, vol.194
, Issue.1
, pp. 266-269
-
-
Solomon, S.B.1
Zakowski, M.F.2
Pao, W.3
-
160
-
-
84863781238
-
Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma
-
Hasanovic A, Ang D, Moreira AL, Zakowski MF. Use of mutation specific antibodies to detect EGFR status in small biopsy and cytology specimens of lung adenocarcinoma. Lung Cancer. 2012;77(2):299-305.
-
(2012)
Lung Cancer
, vol.77
, Issue.2
, pp. 299-305
-
-
Hasanovic, A.1
Ang, D.2
Moreira, A.L.3
Zakowski, M.F.4
-
161
-
-
84865418815
-
Evaluation of EGFR mutation status in cytology specimens: An institutional experience
-
Aisner DL, Deshpande C, Baloch Z, et al. Evaluation of EGFR mutation status in cytology specimens: an institutional experience. Diagn Cytopathol. 2011.
-
(2011)
Diagn Cytopathol
-
-
Aisner, D.L.1
Deshpande, C.2
Baloch, Z.3
-
162
-
-
84855166390
-
Reliability of direct sequencing of EGFR: Comparison between cytological and histological samples from the same patient
-
Bruno P, Mariotta S, Ricci A, et al. Reliability of direct sequencing of EGFR: comparison between cytological and histological samples from the same patient. Anticancer Res. 2011;31(12):4207-4210.
-
(2011)
Anticancer Res
, vol.31
, Issue.12
, pp. 4207-4210
-
-
Bruno, P.1
Mariotta, S.2
Ricci, A.3
-
163
-
-
84856382169
-
EGFR mutation testing in nonsmall cell lung cancer patients by using cytology specimens: When the tissue is no longer the issue
-
Gil-Bazo I, Castanon E, Fusco JP. EGFR mutation testing in nonsmall cell lung cancer patients by using cytology specimens: when the tissue is no longer the issue. Cancer Cytopathol. 2011;119(5):354.
-
(2011)
Cancer Cytopathol
, vol.119
, Issue.5
, pp. 354
-
-
Gil-Bazo, I.1
Castanon, E.2
Fusco, J.P.3
-
164
-
-
84863777030
-
Detection of EML4-ALK fusion genes in a few cancer cells from transbronchial cytological specimens utilizing immediate cytology during bronchoscopy
-
Kanaji N, Bandoh S, Ishii T, et al. Detection of EML4-ALK fusion genes in a few cancer cells from transbronchial cytological specimens utilizing immediate cytology during bronchoscopy. Lung Cancer. 2012;77(2):293-298.
-
(2012)
Lung Cancer
, vol.77
, Issue.2
, pp. 293-298
-
-
Kanaji, N.1
Bandoh, S.2
Ishii, T.3
-
165
-
-
84863992604
-
The positive impact of cytological specimens for EGFR mutation testing in non-small cell lung cancer: A single South East Asian laboratory's analysis of 670 cases
-
Pang B, Matthias D, Ong CW, et al. The positive impact of cytological specimens for EGFR mutation testing in non-small cell lung cancer: a single South East Asian laboratory's analysis of 670 cases. Cytopathology. 2012;23(4): 229-236.
-
(2012)
Cytopathology
, vol.23
, Issue.4
, pp. 229-236
-
-
Pang, B.1
Matthias, D.2
Ong, C.W.3
-
166
-
-
83155188290
-
Use of CT-guided fine needle aspiration biopsy in epidermal growth factor receptor mutation analysis in patients with advanced lung cancer
-
Zhuang YP, Wang HY, Shi MQ, Zhang J, Feng Y. Use of CT-guided fine needle aspiration biopsy in epidermal growth factor receptor mutation analysis in patients with advanced lung cancer. Acta Radiol. 2011;52(10):1083-1087.
-
(2011)
Acta Radiol
, vol.52
, Issue.10
, pp. 1083-1087
-
-
Zhuang, Y.P.1
Wang, H.Y.2
Shi, M.Q.3
Zhang, J.4
Feng, Y.5
-
167
-
-
79956318148
-
Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer
-
Mino-Kenudson M, Mark EJ. Reflex testing for epidermal growth factor receptor mutation and anaplastic lymphoma kinase fluorescence in situ hybridization in non-small cell lung cancer. Arch Pathol Lab Med. 2011; 135(5):655-664.
-
(2011)
Arch Pathol Lab Med
, vol.135
, Issue.5
, pp. 655-664
-
-
Mino-Kenudson, M.1
Mark, E.J.2
-
168
-
-
84864621910
-
Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers
-
Cheung HW, Du J, Boehm JS, et al. Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in
-
(2011)
Cancer Discov
, vol.1
, Issue.7
, pp. 608-625
-
-
Cheung, H.W.1
Du, J.2
Boehm, J.S.3
-
169
-
-
77951643141
-
Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor
-
Ercan D, Zejnullahu K, Yonesaka K, et al. Amplification of EGFR T790M causes resistance to an irreversible EGFR inhibitor. Oncogene. 2010;29(16): 2346-2356.
-
(2010)
Oncogene
, vol.29
, Issue.16
, pp. 2346-2356
-
-
Ercan, D.1
Zejnullahu, K.2
Yonesaka, K.3
-
170
-
-
70349464846
-
Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway
-
Nguyen KS, Kobayashi S, Costa DB. Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. Clin Lung Cancer. 2009;10(4):281-289.
-
(2009)
Clin Lung Cancer
, vol.10
, Issue.4
, pp. 281-289
-
-
Nguyen, K.S.1
Kobayashi, S.2
Costa, D.B.3
-
171
-
-
84864402225
-
Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer
-
Zhang Z, Lee JC, Lin L, et al. Activation of the AXL kinase causes resistance to EGFR-targeted therapy in lung cancer. Nat Genet. 2012.
-
(2012)
Nat Genet
-
-
Zhang, Z.1
Lee, J.C.2
Lin, L.3
-
172
-
-
84863410315
-
EGFR-TKI resistant non-small cell lung cancer (NSCLC): New developments and implications for future treatment
-
Brugger W, Thomas M. EGFR-TKI resistant non-small cell lung cancer (NSCLC): new developments and implications for future treatment. Lung Cancer. 2012;77(1):2-8.
-
(2012)
Lung Cancer
, vol.7
, Issue.1
, pp. 2-8
-
-
Brugger, W.1
Thomas, M.2
-
173
-
-
84860461938
-
A new generation of EGFR tyrosine-kinase inhibitors in NSCLC
-
Hirsch FR, Bunn PA Jr. A new generation of EGFR tyrosine-kinase inhibitors in NSCLC. Lancet Oncol. 2012;13(5):442-443.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 442-443
-
-
Hirsch, F.R.1
Bunn Jr., P.A.2
-
174
-
-
79957857433
-
The BATTLE trial: Personalizing therapy for lung cancer
-
Kim ES, Herbst RS, Wistuba II, et al. The BATTLE trial: personalizing therapy for lung cancer. Cancer Discov. 2011;1(1):44-53.
-
(2011)
Cancer Discov
, vol.1
, Issue.1
, pp. 44-53
-
-
Kim, E.S.1
Herbst, R.S.2
Wistuba, I.I.3
-
175
-
-
84873998878
-
Targeted agents in the third-/fourth-line treatment of patients with advanced (stage III/IV) non-small cell lung cancer (NSCLC)
-
Langer CJ, Mok T, Postmus PE. Targeted agents in the third-/fourth-line treatment of patients with advanced (stage III/IV) non-small cell lung cancer (NSCLC). Cancer Treat Rev. 2012.
-
(2012)
Cancer Treat Rev
-
-
Langer, C.J.1
Mok, T.2
Postmus, P.E.3
-
176
-
-
77950586775
-
The role of irreversible EGFR inhibitors in the treatment of nonsmall cell lung cancer: Overcoming resistance to reversible EGFR inhibitors
-
Belani CP. The role of irreversible EGFR inhibitors in the treatment of nonsmall cell lung cancer: overcoming resistance to reversible EGFR inhibitors. Cancer Invest. 2010;28(4):413-423.
-
(2010)
Cancer Invest
, vol.28
, Issue.4
, pp. 413-423
-
-
Belani, C.P.1
-
177
-
-
77953362931
-
New strategies to overcome limitations of reversible EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer
-
Doebele RC, Oton AB, Peled N, Camidge DR, Bunn PA Jr. New strategies to overcome limitations of reversible EGFR tyrosine kinase inhibitor therapy in non-small cell lung cancer. Lung Cancer. 2010;69(1):1-12.
-
(2010)
Lung Cancer
, vol.69
, Issue.1
, pp. 1-12
-
-
Doebele, R.C.1
Oton, A.B.2
Peled, N.3
Camidge, D.R.4
Bunn Jr., P.A.5
-
178
-
-
79960986318
-
Strategies for overcoming resistance to EGFR family tyrosine kinase inhibitors
-
Giaccone G,Wang Y. Strategies for overcoming resistance to EGFR family tyrosine kinase inhibitors. Cancer Treat Rev. 2011;37(6):456-464.
-
(2011)
Cancer Treat Rev
, vol.37
, Issue.6
, pp. 456-464
-
-
Giaccone, G.1
Wang, Y.2
-
179
-
-
82355190618
-
The role of irreversible HER family inhibition in the treatment of patients with non-small cell lung cancer
-
Kwak E. The role of irreversible HER family inhibition in the treatment of patients with non-small cell lung cancer. Oncologist. 2011;16(11):1498-1507.
-
(2011)
Oncologist
, vol.16
, Issue.11
, pp. 1498-1507
-
-
Kwak, E.1
-
180
-
-
84859418112
-
The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor
-
Kim Y, Ko J, Cui Z, et al. The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor. Mol Cancer Ther. 2012;11(3):784-791.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.3
, pp. 784-791
-
-
Kim, Y.1
Ko, J.2
Cui, Z.3
-
181
-
-
84862785051
-
Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-lung 1): A phase 2b/3 randomised trial
-
Miller VA, Hirsh V, Cadranel J, et al. Afatinib versus placebo for patients with advanced, metastatic non-small-cell lung cancer after failure of erlotinib, gefitinib, or both, and one or two lines of chemotherapy (LUX-lung 1): a phase 2b/3 randomised trial. Lancet Oncol. 2012;13(5):528-538.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 528-538
-
-
Miller, V.A.1
Hirsh, V.2
Cadranel, J.3
-
182
-
-
84858669035
-
Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): A better mousetrap?: A review of the clinical evidence
-
Ou SH. Second-generation irreversible epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs): a better mousetrap?: a review of the clinical evidence. Crit Rev Oncol Hematol. 2012.
-
(2012)
Crit Rev Oncol Hematol
-
-
Ou, S.H.1
-
183
-
-
84866255620
-
Randomized phase II study of dacomitinib (PF-00299804), An irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced nonsmall- cell lung cancer
-
Ramalingam SS, Blackhall F, Krzakowski M, et al. Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced nonsmall- cell lung cancer. J Clin Oncol. 2012.
-
(2012)
J Clin Oncol
-
-
Ramalingam, S.S.1
Blackhall, F.2
Krzakowski, M.3
-
184
-
-
84862819699
-
Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-lung 2): A phase 2 trial
-
Yang JC, Shih JY, Su WC, et al. Afatinib for patients with lung adenocarcinoma and epidermal growth factor receptor mutations (LUX-lung 2): a phase 2 trial. Lancet Oncol. 2012;13(5):539-548.
-
(2012)
Lancet Oncol
, vol.13
, Issue.5
, pp. 539-548
-
-
Yang, J.C.1
Shih, J.Y.2
Su, W.C.3
-
185
-
-
79960110757
-
Afatinib (BIBW 2992) development in non-small-cell lung cancer
-
Hirsh V. Afatinib (BIBW 2992) development in non-small-cell lung cancer. Future Oncol. 2011;7(7):817-825.
-
(2011)
Future Oncol
, vol.7
, Issue.7
, pp. 817-825
-
-
Hirsh, V.1
-
186
-
-
79955853698
-
The LUX-lung clinical trial program of afatinib for nonsmall- cell lung cancer
-
Metro G, Crino L. The LUX-lung clinical trial program of afatinib for nonsmall- cell lung cancer. Expert Rev Anticancer Ther. 2011;11(5):673-682.
-
(2011)
Expert Rev Anticancer Ther
, vol.11
, Issue.5
, pp. 673-682
-
-
Metro, G.1
Crino, L.2
-
187
-
-
84859795661
-
Phase I study of continuous afatinib (BIBW 2992) in patients with advanced non-small cell lung cancer after prior chemotherapy/erlotinib/gefitinib (LUX-lung 4)
-
Murakami H, Tamura T, Takahashi T, et al. Phase I study of continuous afatinib (BIBW 2992) in patients with advanced non-small cell lung cancer after prior chemotherapy/erlotinib/gefitinib (LUX-lung 4). Cancer Chemother Pharmacol. 2012;69(4):891-899.
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, Issue.4
, pp. 891-899
-
-
Murakami, H.1
Tamura, T.2
Takahashi, T.3
-
188
-
-
37549061078
-
PF00299804, An irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib
-
Engelman JA, Zejnullahu K, Gale CM, et al. PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib. Cancer Res. 2007;67(24):11924-11932.
-
(2007)
Cancer Res
, vol.67
, Issue.24
, pp. 11924-11932
-
-
Engelman, J.A.1
Zejnullahu, K.2
Gale, C.M.3
-
189
-
-
78049451972
-
Personalizing therapy in an epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer using PF-00299804 and trastuzumab
-
Kelly RJ, Carter C, Giaccone G. Personalizing therapy in an epidermal growth factor receptor-tyrosine kinase inhibitor-resistant non-small-cell lung cancer using PF-00299804 and trastuzumab. J Clin Oncol. 2010;28(28):e507-10.
-
(2010)
J Clin Oncol
, vol.28
, Issue.28
-
-
Kelly, R.J.1
Carter, C.2
Giaccone, G.3
-
190
-
-
84858342654
-
EGFR-mutant lung adenocarcinomas treated first-line with the novel EGFR inhibitor, XL647, can subsequently retain moderate sensitivity to erlotinib
-
Chmielecki J, Pietanza MC, Aftab D, et al. EGFR-mutant lung adenocarcinomas treated first-line with the novel EGFR inhibitor, XL647, can subsequently retain moderate sensitivity to erlotinib. J Thorac Oncol. 2012;7(2): 434-442.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.2
, pp. 434-442
-
-
Chmielecki, J.1
Pietanza, M.C.2
Aftab, D.3
-
191
-
-
84862115744
-
Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer
-
Pietanza MC, Gadgeel SM, Dowlati A, et al. Phase II study of the multitargeted tyrosine kinase inhibitor XL647 in patients with non-small-cell lung cancer. J Thorac Oncol. 2012;7(5):856-865.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.5
, pp. 856-865
-
-
Pietanza, M.C.1
Gadgeel, S.M.2
Dowlati, A.3
-
192
-
-
84655160812
-
XL647-A multitargeted tyrosine kinase inhibitor: Results of a phase II study in subjects with non-small cell lung cancer who have progressed after responding to treatment with either gefitinib or erlotinib
-
Pietanza MC, Lynch TJ Jr, Lara PN Jr, et al. XL647-a multitargeted tyrosine kinase inhibitor: results of a phase II study in subjects with non-small cell lung cancer who have progressed after responding to treatment with either gefitinib or erlotinib. J Thorac Oncol. 2012;7(1):219-226.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.1
, pp. 219-226
-
-
Pietanza, M.C.1
Lynch Jr., T.J.2
Lara Jr., P.N.3
-
193
-
-
79952259564
-
Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay
-
Arcila ME, Oxnard GR, Nafa K, et al. Rebiopsy of lung cancer patients with acquired resistance to EGFR inhibitors and enhanced detection of the T790M mutation using a locked nucleic acid-based assay. Clin Cancer Res. 2011; 17(5):1169-1180.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.5
, pp. 1169-1180
-
-
Arcila, M.E.1
Oxnard, G.R.2
Nafa, K.3
-
194
-
-
79952711946
-
Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: Distinct natural history of patients with tumors harboring the T790M mutation
-
Oxnard GR, Arcila ME, Sima CS, et al. Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation. Clin Cancer Res. 2011; 17(6):1616-1622.
-
(2011)
Clin Cancer Res
, vol.17
, Issue.6
, pp. 1616-1622
-
-
Oxnard, G.R.1
Arcila, M.E.2
Sima, C.S.3
-
196
-
-
84863778954
-
Prognostic factors in patients with advanced non-small cell lung cancer: Data from the phase III FLEX study
-
Pirker R, Pereira JR, Szczesna A, et al. Prognostic factors in patients with advanced non-small cell lung cancer: data from the phase III FLEX study. Lung Cancer. 2012;77(2):376-382.
-
(2012)
Lung Cancer
, vol.77
, Issue.2
, pp. 376-382
-
-
Pirker, R.1
Pereira, J.R.2
Szczesna, A.3
-
197
-
-
84855311144
-
EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: Analysis of data from the phase 3 FLEX study
-
Pirker R, Pereira JR, von Pawel J, et al. EGFR expression as a predictor of survival for first-line chemotherapy plus cetuximab in patients with advanced non-small-cell lung cancer: analysis of data from the phase 3 FLEX study. Lancet Oncol. 2012;13(1):33-42.
-
(2012)
Lancet Oncol
, vol.13
, Issue.1
, pp. 33-42
-
-
Pirker, R.1
Pereira, J.R.2
Von Pawel, J.3
-
198
-
-
79960894047
-
Molecular biomarkers in non-small-cell lung cancer: A retrospective analysis of data from the phase 3 FLEX study
-
O'Byrne KJ, Gatzemeier U, Bondarenko I, et al. Molecular biomarkers in non-small-cell lung cancer: a retrospective analysis of data from the phase 3 FLEX study. Lancet Oncol. 2011;12(8):795-805.
-
(2011)
Lancet Oncol
, vol.12
, Issue.8
, pp. 795-805
-
-
O'Byrne, K.J.1
Gatzemeier, U.2
Bondarenko, I.3
-
199
-
-
78149240941
-
Phase II selection design trial of concurrent chemotherapy and cetuximab versus chemotherapy followed by cetuximab in advanced-stage non-small-cell lung cancer: Southwest Oncology Group study S0342
-
Herbst RS, Kelly K, Chansky K, et al. Phase II selection design trial of concurrent chemotherapy and cetuximab versus chemotherapy followed by cetuximab in advanced-stage non-small-cell lung cancer: Southwest Oncology Group study S0342. J Clin Oncol. 2010;28(31):4747-4754.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4747-4754
-
-
Herbst, R.S.1
Kelly, K.2
Chansky, K.3
-
200
-
-
84864489915
-
Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819
-
published online ahead of print May 16, 2012
-
Redman MW, Crowley JJ, Herbst RS, Hirsch FR, Gandara DR. Design of a phase III clinical trial with prospective biomarker validation: SWOG S0819 [published online ahead of print May 16, 2012]. Clin Cancer Res. 2012;18(15): 4004-4012.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.15
, pp. 4004-4012
-
-
Redman, M.W.1
Crowley, J.J.2
Herbst, R.S.3
Hirsch, F.R.4
Gandara, D.R.5
-
201
-
-
84857985225
-
RET ROS1 and ALK fusions in lung cancer
-
Takeuchi K, Soda M, Togashi Y, et al. RET, ROS1 and ALK fusions in lung cancer. Nat Med. 2012;18(3):378-381.
-
(2012)
Nat Med
, vol.18
, Issue.3
, pp. 378-381
-
-
Takeuchi, K.1
Soda, M.2
Togashi, Y.3
-
202
-
-
84862846839
-
Preclinical rationale for use of the clinically available multitargeted tyrosine kinase inhibitor crizotinib in ROS1-translocated lung cancer
-
Yasuda H, de Figueiredo-Pontes LL, Kobayashi S, Costa DB. Preclinical rationale for use of the clinically available multitargeted tyrosine kinase inhibitor crizotinib in ROS1-translocated lung cancer. J Thorac Oncol. 2012;7(7):1086- 1090.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.7
, pp. 1086-1090
-
-
Yasuda, H.1
De Figueiredo-Pontes, L.L.2
Kobayashi, S.3
Costa, D.B.4
-
203
-
-
84861313207
-
Crizotinib in the treatment of non-small-cell lung cancer
-
Forde PM, Rudin CM. Crizotinib in the treatment of non-small-cell lung cancer. Expert Opin Pharmacother. 2012;13(8):1195-1201.
-
(2012)
Expert Opin Pharmacother
, vol.13
, Issue.8
, pp. 1195-1201
-
-
Forde, P.M.1
Rudin, C.M.2
-
204
-
-
84863338079
-
ROS1 rearrangements define a unique molecular class of lung cancers
-
Bergethon K, Shaw AT, Ou SH, et al. ROS1 rearrangements define a unique molecular class of lung cancers. J Clin Oncol. 2012;30(8):863-870.
-
(2012)
J Clin Oncol
, vol.30
, Issue.8
, pp. 863-870
-
-
Bergethon, K.1
Shaw, A.T.2
Ou, S.H.3
-
205
-
-
84858815363
-
ROS1 rearrangements in lung cancer: A new genomic subset of lung adenocarcinoma
-
Janne PA, Meyerson M. ROS1 rearrangements in lung cancer: a new genomic subset of lung adenocarcinoma. J Clin Oncol. 2012;30(8):878-879.
-
(2012)
J Clin Oncol
, vol.30
, Issue.8
, pp. 878-879
-
-
Janne, P.A.1
Meyerson, M.2
-
206
-
-
84859794344
-
ROS1 as a 'druggable' receptor tyrosine kinase: Lessons learned from inhibiting the ALK pathway
-
Ou SH, Tan J, Yen Y, Soo RA. ROS1 as a 'druggable' receptor tyrosine kinase: lessons learned from inhibiting the ALK pathway. Expert Rev Anticancer Ther. 2012;12(4):447-456.
-
(2012)
Expert Rev Anticancer Ther
, vol.12
, Issue.4
, pp. 447-456
-
-
Ou, S.H.1
Tan, J.2
Yen, Y.3
Soo, R.A.4
-
207
-
-
84865089246
-
Analysis of receptor tyrosine kinase ROS1 positive tumors in non-small cell lung cancer: Identification of a FIG-ROS1 fusion
-
published online ahead of print June 1, 2012
-
Rimkunas VM, Crosby K, Kelly M, et al. Analysis of receptor tyrosine kinase ROS1 positive tumors in non-small cell lung cancer: Identification of a FIG-ROS1 fusion [published online ahead of print June 1, 2012]. Clin Cancer Res. 2012;18(16):4449-4457.
-
(2012)
Clin Cancer Res
, vol.18
, Issue.16
, pp. 4449-4457
-
-
Rimkunas, V.M.1
Crosby, K.2
Kelly, M.3
-
208
-
-
84866450872
-
KIF5B/RET fusion gene in surgicallytreated adenocarcinoma of the lung
-
published online ahead of print July 13, 2012, doi:10.3892/or.2012
-
Yokota K, Sasaki H, Okuda K, et al. KIF5B/RET fusion gene in surgicallytreated adenocarcinoma of the lung [published online ahead of print July 13, 2012]. Oncol Rep. doi:10.3892/or.2012.
-
Oncol Rep
-
-
Yokota, K.1
Sasaki, H.2
Okuda, K.3
-
209
-
-
84862776857
-
Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies
-
Lipson D, Capelletti M, Yelensky R, et al. Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies. Nat Med. 2012;18(3): 382-384.
-
(2012)
Nat Med
, vol.18
, Issue.3
, pp. 382-384
-
-
Lipson, D.1
Capelletti, M.2
Yelensky, R.3
-
210
-
-
84862812241
-
Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers
-
Li F, Feng Y, Fang R, et al. Identification of RET gene fusion by exon array analyses in "pan-negative" lung cancer from never smokers. Cell Res. 2012;22(5): 928-931.
-
(2012)
Cell Res
, vol.22
, Issue.5
, pp. 928-931
-
-
Li, F.1
Feng, Y.2
Fang, R.3
-
211
-
-
84857929267
-
KIF5B-RET fusions in lung adenocarcinoma
-
Kohno T, Ichikawa H, Totoki Y, et al. KIF5B-RET fusions in lung adenocarcinoma. Nat Med. 2012;18(3):375-377.
-
(2012)
Nat Med
, vol.18
, Issue.3
, pp. 375-377
-
-
Kohno, T.1
Ichikawa, H.2
Totoki, Y.3
-
212
-
-
84863230117
-
A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing
-
Ju YS, Lee WC, Shin JY, et al. A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing. Genome Res. 2012;22(3):436-445.
-
(2012)
Genome Res
, vol.22
, Issue.3
, pp. 436-445
-
-
Ju, Y.S.1
Lee, W.C.2
Shin, J.Y.3
-
213
-
-
84997909291
-
C-MET as a potential therapeutic target and biomarker in cancer
-
Sierra JR, Tsao MS. c-MET as a potential therapeutic target and biomarker in cancer. Ther Adv Med Oncol. 2011;3(1 suppl):S21-S35.
-
(2012)
Ther Adv Med Oncol
, vol.3
, Issue.1 SUPPL..
-
-
Sierra, J.R.1
Tsao, M.S.2
-
214
-
-
84865506979
-
Rationale and design of MARQUEE: A phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-small-cell lung cancer
-
published online ahead of print March 21, 2012
-
Scagliotti GV, Novello S, Schiller JH, et al. c [published online ahead of print March 21, 2012]. Clin Lung Cancer. 2012;13:391-395.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 391-395
-
-
Scagliotti, G.V.1
Novello, S.2
Schiller, J.H.3
-
215
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated nonsmall- cell lung cancer
-
Sequist LV, von Pawel J, Garmey EG, et al. Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated nonsmall- cell lung cancer. J Clin Oncol. 2011;29(24):3307-3315.
-
(2011)
J Clin Oncol
, vol.29
, Issue.24
, pp. 3307-3315
-
-
Sequist, L.V.1
Von Pawel, J.2
Garmey, E.G.3
-
216
-
-
40349106029
-
The potential role of mTOR inhibitors in non-small cell lung cancer
-
Gridelli C, Maione P, Rossi A. The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist. 2008;13(2):139-147.
-
(2008)
Oncologist
, vol.13
, Issue.2
, pp. 139-147
-
-
Gridelli, C.1
Maione, P.2
Rossi, A.3
-
217
-
-
79956078123
-
The dual PI3K/mTOR inhibitor BEZ235 is effective in lung cancer cell lines
-
Herrera VA, Zeindl-Eberhart E, Jung A, Huber RM, Bergner A. The dual PI3K/mTOR inhibitor BEZ235 is effective in lung cancer cell lines. Anticancer Res. 2011;31(3):849-854.
-
(2011)
Anticancer Res
, vol.31
, Issue.3
, pp. 849-854
-
-
Herrera, V.A.1
Zeindl-Eberhart, E.2
Jung, A.3
Huber, R.M.4
Bergner, A.5
-
218
-
-
79959560113
-
Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression
-
Kim YS, Jin HO, Seo SK, et al. Sorafenib induces apoptotic cell death in human non-small cell lung cancer cells by down-regulating mammalian target of rapamycin (mTOR)-dependent survivin expression. Biochem Pharmacol. 2011; 82(3):216-226.
-
(2011)
Biochem Pharmacol
, vol.82
, Issue.3
, pp. 216-226
-
-
Kim, Y.S.1
Jin, H.O.2
Seo, S.K.3
-
219
-
-
84863832579
-
Development of PI3K/AKT/mTOR pathway inhibitors and their application in personalized therapy for non-small-cell lung cancer
-
Papadimitrakopoulou V. Development of PI3K/AKT/mTOR pathway inhibitors and their application in personalized therapy for non-small-cell lung cancer. J Thorac Oncol. 2012.
-
(2012)
J Thorac Oncol
-
-
Papadimitrakopoulou, V.1
-
220
-
-
77956848562
-
Phase 1 and pharmacokinetic study of everolimus, A mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer
-
Ramalingam SS, Harvey RD, Saba N, et al. Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer. Cancer. 2010; 116(16):3903-3909.
-
(2010)
Cancer
, vol.116
, Issue.16
, pp. 3903-3909
-
-
Ramalingam, S.S.1
Harvey, R.D.2
Saba, N.3
-
221
-
-
84862133526
-
Brief Report: A Phase II "window-of-opportunity" frontline study of the mTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study
-
Reungwetwattana T, Molina JR, Mandrekar SJ, et al. Brief report: A phase II "window-of-opportunity" frontline study of the mTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study. J Thorac Oncol. 2012;7(5):919-922.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.5
, pp. 919-922
-
-
Reungwetwattana, T.1
Molina, J.R.2
Mandrekar, S.J.3
-
222
-
-
70349637311
-
Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors
-
Soria JC, Shepherd FA, Douillard JY, et al. Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors. Ann Oncol. 2009;20(10): 1674-1681.
-
(2009)
Ann Oncol
, vol.20
, Issue.10
, pp. 1674-1681
-
-
Soria, J.C.1
Shepherd, F.A.2
Douillard, J.Y.3
-
223
-
-
81755184151
-
Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: A phase I study using a novel, adaptive Bayesian dose-escalation model
-
Vansteenkiste J, Solomon B, Boyer M, et al. Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: a phase I study using a novel, adaptive Bayesian dose-escalation model. J Thorac Oncol. 2011;6(12):2120-2129.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.12
, pp. 2120-2129
-
-
Vansteenkiste, J.1
Solomon, B.2
Boyer, M.3
-
224
-
-
26844545448
-
Overcoming cisplatin resistance by mTOR inhibitor in lung cancer
-
Wu C, Wangpaichitr M, Feun L, et al. Overcoming cisplatin resistance by mTOR inhibitor in lung cancer. Mol Cancer. 2005;4(1):25.
-
(2005)
Mol Cancer
, vol.4
, Issue.1
, pp. 25
-
-
Wu, C.1
Wangpaichitr, M.2
Feun, L.3
-
225
-
-
79958816470
-
The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo
-
Xu CX, Li Y, Yue P, et al. The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo. PLoS One. 2011;6(6):e20899.
-
(2011)
PLoS One
, vol.6
, Issue.6
-
-
Xu, C.X.1
Li, Y.2
Yue, P.3
-
226
-
-
84857136594
-
Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells
-
Zito CR, Jilaveanu LB, Anagnostou V, et al. Multi-level targeting of the phosphatidylinositol-3-kinase pathway in non-small cell lung cancer cells. PLoS One. 2012;7(2):e31331.
-
(2012)
PLoS One
, vol.7
, Issue.2
-
-
Zito, C.R.1
Jilaveanu, L.B.2
Anagnostou, V.3
-
227
-
-
84862907761
-
The novel dual PI3K/mTOR inhibitor GDC-0941 synergizes with the MEK inhibitor U0126 in non-small cell lung cancer cells
-
Zou ZQ, Zhang LN, Wang F, Bellenger J, Shen YZ, Zhang XH. The novel dual PI3K/mTOR inhibitor GDC-0941 synergizes with the MEK inhibitor U0126 in non-small cell lung cancer cells. Mol Med Report. 2012;5(2):503-508.
-
(2012)
Mol Med Report
, vol.5
, Issue.2
, pp. 503-508
-
-
Zou, Z.Q.1
Zhang, L.N.2
Wang, F.3
Bellenger, J.4
Shen, Y.Z.5
Zhang, X.H.6
-
228
-
-
0035559068
-
Advances in systemic therapy of small cell cancer of the lung
-
Daniels GA, Adjei AA. Advances in systemic therapy of small cell cancer of the lung. Expert Rev Anticancer Ther. 2001;1(2):211-221.
-
(2001)
Expert Rev Anticancer Ther
, vol.1
, Issue.2
, pp. 211-221
-
-
Daniels, G.A.1
Adjei, A.A.2
-
229
-
-
35848959875
-
A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage smallcell lung cancer who have responding or stable disease after induction chemotherapy: A trial of the Eastern Cooperative Oncology Group (E1500)
-
Pandya KJ, Dahlberg S, Hidalgo M, et al. A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage smallcell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500). J Thorac Oncol. 2007;2(11):1036-1041.
-
(2007)
J Thorac Oncol
, vol.2
, Issue.11
, pp. 1036-1041
-
-
Pandya, K.J.1
Dahlberg, S.2
Hidalgo, M.3
-
230
-
-
77955980679
-
Dual inhibition of EGFR and mTOR pathways in small cell lung cancer
-
Schmid K, Bago-Horvath Z, Berger W, et al. Dual inhibition of EGFR and mTOR pathways in small cell lung cancer. Br J Cancer. 2010;103(5):622-628.
-
(2010)
Br J Cancer
, vol.103
, Issue.5
, pp. 622-628
-
-
Schmid, K.1
Bago-Horvath, Z.2
Berger, W.3
-
232
-
-
78650403140
-
Phase II study of everolimus (RAD001) in previously treated small cell lung cancer
-
Tarhini A, Kotsakis A, Gooding W, et al. Phase II study of everolimus (RAD001) in previously treated small cell lung cancer. Clin Cancer Res. 2010; 16(23):5900-5907.
-
(2012)
Clin Cancer Res
, vol.16
, Issue.23
, pp. 5900-5907
-
-
Tarhini, A.1
Kotsakis, A.2
Gooding, W.3
-
233
-
-
34548710844
-
Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: Possible role for chemotherapeutic intervention
-
Achcar Rde O, Cagle PT, Jagirdar J. Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: possible role for chemotherapeutic intervention. Arch Pathol Lab Med. 2007;131(9):1350-1360.
-
(2007)
Arch Pathol Lab Med
, vol.131
, Issue.9
, pp. 1350-1360
-
-
Achcar Rde, O.1
Cagle, P.T.2
Jagirdar, J.3
-
234
-
-
84862796550
-
Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells
-
Liu X, Guo W, Wu S, et al. Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells. Biochem Pharmacol. 2012;83(10):1456-1464.
-
(2012)
Biochem Pharmacol
, vol.83
, Issue.10
, pp. 1456-1464
-
-
Liu, X.1
Guo, W.2
Wu, S.3
-
235
-
-
84857792454
-
Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules
-
Shimokawa T, Seike M, Soeno C, et al. Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules. Br J Cancer. 2012;106(5):867-875.
-
(2012)
Br J Cancer
, vol.106
, Issue.5
, pp. 867-875
-
-
Shimokawa, T.1
Seike, M.2
Soeno, C.3
-
236
-
-
84862193781
-
Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts
-
Zhang X, Yue P, Page BD, et al. Orally bioavailable small-molecule inhibitor of transcription factor Stat3 regresses human breast and lung cancer xenografts. Proc Natl Acad Sci U S A. 2012;109(24):9623-9628.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.24
, pp. 9623-9628
-
-
Zhang, X.1
Yue, P.2
Page, B.D.3
-
237
-
-
79951927432
-
The use of single-agent dasatinib in molecularly unselected non-small-cell lung cancer patients
-
Kruser TJ, Traynor AM, Wheeler DL. The use of single-agent dasatinib in molecularly unselected non-small-cell lung cancer patients. Expert Opin Investig Drugs. 2011;20(2):305-307.
-
(2012)
Expert Opin Investig Drugs
, vol.20
, Issue.2
, pp. 305-307
-
-
Kruser, T.J.1
Traynor, A.M.2
Wheeler, D.L.3
-
238
-
-
79958080372
-
Phase II trial of dasatinib for patients with acquired resistance to treatment with the epidermal growth factor receptor tyrosine kinase inhibitors erlotinib or gefitinib
-
Johnson ML, Riely GJ, Rizvi NA, et al. Phase II trial of dasatinib for patients with acquired resistance to treatment with the epidermal growth factor receptor tyrosine kinase inhibitors erlotinib or gefitinib. J Thorac Oncol. 2011; 6(6):1128-1131.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.6
, pp. 1128-1131
-
-
Johnson, M.L.1
Riely, G.J.2
Rizvi, N.A.3
-
239
-
-
78049495513
-
Phase II study of dasatinib in patients with advanced non-small-cell lung cancer
-
Johnson FM, Bekele BN, Feng L, et al. Phase II study of dasatinib in patients with advanced non-small-cell lung cancer. J Clin Oncol. 2010;28(30): 4609-4615.
-
(2010)
J Clin Oncol
, vol.28
, Issue.30
, pp. 4609-4615
-
-
Johnson, F.M.1
Bekele, B.N.2
Feng, L.3
-
240
-
-
44649143914
-
K-ras as a target for lung cancer therapy
-
Adjei AA. K-ras as a target for lung cancer therapy. J Thorac Oncol. 2008; 3(6)(suppl 2):S160-S163.
-
(2008)
J Thorac Oncol
, vol.3
, Issue.6 SUPPL. 2
-
-
Adjei, A.A.1
-
241
-
-
84856915008
-
Combined effect of ALK and MEK inhibitors in EML4-ALK-positive non-small-cell lung cancer cells
-
Tanizaki J, Okamoto I, Takezawa K, et al. Combined effect of ALK and MEK inhibitors in EML4-ALK-positive non-small-cell lung cancer cells. Br J Cancer. 2012;106(4):763-767.
-
(2012)
Br J Cancer
, vol.106
, Issue.4
, pp. 763-767
-
-
Tanizaki, J.1
Okamoto, I.2
Takezawa, K.3
-
242
-
-
79952457258
-
MEK/MAPK inhibitors
-
Dy G. MEK/MAPK inhibitors. J Thorac Oncol. 2010;5(12)(suppl 6):S474- S475.
-
(2010)
J Thorac Oncol
, vol.5
, Issue.12 SUPPL. 6
-
-
Dy, G.1
-
243
-
-
77951016969
-
A phase II study of PD-0325901, an oral MEK inhibitor, in previously treated patients with advanced non-small cell lung cancer
-
Haura EB, Ricart AD, Larson TG, et al. A phase II study of PD-0325901, an oral MEK inhibitor, in previously treated patients with advanced non-small cell lung cancer. Clin Cancer Res. 2010;16(8):2450-2457.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.8
, pp. 2450-2457
-
-
Haura, E.B.1
Ricart, A.D.2
Larson, T.G.3
-
245
-
-
84862095836
-
Personalized pathway enrichment map of putative cancer genes from next generation sequencing data
-
Jia P, Zhao Z. Personalized pathway enrichment map of putative cancer genes from next generation sequencing data. PLoS One. 2012;7(5):e37595.
-
(2012)
PLoS One
, vol.7
, Issue.5
-
-
Jia, P.1
Zhao, Z.2
-
246
-
-
84870899165
-
Deep sequence analysis of nonsmall cell lung cancer: Integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations
-
Kalari KR, Rossell D, Necela BM, et al. Deep sequence analysis of nonsmall cell lung cancer: integrated analysis of gene expression, alternative splicing, and single nucleotide variations in lung adenocarcinomas with and without oncogenic KRAS mutations. Front Oncol. 2012;2:12.
-
(2012)
Front Oncol
, vol.2
, pp. 12
-
-
Kalari, K.R.1
Rossell, D.2
Necela, B.M.3
-
247
-
-
84864408769
-
Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: Potential clinical implications
-
Marchetti A, Del Grammastro M, Filice G, et al. Complex mutations & subpopulations of deletions at exon 19 of EGFR in NSCLC revealed by next generation sequencing: potential clinical implications. PLoS One. 2012;7(7): e42164.
-
(2012)
PLoS One
, vol.7
, Issue.7
-
-
Marchetti, A.1
Del Grammastro, M.2
Filice, G.3
-
248
-
-
84861302770
-
Screening for germline EGFR T790M mutations through lung cancer genotyping
-
Oxnard GR, Miller VA, Robson ME, et al. Screening for germline EGFR T790M mutations through lung cancer genotyping. J Thorac Oncol. 2012;7(6): 1049-1052.
-
(2012)
J Thorac Oncol
, vol.7
, Issue.6
, pp. 1049-1052
-
-
Oxnard, G.R.1
Miller, V.A.2
Robson, M.E.3
-
249
-
-
84858439267
-
Recent advances in pathway-targeted cancer drug therapies emerging from cancer genome analysis
-
Yauch RL, Settleman J. Recent advances in pathway-targeted cancer drug therapies emerging from cancer genome analysis. Curr Opin Genet Dev. 2012; 22(1):45-49.
-
Curr Opin Genet Dev
, vol.22
, Issue.1
, pp. 45-49
-
-
Yauch, R.L.1
Settleman, J.2
-
250
-
-
67650441507
-
Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas
-
Boland JM, Erdogan S, Vasmatzis G, et al. Anaplastic lymphoma kinase immunoreactivity correlates with ALK gene rearrangement and transcriptional up-regulation in non-small cell lung carcinomas. Hum Pathol. 2009;40(8):1152- 1158.
-
(2009)
Hum Pathol
, vol.40
, Issue.8
, pp. 1152-1158
-
-
Boland, J.M.1
Erdogan, S.2
Vasmatzis, G.3
-
251
-
-
77649091118
-
A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry
-
Mino-Kenudson M, Chirieac LR, Law K, et al. A novel, highly sensitive antibody allows for the routine detection of ALK-rearranged lung adenocarcinomas by standard immunohistochemistry. Clin Cancer Res. 2010;16(5):1561- 1571.
-
(2010)
Clin Cancer Res
, vol.16
, Issue.5
, pp. 1561-1571
-
-
Mino-Kenudson, M.1
Chirieac, L.R.2
Law, K.3
-
252
-
-
79951774364
-
Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH
-
Yi ES, Boland JM, Maleszewski JJ, et al. Correlation of IHC and FISH for ALK gene rearrangement in non-small cell lung carcinoma: IHC score algorithm for FISH. J Thorac Oncol. 2011;6(3):459-465.
-
(2011)
J Thorac Oncol
, vol.6
, Issue.3
, pp. 459-465
-
-
Yi, E.S.1
Boland, J.M.2
Maleszewski, J.J.3
-
253
-
-
77649140830
-
Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR
-
Brevet M, Arcila M, Ladanyi M. Assessment of EGFR mutation status in lung adenocarcinoma by immunohistochemistry using antibodies specific to the two major forms of mutant EGFR. J Mol Diagn. 2010;12(2):169-176.
-
(2012)
J Mol Diagn
, vol.12
, Issue.2
, pp. 169-176
-
-
Brevet, M.1
Arcila, M.2
Ladanyi, M.3
-
254
-
-
65649128973
-
Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer
-
Yu J, Kane S, Wu J, et al. Mutation-specific antibodies for the detection of EGFR mutations in non-small-cell lung cancer. Clin Cancer Res. 2009;15(9): 3023-3028.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.9
, pp. 3023-3028
-
-
Yu, J.1
Kane, S.2
Wu, J.3
|