The EGFR T790M mutation in acquired resistance to an irreversible second-generation EGFR inhibitor

Molecular Cancer Therapeutics

Volumn 11, Issue 3, 2012, Pages 784-791

  Kim, Youngwook ^a   Ko, Jeonghun ^a   Cui, ZhengYun ^a   Abolhoda, Amir ^c   Ahn, Jin Seok ^b   Ou, Sai Hong ^c   Ahn, Myung Ju ^a,b   Park, Keunchil ^a,b  

^a Samsung Medical Center   (South Korea)

^b Sungkyunkwan University School of Medicine   (South Korea)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AFATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR; ERLOTINIB; GEFITINIB; PROTEIN TYROSINE KINASE INHIBITOR;

ADULT; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER RECURRENCE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG RESISTANCE; FEMALE; GENE DOSAGE; GENE MUTATION; HUMAN; HUMAN CELL; LUNG CANCER; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; TREATMENT RESPONSE; TUMOR XENOGRAFT;

ADENOCARCINOMA; ADULT; ANIMALS; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE, NEOPLASM; FEMALE; HUMANS; LUNG NEOPLASMS; MICE; MICE, INBRED BALB C; MICE, NUDE; MUTATION; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; TREATMENT OUTCOME; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84859418112     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-11-0750     Document Type: Article

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