메뉴 건너뛰기




Volumn , Issue , 2011, Pages 583-603

Contributions of genetically modified mouse models to understanding the physiology and pathophysiology of the 25-hydroxyvitamin D-1-alpha hydroxylase enzyme (1α(OH)ase) and the vitamin d receptor (VDR)

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84870814684     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-381978-9.10033-2     Document Type: Chapter
Times cited : (6)

References (218)
  • 1
    • 0031755168 scopus 로고    scopus 로고
    • Current understanding of the molecular actions of vitamin D
    • Jones G., Strugnell S.A., DeLuca H.F. Current understanding of the molecular actions of vitamin D. Physiol. Rev. 1998, 78:1193-1231.
    • (1998) Physiol. Rev. , vol.78 , pp. 1193-1231
    • Jones, G.1    Strugnell, S.A.2    DeLuca, H.F.3
  • 2
    • 0034282412 scopus 로고    scopus 로고
    • Regulation of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression by parathyroid hormone and 1,25-dihydroxyvitamin D3
    • Brenza H.L., DeLuca H.F. Regulation of 25-hydroxyvitamin D3 1alpha-hydroxylase gene expression by parathyroid hormone and 1,25-dihydroxyvitamin D3. Arch. Biochem. Biophys. 2000, 381:143-152.
    • (2000) Arch. Biochem. Biophys. , vol.381 , pp. 143-152
    • Brenza, H.L.1    DeLuca, H.F.2
  • 3
    • 9244240970 scopus 로고    scopus 로고
    • Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders
    • Bai X., Miao D., Li J., Goltzman D., Karaplis A.C. Transgenic mice overexpressing human fibroblast growth factor 23 (R176Q) delineate a putative role for parathyroid hormone in renal phosphate wasting disorders. Endocrinology 2004, 145:5269-5279.
    • (2004) Endocrinology , vol.145 , pp. 5269-5279
    • Bai, X.1    Miao, D.2    Li, J.3    Goltzman, D.4    Karaplis, A.C.5
  • 5
    • 3042592233 scopus 로고    scopus 로고
    • Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism
    • Adams J.S., Chen H., Chun R., Gacad M.A., Encinas C., Ren S., et al. Response element binding proteins and intracellular vitamin D binding proteins: novel regulators of vitamin D trafficking, action and metabolism. J. Steroid Biochem. Mol. Biol. 2004, 89-90:461-465.
    • (2004) J. Steroid Biochem. Mol. Biol. , vol.89-90 , pp. 461-465
    • Adams, J.S.1    Chen, H.2    Chun, R.3    Gacad, M.A.4    Encinas, C.5    Ren, S.6
  • 6
    • 52649121742 scopus 로고    scopus 로고
    • Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention
    • Haussler M.R., Haussler C.A., Bartik L., Whitfield G.K., Hsieh J.C., Slater S., et al. Vitamin D receptor: molecular signaling and actions of nutritional ligands in disease prevention. Nutr. Rev. 2008, 66(10 Suppl. 2):S98-S112.
    • (2008) Nutr. Rev. , vol.66 , Issue.10 SUPPL. 2
    • Haussler, M.R.1    Haussler, C.A.2    Bartik, L.3    Whitfield, G.K.4    Hsieh, J.C.5    Slater, S.6
  • 7
    • 0031635492 scopus 로고    scopus 로고
    • Molecular cloning of (25-OH D)-1 alpha-hydroxylase: an approach to the understanding of vitamin D pseudo-deficiency
    • Glorieux F.H., St-Arnaud R. Molecular cloning of (25-OH D)-1 alpha-hydroxylase: an approach to the understanding of vitamin D pseudo-deficiency. Recent Prog. Horm. Res. 1998, 53:341-349.
    • (1998) Recent Prog. Horm. Res. , vol.53 , pp. 341-349
    • Glorieux, F.H.1    St-Arnaud, R.2
  • 8
    • 39749113799 scopus 로고    scopus 로고
    • Vitamin D-resistant diseases
    • Liberman U.A. Vitamin D-resistant diseases. J. Bone Miner. Res. 2007, 22(Suppl. 2):V105-V107.
    • (2007) J. Bone Miner. Res. , vol.22 , Issue.SUPPL. 2
    • Liberman, U.A.1
  • 9
    • 0035912707 scopus 로고    scopus 로고
    • Targeted ablation of the 25-hydroxyvitamin D 1alpha-hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction
    • Panda D.K., Miao D., Tremblay M.L., Sirois J., Farookhi R., Hendy G.N., et al. Targeted ablation of the 25-hydroxyvitamin D 1alpha-hydroxylase enzyme: evidence for skeletal, reproductive, and immune dysfunction. Proc. Natl. Acad. Sci. USA 2001, 98:7498-7503.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7498-7503
    • Panda, D.K.1    Miao, D.2    Tremblay, M.L.3    Sirois, J.4    Farookhi, R.5    Hendy, G.N.6
  • 10
    • 0034984919 scopus 로고    scopus 로고
    • Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets
    • Dardenne O., Prud'homme J., Arabian A., Glorieux F.H., St-Arnaud R. Targeted inactivation of the 25-hydroxyvitamin D(3)-1(alpha)-hydroxylase gene (CYP27B1) creates an animal model of pseudovitamin D-deficiency rickets. Endocrinology 2001, 142:3135-3141.
    • (2001) Endocrinology , vol.142 , pp. 3135-3141
    • Dardenne, O.1    Prud'homme, J.2    Arabian, A.3    Glorieux, F.H.4    St-Arnaud, R.5
  • 11
    • 0030763857 scopus 로고    scopus 로고
    • Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning
    • Yoshizawa T., Handa Y., Uematsu Y., Takeda S., Sekine K., Yoshihara Y., et al. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat. Genet. 1997, 16:391-396.
    • (1997) Nat. Genet. , vol.16 , pp. 391-396
    • Yoshizawa, T.1    Handa, Y.2    Uematsu, Y.3    Takeda, S.4    Sekine, K.5    Yoshihara, Y.6
  • 12
    • 0030610422 scopus 로고    scopus 로고
    • Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia
    • Li Y.C., Pirro A.E., Amling M., Delling G., Baron R., Bronson R., et al. Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc. Natl. Acad. Sci. USA 1997, 94:9831-9835.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 9831-9835
    • Li, Y.C.1    Pirro, A.E.2    Amling, M.3    Delling, G.4    Baron, R.5    Bronson, R.6
  • 14
    • 85047685376 scopus 로고    scopus 로고
    • Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D
    • Erben R.G., Soegiarto D., Weber K., Zeitz U., Lieberherr M., Gniadecki R., et al. Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. Mol. Endocrinol. 2002, 16:1524-1537.
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1524-1537
    • Erben, R.G.1    Soegiarto, D.2    Weber, K.3    Zeitz, U.4    Lieberherr, M.5    Gniadecki, R.6
  • 15
    • 1942469303 scopus 로고    scopus 로고
    • Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis
    • Panda D.K., Miao D., Bolivar I., Li J., Huo R., Hendy G.N., et al. Inactivation of the 25-hydroxyvitamin D 1α-hydroxylase and vitamin D receptor demonstrates independent and interdependent effects of calcium and vitamin D on skeletal and mineral homeostasis. J. Biol. Chem. 2004, 279:16754-16766.
    • (2004) J. Biol. Chem. , vol.279 , pp. 16754-16766
    • Panda, D.K.1    Miao, D.2    Bolivar, I.3    Li, J.4    Huo, R.5    Hendy, G.N.6
  • 19
    • 0041419383 scopus 로고    scopus 로고
    • Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1, 25 dihydroxyvitamin D3 in the intestine and kidney of mice
    • Song Y., Peng X., Porta A., Takanaga H., Peng J.B., Hediger M.A., et al. Calcium transporter 1 and epithelial calcium channel messenger ribonucleic acid are differentially regulated by 1, 25 dihydroxyvitamin D3 in the intestine and kidney of mice. Endocrinology 2003, 144:3885-3894.
    • (2003) Endocrinology , vol.144 , pp. 3885-3894
    • Song, Y.1    Peng, X.2    Porta, A.3    Takanaga, H.4    Peng, J.B.5    Hediger, M.A.6
  • 20
    • 0037312599 scopus 로고    scopus 로고
    • Vitamin D receptor (VDR) knockout mice reveal VDR-independent regulation of intestinal calcium absorption and ECaC2 and calbindin D9k mRNA
    • Song Y., Kato S., Fleet J.C. Vitamin D receptor (VDR) knockout mice reveal VDR-independent regulation of intestinal calcium absorption and ECaC2 and calbindin D9k mRNA. J. Nutr. 2003, 133:374-380.
    • (2003) J. Nutr. , vol.133 , pp. 374-380
    • Song, Y.1    Kato, S.2    Fleet, J.C.3
  • 21
    • 0021430990 scopus 로고
    • Effect of vitamin D 3 on duodenal calcium absorption in vivo during early development
    • Dostal L.A., Toverud S.U. Effect of vitamin D 3 on duodenal calcium absorption in vivo during early development. Am. J. Physiol. 1984, 246:G528-G534.
    • (1984) Am. J. Physiol. , vol.246
    • Dostal, L.A.1    Toverud, S.U.2
  • 22
    • 0019407615 scopus 로고
    • Appearance of the intestinal cytosolic receptor for 1,25-dihydroxyvitamin D3 during neonatal development in the rat
    • Halloran B.P., DeLuca H.F. Appearance of the intestinal cytosolic receptor for 1,25-dihydroxyvitamin D3 during neonatal development in the rat. J. Biol. Chem. 1981, 256:7338-7342.
    • (1981) J. Biol. Chem. , vol.256 , pp. 7338-7342
    • Halloran, B.P.1    DeLuca, H.F.2
  • 23
    • 0012884005 scopus 로고    scopus 로고
    • Rescue of the pseudo-Vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyVitamin D3: biochemical, histomorphometric, and biomechanical analyses
    • Dardenne O., Prudhomme J., Hacking S.A., Glorieux F.H. Rescue of the pseudo-Vitamin D deficiency rickets phenotype of CYP27B1-deficient mice by treatment with 1,25-dihydroxyVitamin D3: biochemical, histomorphometric, and biomechanical analyses. J. Bone Miner. Res. 2003, 18:637-643.
    • (2003) J. Bone Miner. Res. , vol.18 , pp. 637-643
    • Dardenne, O.1    Prudhomme, J.2    Hacking, S.A.3    Glorieux, F.H.4
  • 24
    • 0000994630 scopus 로고    scopus 로고
    • Analysis of vitamin D-dependent calcium-binding proteion messenger ribonucleic acid expression in mice lacking the vitamin D receptor
    • Li Y.C., Pirro A.E., Demay M.B. Analysis of vitamin D-dependent calcium-binding proteion messenger ribonucleic acid expression in mice lacking the vitamin D receptor. Endocrinology 1998, 139:847-851.
    • (1998) Endocrinology , vol.139 , pp. 847-851
    • Li, Y.C.1    Pirro, A.E.2    Demay, M.B.3
  • 25
    • 22144456722 scopus 로고    scopus 로고
    • Vitamin D receptor is required for dietary calcium-induced repression of calbindin-D9k expression in mice
    • Bolt M.J., Cao L.P., Kong J., Sitrin M.D., Li Y.C. Vitamin D receptor is required for dietary calcium-induced repression of calbindin-D9k expression in mice. J. Nutr. Biochem. 2005, 16:286-290.
    • (2005) J. Nutr. Biochem. , vol.16 , pp. 286-290
    • Bolt, M.J.1    Cao, L.P.2    Kong, J.3    Sitrin, M.D.4    Li, Y.C.5
  • 26
    • 33846505390 scopus 로고    scopus 로고
    • Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene
    • Bianco S.D., Peng J.B., Takangar H., Suzuki Y., Crescenzi A., Kos C.H., et al. Marked disturbance of calcium homeostasis in mice with targeted disruption of the Trpv6 calcium channel gene. J. Bone Miner. Res. 2007, 22:274-285.
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 274-285
    • Bianco, S.D.1    Peng, J.B.2    Takangar, H.3    Suzuki, Y.4    Crescenzi, A.5    Kos, C.H.6
  • 27
    • 44249113292 scopus 로고    scopus 로고
    • Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k
    • Benn N.S., Ajibade D., Porta A., Dhawan P., Hediger M., Peng J.B., et al. Active intestinal calcium transport in the absence of transient receptor potential vanilloid type 6 and calbindin-D9k. Endocrinology 2008, 149:3196-3205.
    • (2008) Endocrinology , vol.149 , pp. 3196-3205
    • Benn, N.S.1    Ajibade, D.2    Porta, A.3    Dhawan, P.4    Hediger, M.5    Peng, J.B.6
  • 29
    • 38749151578 scopus 로고    scopus 로고
    • Phenotype of a calbindin-D9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model
    • Lee G.S., Lee K.Y., Choi K.C., Ryu Y.H., Paik S.G., Oh G.T., et al. Phenotype of a calbindin-D9k gene knockout is compensated for by the induction of other calcium transporter genes in a mouse model. J. Bone Miner. Res. 2007, 22:1968-1978.
    • (2007) J. Bone Miner. Res. , vol.22 , pp. 1968-1978
    • Lee, G.S.1    Lee, K.Y.2    Choi, K.C.3    Ryu, Y.H.4    Paik, S.G.5    Oh, G.T.6
  • 30
    • 48249098867 scopus 로고    scopus 로고
    • Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes
    • Fujita H., Sugimoto K., Inatomi S., Maeda T., Osani M., Uchiyama Y., et al. Tight junction proteins claudin-2 and -12 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Mol. Biol. Cell 2008, 19:1912-1921.
    • (2008) Mol. Biol. Cell , vol.19 , pp. 1912-1921
    • Fujita, H.1    Sugimoto, K.2    Inatomi, S.3    Maeda, T.4    Osani, M.5    Uchiyama, Y.6
  • 31
    • 0034830518 scopus 로고    scopus 로고
    • Effects of vitamin D receptor inactivation on the expression of the calbindins and calcium metabolism
    • Li Y.C., Bolt M.J., Cao L.P., Sitrin M.D. Effects of vitamin D receptor inactivation on the expression of the calbindins and calcium metabolism. Am. J. Physiol. Endocrinol. Metab. 2001, 281:E558-E564.
    • (2001) Am. J. Physiol. Endocrinol. Metab. , vol.281
    • Li, Y.C.1    Bolt, M.J.2    Cao, L.P.3    Sitrin, M.D.4
  • 32
    • 0036720339 scopus 로고    scopus 로고
    • Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3-1α-hydroxylase knockout mice
    • Hoenderop J.G., Dardenne O., van Abel M., van der Kemp A.W., van Os C.H., St Arnaud R., et al. Modulation of renal Ca2+ transport protein genes by dietary Ca2+ and 1,25-dihydroxyvitamin D3 in 25-hydroxyvitamin D3-1α-hydroxylase knockout mice. FASEB J. 2002, 16:1398-1406.
    • (2002) FASEB J. , vol.16 , pp. 1398-1406
    • Hoenderop, J.G.1    Dardenne, O.2    van Abel, M.3    van der Kemp, A.W.4    van Os, C.H.5    St Arnaud, R.6
  • 35
    • 0031019589 scopus 로고    scopus 로고
    • Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene
    • Airaksinen M.S., Eilers J., Garaschuk O., Thoenen H., Konnerth A., Meyer M. Ataxia and altered dendritic calcium signaling in mice carrying a targeted null mutation of the calbindin D28k gene. Proc. Natl. Acad. Sci. USA 1997, 94:1488-1493.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 1488-1493
    • Airaksinen, M.S.1    Eilers, J.2    Garaschuk, O.3    Thoenen, H.4    Konnerth, A.5    Meyer, M.6
  • 36
    • 33746656282 scopus 로고    scopus 로고
    • Functionally improved bone in calbindin-D28k knockout mice
    • Margolis D.S., Kim D., Szivek J.A., Lai L.W., Lien Y.H. Functionally improved bone in calbindin-D28k knockout mice. Bone 2006, 39:477-484.
    • (2006) Bone , vol.39 , pp. 477-484
    • Margolis, D.S.1    Kim, D.2    Szivek, J.A.3    Lai, L.W.4    Lien, Y.H.5
  • 37
    • 0033918672 scopus 로고    scopus 로고
    • The role of calbindin and 1,25-dihydroxyvitamin D3 in the kidney
    • Sooy K., Kohut J., Christakos S. The role of calbindin and 1,25-dihydroxyvitamin D3 in the kidney. Curr. Opin. Nephrol. Hypertens. 2000, 9:341-347.
    • (2000) Curr. Opin. Nephrol. Hypertens. , vol.9 , pp. 341-347
    • Sooy, K.1    Kohut, J.2    Christakos, S.3
  • 38
    • 10644251674 scopus 로고    scopus 로고
    • Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D29k
    • Zheng W., Xie Y., Li G., Kong J., Feng J.Q., Li Y.C. Critical role of calbindin-D28k in calcium homeostasis revealed by mice lacking both vitamin D receptor and calbindin-D29k. J. Biol. Chem. 2004, 279:52406-52413.
    • (2004) J. Biol. Chem. , vol.279 , pp. 52406-52413
    • Zheng, W.1    Xie, Y.2    Li, G.3    Kong, J.4    Feng, J.Q.5    Li, Y.C.6
  • 39
    • 33750741415 scopus 로고    scopus 로고
    • Critical role of the epithelial Ca2+ channel TRPV5 in active Ca2+ reabsorption as revealed by TRPV5/calbindin-D28k knockout mice
    • Gkika D., Hsu Y.J., van der Kemp A.W., Christakos S., Bindels R.J., Hoenderop J.G. Critical role of the epithelial Ca2+ channel TRPV5 in active Ca2+ reabsorption as revealed by TRPV5/calbindin-D28k knockout mice. J. Am. Soc. Nephrol. 2006, 17:3020-3027.
    • (2006) J. Am. Soc. Nephrol. , vol.17 , pp. 3020-3027
    • Gkika, D.1    Hsu, Y.J.2    van der Kemp, A.W.3    Christakos, S.4    Bindels, R.J.5    Hoenderop, J.G.6
  • 40
    • 0035349728 scopus 로고    scopus 로고
    • Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization
    • Koushik S.V., Wang J., Rogers R., Moskophidis D., Lambert N.A., Creazzo T.L., et al. Targeted inactivation of the sodium-calcium exchanger (Ncx1) results in the lack of a heartbeat and abnormal myofibrillar organization. FASEB J. 2001, 15:1209-1211.
    • (2001) FASEB J. , vol.15 , pp. 1209-1211
    • Koushik, S.V.1    Wang, J.2    Rogers, R.3    Moskophidis, D.4    Lambert, N.A.5    Creazzo, T.L.6
  • 41
    • 4043055834 scopus 로고    scopus 로고
    • Targeted ablation of plasma membrane Ca2+-ATPase (PMCA)1 and 4 indicates a major housekeeping role in hyperactivated sperm motility and male fertility for PMCA4
    • Okunade G.W., Miller M.L., Pyne G.J., Sutliff R.L., O'Connor K.T., Neumann J.C., et al. Targeted ablation of plasma membrane Ca2+-ATPase (PMCA)1 and 4 indicates a major housekeeping role in hyperactivated sperm motility and male fertility for PMCA4. J. Biol. Chem. 2004, 279:33742-33750.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33742-33750
    • Okunade, G.W.1    Miller, M.L.2    Pyne, G.J.3    Sutliff, R.L.4    O'Connor, K.T.5    Neumann, J.C.6
  • 43
    • 0034711286 scopus 로고    scopus 로고
    • Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat
    • Wakimoto K., Kobayashi K., Kuro O., Yao A., Iwamoto T., Yanaka N., et al. Targeted disruption of Na+/Ca2+ exchanger gene leads to cardiomyocyte apoptosis and defects in heartbeat. J. Biol. Chem. 2000, 275:36991-36998.
    • (2000) J. Biol. Chem. , vol.275 , pp. 36991-36998
    • Wakimoto, K.1    Kobayashi, K.2    Kuro, O.3    Yao, A.4    Iwamoto, T.5    Yanaka, N.6
  • 44
    • 0028988403 scopus 로고
    • Structure-function relationships in the Vitamin D endocrine system
    • Bouillon R., Okamura W.H., Norman A.W. Structure-function relationships in the Vitamin D endocrine system. Endocr. Rev. 1995, 6:200-257.
    • (1995) Endocr. Rev. , vol.6 , pp. 200-257
    • Bouillon, R.1    Okamura, W.H.2    Norman, A.W.3
  • 45
    • 0038636398 scopus 로고    scopus 로고
    • Vitamin D: more than a "bone-a-fide" hormone
    • Sutton A.L., MacDonald P.N. Vitamin D: more than a "bone-a-fide" hormone. Molec. Endocrinol. 2003, 17:777-791.
    • (2003) Molec. Endocrinol. , vol.17 , pp. 777-791
    • Sutton, A.L.1    MacDonald, P.N.2
  • 46
    • 0035138842 scopus 로고    scopus 로고
    • Extracellular calcium sensing and extracellular calcium signaling
    • Brown E.M., MacLeod R.J. Extracellular calcium sensing and extracellular calcium signaling. Physiol. Rev. 2001, 81:239-297.
    • (2001) Physiol. Rev. , vol.81 , pp. 239-297
    • Brown, E.M.1    MacLeod, R.J.2
  • 48
    • 0021270891 scopus 로고
    • Parathyroid hormone: biochemical aspects of biosynthesis, secretion, action, and metabolism
    • Habener J.F., Rosenblatt M., Potts J.T. Parathyroid hormone: biochemical aspects of biosynthesis, secretion, action, and metabolism. Physiol. Rev. 1984, 64:985-1053.
    • (1984) Physiol. Rev. , vol.64 , pp. 985-1053
    • Habener, J.F.1    Rosenblatt, M.2    Potts, J.T.3
  • 49
    • 0032570574 scopus 로고    scopus 로고
    • RNA protein binding and post-transcriptional regulation of PTH gene expression by calcium and phosphate
    • Moallem E., Kilav R., Silver J., Naveh-Many T. RNA protein binding and post-transcriptional regulation of PTH gene expression by calcium and phosphate. J. Biol. Chem. 1998, 273:5253-5259.
    • (1998) J. Biol. Chem. , vol.273 , pp. 5253-5259
    • Moallem, E.1    Kilav, R.2    Silver, J.3    Naveh-Many, T.4
  • 50
    • 0021732481 scopus 로고
    • The effects of calcium and Vitamin D metabolites on cytoplasmic mRNA coding for pre-proparathyroid hormone in isolated parathyroid cells
    • Russell J., Silver J., Sherwood L.M. The effects of calcium and Vitamin D metabolites on cytoplasmic mRNA coding for pre-proparathyroid hormone in isolated parathyroid cells. Trans. Assoc. Am. Physicians. 1984, 97:296-303.
    • (1984) Trans. Assoc. Am. Physicians. , vol.97 , pp. 296-303
    • Russell, J.1    Silver, J.2    Sherwood, L.M.3
  • 51
    • 0024335479 scopus 로고
    • Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells
    • Kremer R., Bolivar I., Goltzman D., Hendy G.N. Influence of calcium and 1,25-dihydroxycholecalciferol on proliferation and proto-oncogene expression in primary cultures of bovine parathyroid cells. Endocrinology 1989, 125:935-941.
    • (1989) Endocrinology , vol.125 , pp. 935-941
    • Kremer, R.1    Bolivar, I.2    Goltzman, D.3    Hendy, G.N.4
  • 52
    • 70350719354 scopus 로고    scopus 로고
    • Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology
    • Meir T., Levi R., Lieben L., Libutti S., Carmeliet G., Bouillon R., et al. Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the receptor in parathyroid physiology. Am. J. Physiol. Renal. Physiol. 2009, 297:F1192-F1198.
    • (2009) Am. J. Physiol. Renal. Physiol. , vol.297
    • Meir, T.1    Levi, R.2    Lieben, L.3    Libutti, S.4    Carmeliet, G.5    Bouillon, R.6
  • 53
    • 0036251217 scopus 로고    scopus 로고
    • Parathyroid hormone is essential for normal fetal bone formation
    • Miao D., He B., Karaplis A.C., Goltzman D. Parathyroid hormone is essential for normal fetal bone formation. J. Clin. Invest. 2002, 109:1173-1182.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1173-1182
    • Miao, D.1    He, B.2    Karaplis, A.C.3    Goltzman, D.4
  • 54
    • 84884780416 scopus 로고    scopus 로고
    • Chapter 13. Skeletal and reproductive abnormalities in PTH-null mice
    • Eurekah.com and Kluwer Academic/Plenum Publisher, T. Naveh-Many (Ed.)
    • Miao D., He B., Lanske B., Bai X.-Y., Tong X.-K., Hendy G.N., et al. Chapter 13. Skeletal and reproductive abnormalities in PTH-null mice. Molecular Biology of the Parathyroid 2005, 179-196. Eurekah.com and Kluwer Academic/Plenum Publisher. T. Naveh-Many (Ed.).
    • (2005) Molecular Biology of the Parathyroid , pp. 179-196
    • Miao, D.1    He, B.2    Lanske, B.3    Bai, X.-Y.4    Tong, X.-K.5    Hendy, G.N.6
  • 55
    • 20444472774 scopus 로고    scopus 로고
    • Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development
    • Xue Y., Karaplis A.C., Hendy G.N., Goltzman D., Miao D. Genetic models show that parathyroid hormone and 1,25-dihydroxyvitamin D3 play distinct and synergistic roles in postnatal mineral ion homeostasis and skeletal development. Hum. Mol. Genet. 2005, 14:1515-1528.
    • (2005) Hum. Mol. Genet. , vol.14 , pp. 1515-1528
    • Xue, Y.1    Karaplis, A.C.2    Hendy, G.N.3    Goltzman, D.4    Miao, D.5
  • 56
    • 25444520761 scopus 로고    scopus 로고
    • Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1α-hydroxylase and PTH double knockout mice
    • Xue Y., Zhang Z., Karaplis A.C., Hendy G.N., Goltzman D., Miao D. Exogenous PTH-related protein and PTH improve mineral and skeletal status in 25-hydroxyvitamin D-1α-hydroxylase and PTH double knockout mice. J. Bone Miner. Res. 2005, 20:1766-1777.
    • (2005) J. Bone Miner. Res. , vol.20 , pp. 1766-1777
    • Xue, Y.1    Zhang, Z.2    Karaplis, A.C.3    Hendy, G.N.4    Goltzman, D.5    Miao, D.6
  • 57
    • 33748750344 scopus 로고    scopus 로고
    • Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1alpha-hydroxylase and parathyroid hormone null alleles
    • Xue Y., Karaplis A.C., Hendy G.N., Goltzman D., Miao D. Exogenous 1,25-dihydroxyvitamin D3 exerts a skeletal anabolic effect and improves mineral ion homeostasis in mice that are homozygous for both the 1alpha-hydroxylase and parathyroid hormone null alleles. Endocrinology 2006, 147:4801-4810.
    • (2006) Endocrinology , vol.147 , pp. 4801-4810
    • Xue, Y.1    Karaplis, A.C.2    Hendy, G.N.3    Goltzman, D.4    Miao, D.5
  • 58
    • 23944521772 scopus 로고    scopus 로고
    • Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter
    • Tenenhouse H.S. Regulation of phosphorus homeostasis by the type IIa Na/phosphate cotransporter. Annu. Rev. Nutr. 2005, 25:197-214.
    • (2005) Annu. Rev. Nutr. , vol.25 , pp. 197-214
    • Tenenhouse, H.S.1
  • 59
    • 31544469808 scopus 로고    scopus 로고
    • The renal Na/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone
    • Bacic D., Lehir M., Biber J., Kaissling B., Murer H., Wagner C.A. The renal Na/phosphate cotransporter NaPi-IIa is internalized via the receptor-mediated endocytic route in response to parathyroid hormone. Kidney Int. 2006, 69:495-503.
    • (2006) Kidney Int. , vol.69 , pp. 495-503
    • Bacic, D.1    Lehir, M.2    Biber, J.3    Kaissling, B.4    Murer, H.5    Wagner, C.A.6
  • 60
    • 0032749345 scopus 로고    scopus 로고
    • Regulation of small intestinal Na-P(i) type IIb cotransporter by dietary phosphate intake
    • Hattenhauer O., Traebert M., Murer H., Biber J. Regulation of small intestinal Na-P(i) type IIb cotransporter by dietary phosphate intake. Am. J. Physiol. 1999, 277:G756-G762.
    • (1999) Am. J. Physiol. , vol.277
    • Hattenhauer, O.1    Traebert, M.2    Murer, H.3    Biber, J.4
  • 61
    • 0036084055 scopus 로고    scopus 로고
    • Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)(2) vitamin D(3)
    • Xu H., Bai L., Collins J.F., Ghishan F.K. Age-dependent regulation of rat intestinal type IIb sodium-phosphate cotransporter by 1,25-(OH)(2) vitamin D(3). Am. J. Physiol. Cell Physiol. 2002, 282:C487-C493.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.282
    • Xu, H.1    Bai, L.2    Collins, J.F.3    Ghishan, F.K.4
  • 63
    • 12144274056 scopus 로고    scopus 로고
    • Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor and 1αOHase-deficient mice
    • Capuano P., Radanovic T., Wagner C.A., Bacic D., Kato S., Uchiyama Y., et al. Intestinal and renal adaptation to a low-Pi diet of type II NaPi cotransporters in vitamin D receptor and 1αOHase-deficient mice. Am. J. Physiol. Cell Physiol. 2005, 288:C429-C434.
    • (2005) Am. J. Physiol. Cell Physiol. , vol.288
    • Capuano, P.1    Radanovic, T.2    Wagner, C.A.3    Bacic, D.4    Kato, S.5    Uchiyama, Y.6
  • 64
    • 0033303655 scopus 로고    scopus 로고
    • Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses
    • Amling M., Priemel M., Holzmann T., Chapin K., Rueger J.M., Baron R., et al. Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology 1999, 140:4982-4987.
    • (1999) Endocrinology , vol.140 , pp. 4982-4987
    • Amling, M.1    Priemel, M.2    Holzmann, T.3    Chapin, K.4    Rueger, J.M.5    Baron, R.6
  • 65
    • 0037384951 scopus 로고    scopus 로고
    • Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1)
    • Dardenne O., Prudhomme J., Hacking S.A., Glorieux F.H. Correction of the abnormal mineral ion homeostasis with a high-calcium, high-phosphorus, high-lactose diet rescues the PDDR phenotype of mice deficient for the 25-hydroxyvitamin D-1alpha-hydroxylase (CYP27B1). Bone 2003, 32:332-340.
    • (2003) Bone , vol.32 , pp. 332-340
    • Dardenne, O.1    Prudhomme, J.2    Hacking, S.A.3    Glorieux, F.H.4
  • 68
    • 22144495738 scopus 로고    scopus 로고
    • Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes
    • Sabbagh Y., Carpenter T.O., Demay M.B. Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes. Proc. Natl. Acad. Sci. USA 2005, 102:9637-9642.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 9637-9642
    • Sabbagh, Y.1    Carpenter, T.O.2    Demay, M.B.3
  • 69
    • 37149002834 scopus 로고    scopus 로고
    • High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice
    • Rowling M.J., Gliniak C., Welsh J., Fleet J.C. High dietary vitamin D prevents hypocalcemia and osteomalacia in CYP27B1 knockout mice. J. Nutr. 2007, 137:2608-2615.
    • (2007) J. Nutr. , vol.137 , pp. 2608-2615
    • Rowling, M.J.1    Gliniak, C.2    Welsh, J.3    Fleet, J.C.4
  • 70
    • 33845296928 scopus 로고    scopus 로고
    • Vitamin receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts
    • Masuyama R., Stockmans I., Torrekens S., Van Looveren R., Maes C., Carmeliet P., et al. Vitamin receptor in chondrocytes promotes osteoclastogenesis and regulates FGF23 production in osteoblasts. J. Clin. Invest. 2006, 116:3150-3159.
    • (2006) J. Clin. Invest. , vol.116 , pp. 3150-3159
    • Masuyama, R.1    Stockmans, I.2    Torrekens, S.3    Van Looveren, R.4    Maes, C.5    Carmeliet, P.6
  • 73
    • 3042634460 scopus 로고    scopus 로고
    • Transgenic mice expressing fibroblast growth factor 23 under the control of the α1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis
    • Larsson T., Marsell R., Schipani E., Ohlsson C., Ljunggren O., Tenenhouse H.S., et al. Transgenic mice expressing fibroblast growth factor 23 under the control of the α1(I) collagen promoter exhibit growth retardation, osteomalacia, and disturbed phosphate homeostasis. Endocrinology 2004, 145:3087-3094.
    • (2004) Endocrinology , vol.145 , pp. 3087-3094
    • Larsson, T.1    Marsell, R.2    Schipani, E.3    Ohlsson, C.4    Ljunggren, O.5    Tenenhouse, H.S.6
  • 77
    • 23944501314 scopus 로고    scopus 로고
    • Role of the vitamin D receptor in FGF23 action on phosphate metabolism
    • Inoue Y., Seqawa H., Kaneko I., Yamanaka S., Kusano K., Kawakami E., et al. Role of the vitamin D receptor in FGF23 action on phosphate metabolism. Biochem. J. 2005, 390:325-331.
    • (2005) Biochem. J. , vol.390 , pp. 325-331
    • Inoue, Y.1    Seqawa, H.2    Kaneko, I.3    Yamanaka, S.4    Kusano, K.5    Kawakami, E.6
  • 78
    • 29144527562 scopus 로고    scopus 로고
    • Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23
    • Miyamoto K., Ito M., Kuwahata M., Kato S., Segawa H. Inhibition of intestinal sodium-dependent inorganic phosphate transport by fibroblast growth factor 23. Ther. Apher. Dial. 2005, 9:331-335.
    • (2005) Ther. Apher. Dial. , vol.9 , pp. 331-335
    • Miyamoto, K.1    Ito, M.2    Kuwahata, M.3    Kato, S.4    Segawa, H.5
  • 79
    • 34247545717 scopus 로고    scopus 로고
    • Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-nul animals
    • Sitara D., Razzaque M.S., St.Arnaud R., Huang W., Taguchi T., Erben R.G., et al. Genetic ablation of vitamin D activation pathway reverses biochemical and skeletal anomalies in Fgf-23-nul animals. Am. J. Pathol. 2006, 169:2161-2170.
    • (2006) Am. J. Pathol. , vol.169 , pp. 2161-2170
    • Sitara, D.1    Razzaque, M.S.2    St. Arnaud, R.3    Huang, W.4    Taguchi, T.5    Erben, R.G.6
  • 80
    • 33646238028 scopus 로고    scopus 로고
    • Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process
    • Razzaque M.S., Sitara D., Taguchi T., St Arnaud R., Lanske B. Premature aging-like phenotype in fibroblast growth factor 23 null mice is a vitamin D-mediated process. FASEB J. 2006, 20:720-722.
    • (2006) FASEB J. , vol.20 , pp. 720-722
    • Razzaque, M.S.1    Sitara, D.2    Taguchi, T.3    St Arnaud, R.4    Lanske, B.5
  • 81
    • 33846566785 scopus 로고    scopus 로고
    • Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice
    • Hesse M., Frolich L.F., Zeitz U., Lanske B., Erben R.G. Ablation of vitamin D signaling rescues bone, mineral, and glucose homeostasis in Fgf-23 deficient mice. Matrix. Biol. 2007, 26:75-84.
    • (2007) Matrix. Biol. , vol.26 , pp. 75-84
    • Hesse, M.1    Frolich, L.F.2    Zeitz, U.3    Lanske, B.4    Erben, R.G.5
  • 82
    • 33845631059 scopus 로고    scopus 로고
    • Klotho converts canonical FGF receptor into a specific receptor for FGF23
    • Urakawa I., Yamazaki Y., Shimada T., Iijima K., Hasegawa H., Okawa K., et al. Klotho converts canonical FGF receptor into a specific receptor for FGF23. Nature 2006, 444:770-774.
    • (2006) Nature , vol.444 , pp. 770-774
    • Urakawa, I.1    Yamazaki, Y.2    Shimada, T.3    Iijima, K.4    Hasegawa, H.5    Okawa, K.6
  • 83
    • 0030724491 scopus 로고    scopus 로고
    • Mutation of the mouse Klotho gene leads to a syndrome resembling aging
    • Kuro-o M., Matsumara Y., Aizawa H., Kawaguchi H., Suga T., Utsugi T., et al. Mutation of the mouse Klotho gene leads to a syndrome resembling aging. Nature 1997, 390:45-51.
    • (1997) Nature , vol.390 , pp. 45-51
    • Kuro-o, M.1    Matsumara, Y.2    Aizawa, H.3    Kawaguchi, H.4    Suga, T.5    Utsugi, T.6
  • 84
    • 33746341155 scopus 로고    scopus 로고
    • Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice
    • Razzaque M.S., Lanske B. Hypervitaminosis D and premature aging: lessons learned from Fgf23 and Klotho mutant mice. Trends Mol. Med. 2006, 12:298-305.
    • (2006) Trends Mol. Med. , vol.12 , pp. 298-305
    • Razzaque, M.S.1    Lanske, B.2
  • 85
    • 0346849707 scopus 로고    scopus 로고
    • Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system
    • Tsujikawa H., Kurotaki Y., Fujimori T., Fukuda K., Nabeshima Y. Klotho, a gene related to a syndrome resembling human premature aging, functions in a negative regulatory circuit of vitamin D endocrine system. Mol. Endocrinol. 2003, 17:2393-2403.
    • (2003) Mol. Endocrinol. , vol.17 , pp. 2393-2403
    • Tsujikawa, H.1    Kurotaki, Y.2    Fujimori, T.3    Fukuda, K.4    Nabeshima, Y.5
  • 86
    • 2142652987 scopus 로고    scopus 로고
    • 1α-Hydroxylase gene ablation and Pi supplementation inhibit renal calcification in mice homozygous for the disrupted Npt2a gene
    • Tenenhouse H.S., Gauthier C., Chau H., St Arnaud R. 1α-Hydroxylase gene ablation and Pi supplementation inhibit renal calcification in mice homozygous for the disrupted Npt2a gene. Am. J. Physiol. Renal. Physiol. 2004, 286:F675-F681.
    • (2004) Am. J. Physiol. Renal. Physiol. , vol.286
    • Tenenhouse, H.S.1    Gauthier, C.2    Chau, H.3    St Arnaud, R.4
  • 87
    • 0025923045 scopus 로고
    • 3 receptors: structure and function in transcription
    • 3 receptors: structure and function in transcription. Annu. Rev. Nutr. 1991, 11:189-216.
    • (1991) Annu. Rev. Nutr. , vol.11 , pp. 189-216
    • Pike, J.W.1
  • 88
    • 3042645085 scopus 로고    scopus 로고
    • 3-regulated gene expression by microarray analysis
    • 3-regulated gene expression by microarray analysis. J. Steroid Biochem. Mol. Biol. 2004, 89-90:239-244.
    • (2004) J. Steroid Biochem. Mol. Biol. , pp. 239-244
    • White, J.H.1
  • 89
    • 84884844755 scopus 로고    scopus 로고
    • Chapter 79: Extra-renal 1α-hydroxylase activity and human disease
    • Elsevier Academic Press, New York, D. Feldman, J.W. Pike, F.H. Glorieux (Eds.)
    • Hewison M., Adams J.S. Chapter 79: Extra-renal 1α-hydroxylase activity and human disease. Vitamin D 2005, 1379-1402. Elsevier Academic Press, New York. second ed. D. Feldman, J.W. Pike, F.H. Glorieux (Eds.).
    • (2005) Vitamin D , pp. 1379-1402
    • Hewison, M.1    Adams, J.S.2
  • 91
    • 34548634762 scopus 로고    scopus 로고
    • Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials
    • Autier P., Gandini S. Vitamin D supplementation and total mortality: a meta-analysis of randomized controlled trials. Arch. Intern. Med. 2007, 167:1730-1737.
    • (2007) Arch. Intern. Med. , vol.167 , pp. 1730-1737
    • Autier, P.1    Gandini, S.2
  • 92
    • 42449108137 scopus 로고    scopus 로고
    • The vitamin D receptor is required for iNKT cell development
    • Yu S., Cantorna M.T. The vitamin D receptor is required for iNKT cell development. Proc. Natl. Acad. Sci. USA 2008, 105:5207-5212.
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 5207-5212
    • Yu, S.1    Cantorna, M.T.2
  • 93
    • 27544513984 scopus 로고    scopus 로고
    • Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues
    • Zinser G.M., Suckow M., Welsh J. Vitamin D receptor (VDR) ablation alters carcinogen-induced tumorigenesis in mammary gland, epidermis and lymphoid tissues. J. Steroid Biochem. Mol. Biol. 2005, 97:153-164.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.97 , pp. 153-164
    • Zinser, G.M.1    Suckow, M.2    Welsh, J.3
  • 94
    • 0037364216 scopus 로고    scopus 로고
    • Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor
    • Zeitz U., Weber K., Soegiarto D.W., Wolf E., Balling R., Erben R.G. Impaired insulin secretory capacity in mice lacking a functional vitamin D receptor. FASEB J. 2003, 17:509-511.
    • (2003) FASEB J. , vol.17 , pp. 509-511
    • Zeitz, U.1    Weber, K.2    Soegiarto, D.W.3    Wolf, E.4    Balling, R.5    Erben, R.G.6
  • 95
    • 0036073755 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system
    • Li Y.C., Kong J., Wei M., Chen Z.F., Liu S.Q., Cao L.P. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. J. Clin. Invest. 2002, 110:229-238.
    • (2002) J. Clin. Invest. , vol.110 , pp. 229-238
    • Li, Y.C.1    Kong, J.2    Wei, M.3    Chen, Z.F.4    Liu, S.Q.5    Cao, L.P.6
  • 96
    • 0344943235 scopus 로고    scopus 로고
    • Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors
    • Endo I., Inoue D., Mitsui T., Umaki Y., Akaike M., Yoshizawa T., et al. Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors. Endocrinology 2003, 144:5138-5144.
    • (2003) Endocrinology , vol.144 , pp. 5138-5144
    • Endo, I.1    Inoue, D.2    Mitsui, T.3    Umaki, Y.4    Akaike, M.5    Yoshizawa, T.6
  • 97
    • 11444253492 scopus 로고    scopus 로고
    • Behavioural characterization of vitamin D receptor knockout mice
    • Burne T.H., McGrath J.J., Eyles D.W., Mackay-Sim A. Behavioural characterization of vitamin D receptor knockout mice. Behav. Brain Res. 2005, 157:299-308.
    • (2005) Behav. Brain Res. , vol.157 , pp. 299-308
    • Burne, T.H.1    McGrath, J.J.2    Eyles, D.W.3    Mackay-Sim, A.4
  • 98
    • 84884733892 scopus 로고    scopus 로고
    • Defective female reproductive function in 1,25(OH)2D deficient mice results from an indirect effect mediated by extracellular calcium and/or phosphorus
    • W. Sun, H. Xie, J. Ji, X. Zhou, D. Goltzman, D. Miao, Defective female reproductive function in 1,25(OH)2D deficient mice results from an indirect effect mediated by extracellular calcium and/or phosphorus, Am. J. Physiol. - Endocrinol. Metab. In press.
    • Am. J. Physiol. - Endocrinol. Metab. In press
    • Sun, W.1    Xie, H.2    Ji, J.3    Zhou, X.4    Goltzman, D.5    Miao, D.6
  • 99
    • 25144512533 scopus 로고    scopus 로고
    • Vitamin D analogs down-regulate plasminogen activator inhibitor-1 in human coronary artery smooth muscle cells
    • Ruth Wu-Wong J., Nakane M., Ma J., Cook A.L. Vitamin D analogs down-regulate plasminogen activator inhibitor-1 in human coronary artery smooth muscle cells. J. Thromb. Haemost. 2005, 3:1545-1546.
    • (2005) J. Thromb. Haemost. , vol.3 , pp. 1545-1546
    • Ruth Wu-Wong, J.1    Nakane, M.2    Ma, J.3    Cook, A.L.4
  • 100
    • 19944425466 scopus 로고    scopus 로고
    • Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems
    • Xiang W., Kong J., Chen S., Cao L.P., Qiao G., Zheng W., et al. Cardiac hypertrophy in vitamin D receptor knockout mice: role of the systemic and cardiac renin-angiotensin systems. Am. J. Physiol. Endocrinol. Metab. 2005, 288:E125-E132.
    • (2005) Am. J. Physiol. Endocrinol. Metab. , vol.288
    • Xiang, W.1    Kong, J.2    Chen, S.3    Cao, L.P.4    Qiao, G.5    Zheng, W.6
  • 101
    • 46249115642 scopus 로고    scopus 로고
    • Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice
    • Zhou C., Lu F., Cao K., Xu D., Goltzman D., Miao D. Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice. Kidney Int. 2008, 74:170-179.
    • (2008) Kidney Int. , vol.74 , pp. 170-179
    • Zhou, C.1    Lu, F.2    Cao, K.3    Xu, D.4    Goltzman, D.5    Miao, D.6
  • 102
    • 0030700528 scopus 로고    scopus 로고
    • Association of calcitriol and blood pressure in normotensive men
    • Kristal-Boneh E., Froom P., Harari G., Ribak J. Association of calcitriol and blood pressure in normotensive men. Hypertension 1997, 30:1289-1294.
    • (1997) Hypertension , vol.30 , pp. 1289-1294
    • Kristal-Boneh, E.1    Froom, P.2    Harari, G.3    Ribak, J.4
  • 103
    • 0029156145 scopus 로고
    • Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men
    • Lind L., Hanni A., Lithell H., Hvarfner A., Sorensen O.H., Ljunghall S. Vitamin D is related to blood pressure and other cardiovascular risk factors in middle-aged men. Am. J. Hypertens. 1995, 8:894-901.
    • (1995) Am. J. Hypertens. , vol.8 , pp. 894-901
    • Lind, L.1    Hanni, A.2    Lithell, H.3    Hvarfner, A.4    Sorensen, O.H.5    Ljunghall, S.6
  • 104
    • 0025649095 scopus 로고
    • Interaction of 1,25-dihydroxyvitamin D and plasma renin activity in high renin essential hypertension
    • Burgess E.D., Hawkins R.G., Watanabe M. Interaction of 1,25-dihydroxyvitamin D and plasma renin activity in high renin essential hypertension. Am. J. Hypertens. 1990, 3:903-905.
    • (1990) Am. J. Hypertens. , vol.3 , pp. 903-905
    • Burgess, E.D.1    Hawkins, R.G.2    Watanabe, M.3
  • 105
    • 0024587532 scopus 로고
    • Reduction of blood pressure during long-term treatment with active vitamin D (alphacalcidol) is dependent on plasma renin activity and calcium status. A double-blind, placebo-controlled study
    • Lind L., Wengle B., Wide L., Ljunghall S. Reduction of blood pressure during long-term treatment with active vitamin D (alphacalcidol) is dependent on plasma renin activity and calcium status. A double-blind, placebo-controlled study. Am. J. Hypertens. 1989, 2:20-25.
    • (1989) Am. J. Hypertens. , vol.2 , pp. 20-25
    • Lind, L.1    Wengle, B.2    Wide, L.3    Ljunghall, S.4
  • 106
    • 37549046405 scopus 로고    scopus 로고
    • Renoprotective role of the vitamin D receptor in diabetic nephropathy
    • Zhang Z., Sun L., Wang Y., Ning G., Minto A.W., Kong J., et al. Renoprotective role of the vitamin D receptor in diabetic nephropathy. Kidney Int. 2008, 73:163-171.
    • (2008) Kidney Int. , vol.73 , pp. 163-171
    • Zhang, Z.1    Sun, L.2    Wang, Y.3    Ning, G.4    Minto, A.W.5    Kong, J.6
  • 108
    • 33947230704 scopus 로고    scopus 로고
    • Characterization of heart size and blood pressure in the vitamin D receptor knockout mouse
    • Simpson R.U., Hershey S.H., Nibbelink K.A. Characterization of heart size and blood pressure in the vitamin D receptor knockout mouse. J. Steroid Biochem. Mol. Biol. 2007, 103:521-524.
    • (2007) J. Steroid Biochem. Mol. Biol. , vol.103 , pp. 521-524
    • Simpson, R.U.1    Hershey, S.H.2    Nibbelink, K.A.3
  • 111
    • 4143096123 scopus 로고    scopus 로고
    • Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice
    • Aihara K., Azuma H., Akaike M., Ikeda Y., Yamashita M., Sudo T., et al. Disruption of nuclear vitamin D receptor gene causes enhanced thrombogenicity in mice. J. Biol. Chem. 2004, 279:35798-35802.
    • (2004) J. Biol. Chem. , vol.279 , pp. 35798-35802
    • Aihara, K.1    Azuma, H.2    Akaike, M.3    Ikeda, Y.4    Yamashita, M.5    Sudo, T.6
  • 112
    • 0032997138 scopus 로고    scopus 로고
    • Targeted inactivation of vitamin D hydroxylases in mice
    • St Arnaud R. Targeted inactivation of vitamin D hydroxylases in mice. Bone 1999, 25:127-129.
    • (1999) Bone , vol.25 , pp. 127-129
    • St Arnaud, R.1
  • 113
    • 1642416884 scopus 로고    scopus 로고
    • Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism
    • Shimada T., Kakitani M., Yamazaki Y., Hasegawa H., Takeuchi Y., Fujita T., et al. Targeted ablation of Fgf23 demonstrates an essential physiological role of FGF23 in phosphate and vitamin D metabolism. J. Clin. Invest. 2004, 113:561-568.
    • (2004) J. Clin. Invest. , vol.113 , pp. 561-568
    • Shimada, T.1    Kakitani, M.2    Yamazaki, Y.3    Hasegawa, H.4    Takeuchi, Y.5    Fujita, T.6
  • 114
    • 33750904801 scopus 로고    scopus 로고
    • Vascular calcification: pathobiological mechanisms and clinical implications
    • Johnson R.C., Leopold J.A., Loscalzo J. Vascular calcification: pathobiological mechanisms and clinical implications. Circ. Res. 2006, 99:1044-1059.
    • (2006) Circ. Res. , vol.99 , pp. 1044-1059
    • Johnson, R.C.1    Leopold, J.A.2    Loscalzo, J.3
  • 115
    • 16544381338 scopus 로고    scopus 로고
    • Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease
    • Holick M.F. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am. J. Clin. Nutr. 2004, 80(Suppl. 6):S1678-S1688.
    • (2004) Am. J. Clin. Nutr. , vol.80 , Issue.SUPPL. 6
    • Holick, M.F.1
  • 116
    • 0642367252 scopus 로고    scopus 로고
    • Ecologic studies of solar UV-B radiation and cancer mortality rates
    • Grant W.B. Ecologic studies of solar UV-B radiation and cancer mortality rates. Recent Results Cancer Res. 2003, 164:371-377.
    • (2003) Recent Results Cancer Res. , vol.164 , pp. 371-377
    • Grant, W.B.1
  • 117
    • 84884778485 scopus 로고    scopus 로고
    • Frequency of vitamin D (Vit D) deficiency at breast cancer (BC) diagnosis and association with risk of distant recurrence and death in a prospective cohort study of T1-3, N0-1, and M0 BC
    • Toronto Abstract No. 511
    • Goodwin P.J. Frequency of vitamin D (Vit D) deficiency at breast cancer (BC) diagnosis and association with risk of distant recurrence and death in a prospective cohort study of T1-3, N0-1, and M0 BC. Annual Meeting of the American Society of Clinical Oncology 2008, Toronto Abstract No. 511.
    • (2008) Annual Meeting of the American Society of Clinical Oncology
    • Goodwin, P.J.1
  • 118
    • 0025204408 scopus 로고
    • Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation
    • Garland F.C., Garland C.F., Gorham E.D., Young J.F. Geographic variation in breast cancer mortality in the United States: a hypothesis involving exposure to solar radiation. Prev. Med. 1990, 19:614-622.
    • (1990) Prev. Med. , vol.19 , pp. 614-622
    • Garland, F.C.1    Garland, C.F.2    Gorham, E.D.3    Young, J.F.4
  • 119
    • 0037086547 scopus 로고    scopus 로고
    • An estimate of premature cancer mortality in the US because of inadequate doses of solar ultraviolet-B radiation
    • Grant W.B. An estimate of premature cancer mortality in the US because of inadequate doses of solar ultraviolet-B radiation. Cancer 2002, 94:1867-1875.
    • (2002) Cancer , vol.94 , pp. 1867-1875
    • Grant, W.B.1
  • 120
    • 44949096413 scopus 로고    scopus 로고
    • Re: Prospective study of vitamin D and cancer mortality in the United States
    • Garland C.F., Gorham E.D., Baggerly C.A., Garland F.C. Re: Prospective study of vitamin D and cancer mortality in the United States. J. Natl. Cancer Inst. 2008, 100:826-827.
    • (2008) J. Natl. Cancer Inst. , vol.100 , pp. 826-827
    • Garland, C.F.1    Gorham, E.D.2    Baggerly, C.A.3    Garland, F.C.4
  • 121
    • 0024575257 scopus 로고
    • Possible role for vitamin D in controlling breast cancer cell proliferation
    • Colston K.W., Berger U., Coombes R.C. Possible role for vitamin D in controlling breast cancer cell proliferation. Lancet 1989, 1:188-191.
    • (1989) Lancet , vol.1 , pp. 188-191
    • Colston, K.W.1    Berger, U.2    Coombes, R.C.3
  • 123
    • 0023256654 scopus 로고
    • Photosynthesis of vitamin D in the skin: effect of environmental and life-style variables
    • Holick M.F. Photosynthesis of vitamin D in the skin: effect of environmental and life-style variables. Fed. Proc. 1987, 46:1876-1882.
    • (1987) Fed. Proc. , vol.46 , pp. 1876-1882
    • Holick, M.F.1
  • 124
    • 26444580754 scopus 로고    scopus 로고
    • Vitamin D intakes by children and adults in the United States differ among ethnic groups
    • Moore C.E., Murphy M.M., Holick M.F. Vitamin D intakes by children and adults in the United States differ among ethnic groups. J. Nutr. 2005, 135:2478-2485.
    • (2005) J. Nutr. , vol.135 , pp. 2478-2485
    • Moore, C.E.1    Murphy, M.M.2    Holick, M.F.3
  • 127
    • 0028244853 scopus 로고
    • Effects of a new synthetic vitamin D analogue, EB 1089, on the estrogen responsive growth of human breast cancer cells
    • James S.Y., Mackay A.G., Binderup L., Colston K.W. Effects of a new synthetic vitamin D analogue, EB 1089, on the estrogen responsive growth of human breast cancer cells. J. Endocrinol. 1994, 141:555-563.
    • (1994) J. Endocrinol. , vol.141 , pp. 555-563
    • James, S.Y.1    Mackay, A.G.2    Binderup, L.3    Colston, K.W.4
  • 128
    • 0343376101 scopus 로고    scopus 로고
    • EB 1089, a novel vitamin D analog with strong antiproliferative and differentiation-inducing effects on targets cells
    • Hansen C.M., Mäenpää P.H. EB 1089, a novel vitamin D analog with strong antiproliferative and differentiation-inducing effects on targets cells. Biochem. Pharmacol. 1997, 54:1173-1179.
    • (1997) Biochem. Pharmacol. , vol.54 , pp. 1173-1179
    • Hansen, C.M.1    Mäenpää, P.H.2
  • 130
    • 1642281100 scopus 로고    scopus 로고
    • Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis
    • Holick M.F. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am. J. Clin. Nutr. 2004, 79:362-371.
    • (2004) Am. J. Clin. Nutr. , vol.79 , pp. 362-371
    • Holick, M.F.1
  • 131
    • 3042624314 scopus 로고    scopus 로고
    • Vitamin D analogs as therapeutic agents: a clinical study update
    • Wu-Wong J.R., Tian J., Goltzman D. Vitamin D analogs as therapeutic agents: a clinical study update. Curr. Opin. Investig. Drugs 2004, 5:320-326.
    • (2004) Curr. Opin. Investig. Drugs , vol.5 , pp. 320-326
    • Wu-Wong, J.R.1    Tian, J.2    Goltzman, D.3
  • 133
    • 0033565254 scopus 로고    scopus 로고
    • Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer
    • El Abdaimi K., Papavasiliou V., Rabbani S.A., Rhim J.S., Goltzman D., Kremer R. Reversal of hypercalcemia with the vitamin D analogue EB1089 in a human model of squamous cancer. Cancer Res. 1999, 59:3325-3328.
    • (1999) Cancer Res. , vol.59 , pp. 3325-3328
    • El Abdaimi, K.1    Papavasiliou, V.2    Rabbani, S.A.3    Rhim, J.S.4    Goltzman, D.5    Kremer, R.6
  • 137
    • 0027200251 scopus 로고
    • A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo
    • Haq M., Kremer R., Goltzman D., Rabbani S.A. A vitamin D analogue (EB1089) inhibits parathyroid hormone-related peptide production and prevents the development of malignancy-associated hypercalcemia in vivo. J. Clin. Invest. 1993, 91:2416-2422.
    • (1993) J. Clin. Invest. , vol.91 , pp. 2416-2422
    • Haq, M.1    Kremer, R.2    Goltzman, D.3    Rabbani, S.A.4
  • 138
    • 0028346980 scopus 로고
    • 3 analogue MC903 on secretion of interleukin-1(IL-1) and IL-8 by normal human keratinocytes and a human squamous cell carcinoma cell line (HSC-1)
    • 3 analogue MC903 on secretion of interleukin-1(IL-1) and IL-8 by normal human keratinocytes and a human squamous cell carcinoma cell line (HSC-1). J. Dermatol. Sci. 1994, 7:24-31.
    • (1994) J. Dermatol. Sci. , vol.7 , pp. 24-31
    • Zhang, J.Z.1    Maruyama, K.2    Ono, I.3    Iwatsuki, K.4    Kaneko, F.5
  • 139
    • 0034742488 scopus 로고    scopus 로고
    • Inhibitory effects of 1,25-dihydroxyvitamin D(3) on the G(1)-S phase-controlling machinery
    • Jensen S.S., Madsen M.W., Lukas J., Binderup L., Bartek J. Inhibitory effects of 1,25-dihydroxyvitamin D(3) on the G(1)-S phase-controlling machinery. Mol. Endocrinol. 2001, 15:1370-1380.
    • (2001) Mol. Endocrinol. , vol.15 , pp. 1370-1380
    • Jensen, S.S.1    Madsen, M.W.2    Lukas, J.3    Binderup, L.4    Bartek, J.5
  • 140
    • 0030065422 scopus 로고    scopus 로고
    • Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937
    • Liu M., Lee M.H., Cohen M., Bommakanti M., Freedman L.P. Transcriptional activation of the Cdk inhibitor p21 by vitamin D3 leads to the induced differentiation of the myelomonocytic cell line U937. Genes Dev. 1996, 10:142-153.
    • (1996) Genes Dev. , vol.10 , pp. 142-153
    • Liu, M.1    Lee, M.H.2    Cohen, M.3    Bommakanti, M.4    Freedman, L.P.5
  • 141
    • 0001208875 scopus 로고    scopus 로고
    • Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells
    • Wang Q.M., Jones J.B., Studzinski G.P. Cyclin-dependent kinase inhibitor p27 as a mediator of the G1-S phase block induced by 1,25-dihydroxyvitamin D3 in HL60 cells. Cancer Res. 1996, 56:264-267.
    • (1996) Cancer Res. , vol.56 , pp. 264-267
    • Wang, Q.M.1    Jones, J.B.2    Studzinski, G.P.3
  • 143
    • 13844266142 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D(3) is a preventive factor in the metastasis of lung cancer
    • Nakagawa K., Kawaura A., Kato S., Takeda E., Okano T. 1,25-Dihydroxyvitamin D(3) is a preventive factor in the metastasis of lung cancer. Carcinogenesis 2005, 26:429-440.
    • (2005) Carcinogenesis , vol.26 , pp. 429-440
    • Nakagawa, K.1    Kawaura, A.2    Kato, S.3    Takeda, E.4    Okano, T.5
  • 145
    • 33847390758 scopus 로고    scopus 로고
    • Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis
    • Flynn G., Chung I., Yu W.D., Romano M., Modzelewski R.A., Johnson C.S., et al. Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis. Oncology 2006, 70:447-457.
    • (2006) Oncology , vol.70 , pp. 447-457
    • Flynn, G.1    Chung, I.2    Yu, W.D.3    Romano, M.4    Modzelewski, R.A.5    Johnson, C.S.6
  • 146
    • 34248143459 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells
    • Ben Shoshan M., Amir S., Dang D.T., Dang L.H., Weisman Y., Mabjeesh N.J. 1,25-Dihydroxyvitamin D3 (Calcitriol) inhibits hypoxia-inducible factor-1/vascular endothelial growth factor pathway in human cancer cells. Mol. Cancer. Ther. 2007, 6:1433-1439.
    • (2007) Mol. Cancer. Ther. , vol.6 , pp. 1433-1439
    • Ben Shoshan, M.1    Amir, S.2    Dang, D.T.3    Dang, L.H.4    Weisman, Y.5    Mabjeesh, N.J.6
  • 147
    • 22344433065 scopus 로고    scopus 로고
    • 22-Oxa-1,25-dihydroxyvitamin D3 inhibits metastasis and angiogenesis in lung cancer
    • Nakagawa K., Sasaki Y., Kato S., Kubodera N., Okano T. 22-Oxa-1,25-dihydroxyvitamin D3 inhibits metastasis and angiogenesis in lung cancer. Carcinogenesis 2005, 26:1044-1054.
    • (2005) Carcinogenesis , vol.26 , pp. 1044-1054
    • Nakagawa, K.1    Sasaki, Y.2    Kato, S.3    Kubodera, N.4    Okano, T.5
  • 148
    • 3042640526 scopus 로고    scopus 로고
    • Metastatic growth of lung cancer cells is extremely reduced in vitamin D receptor knockout mice
    • Nakagawa K., Kawaura A., Kato S., Takeda E., Okano T. Metastatic growth of lung cancer cells is extremely reduced in vitamin D receptor knockout mice. J. Steroid Biochem. Mol. Biol. 2004, 89-90:545-547.
    • (2004) J. Steroid Biochem. Mol. Biol. , pp. 545-547
    • Nakagawa, K.1    Kawaura, A.2    Kato, S.3    Takeda, E.4    Okano, T.5
  • 149
    • 0345084462 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 inhibits tenascin-C expression in mammary epithelial cells
    • Gonzalez-Sancho J.M., Alvarez-Dolado M., Munoz A. 1,25-Dihydroxyvitamin D3 inhibits tenascin-C expression in mammary epithelial cells. FEBS Lett. 1998, 426:225-228.
    • (1998) FEBS Lett. , vol.426 , pp. 225-228
    • Gonzalez-Sancho, J.M.1    Alvarez-Dolado, M.2    Munoz, A.3
  • 152
    • 0033624888 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D3, the prohormone of 1,25-dihydroxyvitamin D3, inhibits the proliferation of primary prostatic epithelial cells
    • Barreto A.M., Schwartz G.G., Woodruff R., Cramer S.D. 25-Hydroxyvitamin D3, the prohormone of 1,25-dihydroxyvitamin D3, inhibits the proliferation of primary prostatic epithelial cells. Cancer Epidemiol. Biomarkers Prev. 2000, 9:265-270.
    • (2000) Cancer Epidemiol. Biomarkers Prev. , vol.9 , pp. 265-270
    • Barreto, A.M.1    Schwartz, G.G.2    Woodruff, R.3    Cramer, S.D.4
  • 153
    • 1442314711 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells
    • Lou Y.R., Laaksi I., Sylvala H., Blauer M., Tammera T.L.J., Ylikomi T., et al. 25-Hydroxyvitamin D3 is an active hormone in human primary prostatic stromal cells. FASEB J. 2004, 18:332-334.
    • (2004) FASEB J. , vol.18 , pp. 332-334
    • Lou, Y.R.1    Laaksi, I.2    Sylvala, H.3    Blauer, M.4    Tammera, T.L.J.5    Ylikomi, T.6
  • 155
    • 10044272155 scopus 로고    scopus 로고
    • Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain
    • Eyles D.W., Smith S., Kinobe R., Hewison M., McGrath J.J. Distribution of the vitamin D receptor and 1 alpha-hydroxylase in human brain. J. Chem. Neuroanat. 2005, 29:21-30.
    • (2005) J. Chem. Neuroanat. , vol.29 , pp. 21-30
    • Eyles, D.W.1    Smith, S.2    Kinobe, R.3    Hewison, M.4    McGrath, J.J.5
  • 156
  • 157
    • 27544509096 scopus 로고    scopus 로고
    • Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment
    • Townsend K., Evans K.N., Campbell M.J., Colston K.W., Adams J.S., Hewison M., et al. Biological actions of extra-renal 25-hydroxyvitamin D-1alpha-hydroxylase and implications for chemoprevention and treatment. J. Steroid Biochem. Mol. Biol. 2005, 97:103-109.
    • (2005) J. Steroid Biochem. Mol. Biol. , vol.97 , pp. 103-109
    • Townsend, K.1    Evans, K.N.2    Campbell, M.J.3    Colston, K.W.4    Adams, J.S.5    Hewison, M.6
  • 159
    • 0034129516 scopus 로고    scopus 로고
    • Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene
    • Albertson D.G., Ylstra B., Segraves R., Collins C., Dairkee S.H., Kowbel D., et al. Quantitative mapping of amplicon structure by array CGH identifies CYP24 as a candidate oncogene. Nat. Genet. 2000, 25:144-146.
    • (2000) Nat. Genet. , vol.25 , pp. 144-146
    • Albertson, D.G.1    Ylstra, B.2    Segraves, R.3    Collins, C.4    Dairkee, S.H.5    Kowbel, D.6
  • 160
    • 26444588692 scopus 로고    scopus 로고
    • Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice
    • Tangpricha V., Spina C., Yao M., Chen T.C., Wolfe M.M., Holick M.F., et al. Vitamin D deficiency enhances the growth of MC-26 colon cancer xenografts in Balb/c mice. J. Nutr. 2005, 135:2350-2354.
    • (2005) J. Nutr. , vol.135 , pp. 2350-2354
    • Tangpricha, V.1    Spina, C.2    Yao, M.3    Chen, T.C.4    Wolfe, M.M.5    Holick, M.F.6
  • 161
    • 0036963428 scopus 로고    scopus 로고
    • Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis
    • Zinser G.M., Sundberg J.P., Welsh J. Vitamin D(3) receptor ablation sensitizes skin to chemically induced tumorigenesis. Carcinogenesis 2002, 23:2103-2109.
    • (2002) Carcinogenesis , vol.23 , pp. 2103-2109
    • Zinser, G.M.1    Sundberg, J.P.2    Welsh, J.3
  • 162
    • 77954763192 scopus 로고    scopus 로고
    • Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status
    • Mordan-McCombs S., Brown T., Wang W.L., Gaupel A.C., Welsh J., Tenniswood M. Tumor progression in the LPB-Tag transgenic model of prostate cancer is altered by vitamin D receptor and serum testosterone status. J. Steroid Biochem. Mol. Biol. 2010, 121:368-371.
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.121 , pp. 368-371
    • Mordan-McCombs, S.1    Brown, T.2    Wang, W.L.3    Gaupel, A.C.4    Welsh, J.5    Tenniswood, M.6
  • 163
    • 84884738436 scopus 로고    scopus 로고
    • 3) 1α-hydroxylase in a human melanoma metastatic tumour cells enhances invasion in vitro and skeletal metastasis in vivo
    • 3) 1α-hydroxylase in a human melanoma metastatic tumour cells enhances invasion in vitro and skeletal metastasis in vivo. J. Bone Miner. Res. 2006, 21s1:1100.
    • (2006) J. Bone Miner. Res. , pp. 1100
    • Huang, D.C.1    Yang, X.F.2    Horst, R.L.3    Kremer, R.4
  • 164
    • 0142244181 scopus 로고    scopus 로고
    • Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases
    • Lin E.Y., Jones J.G., Li P., Zhu L., Whitney K.D., Muller W.J., et al. Progression to malignancy in the polyoma middle T oncoprotein mouse breast cancer model provides a reliable model for human diseases. Am. J. Pathol. 2003, 163:2113-2126.
    • (2003) Am. J. Pathol. , vol.163 , pp. 2113-2126
    • Lin, E.Y.1    Jones, J.G.2    Li, P.3    Zhu, L.4    Whitney, K.D.5    Muller, W.J.6
  • 169
    • 0023837301 scopus 로고
    • Specific tissue targeting of polyoma virus oncogenicity in athymic nude mice
    • Berebbi M., Dandolo L., Hassoun J., Bernard A.M., Blangy D. Specific tissue targeting of polyoma virus oncogenicity in athymic nude mice. Oncogene 1988, 2:149-156.
    • (1988) Oncogene , vol.2 , pp. 149-156
    • Berebbi, M.1    Dandolo, L.2    Hassoun, J.3    Bernard, A.M.4    Blangy, D.5
  • 170
    • 0026717977 scopus 로고
    • Characterization of the mammary hyperplasia, dysplasia, and neoplasia induced in athymic female adult mice by polyomavirus
    • Haslam S.Z., Wirth J.J., Counterman L.J., Fluck M.M. Characterization of the mammary hyperplasia, dysplasia, and neoplasia induced in athymic female adult mice by polyomavirus. Oncogene 1992, 7:1295-1303.
    • (1992) Oncogene , vol.7 , pp. 1295-1303
    • Haslam, S.Z.1    Wirth, J.J.2    Counterman, L.J.3    Fluck, M.M.4
  • 171
    • 0034123593 scopus 로고    scopus 로고
    • Mammary gland neoplasia: insights from transgenic mouse models
    • Siegel P.M., Hardy W.R., Muller W.J. Mammary gland neoplasia: insights from transgenic mouse models. Bioessays 2000, 22:554-563.
    • (2000) Bioessays , vol.22 , pp. 554-563
    • Siegel, P.M.1    Hardy, W.R.2    Muller, W.J.3
  • 172
    • 0034696171 scopus 로고    scopus 로고
    • Signal transduction in mammary tumorigenesis: a transgenic perspective
    • Dankort D.L., Muller W.J. Signal transduction in mammary tumorigenesis: a transgenic perspective. Oncogene 2000, 19:1038-1044.
    • (2000) Oncogene , vol.19 , pp. 1038-1044
    • Dankort, D.L.1    Muller, W.J.2
  • 174
    • 84884770641 scopus 로고    scopus 로고
    • 3-1α-hydroxylase gene (CYP27B1) in mammary epithelial cells accelerates breast cancer development in vitamin D sufficient PyVMT transgenic mice
    • 3-1α-hydroxylase gene (CYP27B1) in mammary epithelial cells accelerates breast cancer development in vitamin D sufficient PyVMT transgenic mice. ASBMR 31st Ann. Meet. Denver 2009.
    • (2009) ASBMR 31st Ann. Meet. Denver
    • Li, J.1    St-Arnaud, R.2    Muller, W.3    Kremer, R.4
  • 175
    • 79959770233 scopus 로고    scopus 로고
    • Vitamin D in combination cancer treatment
    • Ma Y., Trump D.L., Johnson C.S. Vitamin D in combination cancer treatment. J. Cancer 2010, 1:101-107.
    • (2010) J. Cancer , vol.1 , pp. 101-107
    • Ma, Y.1    Trump, D.L.2    Johnson, C.S.3
  • 177
    • 12344300880 scopus 로고    scopus 로고
    • Vitamin D regulated keratinocyte differentiation
    • Bikle D.D. Vitamin D regulated keratinocyte differentiation. J. Cell Biochem. 2004, 92:436-444.
    • (2004) J. Cell Biochem. , vol.92 , pp. 436-444
    • Bikle, D.D.1
  • 178
    • 0036151233 scopus 로고    scopus 로고
    • Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth
    • Xie Z., Komuves L., Yu Q.C., Elalieh H., Ng D.C., Leary C., et al. Lack of the vitamin D receptor is associated with reduced epidermal differentiation and hair follicle growth. J. Invest. Dermatol. 2002, 118:11-16.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 11-16
    • Xie, Z.1    Komuves, L.2    Yu, Q.C.3    Elalieh, H.4    Ng, D.C.5    Leary, C.6
  • 179
    • 0034455280 scopus 로고    scopus 로고
    • Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice
    • Sakai Y., Demay M.B. Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice. Endocrinology 2000, 141:2043-2049.
    • (2000) Endocrinology , vol.141 , pp. 2043-2049
    • Sakai, Y.1    Demay, M.B.2
  • 180
    • 0032780531 scopus 로고    scopus 로고
    • The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets
    • Malloy P.J., Pike J.W., Feldman D. The vitamin D receptor and the syndrome of hereditary 1,25-dihydroxyvitamin D-resistant rickets. Endocr. Rev. 1999, 20:156-188.
    • (1999) Endocr. Rev. , vol.20 , pp. 156-188
    • Malloy, P.J.1    Pike, J.W.2    Feldman, D.3
  • 181
    • 0035048930 scopus 로고    scopus 로고
    • Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice
    • Sakai Y., Kishimoto J., Demay M.B. Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice. J. Clin. Invest. 2001, 107:961-966.
    • (2001) J. Clin. Invest. , vol.107 , pp. 961-966
    • Sakai, Y.1    Kishimoto, J.2    Demay, M.B.3
  • 182
    • 0035213293 scopus 로고    scopus 로고
    • Targeting expression of the human vitamin D receptor to the keratinocytes of vitamin D receptor null mice prevents alopecia
    • Chen C.H., Sakai Y., Demay M.B. Targeting expression of the human vitamin D receptor to the keratinocytes of vitamin D receptor null mice prevents alopecia. Endocrinology 2001, 142:5386-5389.
    • (2001) Endocrinology , vol.142 , pp. 5386-5389
    • Chen, C.H.1    Sakai, Y.2    Demay, M.B.3
  • 183
    • 0036226321 scopus 로고    scopus 로고
    • Targeted expression of human vitamin D receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice
    • Kong J., Li X.J., Gavin D., Jiang Y., Li Y.C. Targeted expression of human vitamin D receptor in the skin promotes the initiation of the postnatal hair follicle cycle and rescues the alopecia in vitamin D receptor null mice. J. Invest. Dermatol. 2002, 118:631-638.
    • (2002) J. Invest. Dermatol. , vol.118 , pp. 631-638
    • Kong, J.1    Li, X.J.2    Gavin, D.3    Jiang, Y.4    Li, Y.C.5
  • 184
    • 15444367410 scopus 로고    scopus 로고
    • Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis
    • Skorija K., Cox M., Sisk J.M., Dowd D.R., MacDonald P.N., Thompson C.C., et al. Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis. Mol. Endocrinol. 2005, 19:855-862.
    • (2005) Mol. Endocrinol. , vol.19 , pp. 855-862
    • Skorija, K.1    Cox, M.2    Sisk, J.M.3    Dowd, D.R.4    MacDonald, P.N.5    Thompson, C.C.6
  • 185
    • 0034800098 scopus 로고    scopus 로고
    • Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene
    • Miller J., Djabali K., Chen T., Liu Y., Ioffreda M., Lyle S., et al. Atrichia caused by mutations in the vitamin D receptor gene is a phenocopy of generalized atrichia caused by mutations in the hairless gene. J. Invest. Dermatol. 2001, 117:612-617.
    • (2001) J. Invest. Dermatol. , vol.117 , pp. 612-617
    • Miller, J.1    Djabali, K.2    Chen, T.3    Liu, Y.4    Ioffreda, M.5    Lyle, S.6
  • 186
    • 0141961566 scopus 로고    scopus 로고
    • Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling
    • Hsieh J.C., Sisk J.M., Jurutka P.W., Haussler C.A., Slater S.A., Haussler M.R., et al. Physical and functional interaction between the vitamin D receptor and hairless corepressor, two proteins required for hair cycling. J. Biol. Chem. 2003, 278:38665-38674.
    • (2003) J. Biol. Chem. , vol.278 , pp. 38665-38674
    • Hsieh, J.C.1    Sisk, J.M.2    Jurutka, P.W.3    Haussler, C.A.4    Slater, S.A.5    Haussler, M.R.6
  • 187
    • 29344450418 scopus 로고    scopus 로고
    • Hairless suppresses vitamin D receptor transactivation in human keratinocytes
    • Xie Z., Chang S., Oda Y., Bikle D.D. Hairless suppresses vitamin D receptor transactivation in human keratinocytes. Endocrinology 2006, 147:314-323.
    • (2006) Endocrinology , vol.147 , pp. 314-323
    • Xie, Z.1    Chang, S.2    Oda, Y.3    Bikle, D.D.4
  • 188
    • 0035395874 scopus 로고    scopus 로고
    • Tcf3 and Lef1 regulate lineage differentiation of multipotential stem cells in skin
    • Merrill B.J., Gat U., DasGupta R., Fuchs E. Tcf3 and Lef1 regulate lineage differentiation of multipotential stem cells in skin. Genes Dev. 2001, 15:1688-1705.
    • (2001) Genes Dev. , vol.15 , pp. 1688-1705
    • Merrill, B.J.1    Gat, U.2    DasGupta, R.3    Fuchs, E.4
  • 189
    • 34547215387 scopus 로고    scopus 로고
    • Vitamin D receptor is essential for normal keratinocyte stem cell function
    • Cianferroti L., Cox M., Skorija K., Demay M.B. Vitamin D receptor is essential for normal keratinocyte stem cell function. Proc. Natl. Acad. Sci. USA 2007, 104:9428-9433.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 9428-9433
    • Cianferroti, L.1    Cox, M.2    Skorija, K.3    Demay, M.B.4
  • 190
    • 2342571726 scopus 로고    scopus 로고
    • 25-Hydroxyvitamin D-1α-hydroxylase is required for optimal epidermal differentiation and permeability homeostasis
    • Bikle D.D., Chang S., Crumtine D., Elalieh H., Man M.Q., Choi E.H., et al. 25-Hydroxyvitamin D-1α-hydroxylase is required for optimal epidermal differentiation and permeability homeostasis. J. Invest. Dermatol. 2004, 122:984-992.
    • (2004) J. Invest. Dermatol. , vol.122 , pp. 984-992
    • Bikle, D.D.1    Chang, S.2    Crumtine, D.3    Elalieh, H.4    Man, M.Q.5    Choi, E.H.6
  • 192
    • 0034652314 scopus 로고    scopus 로고
    • Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system
    • Veldman C.M., Cantorna M.T., DeLuca H.F. Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Arch. Biochem. Biophys. 2000, 374:334-338.
    • (2000) Arch. Biochem. Biophys. , vol.374 , pp. 334-338
    • Veldman, C.M.1    Cantorna, M.T.2    DeLuca, H.F.3
  • 193
    • 0034028664 scopus 로고    scopus 로고
    • Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase in murine macrophages
    • Laureys J., Rutgeerts O., Saint-Arnaud R., Bouillon R., Mathieu C. Identification and immune regulation of 25-hydroxyvitamin D-1-α-hydroxylase in murine macrophages. Clin. Exp. Immunol. 2000, 120:139-146.
    • (2000) Clin. Exp. Immunol. , vol.120 , pp. 139-146
    • Laureys, J.1    Rutgeerts, O.2    Saint-Arnaud, R.3    Bouillon, R.4    Mathieu, C.5
  • 194
    • 0030839837 scopus 로고    scopus 로고
    • γ-Interferon-induced resistance to 1,25-(OH)2D3 in human monocytes and macrophages: a mechanism for the hypercalcemia of various granulomatoses
    • Dusso A.S., Kamimura S., Gallieni M., Zhong M., Negrea L., Shapiro S., et al. γ-Interferon-induced resistance to 1,25-(OH)2D3 in human monocytes and macrophages: a mechanism for the hypercalcemia of various granulomatoses. J. Clin. Endocrinol. Metab. 1997, 82:2222-2232.
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 2222-2232
    • Dusso, A.S.1    Kamimura, S.2    Gallieni, M.3    Zhong, M.4    Negrea, L.5    Shapiro, S.6
  • 196
    • 0036194928 scopus 로고    scopus 로고
    • Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription
    • Vidal M., Ramana C.V., Dusso A.S. Stat1-vitamin D receptor interactions antagonize 1,25-dihydroxyvitamin D transcriptional activity and enhance stat1-mediated transcription. Mol. Cell Biol. 2002, 22:2777-2787.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 2777-2787
    • Vidal, M.1    Ramana, C.V.2    Dusso, A.S.3
  • 197
    • 0028972468 scopus 로고
    • Down-regulation of NF-B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3
    • Yu X.P., Bellido T., Manolagas S.C. Down-regulation of NF-B protein levels in activated human lymphocytes by 1,25-dihydroxyvitamin D3. Proc. Natl. Acad. Sci. USA 1995, 92:10990-10994.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 10990-10994
    • Yu, X.P.1    Bellido, T.2    Manolagas, S.C.3
  • 202
    • 33845720114 scopus 로고    scopus 로고
    • Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis
    • Munger K.L., Levin L.I., Hollis B.W., Howard N.S., Ascherio A. Serum 25-hydroxyvitamin D levels and risk of multiple sclerosis. JAMA 2006, 296:2832-2838.
    • (2006) JAMA , vol.296 , pp. 2832-2838
    • Munger, K.L.1    Levin, L.I.2    Hollis, B.W.3    Howard, N.S.4    Ascherio, A.5
  • 203
    • 0035802695 scopus 로고    scopus 로고
    • Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study
    • Hypponen E., Laara E., Reunanen A., Jarvelin M.R., Virtanen S.M. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 2001, 358:1500-1503.
    • (2001) Lancet , vol.358 , pp. 1500-1503
    • Hypponen, E.1    Laara, E.2    Reunanen, A.3    Jarvelin, M.R.4    Virtanen, S.M.5
  • 204
    • 0036117945 scopus 로고    scopus 로고
    • Normal myelopoiesis but abnormal T lymphocyte responses in vitamin D receptor knockout mice
    • O'Kelly J., Hisatake J., Hisatake Y., Bishop J., Norman A., Koeffler H.P. Normal myelopoiesis but abnormal T lymphocyte responses in vitamin D receptor knockout mice. J. Clin. Invest. 2002, 109:1091-1099.
    • (2002) J. Clin. Invest. , vol.109 , pp. 1091-1099
    • O'Kelly, J.1    Hisatake, J.2    Hisatake, Y.3    Bishop, J.4    Norman, A.5    Koeffler, H.P.6
  • 205
    • 33845890280 scopus 로고    scopus 로고
    • VDR-dependent regulation of mast cell maturation mediated by 1,25-dihydroxyvitamin D3
    • Baroni E., Biffi M., Benigni F., Monno A., Carlucci D., Carmeliet G., et al. VDR-dependent regulation of mast cell maturation mediated by 1,25-dihydroxyvitamin D3. J. Leukoc. Biol. 2007, 81:250-262.
    • (2007) J. Leukoc. Biol. , vol.81 , pp. 250-262
    • Baroni, E.1    Biffi, M.2    Benigni, F.3    Monno, A.4    Carlucci, D.5    Carmeliet, G.6
  • 206
    • 34247282706 scopus 로고    scopus 로고
    • Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury
    • Froicu M., Cantorna M.T. Vitamin D and the vitamin D receptor are critical for control of the innate immune response to colonic injury. BMC Immunol. 2007, 8:5.
    • (2007) BMC Immunol. , vol.8 , pp. 5
    • Froicu, M.1    Cantorna, M.T.2
  • 207
    • 0036919768 scopus 로고    scopus 로고
    • The vitamin D receptor is necessary for 1,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice
    • Meehan T.F., DeLuca H.F. The vitamin D receptor is necessary for 1,25-dihydroxyvitamin D(3) to suppress experimental autoimmune encephalomyelitis in mice. Arch. Biochem. Biophys. 2002, 408:200-204.
    • (2002) Arch. Biochem. Biophys. , vol.408 , pp. 200-204
    • Meehan, T.F.1    DeLuca, H.F.2
  • 208
    • 0029821239 scopus 로고    scopus 로고
    • 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis
    • Cantorna M.T., Hayes C.E., DeLuca H.F. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc. Natl. Acad. Sci. USA 1996, 93:7861-7864.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 7861-7864
    • Cantorna, M.T.1    Hayes, C.E.2    DeLuca, H.F.3
  • 209
    • 24744443699 scopus 로고    scopus 로고
    • Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice
    • Spach K.M., Hayes C.E. Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice. J. Immunol. 2005, 175:4119-4126.
    • (2005) J. Immunol. , vol.175 , pp. 4119-4126
    • Spach, K.M.1    Hayes, C.E.2
  • 210
    • 0037304073 scopus 로고    scopus 로고
    • Vitamin D and autoimmune diabetes
    • Zella J.B., DeLuca H.F. Vitamin D and autoimmune diabetes. J. Cell Biochem. 2003, 88:216-222.
    • (2003) J. Cell Biochem. , vol.88 , pp. 216-222
    • Zella, J.B.1    DeLuca, H.F.2
  • 211
    • 0028847946 scopus 로고
    • Prevention of type I diabetes in NOD mice by nonhypercalcemic doses of a new structural analog of 1,25-dihydroxyvitamin D3, KH1060
    • Mathieu C., Waer M., Casteels K., Laureys J., Bouillon R. Prevention of type I diabetes in NOD mice by nonhypercalcemic doses of a new structural analog of 1,25-dihydroxyvitamin D3, KH1060. Endocrinology 1995, 136:866-872.
    • (1995) Endocrinology , vol.136 , pp. 866-872
    • Mathieu, C.1    Waer, M.2    Casteels, K.3    Laureys, J.4    Bouillon, R.5
  • 212
    • 34247122819 scopus 로고    scopus 로고
    • Vitamin D receptor expression by the lung micro-environment is required for maximal induction of lung inflammation
    • Wittke A., Chang A., Froicu M., Harandi O.F., Weaver V., August A., et al. Vitamin D receptor expression by the lung micro-environment is required for maximal induction of lung inflammation. Arch. Biochem. Biophys. 2007, 460:306-313.
    • (2007) Arch. Biochem. Biophys. , vol.460 , pp. 306-313
    • Wittke, A.1    Chang, A.2    Froicu, M.3    Harandi, O.F.4    Weaver, V.5    August, A.6
  • 213
    • 35248857985 scopus 로고    scopus 로고
    • Vitamin D receptor signaling contributes to susceptibility to infection with Leishmania major
    • Ehrchen J., Helming L., Varga G., Pasche B., Loser K., Gunzer M., et al. Vitamin D receptor signaling contributes to susceptibility to infection with Leishmania major. FASEB J. 2007, 21:3208-3218.
    • (2007) FASEB J. , vol.21 , pp. 3208-3218
    • Ehrchen, J.1    Helming, L.2    Varga, G.3    Pasche, B.4    Loser, K.5    Gunzer, M.6
  • 214
    • 21744438757 scopus 로고    scopus 로고
    • Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3
    • Gombart A.F., Borregaard N., Koeffler H.P. Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J. 2005, 19:1067-1077.
    • (2005) FASEB J. , vol.19 , pp. 1067-1077
    • Gombart, A.F.1    Borregaard, N.2    Koeffler, H.P.3
  • 215
    • 33645224419 scopus 로고    scopus 로고
    • Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response
    • Liu P.T., Stenger S., Li H., Wenzel L., Tan B.H., Krutzik S.R., et al. Toll-like receptor triggering of a vitamin D-mediated human antimicrobial response. Science 2006, 311:1770-1773.
    • (2006) Science , vol.311 , pp. 1770-1773
    • Liu, P.T.1    Stenger, S.2    Li, H.3    Wenzel, L.4    Tan, B.H.5    Krutzik, S.R.6
  • 216
    • 0035881234 scopus 로고    scopus 로고
    • Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance
    • Gregori S., Casorati M., Amuchastegui S., Smiroldo S., Davalli A.M., Adorini L. Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance. J. Immunol. 2001, 167:1945-1953.
    • (2001) J. Immunol. , vol.167 , pp. 1945-1953
    • Gregori, S.1    Casorati, M.2    Amuchastegui, S.3    Smiroldo, S.4    Davalli, A.M.5    Adorini, L.6
  • 217
    • 77953943349 scopus 로고    scopus 로고
    • Vitamin D and the immune system: new perspectives on an old theme
    • Hewison M. Vitamin D and the immune system: new perspectives on an old theme. Endocrinol. Metab. Clin. North. Am. 2010, 39:365-379.
    • (2010) Endocrinol. Metab. Clin. North. Am. , vol.39 , pp. 365-379
    • Hewison, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.