-
1
-
-
70349758510
-
Src kinases as therapeutic targets for cancer
-
Kim LC, Song L, Haura EB. Src kinases as therapeutic targets for cancer. Nat Rev Clin Oncol 2009;6:587-95.
-
(2009)
Nat Rev Clin Oncol
, vol.6
, pp. 587-95
-
-
Kim, L.C.1
Song, L.2
Haura, E.B.3
-
2
-
-
78049495513
-
Phase II study of dasatinib in patients with advanced non-small-cell lung cancer
-
Johnson FM, Bekele BN, Feng L, et al. Phase II study of dasatinib in patients with advanced non-small-cell lung cancer. J Clin Oncol 2010;28:4609-15.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4609-15
-
-
Johnson, F.M.1
Bekele, B.N.2
Feng, L.3
-
4
-
-
33745243692
-
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
-
DOI 10.1158/0008-5472.CAN-05-4620
-
Song L, Morris M, Bagui T, et al. Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res 2006;66:5542-8. (Pubitemid 43927102)
-
(2006)
Cancer Research
, vol.66
, Issue.11
, pp. 5542-5548
-
-
Song, L.1
Morris, M.2
Bagui, T.3
Lee, F.Y.4
Jove, R.5
Haura, E.B.6
-
5
-
-
33847009160
-
Src-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines
-
DOI 10.2353/ajpath.2007.060706
-
Zhang J, Kalyankrishna S, Wislez M, et al. SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines. Am J Pathol 2007;170:366-76. (Pubitemid 47339214)
-
(2007)
American Journal of Pathology
, vol.170
, Issue.1
, pp. 366-376
-
-
Zhang, J.1
Kalyankrishna, S.2
Wislez, M.3
Thilaganathan, N.4
Saigal, B.5
Wei, W.6
Ma, L.7
Wistuba, I.I.8
Johnson, F.M.9
Kurie, J.M.10
-
6
-
-
67649600824
-
SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy
-
Leung EL, Tam IY, Tin VP, et al. SRC promotes survival and invasion of lung cancers with epidermal growth factor receptor abnormalities and is a potential candidate for molecular-targeted therapy. Mol Cancer Res 2009;7:923-32.
-
(2009)
Mol Cancer Res
, vol.7
, pp. 923-32
-
-
Leung, E.L.1
Tam, I.Y.2
Tin, V.P.3
-
7
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. J Clin Oncol 2009;27:4247-53.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4247-53
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
-
8
-
-
78049425319
-
Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer
-
Kwak EL, Bang YJ, Camidge DR, et al. Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer. N Engl J Med 2010;363:1693-703.
-
(2010)
N Engl J Med
, vol.363
, pp. 1693-703
-
-
Kwak, E.L.1
Bang, Y.J.2
Camidge, D.R.3
-
9
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. N Engl J Med 2010;362:2380-8.
-
(2010)
N Engl J Med
, vol.362
, pp. 2380-8
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
-
10
-
-
33845490014
-
Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer
-
DOI 10.1056/NEJMoa061884
-
Sandler A, Gray R, Perry MC, et al. Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancer. N Engl J Med 2006;355:2542-50. (Pubitemid 44917502)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.24
, pp. 2542-2550
-
-
Sandler, A.1
Gray, R.2
Perry, M.C.3
Brahmer, J.4
Schiller, J.H.5
Dowlati, A.6
Lilenbaum, R.7
Johnson, D.H.8
-
11
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228-47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-47
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
-
12
-
-
4344646459
-
Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer
-
DOI 10.1200/JCO.2004.11.057
-
Perez-Soler R, Chachoua A, Hammond LA, et al. Determinants of tumor response and survival with erlotinib in patients with non-small-cell lung cancer. J Clin Oncol 2004;22:3238-47. (Pubitemid 41103678)
-
(2004)
Journal of Clinical Oncology
, vol.22
, Issue.16
, pp. 3238-3247
-
-
Perez-Soler, R.1
Chachoua, A.2
Hammond, L.A.3
Rowinsky, E.K.4
Huberman, M.5
Karp, D.6
Rigas, J.7
Clark, G.M.8
Santabarbara, P.9
Bonomi, P.10
-
13
-
-
0142055937
-
Efficacy of Gefitinib, an Inhibitor of the Epidermal Growth Factor Receptor Tyrosine Kinase, in Symptomatic Patients with Non-Small Cell Lung Cancer: A Randomized Trial
-
DOI 10.1001/jama.290.16.2149
-
Kris MG, Natale RB, Herbst RS, et al. Efficacy of gefitinib, an inhibitor of the epidermal growth factor receptor tyrosine kinase, in symptomatic patients with non-small cell lung cancer: a randomized trial. JAMA 2003;290:2149-58. (Pubitemid 37432975)
-
(2003)
Journal of the American Medical Association
, vol.290
, Issue.16
, pp. 2149-2158
-
-
Kris, M.G.1
Natale, R.B.2
Herbst, R.S.3
Lynch Jr., T.J.4
Prager, D.5
Belani, C.P.6
Schiller, J.H.7
Kelly, K.8
Spiridonidis, H.9
Sandler, A.10
Albain, K.S.11
Cella, D.12
Wolf, M.K.13
Averbuch, S.D.14
Ochs, J.J.15
Kay, A.C.16
-
14
-
-
34248140107
-
Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: The Tarceva lung cancer investigation trial
-
DOI 10.1200/JCO.2005.05.1474
-
Gatzemeier U, Pluzanska A, Szczesna A, et al. Phase III study of erlotinib in combination with cisplatin and gemcitabine in advanced non-small-cell lung cancer: the Tarceva Lung Cancer Investigation Trial. J Clin Oncol 2007;25:1545-52. (Pubitemid 46733081)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.12
, pp. 1545-1552
-
-
Gatzemeier, U.1
Pluzanska, A.2
Szczesna, A.3
Kaukel, E.4
Roubec, J.5
De Rosa, F.6
Milanowski, J.7
Karnicka-Mlodkowski, H.8
Pesek, M.9
Serwatowski, P.10
Ramlau, R.11
Janaskova, T.12
Vansteenkiste, J.13
Strausz, J.14
Manikhas, G.M.15
Von Pawel, J.16
-
15
-
-
24944440830
-
TRIBUTE: A phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer
-
Herbst RS, Prager D, Hermann R, et al. TRIBUTE: a phase III trial of erlotinib hydrochloride (OSI-774) combined with carboplatin and paclitaxel chemotherapy in advanced non-small-cell lung cancer. J Clin Oncol 2005;23:5892-9.
-
(2005)
J Clin Oncol
, vol.23
, pp. 5892-9
-
-
Herbst, R.S.1
Prager, D.2
Hermann, R.3
-
16
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
DOI 10.1016/S0140-6736(05)67625-8, PII S0140673605676258
-
Thatcher N, Chang A, Parikh P, et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005;366:1527-37. (Pubitemid 41540110)
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Pereira, J.R.4
Ciuleanu, T.5
Von Pawel, J.6
Thongprasert, S.7
Tan, E.H.8
Pemberton, K.9
Archer, V.10
Carroll, K.11
-
17
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
DOI 10.1056/NEJMoa040938
-
Lynch TJ, Bell DW, Sordella R, et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 2004;350:2129-39. (Pubitemid 38637993)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
Gurubhagavatula, S.4
Okimoto, R.A.5
Brannigan, B.W.6
Harris, P.L.7
Haserlat, S.M.8
Supko, J.G.9
Haluska, F.G.10
Louis, D.N.11
Christiani, D.C.12
Settleman, J.13
Haber, D.A.14
-
18
-
-
22044453790
-
Erlotinib in lung cancer - Molecular and clinical predictors of outcome
-
DOI 10.1056/NEJMoa050736
-
Tsao MS, Sakurada A, Cutz JC, et al. Erlotinib in lung cancer - molecular and clinical predictors of outcome. N Engl J Med 2005;353:133-44. (Pubitemid 41058345)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.2
, pp. 133-144
-
-
Tsao, M.-S.1
Sakurada, A.2
Cutz, J.-C.3
Zhu, C.-Q.4
Kamel-Reid, S.5
Squire, J.6
Lorimer, I.7
Zhang, T.8
Liu, N.9
Daneshmand, M.10
Marrano, P.11
Da Cunha Santos, G.12
Lagarde, A.13
Richardson, F.14
Seymour, L.15
Whitehead, M.16
Ding, K.17
Pater, J.18
Shepherd, F.A.19
-
19
-
-
69949162760
-
Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma
-
Mok TS, Wu YL, Thongprasert S, et al. Gefitinib or carboplatin-paclitaxel in pulmonary adenocarcinoma. N Engl J Med 2009;361:947-57.
-
(2009)
N Engl J Med
, vol.361
, pp. 947-57
-
-
Mok, T.S.1
Wu, Y.L.2
Thongprasert, S.3
-
20
-
-
70949093847
-
Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin
-
Ceppi P, Papotti M, Monica V, et al. Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin. Mol Cancer Ther 2009;8:3066-74.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3066-74
-
-
Ceppi, P.1
Papotti, M.2
Monica, V.3
-
21
-
-
77950491674
-
Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer
-
Haura EB, Tanvetyanon T, Chiappori A, et al. Phase I/II study of the Src inhibitor dasatinib in combination with erlotinib in advanced non-small-cell lung cancer. J Clin Oncol 2010;28:1387-94
-
(2010)
J Clin Oncol
, vol.28
, pp. 1387-94
-
-
Haura, E.B.1
Tanvetyanon, T.2
Chiappori, A.3
|