-
1
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al., Gefitinib or carboplatin- paclitaxel in pulmonary adenocarcinoma. New England J Med 2009; 361: 947-57.
-
(2009)
New England J Med
, vol.361
, pp. 947-957
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
2
-
-
80053561215
-
Erlotinib versus chemotherapy (CT) in advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: Interim results of the European Erlotinib Versus Chemotherapy (EURTAC) phase III randomized trial
-
suppl; abstract 7503.
-
Rosell R, Gervais R, Vergnenegre A, et al., Erlotinib versus chemotherapy (CT) in advanced non-small cell lung cancer (NSCLC) patients (p) with epidermal growth factor receptor (EGFR) mutations: Interim results of the European Erlotinib Versus Chemotherapy (EURTAC) phase III randomized trial. J Clin Oncol 2011; 29: suppl; abstract 7503.
-
(2011)
J Clin Oncol
, vol.29
-
-
Rosell, R.1
Gervais, R.2
Vergnenegre, A.3
-
3
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
DOI 10.1056/NEJMoa050753
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, et al., Erlotinib in previously treated non-small-cell lung cancer. New England J Med 2005; 353: 123-32. (Pubitemid 41058344)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Pereira, J.R.2
Ciuleanu, T.3
Eng, H.T.4
Hirsh, V.5
Thongprasert, S.6
Campos, D.7
Maoleekoonpiroj, S.8
Smylie, M.9
Martins, R.10
Van Kooten, M.11
Dediu, M.12
Findlay, B.13
Tu, D.14
Johnston, D.15
Bezjak, A.16
Clark, G.17
Santabarbara, P.18
Seymour, L.19
-
4
-
-
15744372810
-
KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib
-
Pao W, Wang TY, Riely GJ, et al., KRAS mutations and primary resistance of lung adenocarcinomas to gefitinib or erlotinib. PLoS Med 2005; 2: e17.
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Wang, T.Y.2
Riely, G.J.3
-
5
-
-
10844231985
-
Mutations of the epidermal growth factor receptor gene in lung cancer: Biological and clinical implications
-
DOI 10.1158/0008-5472.CAN-04-2818
-
Kosaka T, Yatabe Y, Endoh H, et al., Mutations of the epidermal growth factor receptor gene in lung cancer: biological and clinical implications. Cancer Res 2004; 64: 8919-23. (Pubitemid 39665498)
-
(2004)
Cancer Research
, vol.64
, Issue.24
, pp. 8919-8923
-
-
Kosaka, T.1
Yatabe, Y.2
Endoh, H.3
Kuwano, H.4
Takahashi, T.5
Mitsudomi, T.6
-
6
-
-
20044364940
-
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers
-
DOI 10.1093/jnci/dji055
-
Shigematsu H, Lin L, Takahashi T, et al., Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J National Cancer Inst 2005; 97: 339-46. (Pubitemid 40425952)
-
(2005)
Journal of the National Cancer Institute
, vol.97
, Issue.5
, pp. 339-346
-
-
Shigematsu, H.1
Lin, L.2
Takahashi, T.3
Nomura, M.4
Suzuki, M.5
Wistuba, I.I.6
Fong, K.M.7
Lee, H.8
Toyooka, S.9
Shimizu, N.10
Fujisawa, T.11
Feng, Z.12
Roth, J.A.13
Herz, J.14
Minna, J.D.15
Gazdar, A.F.16
-
7
-
-
28844501639
-
Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers
-
DOI 10.1002/ijc.21496
-
Shigematsu H, Gazdar AF,. Somatic mutations of epidermal growth factor receptor signaling pathway in lung cancers. Inter J cancer J Inter du Cancer 2006; 118: 257-62. (Pubitemid 41779062)
-
(2006)
International Journal of Cancer
, vol.118
, Issue.2
, pp. 257-262
-
-
Shigematsu, H.1
Gazdar, A.F.2
-
8
-
-
80052892102
-
Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR
-
Santis G, Angell R, Nickless G, et al., Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR. PLoS ONE 2011; 6: e25191.
-
(2011)
PLoS ONE
, vol.6
-
-
Santis, G.1
Angell, R.2
Nickless, G.3
-
10
-
-
43249116705
-
Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing
-
DOI 10.1038/nm1708, PII NM1708
-
Li J, Wang L, Mamon H, et al., Replacing PCR with COLD-PCR enriches variant DNA sequences and redefines the sensitivity of genetic testing. Nat Med 2008; 14: 579-84. (Pubitemid 351655208)
-
(2008)
Nature Medicine
, vol.14
, Issue.5
, pp. 579-584
-
-
Li, J.1
Wang, L.2
Mamon, H.3
Kulke, M.H.4
Berbeco, R.5
Makrigiorgos, G.M.6
-
11
-
-
47949114668
-
Detection of mutations in EGFR in circulating lung-cancer cells
-
Maheswaran S, Sequist LV, Nagrath S, et al., Detection of mutations in EGFR in circulating lung-cancer cells. New England J Med 2008; 359: 366-77.
-
(2008)
New England J Med
, vol.359
, pp. 366-377
-
-
Maheswaran, S.1
Sequist, L.V.2
Nagrath, S.3
-
14
-
-
79960860845
-
Screening for EGFR mutations in lung cancer, a report from India
-
Sahoo R, Harini VV, Babu VC, et al., Screening for EGFR mutations in lung cancer, a report from India. Lung Cancer 2011; 73: 316-9.
-
(2011)
Lung Cancer
, vol.73
, pp. 316-319
-
-
Sahoo, R.1
Harini, V.V.2
Babu, V.C.3
-
15
-
-
33645709473
-
EGFR mutations and molecularly targeted therapy: A new era in the treatment of lung cancer
-
Dowell JE, Minna JD,. EGFR mutations and molecularly targeted therapy: a new era in the treatment of lung cancer. Nat Clin Pract Oncol 2006; 3: 170-1.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 170-171
-
-
Dowell, J.E.1
Minna, J.D.2
-
17
-
-
52749083383
-
Somatic mutations of the tyrosine kinase domain of epidermal growth factor receptor and tyrosine kinase inhibitor response to TKIs in non-small cell lung cancer: An analytical database
-
Murray S, Dahabreh IJ, Linardou H, et al., Somatic mutations of the tyrosine kinase domain of epidermal growth factor receptor and tyrosine kinase inhibitor response to TKIs in non-small cell lung cancer: an analytical database. J Thoracic Oncol Official Public Inter Assoc Study Lung Cancer 2008; 3: 832-9.
-
(2008)
J Thoracic Oncol Official Public Inter Assoc Study Lung Cancer
, vol.3
, pp. 832-839
-
-
Murray, S.1
Dahabreh, I.J.2
Linardou, H.3
-
18
-
-
51049116207
-
Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response
-
Wu JY, Wu SG, Yang CH, et al., Lung cancer with epidermal growth factor receptor exon 20 mutations is associated with poor gefitinib treatment response. Clin Cancer Res Official J Am Assoc Cancer Res 2008; 14: 4877-82.
-
(2008)
Clin Cancer Res Official J Am Assoc Cancer Res
, vol.14
, pp. 4877-4882
-
-
Wu, J.Y.1
Wu, S.G.2
Yang, C.H.3
-
19
-
-
80755181069
-
Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer
-
Brugger W, Triller N, Blasinska-Morawiec M, et al., Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer. J Clin Oncol Official J Am Soc Clin Oncol 2011; 29: 4113-20.
-
(2011)
J Clin Oncol Official J Am Soc Clin Oncol
, vol.29
, pp. 4113-4120
-
-
Brugger, W.1
Triller, N.2
Blasinska-Morawiec, M.3
-
20
-
-
77649222572
-
Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: Data from the randomized phase III INTEREST trial
-
Douillard JY, Shepherd FA, Hirsh V, et al., Molecular predictors of outcome with gefitinib and docetaxel in previously treated non-small-cell lung cancer: data from the randomized phase III INTEREST trial. J Clin Oncol Official J Am Soc Clin Oncol 2010; 28: 744-52.
-
(2010)
J Clin Oncol Official J Am Soc Clin Oncol
, vol.28
, pp. 744-752
-
-
Douillard, J.Y.1
Shepherd, F.A.2
Hirsh, V.3
-
21
-
-
52049090365
-
Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21
-
Zhu CQ, da Cunha Santos G, Ding K, et al., Role of KRAS and EGFR as biomarkers of response to erlotinib in National Cancer Institute of Canada Clinical Trials Group Study BR.21. J Clin Oncol Official J Am Soc Clin Oncol 2008; 26: 4268-75.
-
(2008)
J Clin Oncol Official J Am Soc Clin Oncol
, vol.26
, pp. 4268-4275
-
-
Zhu, C.Q.1
Da Cunha Santos, G.2
Ding, K.3
-
22
-
-
78149249388
-
Personalized medicine in non-small-cell lung cancer: Is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy?
-
Roberts PJ, Stinchcombe TE, Der CJ, Socinski MA,. Personalized medicine in non-small-cell lung cancer: is KRAS a useful marker in selecting patients for epidermal growth factor receptor-targeted therapy? J Clin Oncol Official J Am Soc Clin Oncol 2010; 28: 4769-77.
-
(2010)
J Clin Oncol Official J Am Soc Clin Oncol
, vol.28
, pp. 4769-4777
-
-
Roberts, P.J.1
Stinchcombe, T.E.2
Der, C.J.3
Socinski, M.A.4
-
23
-
-
4644274700
-
Mutations and addiction to EGFR: The Achilles 'heal' of lung cancers?
-
DOI 10.1016/j.molmed.2004.08.008, PII S1471491404002163
-
Gazdar AF, Shigematsu H, Herz J, Minna JD,. Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers? Trends Mole Med 2004; 10: 481-6. (Pubitemid 39303620)
-
(2004)
Trends in Molecular Medicine
, vol.10
, Issue.10
, pp. 481-486
-
-
Gazdar, A.F.1
Shigematsu, H.2
Herz, J.3
Minna, J.D.4
|